Primary Site >> Colorectal Cancer
Gene >> PIK3R2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon. PMID: 9822674 |
Ref: Down regulation of the expression of the p110, p85 and p55 subunits of phosphatidylinositol 3-kinase during colon cancer cell anchorage-independent growth. PMID: 10628371 |
Ref: Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation. PMID: 11313308 |
Ref: Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. PMID: 12888657 |
Ref: Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein. PMID: 16379552 |
Ref: Dominant expression of 85-kDa form of cortactin in colorectal cancer. PMID: 16261345 Ref: Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells. PMID: 16609991 |
Ref: FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. PMID: 17317726 Ref: Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line. PMID: 17923279 |
Ref: Retinol decreases phosphatidylinositol 3-kinase activity in colon cancer cells. PMID: 17918208 |
Ref: Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer. PMID: 19797898 |
Ref: p37delta is a new isoform of PI3K p110delta that increases cell proliferation and is overexpressed in tumors. PMID: 22020336 Ref: Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells. PMID: 22269172 Ref: p85beta phosphoinositide 3-kinase subunit regulates tumor progression. PMID: 22733740 |
Ref: PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells. PMID: 23583404 Ref: Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling. PMID: 23754208 |
Ref: Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells. PMID: 25337585 |
Ref: Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. PMID: 26530054 Ref: Experimental verification of a predicted novel microRNA located in human PIK3CA gene with a potential oncogenic function in colorectal cancer. PMID: 27511117 Ref: Mechanism analysis of colorectal cancer according to the microRNA expression profile. PMID: 27698796 |
Ref: Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab. PMID: 28283541 Ref: alpha7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway. PMID: 28901507 |
Ref: PTBP1 promotes tumorigenesis by regulating apoptosis and cell cycle in colon cancer. PMID: 30309622 |