Primary Site >> Colorectal Cancer

Gene >> PLA2G2A

Journal: Cancer Res. 1995 Dec 1;55(23):5504-6.
Title: Human homologue of a candidate for the Mom1 locus, the secretory type II phospholipase A2 (PLA2S-II), maps to 1p35-36.1/D1S199.
Author: Praml, C|Savelyeva, L|Le Paslier, D|Siracusa, L D|Buchberg, A M|Schwab, M|Amler, L C
PMID: 7585622
Journal: Cancer Res. 1995 Nov 15;55(22):5184-6.
Title: Absence of secretory phospholipase A2 gene alterations in human colorectal cancer.
Author: Riggins, G J|Markowitz, S|Wilson, J K|Vogelstein, B|Kinzler, K W
PMID: 7585570
Journal: Cancer Surv. 1995;25:335-55.
Title: Emergent issues in the genetics of intestinal neoplasia.
Author: Dove, W F|Gould, K A|Luongo, C|Moser, A R|Shoemaker, A R
PMID: 8718526
Journal: Cell. 1995 Jun 16;81(6):957-66.
Title: The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia.
Author: MacPhee, M|Chepenik, K P|Liddell, R A|Nelson, K K|Siracusa, L D|Buchberg, A M
PMID: 7781071
Journal: Nihon Rinsho. 1996 Apr;54(4):1072-7.
Title: [Genetic steps in colorectal cancer].
Author: Ichii, S|Utsunomiya, J
PMID: 8920676
Journal: Int J Cancer. 1997 Jul 17;72(2):337-9.
Title: Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines.
Author: Haluska, F G|Thiele, C|Goldstein, A|Tsao, H|Benoit, E P|Housman, D
PMID: 9219842
Journal: Hum Genet. 1997 Sep;100(3-4):345-9.
Title: Loss of the PLA2G2A gene in a sporadic colorectal tumor of a patient with a PLA2G2A germline mutation and absence of PLA2G2A germline alterations in patients with FAP.
Author: Nimmrich, I|Friedl, W|Kruse, R|Pietsch, S|Hentsch, S|Deuter, R|Winde, G|Muller, O
PMID: 9272153
Journal: Cancer Res. 1998 Feb 1;58(3):500-3.
Title: Overexpression of the nonpancreatic secretory group II PLA2 messenger RNA and protein in colorectal adenomas from familial adenomatous polyposis patients.
Author: Kennedy, B P|Soravia, C|Moffat, J|Xia, L|Hiruki, T|Collins, S|Gallinger, S|Bapat, B
PMID: 9458096
Journal: Philos Trans R Soc Lond B Biol Sci. 1998 Jun 29;353(1370):915-23.
Title: The intestinal epithelium and its neoplasms: genetic, cellular and tissue interactions.
Author: Dove, W F|Cormier, R T|Gould, K A|Halberg, R B|Merritt, A J|Newton, M A|Shoemaker, A R
PMID: 9684289
Journal: Oncogene. 1998 Oct 15;17(15):2009-12.
Title: Secretory type II phospholipase A2 (PLA2G2A) expression status in colorectal carcinoma derived cell lines and in normal colonic mucosa.
Author: Praml, C|Amler, L C|Dihlmann, S|Finke, L H|Schlag, P|Schwab, M
PMID: 9788445
Journal: Cancer Res. 1998 Nov 15;58(22):5014-8.
Title: Cloning of the human aflatoxin B1-aldehyde reductase gene at 1p35-1p36.1 in a region frequently altered in human tumor cells.
Author: Praml, C|Savelyeva, L|Perri, P|Schwab, M
PMID: 9823300
Journal: J Surg Res. 1999 Jun 1;84(1):51-6.
Title: The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells.
Author: Longo, W E|Grossmann, E M|Erickson, B|Panesar, N|Mazuski, J E|Kaminski, D L
PMID: 10334889
Journal: Cancer Res. 2000 Feb 15;60(4):1084-91.
Title: Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs.
Author: Yuan, C J|Mandal, A K|Zhang, Z|Mukherjee, A B
PMID: 10706128
Journal: Oncogene. 2000 Jun 29;19(28):3182-92.
Title: The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64.
Author: Cormier, R T|Bilger, A|Lillich, A J|Halberg, R B|Hong, K H|Gould, K A|Borenstein, N|Lander, E S|Dove, W F
PMID: 10918573
Journal: Neoplasia. 2000 Nov-Dec;2(6):514-22.
Title: Evaluation of 1p losses in primary carcinomas, local recurrences and peripheral metastases from colorectal cancer patients.
Author: Thorstensen, L|Qvist, H|Heim, S|Liefers, G J|Nesland, J M|Giercksky, K E|Lothe, R A
PMID: 11228544
Journal: Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3935-9.
Title: Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis.
Author: Hong, K H|Bonventre, J C|O'Leary, E|Bonventre, J V|Lander, E S
PMID: 11274413
Journal: Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1521-6. Epub 2002 Jan 29.
Title: Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis.
Author: Roberts, Reade B|Min, Lu|Washington, M Kay|Olsen, Sandra J|Settle, Stephen H|Coffey, Robert J|Threadgill, David W
PMID: 11818567
Journal: Mol Carcinog. 2005 Sep;44(1):31-41.
Title: Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas.
Author: Cooper, Harry S|Chang, Wen-Chi L|Coudry, Renata|Gary, Monique A|Everley, Lynette|Spittle, Cynthia S|Wang, Hao|Litwin, Sam|Clapper, Margie L
PMID: 15937958
Journal: Oncol Rep. 2006 Oct;16(4):747-54.
Title: Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon.
Author: Lee, Seungkoo|Bang, Seunghyun|Song, Kyuyoung|Lee, Inchul
PMID: 16969489
Journal: Neuropathol Appl Neurobiol. 2006 Dec;32(6):674-8.
Title: Platelet-activating factor and human meningiomas.
Author: Denizot, Y|De Armas, R|Caire, F|Pommepuy, I|Truffinet, V|Labrousse, F
PMID: 17083481
Journal: Mol Carcinog. 2007 Feb;46(2):106-16.
Title: Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth.
Author: Belinsky, Glenn S|Rajan, Thiruchandurai V|Saria, Elizabeth A|Giardina, Charles|Rosenberg, Daniel W
PMID: 17091473
Journal: Genetics. 2007 Jun;176(2):1237-44.
Title: Identification of Mom7, a novel modifier of Apc(Min/+) on mouse chromosome 18.
Author: Kwong, Lawrence N|Shedlovsky, Alexandra|Biehl, Bryan S|Clipson, Linda|Pasch, Cheri A|Dove, William F
PMID: 17435219
Journal: Anticancer Res. 2007 Sep-Oct;27(5A):3179-85.
Title: Increased expression and activity of group IIA and X secretory phospholipase A2 in peritumoral versus central colon carcinoma tissue.
Author: Tribler, Line|Jensen, Lotte T|Jorgensen, Kent|Brunner, Nils|Gelb, Michael H|Nielsen, Hans Jorgen|Jensen, Simon S
PMID: 17970059
Journal: Br J Cancer. 2008 Feb 12;98(3):587-95.
Title: Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate.
Author: Mounier, C M|Wendum, D|Greenspan, E|Flejou, J-F|Rosenberg, D W|Lambeau, G
PMID: 18212756
Journal: Front Biosci. 2008 May 1;13:4144-74.
Title: The roles of sPLA2-IIA (Pla2g2a) in cancer of the small and large intestine.
Author: Fijneman, Remond J A|Cormier, Robert T
PMID: 18508504
Journal: BMC Cancer. 2008 Nov 7;8:326.
Title: Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.
Author: Kury, Sebastien|Buecher, Bruno|Robiou-du-Pont, Sebastien|Scoul, Catherine|Colman, Helene|Le Neel, Tanguy|Le Houerou, Claire|Faroux, Roger|Ollivry, Jean|Lafraise, Bernard|Chupin, Louis-Dominique|Sebille, Veronique|Bezieau, Stephane
PMID: 18992148
Journal: Cell Oncol. 2009;31(5):345-56.
Title: Pla2g2a attenuates colon tumorigenesis in azoxymethane-treated C57BL/6 mice; expression studies reveal Pla2g2a target genes and pathways.
Author: Fijneman, Remond J A|Bade, Lindsey K|Peham, Johannes R|van de Wiel, Mark A|van Hinsbergh, Victor W M|Meijer, Gerrit A|O'Sullivan, Michael G|Cormier, Robert T
PMID: 19759415
Journal: Ann Oncol. 2009 Jul;20(7):1230-5.
Title: PLA2 (group IIA phospholipase A2) as a prognostic determinant in stage II colorectal carcinoma.
Author: Buhmeida, A|Bendardaf, R|Hilska, M|Laine, J|Collan, Y|Laato, M|Syrjanen, K|Pyrhonen, S
PMID: 19276398
Journal: Cancer Cell Int. 2010 Jun 28;10:19.
Title: Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases.
Author: Ager, Eleanor I|Chong, Way W|Wen, Shu-Wen|Christophi, Christopher
PMID: 20584290
Journal: Virchows Arch. 2010 Dec;457(6):659-67.
Title: The expression and distribution of group IIA phospholipase A2 in human colorectal tumours.
Author: Avoranta, Tuulia|Sundstrom, Jari|Korkeila, Eija|Syrjanen, Kari|Pyrhonen, Seppo|Laine, Jukka
PMID: 20938784
Journal: J Nutr Metab. 2012;2012:351796.
Title: Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats.
Author: Rondini, Elizabeth A|Bennink, Maurice R
PMID: 22496968
Journal: PLoS One. 2013;8(2):e57081.
Title: Elevated phospholipase A2 activities in plasma samples from multiple cancers.
Author: Cai, Hui|Chiorean, Elena G|Chiorean, Michael V|Rex, Douglas K|Robb, Bruce W|Hahn, Noah M|Liu, Ziyue|Loehrer, Patrick J|Harrison, Marietta L|Xu, Yan
PMID: 23451150
Journal: Genetics. 2014 Aug;197(4):1365-76.
Title: Human cancer xenografts in outbred nude mice can be confounded by polymorphisms in a modifier of tumorigenesis.
Author: Zeineldin, Maged|Jensen, Derek|Paranjape, Smita R|Parelkar, Nikhil K|Jokar, Iman|Vielhauer, George A|Neufeld, Kristi L
PMID: 24913681
Journal: Histopathology. 2015 Jun;66(7):991-1002.
Title: PLA2G2A overexpression is associated with poor therapeutic response and inferior outcome in rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy.
Author: He, Hong-Lin|Lee, Ying-En|Shiue, Yow-Ling|Lee, Sung-Wei|Lin, Li-Ching|Chen, Tzu-Ju|Wu, Ting-Feng|Li, Chien-Feng
PMID: 25393083
Journal: Cell Stem Cell. 2016 Jul 7;19(1):38-51.
Title: Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer.
Author: Schewe, Matthias|Franken, Patrick F|Sacchetti, Andrea|Schmitt, Mark|Joosten, Rosalie|Bottcher, Rene|van Royen, Martin E|Jeammet, Louise|Payre, Christine|Scott, Patricia M|Webb, Nancy R|Gelb, Michael|Cormier, Robert T|Lambeau, Gerard|Fodde, Riccardo
PMID: 27292189
Journal: Sci Rep. 2017 Sep 25;7(1):12261.
Title: Group III phospholipase A2 promotes colitis and colorectal cancer.
Author: Murase, Remi|Taketomi, Yoshitaka|Miki, Yoshimi|Nishito, Yasumasa|Saito, Moe|Fukami, Kiyoko|Yamamoto, Kei|Murakami, Makoto
PMID: 28947740