Primary Site >> Colorectal Cancer
Gene >> PIK3R1
| 1. | |||||||||||
| Journal: | J Biol Chem. 1995 Jun 30;270(26):15591-7. | ||||||||||
| Title: | Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha. | ||||||||||
| Author: | Stover, D R|Becker, M|Liebetanz, J|Lydon, N B | ||||||||||
| PMID: | 7797556 | ||||||||||
| 2. | |||||||||||
| Journal: | Immunol Cell Biol. 1995 Apr;73(2):134-9. | ||||||||||
| Title: | Production of monoclonal antibodies specific to the carboxyl terminal region of the 85 kDa subunit of phosphatidylinositol 3-kinase: use of the antibodies in recognition of mutant p85. | ||||||||||
| Author: | Daduang, S|Nagata, S|Matsuda, M|Yamori, T|Onodera, K|Fukui, Y | ||||||||||
| PMID: | 7541019 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2000 Oct 19;19(44):5083-90. | ||||||||||
| Title: | A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells. | ||||||||||
| Author: | Benistant, C|Chapuis, H|Roche, S | ||||||||||
| PMID: | 11042696 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2001 Oct 15;61(20):7426-9. | ||||||||||
| Title: | The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors. | ||||||||||
| Author: | Philp, A J|Campbell, I G|Leet, C|Vincan, E|Rockman, S P|Whitehead, R H|Thomas, R J|Phillips, W A | ||||||||||
| PMID: | 11606375 | ||||||||||
| 5. | |||||||||||
| Journal: | Carcinogenesis. 2004 Feb;25(2):241-8. | ||||||||||
| Title: | Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma. | ||||||||||
| Author: | Khaleghpour, Kianoush|Li, Yang|Banville, Denis|Yu, Zhenbao|Shen, Shi-Hsiang | ||||||||||
| PMID: | 14578160 | ||||||||||
| 6. | |||||||||||
| Journal: | World J Gastroenterol. 2005 Sep 7;11(33):5142-50. | ||||||||||
| Title: | Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells. | ||||||||||
| Author: | Cho, Han Jin|Kim, Woo Kyoung|Jung, Jae In|Kim, Eun Ji|Lim, Soon Sung|Kwon, Dae Young|Park, Jung Han Yoon | ||||||||||
| PMID: | 16127743 | ||||||||||
| 7. | |||||||||||
| Journal: | FASEB J. 2007 Jun;21(8):1730-41. Epub 2007 Feb 22. | ||||||||||
| Title: | FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. | ||||||||||
| Author: | Thamilselvan, Vijayalakshmi|Craig, David H|Basson, Marc D | ||||||||||
| PMID: | 17317726 | ||||||||||
| 8. | |||||||||||
| Journal: | Genome Biol. 2007;8(7):R131. | ||||||||||
| Title: | Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. | ||||||||||
| Author: | Kaiser, Sergio|Park, Young-Kyu|Franklin, Jeffrey L|Halberg, Richard B|Yu, Ming|Jessen, Walter J|Freudenberg, Johannes|Chen, Xiaodi|Haigis, Kevin|Jegga, Anil G|Kong, Sue|Sakthivel, Bhuvaneswari|Xu, Huan|Reichling, Timothy|Azhar, Mohammad|Boivin, Gregory P| | ||||||||||
| PMID: | 17615082 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Feb 1;14(3):633-7. | ||||||||||
| Title: | Association between phosphatidylinositol 3-kinase regulatory subunit p85alpha Met326Ile genetic polymorphism and colon cancer risk. | ||||||||||
| Author: | Li, Li|Plummer, Sarah J|Thompson, Cheryl L|Tucker, Thomas C|Casey, Graham | ||||||||||
| PMID: | 18245521 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Carcinog. 2008 Jan;47(1):9-21. | ||||||||||
| Title: | Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion. | ||||||||||
| Author: | Fenton, Jenifer I|Lavigne, Jackie A|Perkins, Susan N|Liu, Huaitian|Chandramouli, Gadisetti V R|Shih, Joanna H|Hord, Norman G|Hursting, Stephen D | ||||||||||
| PMID: | 17620308 | ||||||||||
| 11. | |||||||||||
| Journal: | Digestion. 2009;80(4):215-25. | ||||||||||
| Title: | Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer. | ||||||||||
| Author: | Yonezawa, Masaoki|Wada, Ken|Tatsuguchi, Atsushi|Akamatsu, Tomonori|Gudis, Katya|Seo, Tsuguhiko|Mitsui, Keigo|Nagata, Kazuhiro|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu | ||||||||||
| PMID: | 19797898 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Cell. 2009 Dec 8;16(6):463-74. | ||||||||||
| Title: | Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. | ||||||||||
| Author: | Jaiswal, Bijay S|Janakiraman, Vasantharajan|Kljavin, Noelyn M|Chaudhuri, Subhra|Stern, Howard M|Wang, Weiru|Kan, Zhengyan|Dbouk, Hashem A|Peters, Brock A|Waring, Paul|Dela Vega, Trisha|Kenski, Denise M|Bowman, Krista K|Lorenzo, Maria|Li, Hong|Wu, Jianshen | ||||||||||
| PMID: | 19962665 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):781-7. | ||||||||||
| Title: | Analysis of expression profile of gene encoding proteins of signal cascades activated by insulin-like growth factors in colorectal cancer. | ||||||||||
| Author: | Nowakowska-Zajdel, E|Mazurek, U|Ziolko, E|Niedworok, E|Fatyga, E|Kokot, T|Muc-Wierzgon, Malgorzata | ||||||||||
| PMID: | 21978709 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2012 Jun;11(2):143-50. | ||||||||||
| Title: | PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer. | ||||||||||
| Author: | Sood, Arjun|McClain, Danielle|Maitra, Radhashree|Basu-Mallick, Atrayee|Seetharam, Raviraja|Kaubisch, Andreas|Rajdev, Lakshmi|Mariadason, John M|Tanaka, Kathryn|Goel, Sanjay | ||||||||||
| PMID: | 22285706 | ||||||||||
| 15. | |||||||||||
| Journal: | Clin Cancer Res. 2012 May 1;18(9):2704-14. | ||||||||||
| Title: | Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib. | ||||||||||
| Author: | Arcaroli, John J|Quackenbush, Kevin S|Powell, Rebecca W|Pitts, Todd M|Spreafico, Anna|Varella-Garcia, Marileila|Bemis, Lynne|Tan, Aik Choon|Reinemann, Jaclyn M|Touban, Basel M|Dasari, Arvind|Eckhardt, S Gail|Messersmith, Wells A | ||||||||||
| PMID: | 22553375 | ||||||||||
| 16. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2013 May 17;434(4):760-6. | ||||||||||
| Title: | PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells. | ||||||||||
| Author: | Liu, Jingyi|Liao, Yueling|Ma, Kewei|Wang, Yonglu|Zhang, Guoxiang|Yang, Rongcun|Deng, Jiong | ||||||||||
| PMID: | 23583404 | ||||||||||
| 17. | |||||||||||
| Journal: | Int J Oncol. 2013 Aug;43(2):629-37. | ||||||||||
| Title: | Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling. | ||||||||||
| Author: | Chen, Hui-Jye|Lin, Chung-Ming|Lee, Chao-Ying|Shih, Nai-Chen|Amagaya, Sakae|Lin, Yung-Chang|Yang, Jai-Sing | ||||||||||
| PMID: | 23754208 | ||||||||||
| 18. | |||||||||||
| Journal: | Ann Surg Oncol. 2014 Aug;21(8):2642-9. | ||||||||||
| Title: | The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study. | ||||||||||
| Author: | Abdul-Jalil, Khairun I|Sheehan, Katherine M|Toomey, Sinead|Schmid, Jasmin|Prehn, Jochen|O'Grady, Anthony|Cummins, Robert|O'Neill, Brian|McNamara, Deborah A|Deasy, Joseph|Breathnach, Oscar|Grogan, Liam|Rogers, Ailin|Doherty, Glen|Winter, Des|Ryan, John|El- | ||||||||||
| PMID: | 24700299 | ||||||||||
| 19. | |||||||||||
| Journal: | Hepatogastroenterology. 2014 Nov-Dec;61(136):2215-8. | ||||||||||
| Title: | Comparison analysis in synchronous and metachronous metastatic colorectal cancer based on microarray expression profile. | ||||||||||
| Author: | Wang, Da-dong|Xu, Yong|Tu, Yu-liang|Tan, Xiang-long|Zhu, Zi-man|Han, Ming-ming|Dou, Chun-qing|Zeng, Jian-ping|Tan, Jing-wang|Du, Jun-dong|Jiao, Hua-bou|Cai, Shou-wang | ||||||||||
| PMID: | 25699354 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Cell. 2014 Oct 13;26(4):445-7. | ||||||||||
| Title: | The double life of p85. | ||||||||||
| Author: | Costa, Carlotta|Engelman, Jeffrey A | ||||||||||
| PMID: | 25314071 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Lett. 2015 Apr 1;359(1):47-56. | ||||||||||
| Title: | Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer. | ||||||||||
| Author: | Qazi, Asif Khurshid|Hussain, Aashiq|Khan, Saima|Aga, Mushtaq A|Behl, Akanksha|Ali, Shakir|Singh, Shashank Kumar|Taneja, Subhash Chandra|Shah, Bhahwal Ali|Saxena, Ajit Kumar|Mondhe, Dilip Manikrao|Hamid, Abid | ||||||||||
| PMID: | 25554016 | ||||||||||
| 22. | |||||||||||
| Journal: | Onco Targets Ther. 2015 Jul 8;8:1691-9. | ||||||||||
| Title: | Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. | ||||||||||
| Author: | Tian, XiaoQing|Sun, DanFeng|Zhao, ShuLiang|Xiong, Hua|Fang, JingYuan | ||||||||||
| PMID: | 26185457 | ||||||||||
| 23. | |||||||||||
| Journal: | PLoS One. 2015 Oct 15;10(10):e0140479. | ||||||||||
| Title: | Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092. | ||||||||||
| Author: | Yu, Yi|Savage, Ronald E|Eathiraj, Sudharshan|Meade, Justin|Wick, Michael J|Hall, Terence|Abbadessa, Giovanni|Schwartz, Brian | ||||||||||
| PMID: | 26469692 | ||||||||||
| 24. | |||||||||||
| Journal: | Mol Cancer. 2015 Oct 24;14:182. | ||||||||||
| Title: | Activin and TGFbeta use diverging mitogenic signaling in advanced colon cancer. | ||||||||||
| Author: | Bauer, Jessica|Ozden, Ozkan|Akagi, Naomi|Carroll, Timothy|Principe, Daniel R|Staudacher, Jonas J|Spehlmann, Martina E|Eckmann, Lars|Grippo, Paul J|Jung, Barbara | ||||||||||
| PMID: | 26497569 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncol Rep. 2016 Jan;35(1):205-10. | ||||||||||
| Title: | Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. | ||||||||||
| Author: | Xiang, Tao|Fei, Rushan|Wang, Zhe|Shen, Zhonglei|Qian, Jing|Chen, Wenbin | ||||||||||
| PMID: | 26530054 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2016 Feb 10;11(2):e0148730. | ||||||||||
| Title: | Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K. | ||||||||||
| Author: | Yueh, Alexander E|Payne, Susan N|Leystra, Alyssa A|Van De Hey, Dana R|Foley, Tyler M|Pasch, Cheri A|Clipson, Linda|Matkowskyj, Kristina A|Deming, Dustin A | ||||||||||
| PMID: | 26863299 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2016 Apr 20;11(4):e0153681. | ||||||||||
| Title: | Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression. | ||||||||||
| Author: | Schulten, Hans-Juergen|Hussein, Deema|Al-Adwani, Fatima|Karim, Sajjad|Al-Maghrabi, Jaudah|Al-Sharif, Mona|Jamal, Awatif|Al-Ghamdi, Fahad|Baeesa, Saleh S|Bangash, Mohammed|Chaudhary, Adeel|Al-Qahtani, Mohammed | ||||||||||
| PMID: | 27096627 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 27;8(26):42487-42494. | ||||||||||
| Title: | Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma. | ||||||||||
| Author: | Vakiani, Efsevia|Shah, Ronak H|Berger, Michael F|Makohon-Moore, Alvin P|Reiter, Johannes G|Ostrovnaya, Irina|Attiyeh, Marc A|Cercek, Andrea|Shia, Jinru|Iacobuzio-Donahue, Christine A|Solit, David B|Weiser, Martin R | ||||||||||
| PMID: | 28476018 | ||||||||||
| 29. | |||||||||||
| Journal: | BMC Genomics. 2017 May 30;18(1):421. | ||||||||||
| Title: | Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort. | ||||||||||
| Author: | Cong, Wang|Meng, Xianglian|Li, Jin|Zhang, Qiushi|Chen, Feng|Liu, Wenjie|Wang, Ying|Cheng, Sipu|Yao, Xiaohui|Yan, Jingwen|Kim, Sungeun|Saykin, Andrew J|Liang, Hong|Shen, Li | ||||||||||
| PMID: | 28558704 | ||||||||||
| 30. | |||||||||||
| Journal: | Tumour Biol. 2017 Jul;39(7):1010428317714899. | ||||||||||
| Title: | Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing. | ||||||||||
| Author: | Liu, Jixi|Liu, Fang|Li, Xiaoou|Song, Xin|Zhou, Lei|Jie, Jianzheng | ||||||||||
| PMID: | 28714374 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncol Rep. 2017 Nov;38(5):2619-2628. | ||||||||||
| Title: | alpha7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway. | ||||||||||
| Author: | Fei, Rushan|Zhang, Yuanwei|Wang, Saisai|Xiang, Tao|Chen, Wenbin | ||||||||||
| PMID: | 28901507 | ||||||||||
| 32. | |||||||||||
| Journal: | Tumour Biol. 2017 Sep;39(9):1010428317724517. | ||||||||||
| Title: | EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features. | ||||||||||
| Author: | Alvarez, Karin|Orellana, Paulina|Villarroel, Cynthia|Contreras, Luis|Kawachi, Hiroshi|Kobayashi, Maki|Wielandt, Ana Maria|De la Fuente, Marjorie|Trivino, Juan Carlos|Kronberg, Udo|Carvallo, Pilar|Lopez-Kostner, Francisco | ||||||||||
| PMID: | 28936923 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Cancer Ther. 2018 May;17(5):977-987. | ||||||||||
| Title: | A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-kappaB Signaling in KRAS-Mutant Colon Cancer Cells. | ||||||||||
| Author: | Inoue, Akira|Mizushima, Tsunekazu|Wu, Xin|Okuzaki, Daisuke|Kambara, Nanami|Ishikawa, Sho|Wang, Jiaqi|Qian, Yamin|Hirose, Haruka|Yokoyama, Yuhki|Ikeshima, Ryo|Hiraki, Masayuki|Miyoshi, Norikatsu|Takahashi, Hidekazu|Haraguchi, Naotsugu|Hata, Taishi|Matsuda, | ||||||||||
| PMID: | 29545333 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Mol Med. 2018 Jul;42(1):368-380. | ||||||||||
| Title: | Inflammatory genes are novel prognostic biomarkers for colorectal cancer. | ||||||||||
| Author: | Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo | ||||||||||
| PMID: | 29693170 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncol Lett. 2018 May;15(5):7243-7248. | ||||||||||
| Title: | miR-486-5p regulates the migration and invasion of colorectal cancer cells through targeting PIK3R1. | ||||||||||
| Author: | Zhang, Yuhao|Fu, Jun|Zhang, Zhijin|Qin, Huanlong | ||||||||||
| PMID: | 29725442 | ||||||||||