Literatures

Primary Site >> Colorectal Cancer

Gene >> PLAUR

1.
Journal:	Anticancer Res. 1994 Nov-Dec;14(6B):2445-51.
Title:	Expression and release of plasminogen activators, their inhibitors and receptor by human tumor cell lines.
Author:	Buo, L\|Bjornland, K\|Karlsrud, T S\|Kvale, D\|Kjonniksen, I\|Fodstad, O\|Brandtzaeg, P\|Johansen, H T\|Aasen, A O
PMID:	7872665

2.
Journal:	FEBS Lett. 1994 Oct 17;353(2):138-42.
Title:	Human urokinase receptor expression is inhibited by amiloride and induced by tumor necrosis factor and phorbol ester in colon cancer cells.
Author:	Wang, Y\|Jones, C J\|Dang, J\|Liang, X\|Olsen, J E\|Doe, W F
PMID:	7926038

3.
Journal:	J Gastroenterol Hepatol. 1994 Jul-Aug;9(4):340-3.
Title:	Chromosomal localization of the human urokinase plasminogen activator receptor and plasminogen activator inhibitor type-2 genes: implications in colorectal cancer.
Author:	Webb, G\|Baker, M S\|Nicholl, J\|Wang, Y\|Woodrow, G\|Kruithof, E\|Doe, W F
PMID:	7948815

4.
Journal:	Cancer Res. 1995 Oct 15;55(20):4688-95.
Title:	Plasmin-catalyzed proteolysis in colorectal neoplasia.
Author:	Delbaldo, C\|Cunningham, M\|Vassalli, J D\|Sappino, A P
PMID:	7553650

5.
Journal:	Hum Pathol. 1995 Oct;26(10):1133-8.
Title:	Antigen levels of urokinase plasminogen activator and its receptor at the tumor-host interface of colorectal adenocarcinomas are related to tumor aggressiveness.
Author:	Buo, L\|Meling, G I\|Karlsrud, T S\|Johansen, H T\|Aasen, A O
PMID:	7557947

6.
Journal:	Int J Cancer. 1995 Sep 15;62(6):691-6.
Title:	Expression of urokinase receptor in various stromal-cell populations in human colon cancer: immunoelectron microscopical analysis.
Author:	Ohtani, H\|Pyke, C\|Dano, K\|Nagura, H
PMID:	7558416

7.
Journal:	Int J Cancer. 1995 Sep 4;62(5):619-26.
Title:	Butyrate regulates gene expression of the plasminogen activating system in colon cancer cells.
Author:	Antalis, T M\|Reeder, J A
PMID:	7665235

8.
Journal:	FEBS Lett. 1995 Feb 13;359(2-3):147-50.
Title:	Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post-transcription levels in colon cancer cells.
Author:	Dang, J\|Wang, Y\|Doe, W F
PMID:	7867787

9.
Journal:	Hum Genet. 1996 Jan;97(1):124-5.
Title:	A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR).
Author:	Kohonen-Corish, M R\|Wang, Y\|Doe, W F
PMID:	8557253

10.
Journal:	J Biol Chem. 1996 Sep 20;271(38):23176-84.
Title:	Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene.
Author:	Lengyel, E\|Wang, H\|Stepp, E\|Juarez, J\|Wang, Y\|Doe, W\|Pfarr, C M\|Boyd, D
PMID:	8798512

11.
Journal:	Br J Cancer. 1996 Sep;74(6):846-52.
Title:	Modulation of the plasminogen activation system by inflammatory cytokines in human colon carcinoma cells.
Author:	Tran-Thang, C\|Kruithof, E\|Lahm, H\|Schuster, W A\|Tada, M\|Sordat, B
PMID:	8826848

12.
Journal:	Clin Chem. 1997 Oct;43(10):1868-76.
Title:	ELISA determination of soluble urokinase receptor in blood from healthy donors and cancer patients.
Author:	Stephens, R W\|Pedersen, A N\|Nielsen, H J\|Hamers, M J\|Hoyer-Hansen, G\|Ronne, E\|Dybkjaer, E\|Dano, K\|Brunner, N
PMID:	9342006

13.
Journal:	Clin Exp Metastasis. 1998 Jan;16(1):9-20.
Title:	Inhibition of establishment of primary and micrometastatic tumors by a urokinase plasminogen activator receptor antagonist.
Author:	Ignar, D M\|Andrews, J L\|Witherspoon, S M\|Leray, J D\|Clay, W C\|Kilpatrick, K\|Onori, J\|Kost, T\|Emerson, D L
PMID:	9502073

14.
Journal:	Carcinogenesis. 1998 Jun;19(6):1149-51.
Title:	Urokinase receptor genotypes in colorectal cancer.
Author:	Kohonen-Corish, M\|Young, J\|Chenevix-Trench, G\|Doe, W F
PMID:	9667756

15.
Journal:	Gut. 1998 Dec;43(6):798-805.
Title:	Urokinase type plasminogen activator receptor expression in colorectal neoplasms.
Author:	Suzuki, S\|Hayashi, Y\|Wang, Y\|Nakamura, T\|Morita, Y\|Kawasaki, K\|Ohta, K\|Aoyama, N\|Kim, S R\|Itoh, H\|Kuroda, Y\|Doe, W F
PMID:	9824607

16.
Journal:	Gene Ther. 1998 Aug;5(8):1105-13.
Title:	Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice.
Author:	Li, H\|Lu, H\|Griscelli, F\|Opolon, P\|Sun, L Q\|Ragot, T\|Legrand, Y\|Belin, D\|Soria, J\|Soria, C\|Perricaudet, M\|Yeh, P
PMID:	10326034

17.
Journal:	Expert Opin Investig Drugs. 1998 Mar;7(3):391-403.
Title:	Urokinase receptor antagonists: novel agents for the treatment of cancer.
Author:	Weidle, U H\|Konig, B
PMID:	15991980

18.
Journal:	J Natl Cancer Inst. 1999 May 19;91(10):869-74.
Title:	Plasma urokinase receptor levels in patients with colorectal cancer: relationship to prognosis.
Author:	Stephens, R W\|Nielsen, H J\|Christensen, I J\|Thorlacius-Ussing, O\|Sorensen, S\|Dano, K\|Brunner, N
PMID:	10340907

19.
Journal:	Eur J Biochem. 1999 Aug;264(1):92-9.
Title:	A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor.
Author:	Dang, J\|Boyd, D\|Wang, H\|Allgayer, H\|Doe, W F\|Wang, Y
PMID:	10447677

20.
Journal:	Cancer. 1999 Dec 15;86(12):2602-11.
Title:	Larger and more invasive colorectal carcinoma contains larger amounts of plasminogen activator inhibitor type 1 and its relative ratio over urokinase receptor correlates well with tumor size.
Author:	Abe, J\|Urano, T\|Konno, H\|Erhan, Y\|Tanaka, T\|Nishino, N\|Takada, A\|Nakamura, S
PMID:	10594855

21.
Journal:	Int J Cancer. 2000 Apr 1;86(1):24-9.
Title:	Clinicopathologic significance of urokinase receptor- and MMP-9-positive stromal cells in human colorectal cancer: functional multiplicity of matrix degradation on hematogenous metastasis.
Author:	Saito, K\|Takeha, S\|Shiba, K\|Matsuno, S\|Sorsa, T\|Nagura, H\|Ohtani, H
PMID:	10728590

22.
Journal:	J Immunol Methods. 2000 Apr 21;238(1-2):133-41.
Title:	The use of the CELLection kit in the isolation of carcinoma cells from mononuclear cell suspensions.
Author:	Werther, K\|Normark, M\|Hansen, B F\|Brunner, N\|Nielsen, H J
PMID:	10758243

23.
Journal:	Int J Cancer. 2000 Sep 20;89(5):431-9.
Title:	Urokinase-type plasminogen activator and its receptor in colorectal cancer: independent prognostic factors of metastasis and cancer-specific survival and potential therapeutic targets.
Author:	Yang, J L\|Seetoo, D q\|Wang, Y\|Ranson, M\|Berney, C R\|Ham, J M\|Russell, P J\|Crowe, P J
PMID:	11008205

24.
Journal:	Mol Pathol. 2000 Dec;53(6):307-12.
Title:	Plasminogen activator system, vascular endothelial growth factor, and colorectal cancer progression.
Author:	Baker, E A\|Bergin, F G\|Leaper, D J
PMID:	11193049

25.
Journal:	Shi Yan Sheng Wu Xue Bao. 2000 Mar;33(1):21-6.
Title:	[The inhibitory effect of asODNs on the invasion of colorectal cancer cell line CCL229].
Author:	Jin, Y J\|Song, J D
PMID:	12548848

26.
Journal:	Int J Cancer. 2001 Apr 15;92(2):257-62.
Title:	Inhibition of colon cancer metastasis by a 3'- end antisense urokinase receptor mRNA in a nude mouse model.
Author:	Wang, Y\|Liang, X\|Wu, S\|Murrell, G A\|Doe, W F
PMID:	11291054

27.
Journal:	Jpn J Cancer Res. 2001 May;92(5):516-23.
Title:	Urokinase receptor and vascular endothelial growth factor are synergistically associated with the liver metastasis of colorectal cancer.
Author:	Konno, H\|Abe, J\|Kaneko, T\|Baba, M\|Shoji, A\|Sunayama, K\|Kamiya, K\|Tanaka, T\|Suzuki, S\|Nakamura, S\|Urano, T
PMID:	11376560

28.
Journal:	Thromb Res. 2001 Dec 1;104(5):309-15.
Title:	Hemostatic alterations in patients with benign and malignant colorectal disease during major abdominal surgery.
Author:	Modrau, I I\|Iversen, L L\|Thorlacius-Ussing, O O
PMID:	11738072

29.
Journal:	Int J Cancer. 2002 Jan 20;97(3):379-85.
Title:	High tumor tissue concentration of plasminogen activator inhibitor 2 (PAI-2) is an independent marker for shorter progression-free survival in patients with early stage endometrial cancer.
Author:	Nordengren, Johanna\|Fredstorp Lidebring, Margareta\|Bendahl, Par-Ola\|Brunner, Nils\|Ferno, Marten\|Hogberg, Thomas\|Stephens, Ross W\|Willen, Roger\|Casslen, Bertil
PMID:	11774293

30.
Journal:	World J Surg. 2002 Jul;26(7):767-71.
Title:	Plasmin/plasminogen system in colorectal cancer.
Author:	Berger, David H
PMID:	11965442

31.
Journal:	Scand J Clin Lab Invest. 2002;62(1):49-57.
Title:	Cytokeratin-positive cells in preoperative peripheral blood and bone marrow aspirates of patients with colorectal cancer.
Author:	Werther, K\|Normark, M\|Brunner, N\|Nielsen, H J
PMID:	12002413

32.
Journal:	Cancer Immunol Immunother. 2002 Jul;51(5):248-54.
Title:	Interferon-alpha (Intron A) upregulates urokinase-type plasminogen activator receptor gene expression.
Author:	Wu, Shanshan\|Murrell, George A C\|Wang, Yao
PMID:	12070711

33.
Journal:	Clin Exp Metastasis. 2002;19(6):527-34.
Title:	Cyclooxygenase-2 expression correlates with uPAR levels and is responsible for poor prognosis of colorectal cancer.
Author:	Konno, Hiroyuki\|Baba, Megumi\|Shoji, Tuyoshi\|Ohta, Manabu\|Suzuki, Shohati\|Nakamura, Satoshi
PMID:	12405290

34.
Journal:	APMIS. 2002 Sep;110(9):630-8.
Title:	Serum tetranectin is an independent prognostic marker in colorectal cancer and weakly correlated with plasma suPAR, plasma PAI-1 and serum CEA.
Author:	Hogdall, Claus K\|Christensen, Ib J\|Stephens, Ross W\|Sorensen, Steen\|Norgaard-Pedersen, Bent\|Nielsen, Hans J
PMID:	12529016

35.
Journal:	Cancer Res. 2003 Mar 1;63(5):1138-43.
Title:	Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.
Author:	Krishnamachary, Balaji\|Berg-Dixon, Shannon\|Kelly, Brian\|Agani, Faton\|Feldser, David\|Ferreira, Gloria\|Iyer, Narayan\|LaRusch, Jessica\|Pak, Brian\|Taghavi, Panthea\|Semenza, Gregg L
PMID:	12615733

36.
Journal:	J Surg Oncol. 2003 Mar;82(3):184-93.
Title:	Quantitative expression of protein markers of plasminogen activation system in prognosis of colorectal cancer.
Author:	Seetoo, Da-Qiang\|Crowe, Philip J\|Russell, Pamela J\|Yang, Jia-Lin
PMID:	12619063

37.
Journal:	Proteomics. 2003 Mar;3(3):288-98.
Title:	Proteomic profiling of proteins associated with urokinase plasminogen activator receptor in a colon cancer cell line using an antisense approach.
Author:	Ahmed, Nuzhat\|Oliva, Karen\|Wang, Yao\|Quinn, Michael\|Rice, Greg
PMID:	12627382

38.
Journal:	Biol Chem. 2003 Feb;384(2):257-66.
Title:	Quantitation of membrane type serine protease 1 (MT-SP1) in transformed and normal cells.
Author:	Bhatt, Ami S\|Takeuchi, Toshi\|Ylstra, Bauke\|Ginzinger, David\|Albertson, Donna\|Shuman, Marc A\|Craik, Charles S
PMID:	12675519

39.
Journal:	Eur J Cancer. 2003 May;39(7):981-8.
Title:	The plasminogen activator and matrix metalloproteinase systems in colorectal cancer: relationship to tumour pathology.
Author:	Baker, E A\|Leaper, D J
PMID:	12706368

40.
Journal:	Clin Exp Metastasis. 2003;20(4):291-300.
Title:	Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin.
Author:	Herynk, Matthew H\|Tsan, Rachael\|Radinsky, Robert\|Gallick, Gary E
PMID:	12856716

41.
Journal:	Br J Cancer. 2003 Jul 21;89(2):374-84.
Title:	Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-beta1 integrin complex in colon cancer cells.
Author:	Ahmed, N\|Oliva, K\|Wang, Y\|Quinn, M\|Rice, G
PMID:	12865932

42.
Journal:	Cancer Cell. 2003 Jul;4(1):67-79.
Title:	ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Author:	Vial, Emmanuel\|Sahai, Erik\|Marshall, Christopher J
PMID:	12892714

43.
Journal:	FASEB J. 2003 Sep;17(12):1640-7.
Title:	Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.
Author:	Pai, Rama\|Nakamura, Toshikazu\|Moon, Woo S\|Tarnawski, Andrzej S
PMID:	12958170

44.
Journal:	Clin Cancer Res. 2003 Oct 15;9(13):4935-43.
Title:	Evaluation of urinary plasminogen activator, its receptor, matrix metalloproteinase-9, and von Willebrand factor in pancreatic cancer.
Author:	Harvey, Shashi R\|Hurd, Thelma C\|Markus, Gabor\|Martinick, Maisie I\|Penetrante, Remedios M\|Tan, Dongfeng\|Venkataraman, Preeti\|DeSouza, Nisha\|Sait, Sheila N J\|Driscoll, Deborah L\|Gibbs, John F
PMID:	14581368

45.
Journal:	J Biol Chem. 2004 Jan 16;279(3):2053-62. Epub 2003 Oct 21.
Title:	RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.
Author:	Zhang, Libo\|Fogg, Darin K\|Waisman, David M
PMID:	14570893

46.
Journal:	Oncogene. 2004 Apr 22;23(19):3376-84.
Title:	Identification of Tcf-4 as a transcriptional target of p53 signalling.
Author:	Rother, Karen\|Johne, Cindy\|Spiesbach, Katja\|Haugwitz, Ulrike\|Tschop, Katrin\|Wasner, Mark\|Klein-Hitpass, Ludger\|Moroy, Tarik\|Mossner, Joachim\|Engeland, Kurt
PMID:	14990988

47.
Journal:	Mol Biol Cell. 2004 May;15(5):2156-63.
Title:	Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness.
Author:	Pai, Rama\|Tarnawski, Andrzej S\|Tran, Teresa
PMID:	15004225

48.
Journal:	Anticancer Res. 2004 May-Jun;24(3b):1981-5.
Title:	The prognostic value of plasma soluble urokinase plasminogen activator receptor (suPAR) levels in stage III ovarian cancer patients.
Author:	Begum, Farah Diba\|Hogdall, Claus K\|Kjaer, Susanne K\|Christensen, Lise\|Blaakaer, Jan\|Bock, Johannes E\|Glud, Eva\|Hoyer-Hansen, Gunilla\|Ring-Larsen, Helmer\|Hogdall, Estrid V S
PMID:	15274388

49.
Journal:
Title:	(177)Lu-Labeled DOTA-conjugated AE105 peptide (Asp-Cha-Phe-(d)Ser-(d)Arg-Tyr-Leu-Trp-Ser-CONH2)
Author:	Chopra, Arvind
PMID:	23166959

50.
Journal:	J Cell Sci. 2005 Apr 1;118(Pt 7):1493-503.
Title:	Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells.
Author:	Cavallo-Medved, Dora\|Mai, Jianxin\|Dosescu, Julie\|Sameni, Mansoureh\|Sloane, Bonnie F
PMID:	15769846

51.
Journal:	Ann Surg. 2005 May;241(5):748-56; discussion 756-8.
Title:	Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.
Author:	Bauer, Todd W\|Fan, Fan\|Liu, Wenbiao\|Johnson, Marjorie\|Parikh, Nila U\|Parry, Graham C\|Callahan, Jennifer\|Mazar, Andrew P\|Gallick, Gary E\|Ellis, Lee M
PMID:	15849510

52.
Journal:	Eur Surg Res. 2005 May-Jun;37(3):166-72.
Title:	Association of interleukin-8 and plasminogen activator system in the progression of colorectal cancer.
Author:	Terada, H\|Urano, T\|Konno, H
PMID:	16088182

53.
Journal:	Oncol Res. 2005;15(5):265-79.
Title:	A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region.
Author:	Nair, Rajesh R\|Wang, Heng\|Jamaluddin, M S\|Fokt, Izabella\|Priebe, Waldemar\|Boyd, Douglas D
PMID:	16261846

54.
Journal:	J Immunol Methods. 2006 Jan 20;308(1-2):192-202.
Title:	Specific immunofluorimetric assay detecting the chemotactic epitope of the urokinase receptor (uPAR).
Author:	Resnati, Massimo\|Pallavicini, Isabella\|Daverio, Rita\|Sidenius, Nicolai\|Bonini, Pierangelo\|Blasi, Francesco
PMID:	16386755

55.
Journal:	Biochem Biophys Res Commun. 2006 Sep 22;348(2):618-27. Epub 2006 Jul 28.
Title:	Aspirin upregulates expression of urokinase type plasminogen activator receptor (uPAR) gene in human colon cancer cells through AP1.
Author:	Jamaluddin, Md Saha
PMID:	16893520

56.
Journal:	Cancer Res. 2006 Aug 15;66(16):7957-67.
Title:	Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression.
Author:	Yang, Lin\|Avila, Hector\|Wang, Heng\|Trevino, Jose\|Gallick, Gary E\|Kitadai, Yasuhiko\|Sasaki, Takamitsu\|Boyd, Douglas D
PMID:	16912170

57.
Journal:	BMC Cancer. 2006 Aug 18;6:211.
Title:	Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Author:	Kim, Tae-Dong\|Song, Kyoung-Sub\|Li, Ge\|Choi, Hoon\|Park, Hae-Duck\|Lim, Kyu\|Hwang, Byung-Doo\|Yoon, Wan-Hee
PMID:	16916471

58.
Journal:	Int J Colorectal Dis. 2007 May;22(5):515-20.
Title:	Different matrix micro-environments in colon cancer and diverticular disease.
Author:	Klinge, U\|Rosch, R\|Junge, K\|Krones, C J\|Stumpf, M\|Lynen-Jansen, P\|Mertens, P R\|Schumpelick, V
PMID:	17021746

59.
Journal:	J Thromb Haemost. 2007 Feb;5(2):403-11.
Title:	Domain 5 of kininogen inhibits proliferation of human colon cancer cell line (HCT-116) by interfering with G1/S in the cell cycle.
Author:	Bior, A D\|Pixley, R A\|Colman, R W
PMID:	17155949

60.
Journal:	Mol Cancer Res. 2007 May;5(5):485-96.
Title:	Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer.
Author:	Leupold, Jorg H\|Asangani, Irfan\|Maurer, Gabriele D\|Lengyel, Ernst\|Post, Stefan\|Allgayer, Heike
PMID:	17510314

61.
Journal:	J Pathol. 2007 Nov;213(3):266-74.
Title:	A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice.
Author:	Ploplis, V A\|Tipton, H\|Menchen, H\|Castellino, F J
PMID:	17893885

62.
Journal:	Cancer. 2008 Feb 1;112(3):495-502.
Title:	Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer.
Author:	Zlobec, Inti\|Minoo, Parham\|Baumhoer, Daniel\|Baker, Kristi\|Terracciano, Luigi\|Jass, Jeremy R\|Lugli, Alessandro
PMID:	18076013

63.
Journal:	Acta Biochim Pol. 2008;55(2):357-63. Epub 2008 May 29.
Title:	Antigen levels of urokinase-type plasminogen activator receptor and its gene polymorphism related to microvessel density in colorectal cancer.
Author:	Przybylowska, Karolina\|Szemraj, Janusz\|Kulig, Andrzej\|Dziki, Adam\|Ulanska, Joanna\|Blasiak, Janusz
PMID:	18511987

64.
Journal:	Cancer Res. 2008 Jul 1;68(13):5086-95.
Title:	Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
Author:	Pai, Rama\|Dunlap, Debra\|Qing, Jing\|Mohtashemi, Iman\|Hotzel, Kathy\|French, Dorothy M
PMID:	18593907

65.
Journal:	Hum Pathol. 2008 Oct;39(10):1483-94.
Title:	Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Bertoni, Francesco\|Kwee, Ivo\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18619649

66.
Journal:	J Proteome Res. 2008 Nov;7(11):4792-806.
Title:	Differential proteome expression associated with urokinase plasminogen activator receptor (uPAR) suppression in malignant epithelial cancer.
Author:	Saldanha, Rohit G\|Xu, Ning\|Molloy, Mark P\|Veal, Duncan A\|Baker, Mark S
PMID:	18808175

67.
Journal:	J Clin Pathol. 2009 Nov;62(11):986-97.
Title:	New time-dependent approach to analyse the prognostic significance of immunohistochemical biomarkers in colon cancer and diffuse large B-cell lymphoma.
Author:	Adams, H\|Tzankov, A\|Lugli, A\|Zlobec, I
PMID:	18977805

68.
Journal:	Int J Cancer. 2009 Apr 15;124(8):1860-70.
Title:	Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases.
Author:	Illemann, Martin\|Bird, Nigel\|Majeed, Ali\|Laerum, Ole D\|Lund, Leif R\|Dano, Keld\|Nielsen, Boye Schnack
PMID:	19123477

69.
Journal:	Mol Oncol. 2009 Feb;3(1):54-66.
Title:	PCDH24-induced contact inhibition involves downregulation of beta-catenin signaling.
Author:	Ose, Rui\|Yanagawa, Toshihide\|Ikeda, Shun\|Ohara, Osamu\|Koga, Hisashi
PMID:	19383367

70.
Journal:	Cancer. 2009 Jul 15;115(14):3360-8.
Title:	Targeting the urokinase plasminogen activator receptor with a monoclonal antibody impairs the growth of human colorectal cancer in the liver.
Author:	Van Buren, George 2nd\|Gray, Michael J\|Dallas, Nikolaos A\|Xia, Ling\|Lim, Sherry J\|Fan, Fan\|Mazar, Andrew P\|Ellis, Lee M
PMID:	19484792

71.
Journal:	Biochem Pharmacol. 2009 Nov 1;78(9):1205-13.
Title:	Macrophage inhibitory cytokine-1 (MIC-1) and subsequent urokinase-type plasminogen activator mediate cell death responses by ribotoxic anisomycin in HCT-116 colon cancer cells.
Author:	Yang, Hyun\|Choi, Hye Jin\|Park, Seong Hwan\|Kim, Jong Sik\|Moon, Yuseok
PMID:	19540205

72.
Journal:	Zhonghua Yi Xue Za Zhi. 2009 May 26;89(20):1382-6.
Title:	[Effects of allicin on invasion and metastasis of colon cancer LoVo cell line in vitro].
Author:	Gao, Yong\|Liu, Yang-qing\|Cao, Wei-ke\|Chen, Xiao-fei\|Wan, Yi-yuan\|Heng, Chun\|Xu, Li-juan
PMID:	19671326

73.
Journal:	Br J Cancer. 2009 Sep 15;101(6):992-7.
Title:	Intact and cleaved forms of the urokinase receptor enhance discrimination of cancer from non-malignant conditions in patients presenting with symptoms related to colorectal cancer.
Author:	Lomholt, A F\|Hoyer-Hansen, G\|Nielsen, H J\|Christensen, I J
PMID:	19672256

74.
Journal:	Hum Pathol. 2010 Jan;41(1):70-8.
Title:	Urokinase-type plasminogen activator is a marker of aggressive phenotype and an independent prognostic factor in mismatch repair-proficient colorectal cancer.
Author:	Minoo, Parham\|Baker, Kristi\|Baumhoer, Daniel\|Terracciano, Luigi\|Lugli, Alessandro\|Zlobec, Inti
PMID:	19740518

75.
Journal:	Cancer Lett. 2010 Apr 1;290(1):123-8.
Title:	Lithocholic acid upregulates uPAR and cell invasiveness via MAPK and AP-1 signaling in colon cancer cells.
Author:	Baek, Min Kyung\|Park, Jung Sun\|Park, Ji Hye\|Kim, Mi Ha\|Kim, Ho Dong\|Bae, Woo Kyun\|Chung, Ik Joo\|Shin, Boo Ahn\|Jung, Young Do
PMID:	19782465

76.
Journal:	BioDrugs. 2010 Apr 1;24(2):131-46.
Title:	Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter.
Author:	Teimoori-Toolabi, Ladan\|Azadmanesh, Kayhan\|Amanzadeh, Amir\|Zeinali, Sirous
PMID:	20199127

77.
Journal:	Acta Oncol. 2010 Aug;49(6):805-11.
Title:	Prognostic value of intact and cleaved forms of the urokinase plasminogen activator receptor in a retrospective study of 518 colorectal cancer patients.
Author:	Lomholt, Anne Fog\|Christensen, Ib J\|Hoyer-Hansen, Gunilla\|Nielsen, Hans J
PMID:	20524776

78.
Journal:	Acta Biochim Pol. 2010;57(3):269-75. Epub 2010 Aug 19.
Title:	DNAzyme as an efficient tool to modulate invasiveness of human carcinoma cells.
Author:	Wiktorska, Magdalena\|Papiewska-Pajak, Izabela\|Okruszek, Andrzej\|Sacewicz-Hofman, Izabela\|Niewiarowska, Jolanta
PMID:	20725651

79.
Journal:	Eur J Pharmacol. 2010 Nov 10;646(1-3):22-30.
Title:	A pharmacological analysis of the cholinergic regulation of urokinase-type plasminogen activator secretion in the human colon cancer cell line, HT-29.
Author:	Novotny, Ann\|Edsparr, Karin\|Nylund, Gunnar\|Khorram-Manesh, Amir\|Albertsson, Per\|Nordgren, Svante\|Delbro, Dick S
PMID:	20727878

80.
Journal:	Clin Chem. 2010 Oct;56(10):1636-40.
Title:	A new assay for measurement of the liberated domain I of the urokinase receptor in plasma improves the prediction of survival in colorectal cancer.
Author:	Thurison, Tine\|Lomholt, Anne F\|Rasch, Morten G\|Lund, Ida K\|Nielsen, Hans J\|Christensen, Ib J\|Hoyer-Hansen, Gunilla
PMID:	20802096

81.
Journal:	Exp Toxicol Pathol. 2011 Jan;63(1-2):79-87.
Title:	Expression and activation of proteases in co-cultures.
Author:	Paduch, Roman\|Kandefer-Szerszen, Martyna
PMID:	19836935

82.
Journal:	Int J Cancer. 2011 Mar 15;128(6):1280-92.
Title:	beta-Catenin and NF-kappaB cooperate to regulate the uPA/uPAR system in cancer cells.
Author:	Moreau, Marie\|Mourah, Samia\|Dosquet, Christine
PMID:	20473943

83.
Journal:	J Biol Chem. 2011 Jul 8;286(27):24089-100.
Title:	Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
Author:	Tammali, Ravinder\|Saxena, Ashish\|Srivastava, Satish K\|Ramana, Kota V
PMID:	21576240

84.
Journal:	Mod Pathol. 2011 Oct;24(10):1404-12.
Title:	VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
Author:	Vlajnic, Tatjana\|Andreozzi, Maria Carla\|Schneider, Sandra\|Tornillo, Luigi\|Karamitopoulou, Eva\|Lugli, Alessandro\|Ruiz, Christian\|Zlobec, Inti\|Terracciano, Luigi
PMID:	21743435

85.
Journal:	Neoplasma. 2011;58(5):377-85.
Title:	Clinical significance of the plasminogen activator system in relation to grade of tumor and treatment response in colorectal carcinoma patients.
Author:	Halamkova, J\|Kiss, I\|Pavlovsky, Z\|Tomasek, J\|Jarkovsky, J\|Cech, Z\|Tucek, S\|Hanakova, L\|Moulis, M\|Zavrelova, J\|Man, M\|Benda, P\|Robek, O\|Kala, Z\|Penka, M
PMID:	21744990

86.
Journal:	Hepatogastroenterology. 2011 Nov-Dec;58(112):1918-25.
Title:	Clinical relevance of uPA, uPAR, PAI 1 and PAI 2 tissue expression and plasma PAI 1 level in colorectal carcinoma patients.
Author:	Halamkova, Jana\|Kiss, Igor\|Pavlovsky, Zdenek\|Jarkovsky, Jiri\|Tomasek, Jiri\|Tucek, Stepan\|Hanakova, Lada\|Moulis, Mojmir\|Cech, Zbynek\|Zavrelova, Jirina\|Penka, Miroslav
PMID:	22234062

87.
Journal:	Nucl Med Biol. 2012 Oct;39(7):962-9.
Title:	New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts.
Author:	Persson, Morten\|Rasmussen, Palle\|Madsen, Jacob\|Ploug, Michael\|Kjaer, Andreas
PMID:	22739362

88.
Journal:	PLoS One. 2012;7(8):e43594.
Title:	Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.
Author:	Zhuo, Jingli\|Tan, Ee Hong\|Yan, Benedict\|Tochhawng, Lalchhandami\|Jayapal, Manikandan\|Koh, Shiuan\|Tay, Hwee Kee\|Maciver, Sutherland K\|Hooi, Shing Chuan\|Salto-Tellez, Manuel\|Kumar, Alan Prem\|Goh, Yaw Chong\|Lim, Yaw Chyn\|Yap, Celestial T
PMID:	22927998

89.
Journal:	Asian Pac J Cancer Prev. 2012;13(6):2437-44.
Title:	Metastasis-associated factors facilitating the progression of colorectal cancer.
Author:	Zhang, Yao-Yao\|Chen, Bin\|Ding, Yan-Qing
PMID:	22938401

90.
Journal:	Clin Cancer Res. 2013 Jan 1;19(1):62-72.
Title:	The critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis.
Author:	Li, Dawei\|Wei, Ping\|Peng, Zhihai\|Huang, Chen\|Tang, Huamei\|Jia, Zhiliang\|Cui, Jiujie\|Le, Xiangdong\|Huang, Suyun\|Xie, Keping
PMID:	23136192

91.
Journal:	PLoS One. 2013;8(1):e51810.
Title:	Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer.
Author:	Bujanda, Luis\|Sarasqueta, Cristina\|Cosme, Angel\|Hijona, Elizabeth\|Enriquez-Navascues, Jose M\|Placer, Carlos\|Villarreal, Eloisa\|Herreros-Villanueva, Marta\|Giraldez, Maria D\|Gironella, Meritxell\|Balaguer, Francesc\|Castells, Antoni
PMID:	23300952

92.
Journal:	ISRN Biochem. 2013 Sep 12;2013:598251.
Title:	Human sprouty1 suppresses urokinase receptor-stimulated cell migration and invasion.
Author:	Mekkawy, Ahmed H\|Morris, David L
PMID:	25937961

93.
Journal:	Cancer Med. 2014 Aug;3(4):855-64.
Title:	Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer.
Author:	Illemann, Martin\|Laerum, Ole Didrik\|Hasselby, Jane Preuss\|Thurison, Tine\|Hoyer-Hansen, Gunilla\|Nielsen, Hans Jorgen\|Christensen, Ib Jarle
PMID:	24889870

94.
Journal:	PLoS One. 2014 Jul 31;9(7):e103243.
Title:	Genome-wide analysis in human colorectal cancer cells reveals ischemia-mediated expression of motility genes via DNA hypomethylation.
Author:	Skowronski, Karolina\|Andrews, Joseph\|Rodenhiser, David I\|Coomber, Brenda L
PMID:	25079072

95.
Journal:	Apoptosis. 2014 Oct;19(10):1532-44.
Title:	Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway.
Author:	Liu, Xiufeng\|Qiu, Fan\|Liu, Zhipeng\|Lan, Yan\|Wang, Kai\|Zhou, Ping-Kun\|Wang, Yao\|Hua, Zi-Chun
PMID:	25113506

96.
Journal:	BMC Cancer. 2014 Aug 30;14:639.
Title:	Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor.
Author:	Lin, Yuli\|Peng, Nana\|Zhuang, Hongqin\|Zhang, Di\|Wang, Yao\|Hua, Zi-Chun
PMID:	25175595

97.
Journal:	J Proteome Res. 2014 Dec 5;13(12):5956-64.
Title:	Characterization of the interaction between heterodimeric alphavbeta6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics.
Author:	Ahn, Seong Beom\|Mohamedali, Abidali\|Anand, Samyuktha\|Cheruku, Harish R\|Birch, Debra\|Sowmya, Gopichandran\|Cantor, David\|Ranganathan, Shoba\|Inglis, David W\|Frank, Ronald\|Agrez, Michael\|Nice, Edouard C\|Baker, Mark S
PMID:	25318615

98.
Journal:	Monoclon Antib Immunodiagn Immunother. 2014 Oct;33(5):312-8.
Title:	A8, an anti-uPA agonistic antibody, promotes metastasis of cancer cells via ERK pathway.
Author:	Song, Hyunkeun\|Lee, A-Young\|Jung, Hana\|Choi, Jae-Hyeog\|Roh, Kughwan\|Ha, Sungmin\|Kim, Kwang-Dong\|Bae, Ki-Beom\|Kang, Mi Seon\|Park, SungJae\|Choi, Il-Whan\|Seo, Su-Kil\|Park, SaeGwang
PMID:	25357998

99.
Journal:	Adv Clin Exp Med. 2014 Nov-Dec;23(6):959-67.
Title:	Soluble urokinase-type plasminogen activator receptor and ferritin concentration in patients with advanced alimentary tract carcinoma. Relationship to localization, surgical treatment and the stage of the disease--preliminary report.
Author:	Usnarska-Zubkiewicz, Lidia\|Strutynska-Karpinska, Marta\|Zubkiewicz-Kucharska, Agnieszka\|Zarebski, Pawel\|Grabowski, Krzysztof
PMID:	25618124

100.
Journal:	Clin Chim Acta. 2015 Jan 15;439:84-90.
Title:	Circulating intact and cleaved forms of the urokinase-type plasminogen activator receptor: biological variation, reference intervals and clinical useful cut-points.
Author:	Thurison, Tine\|Christensen, Ib J\|Lund, Ida K\|Nielsen, Hans J\|Hoyer-Hansen, Gunilla
PMID:	25305537

101.
Journal:	PLoS One. 2015 Feb 18;10(2):e0117786.
Title:	Epithelial and stromal cell urokinase plasminogen activator receptor expression differentially correlates with survival in rectal cancer stages B and C patients.
Author:	Ahn, Seong Beom\|Chan, Charles\|Dent, Owen F\|Mohamedali, Abidali\|Kwun, Sun Young\|Clarke, Candice\|Fletcher, Julie\|Chapuis, Pierre H\|Nice, Edouard C\|Baker, Mark S
PMID:	25692297

102.
Journal:	Oncotarget. 2015 Jun 10;6(16):14260-73.
Title:	uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery.
Author:	Boonstra, Martin C\|van Driel, Pieter B A A\|van Willigen, Danny M\|Stammes, Marieke A\|Prevoo, Hendrica A J M\|Tummers, Quirijn R J G\|Mazar, Andrew P\|Beekman, Freek J\|Kuppen, Peter J K\|van de Velde, Cornelis J H\|Lowik, Clemens W G M\|Frangioni, John V\|van Leeu
PMID:	25895028

103.
Journal:	Clin Exp Metastasis. 2015 Aug;32(6):543-54.
Title:	Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR.
Author:	Almholt, Kasper\|Laerum, Ole Didrik\|Nielsen, Boye Schnack\|Lund, Ida Katrine\|Lund, Leif Roge\|Romer, John\|Jogi, Annika
PMID:	26040548

104.
Journal:	Onco Targets Ther. 2015 Jun 19;8:1503-9.
Title:	Prognostic role of urokinase plasminogen activator receptor in gastric and colorectal cancer: A systematic review and meta-analysis.
Author:	Guo, Hong\|Ling, Chun\|Ma, Yun-Yun\|Zhou, Lan-Xia\|Zhao, Li
PMID:	26150727

105.
Journal:	Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Oct;32(5):1067-74.
Title:	[Molecular Image of Superparamagnetic Iron Oxide Nanopariticle Labeled with hATF in Colon Tumor Models].
Author:	Zhang, Shu\|Wang, Lei\|Chen, Lu\|Xu, Huayan\|Wu, Qiang\|Bi, Feng\|Gao, Fabao\|Xu, Feng
PMID:	26964313

106.
Journal:	Clin Exp Metastasis. 2016 Jun;33(5):401-16.
Title:	Adhesion molecules in peritoneal dissemination: function, prognostic relevance and therapeutic options.
Author:	Sluiter, Nina\|de Cuba, Erienne\|Kwakman, Riom\|Kazemier, Geert\|Meijer, Gerrit\|Te Velde, Elisabeth Atie
PMID:	27074785

107.
Journal:	Biochem Biophys Res Commun. 2017 Apr 29;486(2):232-238.
Title:	LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells.
Author:	Wang, Liming\|Hirohashi, Yoshihiko\|Ogawa, Tadashi\|Shen, Min\|Takeda, Rui\|Murai, Aiko\|Yamamoto, Eri\|Kubo, Terufumi\|Nakatsugawa, Munehide\|Kanaseki, Takayuki\|Tsukahara, Tomohide\|Nishidate, Toshihiko\|Okita, Kenji\|Kutomi, Goro\|Sato, Noriyuki\|Takemasa, Ichiro\|Tor
PMID:	28238780

108.
Journal:	Clin Lab. 2017 May 1;63(5):871-880.
Title:	Prognostic Role of Circulating Soluble uPAR in Various Cancers: a Systematic Review and Meta-Analysis.
Author:	Liu, K L\|Fan, J H\|Wu, Jing
PMID:	28627814

109.
Journal:	Sci Rep. 2017 Aug 24;7(1):9388.
Title:	Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors.
Author:	Mauro, Concetta Di\|Pesapane, Ada\|Formisano, Luigi\|Rosa, Roberta\|D'Amato, Valentina\|Ciciola, Paola\|Servetto, Alberto\|Marciano, Roberta\|Orsini, Roberta Clara\|Monteleone, Francesca\|Zambrano, Nicola\|Fontanini, Gabriella\|Servadio, Adele\|Pignataro, Giuseppe\|Gru
PMID:	28839232

110.
Journal:	Drug Discov Ther. 2017;11(4):212-217.
Title:	Sushi repeat-containing protein X-linked 2 promotes angiogenesis through the urokinase-type plasminogen activator receptor dependent integrin alphavbeta3/focal adhesion kinase pathways.
Author:	Liu, Kuiliang\|Fan, Jianghao\|Wu, Jing
PMID:	28867754

111.
Journal:	Clin Lab. 2017 Nov 1;63(11):1949-1953.
Title:	A Preliminary Study of the Value of Plasma microRNA-193b and Soluble Urokinase-Type Plasminogen Activator Receptor in Identifying Patients with Early-Stage Colorectal Cancer and.
Author:	Liu, K L\|Luo, J L\|Wu, J\|Wang, Y D\|Fan, H J
PMID:	29226653

112.
Journal:	Oncol Res. 2018 Jan 31.
Title:	Up-regulation of miR-324-5p inhibits proliferation and invasion of colorectal cancer cells by targeting ELAVL1.
Author:	Gu, Chijiang\|Zhang, Mingyuan\|Sun, Weiliang\|Dong, Changzheng
PMID:	29386086

113.
Journal:	Oncotarget. 2018 Jun 5;9(43):27027-27038.
Title:	Serum levels of soluble urokinase plasminogen activator receptor (suPAR) predict outcome after resection of colorectal liver metastases.
Author:	Loosen, Sven H\|Tacke, Frank\|Binnebosel, Marcel\|Leyh, Catherine\|Vucur, Mihael\|Heitkamp, Florian\|Schoening, Wenzel\|Ulmer, Tom F\|Alizai, Patrick H\|Trautwein, Christian\|Koch, Alexander\|Longerich, Thomas\|Roderburg, Christoph\|Neumann, Ulf P\|Luedde, Tom
PMID:	29930748

114.
Journal:	Mini Rev Med Chem. 2018 Aug 15. pii: MRMC-EPUB-92419.
Title:	Novel Inhibitors of Urokinase-type Plasminogen Activators: 4-(3H-imidazo[4,5-b]pyridin-2-yl)-N-Substituted Benzamide and Benzamidine Compounds.
Author:	Kus, Canan\|Ozer, Ezgi\|Korkmaz, Yesim\|Yurtcu, Erkan\|Dagalp, Rukiye
PMID:	30112993