Primary Site >> Colorectal Cancer
Gene >> PIK3R2
| 1. | |||||||||||
| Journal: | J Biol Chem. 1998 Nov 27;273(48):32016-22. | ||||||||||
| Title: | A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon. | ||||||||||
| Author: | Graness, A|Adomeit, A|Heinze, R|Wetzker, R|Liebmann, C | ||||||||||
| PMID: | 9822674 | ||||||||||
| 2. | |||||||||||
| Journal: | Anticancer Res. 1999 Sep-Oct;19(5B):4171-6. | ||||||||||
| Title: | Down regulation of the expression of the p110, p85 and p55 subunits of phosphatidylinositol 3-kinase during colon cancer cell anchorage-independent growth. | ||||||||||
| Author: | Yeates, L C|Gallegos, A|Kozikowski, A P|Powis, G | ||||||||||
| PMID: | 10628371 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2001 May;120(6):1381-92. | ||||||||||
| Title: | Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation. | ||||||||||
| Author: | Wang, Q|Wang, X|Hernandez, A|Kim, S|Evers, B M | ||||||||||
| PMID: | 11313308 | ||||||||||
| 4. | |||||||||||
| Journal: | J Nutr. 2003 Aug;133(8):2675-81. | ||||||||||
| Title: | Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. | ||||||||||
| Author: | Kim, Eun Ji|Kang, Il-Jun|Cho, Han Jin|Kim, Woo Kyoung|Ha, Yeong-Lae|Park, Jung Han Yoon | ||||||||||
| PMID: | 12888657 | ||||||||||
| 5. | |||||||||||
| Journal: | J Med Food. 2005 Winter;8(4):431-8. | ||||||||||
| Title: | Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein. | ||||||||||
| Author: | Kim, Eun Ji|Shin, Hyun-Kyung|Park, Jung Han Yoon | ||||||||||
| PMID: | 16379552 | ||||||||||
| 6. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2006 Feb;132(2):113-20. Epub 2005 Oct 28. | ||||||||||
| Title: | Dominant expression of 85-kDa form of cortactin in colorectal cancer. | ||||||||||
| Author: | Zhang, Lian-Hai|Tian, Bo|Diao, Li-Rong|Xiong, Yong-Yan|Tian, Su-Fang|Zhang, Bian-Hong|Li, Wen-Mei|Ren, Hui|Li, Yan|Ji, Jia-Fu | ||||||||||
| PMID: | 16261345 | ||||||||||
| 7. | |||||||||||
| Journal: | World J Gastroenterol. 2006 Mar 28;12(12):1859-64. | ||||||||||
| Title: | Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells. | ||||||||||
| Author: | Ferrand, Audrey|Kowalski-Chauvel, Aline|Pannequin, Julie|Bertrand, Claudine|Fourmy, Daniel|Dufresne, Marlene|Seva, Catherine | ||||||||||
| PMID: | 16609991 | ||||||||||
| 8. | |||||||||||
| Journal: | FASEB J. 2007 Jun;21(8):1730-41. Epub 2007 Feb 22. | ||||||||||
| Title: | FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. | ||||||||||
| Author: | Thamilselvan, Vijayalakshmi|Craig, David H|Basson, Marc D | ||||||||||
| PMID: | 17317726 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Lett. 2007 Dec 8;258(1):144-53. Epub 2007 Oct 17. | ||||||||||
| Title: | Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line. | ||||||||||
| Author: | Engelbrecht, A-M|Mattheyse, M|Ellis, B|Loos, B|Thomas, M|Smith, R|Peters, S|Smith, C|Myburgh, K | ||||||||||
| PMID: | 17923279 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Carcinog. 2008 Apr;47(4):264-74. | ||||||||||
| Title: | Retinol decreases phosphatidylinositol 3-kinase activity in colon cancer cells. | ||||||||||
| Author: | Park, Eun Young|Wilder, Erik T|Chipuk, Joseph E|Lane, Michelle A | ||||||||||
| PMID: | 17918208 | ||||||||||
| 11. | |||||||||||
| Journal: | Digestion. 2009;80(4):215-25. | ||||||||||
| Title: | Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer. | ||||||||||
| Author: | Yonezawa, Masaoki|Wada, Ken|Tatsuguchi, Atsushi|Akamatsu, Tomonori|Gudis, Katya|Seo, Tsuguhiko|Mitsui, Keigo|Nagata, Kazuhiro|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu | ||||||||||
| PMID: | 19797898 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncogene. 2012 Jul 5;31(27):3277-86. | ||||||||||
| Title: | p37delta is a new isoform of PI3K p110delta that increases cell proliferation and is overexpressed in tumors. | ||||||||||
| Author: | Fransson, S|Uv, A|Eriksson, H|Andersson, M K|Wettergren, Y|Bergo, M|Ejeskar, K | ||||||||||
| PMID: | 22020336 | ||||||||||
| 13. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11318-23. | ||||||||||
| Title: | p85beta phosphoinositide 3-kinase subunit regulates tumor progression. | ||||||||||
| Author: | Cortes, Isabel|Sanchez-Ruiz, Jesus|Zuluaga, Susana|Calvanese, Vincenzo|Marques, Miriam|Hernandez, Carmen|Rivera, Teresa|Kremer, Leonor|Gonzalez-Garcia, Ana|Carrera, Ana C | ||||||||||
| PMID: | 22733740 | ||||||||||
| 14. | |||||||||||
| Journal: | BMC Gastroenterol. 2012 Jan 23;12:9. | ||||||||||
| Title: | Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells. | ||||||||||
| Author: | Lim, Do Young|Cho, Han Jin|Kim, Jongdai|Nho, Chu Won|Lee, Ki Won|Park, Jung Han Yoon | ||||||||||
| PMID: | 22269172 | ||||||||||
| 15. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2013 May 17;434(4):760-6. | ||||||||||
| Title: | PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells. | ||||||||||
| Author: | Liu, Jingyi|Liao, Yueling|Ma, Kewei|Wang, Yonglu|Zhang, Guoxiang|Yang, Rongcun|Deng, Jiong | ||||||||||
| PMID: | 23583404 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Oncol. 2013 Aug;43(2):629-37. | ||||||||||
| Title: | Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling. | ||||||||||
| Author: | Chen, Hui-Jye|Lin, Chung-Ming|Lee, Chao-Ying|Shih, Nai-Chen|Amagaya, Sakae|Lin, Yung-Chang|Yang, Jai-Sing | ||||||||||
| PMID: | 23754208 | ||||||||||
| 17. | |||||||||||
| Journal: | J Cancer Prev. 2014 Sep;19(3):161-9. | ||||||||||
| Title: | Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells. | ||||||||||
| Author: | Lee, Hyun Sook|Cho, Han Jin|Kwon, Gyoo Taik|Park, Jung Han Yoon | ||||||||||
| PMID: | 25337585 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Rep. 2016 Jan;35(1):205-10. | ||||||||||
| Title: | Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. | ||||||||||
| Author: | Xiang, Tao|Fei, Rushan|Wang, Zhe|Shen, Zhonglei|Qian, Jing|Chen, Wenbin | ||||||||||
| PMID: | 26530054 | ||||||||||
| 19. | |||||||||||
| Journal: | Tumour Biol. 2016 Oct;37(10):14089-14101. | ||||||||||
| Title: | Experimental verification of a predicted novel microRNA located in human PIK3CA gene with a potential oncogenic function in colorectal cancer. | ||||||||||
| Author: | Saleh, Ali Jason|Soltani, Bahram M|Dokanehiifard, Sadat|Medlej, Abdallah|Tavalaei, Mahmoud|Mowla, Seyed Javad | ||||||||||
| PMID: | 27511117 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncol Lett. 2016 Oct;12(4):2329-2336. | ||||||||||
| Title: | Mechanism analysis of colorectal cancer according to the microRNA expression profile. | ||||||||||
| Author: | Li, Hong|Zhang, Huichao|Lu, Gang|Li, Qingjing|Gu, Jifeng|Song, Yuan|Gao, Shejun|Ding, Yawen | ||||||||||
| PMID: | 27698796 | ||||||||||
| 21. | |||||||||||
| Journal: | J Med Genet. 2017 Aug;54(8):567-571. | ||||||||||
| Title: | Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab. | ||||||||||
| Author: | Madi, Ayman|Fisher, David|Maughan, Timothy S|Colley, James P|Meade, Angela M|Tejpar, Sabine|Van den Bosch, Ben|Maynard, Julie|Humphreys, Vikki|Wasan, Harpreet|Adams, Richard A|Idziaszczyk, Shelley|Harris, Rebecca|Kaplan, Richard S|Cheadle, Jeremy P | ||||||||||
| PMID: | 28283541 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncol Rep. 2017 Nov;38(5):2619-2628. | ||||||||||
| Title: | alpha7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway. | ||||||||||
| Author: | Fei, Rushan|Zhang, Yuanwei|Wang, Saisai|Xiang, Tao|Chen, Wenbin | ||||||||||
| PMID: | 28901507 | ||||||||||
| 23. | |||||||||||
| Journal: | Bull Cancer. 2018 Oct 8. pii: S0007-4551(18)30275-3. | ||||||||||
| Title: | PTBP1 promotes tumorigenesis by regulating apoptosis and cell cycle in colon cancer. | ||||||||||
| Author: | Li, Xiaona|Han, Fei|Liu, Wenbin|Shi, Xiaoyan | ||||||||||
| PMID: | 30309622 | ||||||||||