Primary Site >> Stomach Cancer
Gene >> PKM
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Ref: Clinical impact of EUS-guided Trucut biopsy results on decision making for patients with gastric subepithelial tumors >/= 2 cm in diameter. PMID: 21889136 |
Ref: Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level. PMID: 22627140 Ref: Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer. PMID: 22912555 |
Ref: Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins. PMID: 23745024 Ref: Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells. PMID: 23840737 |
Ref: Inhibition of glucose-transporter 1 (GLUT-1) expression reversed Warburg effect in gastric cancer cell MKN45. PMID: 25932183 Ref: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling. PMID: 26101707 Ref: Overexpression of metabolic markers HK1 and PKM2 contributes to lymphatic metastasis and adverse prognosis in Chinese gastric cancer. PMID: 26464675 |
Ref: MiR-let-7a inhibits cell proliferation, migration, and invasion by down-regulating PKM2 in gastric cancer. PMID: 26745603 Ref: Pyruvate kinase M2 overexpression and poor prognosis in solid tumors of digestive system: evidence from 16 cohort studies. PMID: 27478385 Ref: MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1. PMID: 27696637 |
Ref: Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis. PMID: 27911861 Ref: Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism. PMID: 28235245 Ref: PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer. PMID: 28588255 Ref: Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer. PMID: 29032577 |
Ref: LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2. PMID: 29541204 Ref: rs61991156 in miR-379 is associated with low capability of glycolysis of gastric cancer by enhanced regulation of PKM2. PMID: 29997453 Ref: The effect of HIF-1alpha and PKM1 expression on acquisition of chemoresistance. PMID: 30013393 Ref: PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma. PMID: 30172011 |