Primary Site >> Stomach Cancer

Gene >> PKM

Journal: Gastrointest Endosc. 2011 Nov;74(5):1010-8.
Title: Clinical impact of EUS-guided Trucut biopsy results on decision making for patients with gastric subepithelial tumors >/= 2 cm in diameter.
Author: Lee, Jeong Hoon|Choi, Kee Don|Kim, Mi-Young|Choi, Kwi-Sook|Kim, Do Hoon|Park, Young Soo|Kim, Kab Choong|Song, Ho June|Lee, Gin Hyug|Jung, Hwoon-Yong|Yook, Jeong Hwan|Kim, Byung Sik|Kang, Yoon-Koo|Kim, Jin-Ho
PMID: 21889136
Journal: Biochem Biophys Res Commun. 2012 Jun 22;423(1):38-44.
Title: Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level.
Author: Kwon, Oh-Hyung|Kang, Tae-Wook|Kim, Jeong-Hwan|Kim, Mirang|Noh, Seung-Moo|Song, Kyu-Sang|Yoo, Hyang-Sook|Kim, Woo-Ho|Xie, Zhi|Pocalyko, David|Kim, Seon-Young|Kim, Yong Sung
PMID: 22627140
Journal: World J Gastroenterol. 2012 Aug 14;18(30):4037-43.
Title: Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer.
Author: Lim, Jae Yun|Yoon, Sun Och|Seol, So Young|Hong, Soon Won|Kim, Jong Won|Choi, Seung Ho|Cho, Jae Yong
PMID: 22912555
Journal: World J Gastroenterol. 2013 Jun 7;19(21):3226-40.
Title: Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins.
Author: Wang, Yu-Gang|Wang, Na|Li, Guang-Ming|Fang, Wen-Li|Wei, Jue|Ma, Jia-Li|Wang, Ting|Shi, Min
PMID: 23745024
Journal: PLoS One. 2013 Jun 28;8(6):e67542.
Title: Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells.
Author: Wang, Le-Yi|Liu, Yun-Peng|Chen, Li-Gang|Chen, Yan-Ling|Tan, Li|Liu, Jing-Jing|Jazag, Amarsanaa|Ren, Jian-Lin|Guleng, Bayasi
PMID: 23840737
Journal: Int J Clin Exp Med. 2015 Feb 15;8(2):2423-8. eCollection 2015.
Title: Inhibition of glucose-transporter 1 (GLUT-1) expression reversed Warburg effect in gastric cancer cell MKN45.
Author: Zhang, Tian-Biao|Zhao, Ying|Tong, Zhao-Xue|Guan, Yi-Fu
PMID: 25932183
Journal: Am J Cancer Res. 2015 Mar 15;5(4):1423-34. eCollection 2015.
Title: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling.
Author: Chen, Guangxia|Feng, Wan|Zhang, Shu|Bian, Kangqi|Yang, Yan|Fang, Cheng|Chen, Min|Yang, Jun|Zou, Xiaoping
PMID: 26101707
Journal: Int J Clin Exp Pathol. 2015 Aug 1;8(8):9264-71. eCollection 2015.
Title: Overexpression of metabolic markers HK1 and PKM2 contributes to lymphatic metastasis and adverse prognosis in Chinese gastric cancer.
Author: Gao, Yunshu|Xu, Dongyun|Yu, Guanzhen|Liang, Jun
PMID: 26464675
Journal: Onco Targets Ther. 2016 Jul 14;9:4277-88.
Title: Pyruvate kinase M2 overexpression and poor prognosis in solid tumors of digestive system: evidence from 16 cohort studies.
Author: Wu, Jiayuan|Hu, Liren|Chen, Manyu|Cao, Wenjun|Chen, Haicong|He, Taiping
PMID: 27478385
Journal: Cancer Sci. 2016 Dec;107(12):1767-1775.
Title: MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1.
Author: Sugiyama, Taro|Taniguchi, Kohei|Matsuhashi, Nobuhisa|Tajirika, Toshihiro|Futamura, Manabu|Takai, Tomoaki|Akao, Yukihiro|Yoshida, Kazuhiro
PMID: 27696637
Journal: Oncotarget. 2016 Feb 2;7(5):5972-84.
Title: MiR-let-7a inhibits cell proliferation, migration, and invasion by down-regulating PKM2 in gastric cancer.
Author: Tang, Ran|Yang, Chao|Ma, Xiang|Wang, Younan|Luo, Dakui|Huang, Chi|Xu, Zekuan|Liu, Ping|Yang, Li
PMID: 26745603
Journal: Oncotarget. 2017 Jan 3;8(1):1628-1640.
Title: Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis.
Author: Zhu, Haiyan|Luo, Hui|Zhu, Xuejie|Hu, Xiaoli|Zheng, Lihong|Zhu, Xueqiong
PMID: 27911861
Journal: Cancer Sci. 2017 May;108(5):931-940.
Title: Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
Author: Shiroki, Takeharu|Yokoyama, Misa|Tanuma, Nobuhiro|Maejima, Ryuhei|Tamai, Keiichi|Yamaguchi, Kazunori|Oikawa, Tomoyuki|Noguchi, Tetsuya|Miura, Koh|Fujiya, Tsuneaki|Shima, Hiroshi|Sato, Ikuro|Murata-Kamiya, Naoko|Hatakeyama, Masanori|Iijima, Katsunori|Shimo
PMID: 28235245
Journal: Sci Rep. 2017 Jun 6;7(1):2886.
Title: PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.
Author: Wang, Chao|Jiang, Jinling|Ji, Jun|Cai, Qu|Chen, Xuehua|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 28588255
Journal: Cancer Sci. 2017 Dec;108(12):2462-2469.
Title: Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer.
Author: Kitayama, Kishu|Yashiro, Masakazu|Morisaki, Tamami|Miki, Yuichiro|Okuno, Tomohisa|Kinoshita, Haruhito|Fukuoka, Tatsunari|Kasashima, Hiroaki|Masuda, Go|Hasegawa, Tsuyoshi|Sakurai, Katsunobu|Kubo, Naoshi|Hirakawa, Kosei|Ohira, Masaichi
PMID: 29032577
Journal: Oncol Lett. 2018 Apr;15(4):4358-4364.
Title: LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2.
Author: Lu, Jian|Chen, Min|Gao, Sumeng|Yuan, Jigang|Zhu, Zhu|Zou, Xiaoping
PMID: 29541204
Journal: Cancer Cell Int. 2018 Jul 4;18:92.
Title: rs61991156 in miR-379 is associated with low capability of glycolysis of gastric cancer by enhanced regulation of PKM2.
Author: Cao, Na|Li, Meng|Han, Jun|Wang, Yongren|Wang, Xiaowei
PMID: 29997453
Journal: Cancer Manag Res. 2018 Jul 4;10:1865-1874.
Title: The effect of HIF-1alpha and PKM1 expression on acquisition of chemoresistance.
Author: Okazaki, Mitsuyoshi|Fushida, Sachio|Tsukada, Tomoya|Kinoshita, Jun|Oyama, Katsunobu|Miyashita, Tomoharu|Ninomiya, Itasu|Harada, Shinichi|Ohta, Tetsuo
PMID: 30013393
Journal: Int J Biochem Cell Biol. 2018 Aug 29;104:1-8.
Title: PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma.
Author: Fan, Ping|Wang, Bo|Meng, Zibo|Zhao, Jingyuan|Jin, Xin
PMID: 30172011