Primary Site >> Stomach Cancer

Gene >> PIK3CD

1.
Journal: Int J Cancer. 2005 Nov 10;117(3):376-80.
Title: Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer.
Author: Oki, Eiji|Baba, Hideo|Tokunaga, Eriko|Nakamura, Toshihiko|Ueda, Naoyuki|Futatsugi, Motonori|Mashino, Kohjiro|Yamamoto, Manabu|Ikebe, Masahiko|Kakeji, Yoshihiro|Maehara, Yoshihiko
PMID: 15900596
2.
Journal: Cancer Biol Ther. 2006 Apr;5(4):371-4. Epub 2006 Apr 30.
Title: How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions.
Author: Vogiatzi, Paraskevi|De Falco, Giulia|Claudio, Pier Paolo|Giordano, Antonio
PMID: 16627973
3.
Journal: Cancer Res. 2006 May 15;66(10):4991-5.
Title: Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1.
Author: Bae, In Hwa|Park, Myung-Jin|Yoon, Sung Hwan|Kang, Sung Wook|Lee, Seung-Sook|Choi, Kyung-Mi|Um, Hong-Duck
PMID: 16707418
4.
Journal: Int J Oncol. 2006 Jul;29(1):163-8.
Title: FGF signaling network in the gastrointestinal tract (review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16773196
5.
Journal: Int J Oncol. 2006 Sep;29(3):549-55.
Title: CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway.
Author: Ardyanto, Tonang Dwi|Osaki, Mitsuhiko|Tokuyasu, Naruo|Nagahama, Yumi|Ito, Hisao
PMID: 16865270
6.
Journal: Br J Cancer. 2006 Dec 4;95(11):1504-13. Epub 2006 Nov 7.
Title: Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis.
Author: Yokoyama, H|Ikehara, Y|Kodera, Y|Ikehara, S|Yatabe, Y|Mochizuki, Y|Koike, M|Fujiwara, M|Nakao, A|Tatematsu, M|Nakanishi, H
PMID: 17088902
7.
Journal: World J Gastroenterol. 2007 Jul 7;13(25):3517-22.
Title: RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway.
Author: Sun, Hua-Wen|Tong, Shi-Lun|He, Jie|Wang, Qi|Zou, Li|Ma, Shu-Jing|Tan, Hai-Yan|Luo, Jian-Fei|Wu, Hong-Xue
PMID: 17659701
8.
Journal: Int J Cancer. 2007 Dec 1;121(11):2547-55.
Title: 2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer.
Author: Lin, Heng-Liang|Yang, Muh-Hwa|Wu, Chew-Wun|Chen, Po-Min|Yang, Yi-Ping|Chu, Yue-Ru|Kao, Chung-Lan|Ku, Hung-Hai|Lo, Jen-Fan|Liou, Jing-Ping|Chi, Chin-Wen|Chiou, Shih-Hwa
PMID: 17680560
9.
Journal: Mol Cancer Res. 2007 Nov;5(11):1111-23.
Title: Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2.
Author: Lin, Been-Ren|Chang, Cheng-Chi|Chen, Li-Ro|Wu, Ming-Hsun|Wang, Ming-Yang|Kuo, I-Hsin|Chu, Chia-Yu|Chang, King-Jen|Lee, Po-Huang|Chen, Wei-Jao|Kuo, Min-Liang|Lin, Ming-Tsan
PMID: 18025257
10.
Journal: Growth Factors. 2007 Dec;25(6):373-81.
Title: Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin.
Author: Pazos, Yolanda|Alvarez, Carlos J P|Camina, Jesus P|Casanueva, Felipe F
PMID: 18365868
11.
Journal: Electrophoresis. 2008 Aug;29(15):3192-200.
Title: Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway.
Author: Fukagawa, Yuki|Nishikawa, Jun|Kuramitsu, Yasuhiro|Iwakiri, Dai|Takada, Kenzo|Imai, Shousuke|Satake, Masaaki|Okamoto, Takeshi|Fujimoto, Masanori|Okita, Kiwamu|Nakamura, Kazuyuki|Sakaida, Isao
PMID: 18604870
12.
Journal: Biol Chem. 2008 Jun;389(6):757-64.
Title: Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells.
Author: Henkhaus, Rebecca S|Gerner, Eugene W|Ignatenko, Natalia A
PMID: 18627290
13.
Journal: Mol Cancer Ther. 2008 Nov;7(11):3499-508.
Title: HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.
Author: Bachleitner-Hofmann, Thomas|Sun, Mark Y|Chen, Chin-Tung|Tang, Laura|Song, Lin|Zeng, Zhaoshi|Shah, Manish|Christensen, James G|Rosen, Neal|Solit, David B|Weiser, Martin R
PMID: 18974395
14.
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Jul;30(7):494-7.
Title: [Impact of PI3K /Akt /mdm2 signaling pathway on the sensitivity of gastric cancer cell line SGC7901 to doxorubicin].
Author: Ai, Yao-Wei|Yu, Hong-Gang|Yu, Jie-Ping|Yang, Yan|Li, Huan|Hu, Xiao-Wen|Luo, He-Sheng
PMID: 19062713
15.
Journal: J Gastroenterol Hepatol. 2009 Mar;24(3):480-7.
Title: Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling.
Author: Kim, Nayoung|Kim, Chung Hyun|Ahn, Dong-Won|Lee, Kyoung Soo|Cho, Soo-Jeong|Park, Ji Hyun|Lee, Mi Kyoung|Kim, Joo Sung|Jung, Hyun Chae|Song, In Sung
PMID: 18823436
16.
Journal: FEBS J. 2009 Feb;276(3):685-94.
Title: Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.
Author: Liang, Jie|Ge, Fulin|Guo, Changcun|Luo, Guanhong|Wang, Xin|Han, Guohong|Zhang, Dexin|Wang, Jianhong|Li, Kai|Pan, Yanglin|Yao, Liping|Yin, Zhanxin|Guo, Xuegang|Wu, Kaichun|Ding, Jie|Fan, Daiming
PMID: 19143835
17.
Journal: Drug Resist Updat. 2009 Jun;12(3):55-64.
Title: Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Author: Qiao, Liang|Wong, Benjamin C Y
PMID: 19278896
18.
Journal: World J Gastroenterol. 2009 Jun 21;15(23):2870-7.
Title: Alisol B acetate induces apoptosis of SGC7901 cells via mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways.
Author: Xu, Yong-Hong|Zhao, Li-Jie|Li, Yan
PMID: 19533808
19.
Journal: Mol Cancer Ther. 2009 Sep;8(9):2526-36.
Title: Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells.
Author: Yoon, Young-Kwang|Kim, Hwang-Phill|Han, Sae-Won|Hur, Hyung-Seok|Oh, Do Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 19755509
20.
Journal: World J Gastroenterol. 2009 Nov 28;15(44):5541-8.
Title: Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway.
Author: Li, Guo-Qing|Xie, Juan|Lei, Xiao-Yong|Zhang, Li
PMID: 19938192
21.
Journal: Exp Cell Res. 2010 Jan 1;316(1):24-37.
Title: BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway.
Author: Kang, Myoung Hee|Kim, Jun Suk|Seo, Ji Eun|Oh, Sang Cheul|Yoo, Young A
PMID: 19835871
22.
Journal: Oncol Rep. 2010 Jun;23(6):1735-45.
Title: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines.
Author: Luo, Hui-Yan|Wei, Wei|Shi, Yan-Xia|Chen, Xiao-Qin|Li, Yu-Hong|Wang, Feng|Qiu, Miao-Zhen|Li, Fang-Hua|Yan, Shu-Li|Zeng, Mu-Sheng|Huang, Peng|Xu, Rui-Hua
PMID: 20428833
23.
Journal: Mol Diagn Ther. 2010 Jun 1;14(3):155-61.
Title: Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway.
Author: Wang, Wei-Qiang|Zhang, Hao|Wang, Hong-Bin|Sun, Yong-Gang|Peng, Zhi-Hong|Zhou, Gang|Yang, Shi-Ming|Wang, Rong-Quan|Fang, Dian-Chun
PMID: 20560677
24.
Journal: Cancer Invest. 2010 Dec;28(10):1038-47.
Title: The sequence-dependent cytotoxic effect of trastuzumab in combination with 5-Fluorouracil or cisplatin on gastric cancer cell lines.
Author: Li, Xiao-Ling|Yi, Shao-Qiong|Xu, Jian-Ming|Zhang, Yang|Yingying-Feng|Chen, Wei|Song, San-Tai
PMID: 20590442
25.
Journal: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2508-16.
Title: Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals.
Author: Ho, Hsieh-Hsun|Chang, Chi-Sen|Ho, Wei-Chi|Liao, Sheng-You|Wu, Cheng-Hsun|Wang, Chau-Jong
PMID: 20600540
26.
Journal: BMC Cancer. 2010 Aug 13;10:425.
Title: LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.
Author: Shin, Jung-Young|Kim, Jeong-Oh|Lee, Suk Kyeong|Chae, Hiun-Suk|Kang, Jin-Hyoung
PMID: 20704765
27.
Journal: Cell Biol Int. 2010 Dec;34(12):1141-5.
Title: Sodium butyrate induces differentiation of gastric cancer cells to intestinal cells via the PTEN/phosphoinositide 3-kinase pathway.
Author: Bai, Zhigang|Zhang, Zhongtao|Ye, Yingjiang|Wang, Shan
PMID: 20718712
28.
Journal: Biomed Pharmacother. 2010 Nov;64(9):600-4.
Title: Blocking of PI3K/AKT induces apoptosis by its effect on NF-kappaB activity in gastric carcinoma cell line SGC7901.
Author: Chao, Xu|Zao, Jiang|Xiao-Yi, Gu|Li-Jun, Meng|Tao, Shi
PMID: 20947290
29.
Journal: Mol Med Rep. 2010 May-Jun;3(3):491-6.
Title: Phosphoinositide 3-kinase/Akt and nuclear factor kappaB pathways are involved in tumor necrosis factor-related apoptosis-inducing ligand resistance in human gastric cancer cells.
Author: Liu, Jing|Qu, Xiujuan|Xu, Ling|Zhang, Ye|Qu, Jinglei|Hou, Kezuo|Liu, Yunpeng
PMID: 21472268
30.
Journal: Dig Dis Sci. 2011 Feb;56(2):323-9.
Title: Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis.
Author: Redlak, Maria J|Miller, Thomas A
PMID: 20585984
31.
Journal: Mol Nutr Food Res. 2011 May;55(5):749-60.
Title: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.
Author: Xing, Xin|Wang, Juan|Xing, Ling Xiao|Li, Yue Hong|Yan, Xia|Zhang, Xiang Hong
PMID: 21287681
32.
Journal: Clin Cancer Res. 2011 Aug 15;17(16):5322-32.
Title: Gastric cancer growth control by BEZ235 in vivo does not correlate with PI3K/mTOR target inhibition but with [18F]FLT uptake.
Author: Fuereder, Thorsten|Wanek, Thomas|Pflegerl, Pamina|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Strommer, Sabine|Kuntner, Claudia|Wrba, Friedrich|Werzowa, Johannes|Hejna, Michael|Muller, Markus|Langer, Oliver|Wacheck, Volker
PMID: 21712451
33.
Journal: J Pathol. 2011 Nov;225(3):438-47.
Title: Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop.
Author: Wu, Yan|Zhao, Qiyi|Peng, Chen|Sun, Lin|Li, Xue-Feng|Kuang, Dong-Ming
PMID: 21826665
34.
Journal: J Exp Clin Cancer Res. 2011 Sep 25;30:86.
Title: Aquaporin-3 positively regulates matrix metalloproteinases via PI3K/AKT signal pathway in human gastric carcinoma SGC7901 cells.
Author: Xu, Hao|Xu, Yong|Zhang, Wenjie|Shen, Lizong|Yang, Li|Xu, Zekuan
PMID: 21943213
35.
Journal: Cancer Res. 2011 Nov 15;71(22):7061-70.
Title: Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer.
Author: Yoo, Young A|Kang, Myoung Hee|Lee, Hyun Joo|Kim, Baek-hui|Park, Jong Kuk|Kim, Hyun Koo|Kim, Jun Suk|Oh, Sang Cheul
PMID: 21975935
36.
Journal: Int J Oncol. 2012 Apr;40(4):1153-61.
Title: Magnolol, a natural compound, induces apoptosis of SGC-7901 human gastric adenocarcinoma cells via the mitochondrial and PI3K/Akt signaling pathways.
Author: Rasul, Azhar|Yu, Bo|Khan, Muhammad|Zhang, Kun|Iqbal, Furhan|Ma, Tonghui|Yang, Hong
PMID: 22139054
37.
Journal: Int J Oncol. 2012 Apr;40(4):1259-66.
Title: NVP-BKM120, a novel PI3K inhibitor, shows synergism with a STAT3 inhibitor in human gastric cancer cells harboring KRAS mutations.
Author: Park, Eunju|Park, Jinah|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22159814
38.
Journal: Immunobiology. 2012 Sep;217(9):926-34.
Title: Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer.
Author: Tseng, Po-Chun|Huang, Wei-Ching|Chen, Chia-Ling|Sheu, Bor-Shyang|Shan, Yan-Shen|Tsai, Cheng-Chieh|Wang, Chi-Yun|Chen, Su-O|Hsieh, Chia-Yuan|Lin, Chiou-Feng
PMID: 22325465
39.
Journal: Oncol Rep. 2012 Sep;28(3):1043-50.
Title: Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Author: Shin, Dong Yeok|Kim, Gi-Young|Kim, Chan Gil|Kim, Wun-Jae|Kang, Ho Sung|Choi, Yung Hyun
PMID: 22710922
40.
Journal: BMC Med Genomics. 2012 Aug 9;5:34.
Title: Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library.
Author: Zhou, Jin|Chen, Geng Bo|Tang, Yew Chung|Sinha, Rohit Anthony|Wu, Yonghui|Yap, Chui Sun|Wang, Guihua|Hu, Junbo|Xia, Xianmin|Tan, Patrick|Goh, Liang Kee|Yen, Paul Michael
PMID: 22876838
41.
Journal: World J Gastroenterol. 2012 Dec 28;18(48):7262-70.
Title: Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45.
Author: Guo, Ling-Yun|Li, Yu-Min|Qiao, Liang|Liu, Tao|Du, Yuan-Yuan|Zhang, Jun-Qiang|He, Wen-Ting|Zhao, Yong-Xun|He, Dong-Qiang
PMID: 23326131
42.
Journal: World J Virol. 2012 Dec 12;1(6):154-61.
Title: Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications.
Author: Chen, Jiezhong
PMID: 24175221
43.
Journal: Mol Biol Rep. 2013 Feb;40(2):999-1008.
Title: Effect of PI3K gene silencing on growth, migration and related proteins expression of CD40 signal-mediated gastric cancer cells.
Author: Li, Rui|Chen, Wei-Chang|Pang, Xue-Qin|Tian, Wen-Yan|Wang, Wei-Peng|Zhang, Xue Guang
PMID: 23114914
44.
Journal: Cell Signal. 2013 Feb;25(2):447-56.
Title: PI3K/Akt-dependent phosphorylation of GSK3beta and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration.
Author: Liu, Jiaojing|Zhang, Yujie|Xu, Rui|Du, Jun|Hu, Zhenzhen|Yang, Ling|Chen, Yongchang|Zhu, Yichao|Gu, Luo
PMID: 23123500
45.
Journal: Biomed Pharmacother. 2013 Feb;67(1):78-87.
Title: Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
Author: Liu, Juan|Xie, Yi-Shan|Wang, Fu-Liang|Zhang, Li-Jun|Zhang, Yan|Luo, He-Sheng
PMID: 23201008
46.
Journal: Mol Cancer Ther. 2013 Feb;12(2):151-61.
Title: VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Author: Hart, Stefan|Novotny-Diermayr, Veronica|Goh, Kee Chuan|Williams, Meredith|Tan, Yong Cheng|Ong, Lai Chun|Cheong, Albert|Ng, Bee Kheng|Amalini, Chithra|Madan, Babita|Nagaraj, Harish|Jayaraman, Ramesh|Pasha, Khalid M|Ethirajulu, Kantharaj|Chng, Wee Joo|Musta
PMID: 23270925
47.
Journal: Cancer Lett. 2013 May 10;332(1):11-8.
Title: Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells.
Author: Xu, Wei|Chen, Guo-Sheng|Shao, Yun|Li, Xiao-Lin|Xu, Hai-Chen|Zhang, Hao|Zhu, Guo-Qing|Zhou, Yi-Chan|He, Xiao-Pu|Sun, Wei-Hao
PMID: 23376640
48.
Journal: Onkologie. 2013;36(1-2):26-31.
Title: Markers CD40, VEGF, AKT, PI3K, and S100 correlate with tumor stage in gastric cancer.
Author: Tian, Wen-Yan|Chen, Wei-Chang|Li, Rui|Liu, Lei
PMID: 23429328
49.
Journal: Cancer Cell Int. 2013 Feb 21;13(1):18.
Title: Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer.
Author: Xie, Biao|Zhou, Jianping|Shu, Guoshun|Liu, Dong-Cai|Zhou, Jiapeng|Chen, Jinhui|Yuan, Lianwen
PMID: 23432957
50.
Journal: Toxicology. 2013 Apr 5;306:162-8.
Title: miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN.
Author: Yang, Shou-Mei|Huang, Cheng|Li, Xiao-Feng|Yu, Ming-Zhe|He, Yong|Li, Jun
PMID: 23466500
51.
Journal: World J Gastroenterol. 2013 Feb 28;19(8):1239-46.
Title: Effect of silencing of high mobility group A2 gene on gastric cancer MKN-45 cells.
Author: Wei, Chun-Hui|Wei, Li-Xiu|Lai, Ming-Yu|Chen, Jia-Zhuang|Mo, Xi-Jing
PMID: 23482887
52.
Journal: Int J Oncol. 2013 May;42(5):1682-91.
Title: PTEN expression and suppression of proliferation are associated with Cdx2 overexpression in gastric cancer cells.
Author: Bai, Zhi-Gang|Ye, Ying-Jiang|Shen, Dan-Hua|Lu, You-Yong|Zhang, Zhong-Tao|Wang, Shan
PMID: 23546539
53.
Journal: PLoS One. 2013;8(3):e60080.
Title: A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.
Author: Xu, Ming|Tao, Guoquan|Kang, Meiyun|Gao, Yan|Zhu, Haixia|Gong, Weida|Wang, Meilin|Wu, Dongmei|Zhang, Zhengdong|Zhao, Qinghong
PMID: 23555892
54.
Journal: Korean J Gastroenterol. 2013 Mar 25;61(3):117-27.
Title: [Perspectives of the stomach cancer treatment: the introduction of molecular targeted therapy and the hope for cure].
Author: Cheung, Dae Young|Kim, Jae Kwang
PMID: 23575230
55.
Journal: Oncol Rep. 2013 Aug;30(2):773-82.
Title: Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.
Author: Xie, Xia|Tang, Bo|Zhou, Jianyun|Gao, Qing|Zhang, Pengbing
PMID: 23743572
56.
Journal: Int J Mol Sci. 2013 Jun 24;14(7):13005-21.
Title: Anti-tumor effects of Mfn2 in gastric cancer.
Author: Zhang, Ge-Er|Jin, Hai-Long|Lin, Xian-Ke|Chen, Chao|Liu, Xiao-Sun|Zhang, Qing|Yu, Ji-Ren
PMID: 23797661
57.
Journal: Histol Histopathol. 2013 Dec;28(12):1629-38.
Title: Upregulation of GPR34 expression affects the progression and prognosis of human gastric adenocarcinoma by PI3K/PDK1/AKT pathway.
Author: Yu, Weidong|Ma, Shuyun|Wang, Lihong|Zuo, Bo|Li, Mei|Qiao, Zhengguo|Pan, Xiuying|Liu, Yulan|Wang, Jingtong
PMID: 23836308
58.
Journal: Int J Oncol. 2013 Oct;43(4):1059-65.
Title: Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-beta1 and integrin expression.
Author: Kim, Young-Min|Kim, In-Hye|Nam, Taek-Jeong
PMID: 23934170
59.
Journal: Nat Rev Clin Oncol. 2013 Nov;10(11):643-55.
Title: Gastric cancer-molecular and clinical dimensions.
Author: Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A
PMID: 24061039
60.
Journal: Breast Cancer Res. 2013 Nov 19;15(6):R110.
Title: A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors.
Author: Hudis, Clifford|Swanton, Charles|Janjigian, Yelena Y|Lee, Ray|Sutherland, Stephanie|Lehman, Robert|Chandarlapaty, Sarat|Hamilton, Nicola|Gajria, Devika|Knowles, James|Shah, Jigna|Shannon, Keith|Tetteh, Ernestina|Sullivan, Daniel M|Moreno, Carolina|Yan, Li
PMID: 24252402
61.
Journal: Oncol Lett. 2013 Dec;6(6):1723-1728.
Title: Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells.
Author: Wu, Min|Chen, Yongchang|Jiang, Lu|Li, Yueying|Lan, Ting|Wang, Ying|Qian, Hai
PMID: 24273605
62.
Journal: Infect Agent Cancer. 2013 Dec 13;8(1):49.
Title: Akt inhibitors: mechanism of action and implications for anticancer therapeutics.
Author: Bhutani, Jaikrit|Sheikh, Asfandyar|Niazi, Asfandyar Khan
PMID: 24330834
63.
Journal: Biomed Pharmacother. 2014 Mar;68(2):179-83.
Title: Tamoxifen reduces P-gp-mediated multidrug resistance via inhibiting the PI3K/Akt signaling pathway in ER-negative human gastric cancer cells.
Author: Mao, Zonglei|Zhou, Jin|Luan, Junwei|Sheng, Weihua|Shen, Xiaochun|Dong, Xiaoqiang
PMID: 24184201
64.
Journal: Oncogene. 2014 Nov 13;33(46):5341-7.
Title: PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling.
Author: Yun, S M|Yoon, K|Lee, S|Kim, E|Kong, S-H|Choe, J|Kang, J M|Han, T-S|Kim, P|Choi, Y|Jho, S|Yoo, H|Bhak, J|Yang, H-K|Kim, S-J
PMID: 24276243
65.
Journal: Pharmacology. 2014;93(1-2):39-46.
Title: Celastrol induces apoptosis of gastric cancer cells by miR-21 inhibiting PI3K/Akt-NF-kappaB signaling pathway.
Author: Sha, Min|Ye, Jun|Zhang, Li-xin|Luan, Zheng-yun|Chen, Ya-bao|Huang, Jun-xing
PMID: 24434352
66.
Journal: Mol Med Rep. 2014 Apr;9(4):1371-5.
Title: Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.
Author: Yang, Gongli|Ma, Feng|Zhong, Muxiao|Fang, Lin|Peng, Yao|Xin, Xiaoming|Zhong, Jietao|Zhu, Wei|Zhang, Yali
PMID: 24504547
67.
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Feb;17(2):168-74.
Title: [Relationship between CD133 and chemoresistance in human gastric cancer and its associated mechanism].
Author: Zhu, Youlong|Jiang, Bojian|Cai, Cheng|Wang, Shoulian|Wu, Jugang|Yu, Jiwei
PMID: 24577774
68.
Journal: Med Oncol. 2014 Apr;31(4):903.
Title: Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway.
Author: Wu, Xiaoyu|Chen, Yun|Li, Gang|Xia, Lei|Gu, Rongmin|Wen, Xu|Ming, Xuezhi|Chen, Huanqiu
PMID: 24623015
69.
Journal: Int J Mol Med. 2014 Jun;33(6):1451-8.
Title: Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells.
Author: Liu, Min|Li, Chun-Mei|Chen, Zhao-Feng|Ji, Ri|Guo, Qing-Hong|Li, Qiang|Zhang, Hong-Ling|Zhou, Yong-Ning
PMID: 24676394
70.
Journal: Cancer Sci. 2014 Jun;105(6):651-9.
Title: MGr1-Ag/37LRP induces cell adhesion-mediated drug resistance through FAK/PI3K and MAPK pathway in gastric cancer.
Author: Sun, Li|Liu, Lili|Liu, Xiangqiang|Wang, Yafang|Li, Mengbin|Yao, Liping|Yang, Jianjun|Ji, Genlin|Guo, Changcun|Pan, Yanglin|Liang, Shuhui|Wang, Biaoluo|Ding, Jie|Zhang, Hongwei|Shi, Yongquan
PMID: 24703465
71.
Journal: Biomed Pharmacother. 2014 May;68(4):471-5.
Title: Clinicopathological significance of PI3K, Akt and survivin expression in gastric cancer.
Author: Gu, Yongjuan|Jin, Shidai|Wang, Feng|Hua, Yibin|Yang, Li|Shu, Yongqian|Zhang, Zhihong|Guo, Renhua
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72.
Journal: Virchows Arch. 2014 Jul;465(1):25-33.
Title: The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance.
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Journal: Tumour Biol. 2014 Aug;35(8):8217-23.
Title: Molecular basis underlying inhibition of metastasis of gastric cancer by anti-VEGFa treatment.
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Journal: Cancers (Basel). 2014 Jul 7;6(3):1441-63.
Title: The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma.
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Journal: Biomol Ther (Seoul). 2014 May;22(3):184-92.
Title: beta-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway.
Author: Yu, Hai Yang|Kim, Sung Ok|Jin, Cheng-Yun|Kim, Gi-Young|Kim, Wun-Jae|Yoo, Young Hyun|Choi, Yung Hyun
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76.
Journal: Oncotarget. 2014 Jul 30;5(14):5798-807.
Title: Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells.
Author: Liang, Xiuming|Zeng, Jiping|Wang, Lixiang|Shen, Li|Li, Shuyan|Ma, Lin|Ci, Xinyu|Yu, Jingya|Jia, Mutian|Sun, Yundong|Liu, Zhifang|Liu, Shili|Li, Wenjuan|Yu, Han|Chen, Chunyan|Jia, Jihui
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Journal: Pol J Pathol. 2014 Jun;65(2):135-40.
Title: Expression of insulin-like growth factor receptor type 1 correlate with lymphatic metastases in human gastric cancer.
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Journal: Biomed Pharmacother. 2014 Jul;68(6):809-12.
Title: The role of HER3 in gastric cancer.
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79.
Journal: PLoS One. 2014 Nov 14;9(11):e112908.
Title: CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.
Author: Zang, Mingde|Zhang, Baogui|Zhang, Yunqiang|Li, Jianfang|Su, Liping|Zhu, Zhenggang|Gu, Qinlong|Liu, Bingya|Yan, Min
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Journal: Int J Clin Exp Pathol. 2014 Sep 15;7(10):7286-96. eCollection 2014.
Title: MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer.
Author: Lu, Weidong|Xu, Zhen|Zhang, Min|Zuo, Yun
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Journal: Gastrointest Tumors. 2014 May;1(4):180-94.
Title: Gastric Cancer: New Drugs - New Strategies.
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Journal: Biosci Rep. 2014 Apr 1;34(2). pii: BSR20130102.
Title: PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways.
Author: Fu, Xueqiong|Feng, Jiarui|Zeng, Duan|Ding, Yu|Yu, Changshou|Yang, Bing
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Journal: Mol Med Rep. 2015 Mar;11(3):1891-8.
Title: Effects of 5fluorouracil and class III phosphoinositide 3kinase small interfering RNA combination therapy on SGC7901 human gastric cancer cells.
Author: Zhu, Bao-Song|Sun, Jia-Lei|Gong, Wei|Zhang, Xing-Ding|Wu, Yong-You|Xing, Chun-Gen
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84.
Journal: Mol Med Rep. 2015 Mar;11(3):2269-75.
Title: Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib.
Author: Ma, Jin-An|Hu, Chunhong|Li, Wenjuan|Ren, Jing|Zou, Fangwen|Zhou, Dongai|Zou, Wen|Wei, Yajun|Zhou, Ying
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Journal: Oncol Lett. 2015 Jan;9(1):143-148.
Title: Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3beta and ZEB2 in the BGC-823 gastric cancer cell line.
Author: Li, Heming|Xu, Ling|Zhao, Lei|Ma, Yanju|Zhu, Zhitu|Liu, Yunpeng|Qu, Xiujuan
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Journal: Med Oncol. 2015 Jan;32(1):447.
Title: The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions.
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Journal: Med Oncol. 2015 Feb;32(2):467.
Title: CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in gastric cancer.
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Journal: Cell Cycle. 2015;14(5):732-43.
Title: Frequent amplification of PTP1B is associated with poor survival of gastric cancer patients.
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Journal: Drug Des Devel Ther. 2015 Jan 14;9:487-508.
Title: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
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Journal: Cancer Gene Ther. 2015 Apr;22(3):145-53.
Title: HER-2-induced PI3K signaling pathway was involved in the pathogenesis of gastric cancer.
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Journal: Chin Med J (Engl). 2015 Feb 20;128(4):545-9.
Title: G-protein coupled receptor 34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro.
Author: Jin, Zhong-Tian|Li, Kun|Li, Mei|Ren, Zhi-Gang|Wang, Fu-Shun|Zhu, Ji-Ye|Leng, Xi-Sheng|Yu, Wei-Dong
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Journal: Sci Rep. 2015 Feb 16;5:8473.
Title: Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer.
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Journal: Cell Signal. 2015 Jun;27(6):1075-86.
Title: Upregulated, 7q21-22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer.
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Journal: Int J Biol Macromol. 2015 May;76:242-53.
Title: Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis.
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Journal: Cancer Lett. 2015 May 28;361(1):57-66.
Title: Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis.
Author: Hao, Ning-Bo|Tang, Bo|Wang, Guo-Zheng|Xie, Rui|Hu, Chang-Jiang|Wang, Su-Min|Wu, Yu-Yun|Liu, En|Xie, Xia|Yang, Shi-Ming
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Journal: Drug Des Devel Ther. 2015 Mar 2;9:1293-318.
Title: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N
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Journal: Dig Dis Sci. 2015 Aug;60(8):2338-45.
Title: Hyperglycemia Promotes Human Gastric Carcinoma Progression via Aquaporin 3.
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Journal: Mol Cancer Ther. 2015 May;14(5):1213-23.
Title: Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.
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Journal: J Cancer Prev. 2015 Mar;20(1):50-6.
Title: Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells.
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Journal: Int J Oncol. 2015;46(6):2355-63.
Title: Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells.
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Journal: Oncotarget. 2015;6(12):9794-806.
Title: Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer.
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Journal: Sci Rep. 2015 May 18;5:10336.
Title: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways.
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Journal: Am J Cancer Res. 2015 Mar 15;5(4):1423-34. eCollection 2015.
Title: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling.
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Journal: World J Gastroenterol. 2015 Jun 21;21(23):7197-207.
Title: Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling.
Author: Zheng, Yong-Bin|Xiao, Gao-Chun|Tong, Shi-Lun|Ding, Yu|Wang, Qiu-Shuang|Li, Sheng-Bo|Hao, Zhi-Nan
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Journal: Oncol Lett. 2015 Jul;10(1):502-508.
Title: Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells.
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Journal: Int J Oncol. 2015 Sep;47(3):1061-9.
Title: Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells.
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Journal: Oncol Rep. 2015 Oct;34(4):2179-87.
Title: HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-kappaB activation.
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Journal: PLoS Comput Biol. 2015 Aug 28;11(8):e1004426.
Title: Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling.
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Journal: PLoS One. 2015 Aug 28;10(8):e0136447.
Title: Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
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Journal: Onco Targets Ther. 2015 Sep 1;8:2427-33.
Title: The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis.
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Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2015 Oct;37(5):514-9.
Title: [miR-29b Reduces Cisplatin Resistance of Gastric Cancer Cell by Targeting PI3K/Akt Pathway].
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Journal: Exp Ther Med. 2015 Sep;10(3):1212-1218.
Title: Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Author: Xie, Hua-Xia|Xu, Zhi-Yuan|Tang, Jia-Ning|DU, Yi-An|Huang, Ling|Yu, Peng-Fei|Cheng, Xiang-Dong
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Journal: Oncol Lett. 2015 Oct;10(4):1947-1952.
Title: Role of annexin A6 in cancer.
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Journal: Biotechnol Appl Biochem. 2016 Nov;63(6):841-851.
Title: Potential role of O-GlcNAcylation and involvement of PI3K/Akt1 pathway in the expression of oncogenic phenotypes of gastric cancer cells in vitro.
Author: Zhang, Nuobei|Chen, Xin
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Journal: Oncol Rep. 2016 Jan;35(1):472-8.
Title: Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway.
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Journal: J Recept Signal Transduct Res. 2016 Oct;36(5):471-7.
Title: 5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone, a polymethoxyflavone, exerts antitumor effect on PI3K/Akt signaling pathway in human gastric cancer cell BGC-7901.
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Journal: Tumour Biol. 2016 Jul;37(7):9169-79.
Title: The proliferation impairment induced by AQP3 deficiency is the result of glycerol uptake and metabolism inhibition in gastric cancer cells.
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Journal: Tumour Biol. 2016 Jul;37(7):9221-32.
Title: DCT015, a new sorafenib derivate, inhibits tumor growth and angiogenesis in gastric cancer models.
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Journal: Gastroenterology. 2016 May;150(5):1183-1195.e16.
Title: C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits.
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Journal: Cancer Cell Int. 2016 Feb 12;16:5.
Title: Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells.
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Journal: Cell Biochem Funct. 2016 Apr;34(3):173-80.
Title: PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways.
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Journal: Oncol Lett. 2016 Mar;11(3):1745-1749.
Title: miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway.
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Journal: Nutr Cancer. 2016;68(2):267-79.
Title: Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.
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Journal: Oncotarget. 2016 May 3;7(18):25391-407.
Title: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma.
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Journal: Oncotarget. 2016 May 31;7(22):33152-64.
Title: AURKA induces EMT by regulating histone modification through Wnt/beta-catenin and PI3K/Akt signaling pathway in gastric cancer.
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Journal: Oncotarget. 2016 Jun 7;7(23):34190-200.
Title: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.
Author: Wu, Yan|Yao, Xiaoyuan|Zhu, Miaolin|Qian, Hai|Jiang, Lu|Lan, Ting|Wu, Min|Pang, Ji|Chen, Yongchang
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Journal: Oncotarget. 2016 Jun 14;7(24):36865-36884.
Title: JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
Author: Qian, Jing|Zhu, Weiyou|Wang, Keming|Ma, Lin|Xu, Jin|Xu, Tongpeng|Roe, Oluf Dimitri|Li, Aiping|Zhou, Jianwei|Shu, Yongqian
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Journal: Cancer Discov. 2016 Aug;6(8):838-851.
Title: High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.
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Journal: World J Gastroenterol. 2016 May 21;22(19):4638-50.
Title: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management.
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Journal: Phytomedicine. 2016 Jul 15;23(8):818-27.
Title: The natural secolignan peperomin E induces apoptosis of human gastric carcinoma cells via the mitochondrial and PI3K/Akt signaling pathways in vitro and in vivo.
Author: Wang, Xin-Zhi|Cheng, Ying|Wu, Hao|Li, Na|Liu, Rui|Yang, Xiao-Lin|Qiu, Yun-Ying|Wen, Hong-Mei|Liang, Jing-Yu
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Journal: Cancer Biomark. 2016 Jun 7;17(1):1-10.
Title: Autophagy regulation and its role in gastric cancer and colorectal cancer.
Author: Zhou, Huangyan|Yuan, Min|Yu, Qiongfang|Zhou, Xiaoyan|Min, Weiping|Gao, Dian
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Journal: Tumour Biol. 2016 Sep;37(9):12403-12410.
Title: Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3beta signaling in gastric cancer.
Author: Dai, Jin|Qian, Chenchen|Su, Mingli|Chen, Minhu|Chen, Jie
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Journal: Mol Med Rep. 2016 Aug;14(2):1849-56.
Title: Type II cGMPdependent protein kinase inhibits EGFinduced JAK/STAT signaling in gastric cancer cells.
Author: Wu, Min|Wu, Yan|Lan, Ting|Jiang, Lu|Qian, Hai|Chen, Yongchang
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Journal: Biomed Pharmacother. 2016 Aug;82:479-88.
Title: CXCL10/CXCR3 axis promotes the invasion of gastric cancer via PI3K/AKT pathway-dependent MMPs production.
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Journal: Mar Drugs. 2016 Jul 27;14(8). pii: md14080142.
Title: Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells.
Author: Wu, Yu-Jen|Wong, Bing-Sang|Yea, Shu-Hao|Lu, Chi-I|Weng, Shun-Hsiang
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Journal: J BUON. 2016 May-Jun;21(3):609-17.
Title: Amarogentin secoiridoid inhibits in vivo cancer cell growth in xenograft mice model and induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway.
Author: Zhao, Jian-Guo|Zhang, Ling|Xiang, Xiao-Jun|Yu, Feng|Ye, Wan-Li|Wu, Dong-Ping|Wang, Jian-Fang|Xiong, Jian-Ping
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Journal: Oncol Rep. 2016 Oct;36(4):1819-28.
Title: PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN.
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Journal: Adv Exp Med Biol. 2016;908:441-78.
Title: Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer.
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Journal: Tumour Biol. 2016 Nov;37(11):14637-14651.
Title: Bone marrow-derived mesenchymal stem cells increase drug resistance in CD133-expressing gastric cancer cells by regulating the PI3K/AKT pathway.
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Journal: Ann Clin Lab Sci. 2016 Sep;46(5):457-62.
Title: Matrine Suppresses Proliferation and Invasion of SGC7901 Cells through Inactivation of PI3K/Akt/uPA Pathway.
Author: Peng, Xiaochun|Zhou, Dawei|Wang, Xianwang|Hu, Zhifan|Yan, Yan|Huang, Jiangrong
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Journal: Oncotarget. 2016 Nov 8;7(45):72990-73002.
Title: Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
Author: Wang, Sai-Qi|Wang, Cong|Chang, Li-Ming|Zhou, Kai-Rui|Wang, Jun-Wei|Ke, Yu|Yang, Dong-Xiao|Shi, Hong-Ge|Wang, Ran|Shi, Xiao-Li|Ma, Li-Ying|Liu, Hong-Min
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Journal: Oncol Res. 2016;24(5):287-293.
Title: Knockdown of Rap1b Enhances Apoptosis and Autophagy in Gastric Cancer Cells via the PI3K/Akt/mTOR Pathway.
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Journal: Am J Cancer Res. 2016 Sep 1;6(9):1935-1948. eCollection 2016.
Title: Identification of HRAS as cancer-promoting gene in gastric carcinoma cell aggressiveness.
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Title: FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
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Title: Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer.
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Title: AKT inhibition is an effective treatment strategy in ARID1A-deficient gastric cancer cells.
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Title: Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway.
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Title: Downregulation of MicroRNA-147 Inhibits Cell Proliferation and Increases the Chemosensitivity of Gastric Cancer Cells to 5-Fluorouracil by Directly Targeting PTEN.
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Title: PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3beta/beta-Catenin Signaling Pathway in Human Gastric Cancer.
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Title: MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer.
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Title: Mcl-1 stabilization confers resistance to taxol in human gastric cancer.
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Title: Expression of the beta3 subunit of Na(+)/K(+)-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway.
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Title: Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene.
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Title: Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas.
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Title: DNA Methylation-Mediated Silencing of Regenerating Protein 1 Alpha (REG1A) Affects Gastric Cancer Prognosis.
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Title: Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway.
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Title: Long non-coding RNA CRNDE is a novel tumor promoter by modulating PI3K/AKT signal pathways in human gastric cancer.
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Title: LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway.
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Title: Imperatorin shows selective antitumor effects in SGC-7901 human gastric adenocarcinoma cells by inducing apoptosis, cell cycle arrest and targeting PI3K/Akt/m-TOR signalling pathway.
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Title: CD133 mediates the TGF-beta1-induced activation of the PI3K/ERK/P70S6K signaling pathway in gastric cancer cells.
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Title: Combination of cecropinXJ and LY294002 induces synergistic cytotoxicity, and apoptosis in human gastric cancer cells via inhibition of the PI3K/Akt signaling pathway.
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Title: Knockdown of long non-coding RNA HOTAIR inhibits cisplatin resistance of gastric cancer cells through inhibiting the PI3K/Akt and Wnt/beta-catenin signaling pathways by up-regulating miR-34a.
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Title: The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.
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Title: Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k-Akt signaling pathway.
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Title: Nectin-4 promotes gastric cancer progression via the PI3K/AKT signaling pathway.
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Title: NES1/KLK10 promotes trastuzumab resistance via activation of PI3K/AKT signaling pathway in gastric cancer.
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Title: MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway.
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Title: F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT.
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Title: Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway.
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Title: Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis.
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Title: Effect of silencing colon cancer-associated transcript 2 on the proliferation, apoptosis and autophagy of gastric cancer BGC-823 cells.
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Title: MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway.
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Title: Astragaloside IV inhibits TGF-beta1-induced epithelial-mesenchymal transition through inhibition of the PI3K/Akt/NF-kappaB pathway in gastric cancer cells.
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Title: Osthole inhibits gastric cancer cell proliferation through regulation of PI3K/AKT.
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Title: ERBB4 promotes the proliferation of gastric cancer cells via the PI3K/Akt signaling pathway.
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Title: Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab.
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Title: miR-1236-3p inhibits invasion and metastasis in gastric cancer by targeting MTA2.
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Title: Combined treatment with PI3K inhibitor BKM120 and PARP inhibitor olaparib is effective in inhibiting the gastric cancer cells with ARID1A deficiency.
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Title: High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer.
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Title: Inhibitor of growth 3 induces cell death by regulating cell proliferation, apoptosis and cell cycle arrest by blocking the PI3K/AKT pathway.
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Journal: Biosci Rep. 2018 Jun 13. pii: BSR20180741.
Title: Downregulation of HIF-1alpha inhibits the proliferation, migration and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression.
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Title: Overexpression of retinoblastomabinding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3kinase/protein kinase B pathway suppression.
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Title: HGF derived from cancerassociated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.
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Title: IL-1beta promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem-like properties through PI3K pathway.
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Title: PKG II inhibits PDGF-BB triggered biological activities by phosphorylating PDGFRbeta in gastric cancer cells.
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Journal: Neoplasma. 2018 Sep 19;65(5):693-700.
Title: Anticancer effect of YWHAZ silencing via inducing apoptosis and autophagy in gastric cancer cells.
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Title: Aclidinium bromide inhibits the growth and metastasis of gastric cancer MKN28 cells via the PI3K signaling pathway.
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Title: Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway.
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Title: miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop.
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Journal: Onco Targets Ther. 2018 Jul 19;11:4177-4187.
Title: DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3beta/beta-catenin signaling pathway.
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Journal: J Dig Dis. 2018 Jul 29.
Title: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer.
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Journal: Cell Physiol Biochem. 2018;48(4):1457-1467.
Title: Neogenin-1 Promotes Cell Proliferation, Motility, and Adhesion by Up-Regulation of Zinc Finger E-Box Binding Homeobox 1 Via Activating the Rac1/PI3K/AKT Pathway in Gastric Cancer Cells.
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Title: E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
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Title: Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
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Title: Down-regulation of lncRNA ADAMTS9-AS2 contributes to gastric cancer development via activation of PI3K/Akt pathway.
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Journal: Sheng Li Xue Bao. 2018 Aug 25;70(4):397-405.
Title: [Wogonoside reverses cisplatin resistance in SGC7901/cDDP cells through inhibition of PI3K/Akt/Nrf2/ARE signaling pathway].
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Title: Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3-kinase/protein kinase B/glycogen synthase kinase 3beta signaling pathway.
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Title: Knockdown of long noncoding RNA urothelial carcinoma-associated 1 inhibits cell viability, migration, and invasion by regulating microRNA-182 in gastric carcinoma.
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Journal: Med Sci Monit. 2018 Aug 22;24:5840-5850.
Title: High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer.
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Title: Sh-MARCH8 Inhibits Tumorigenesis via PI3K Pathway in Gastric Cancer.
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Title: Knockdown of TMPRSS3 inhibits gastric cancer cell proliferation, invasion and EMT via regulation of the ERK1/2 and PI3K/Akt pathways.
Author: Li, Shun-Le|Chen, Xi|Wu, Tao|Zhang, Xin-Wu|Li, Hua|Zhang, Yan|Ji, Zong-Zheng
PMID: 30142546
218.
Journal: Anticancer Drugs. 2018 Aug 30.
Title: Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways.
Author: Lin, Fuxing|Yang, Jie|Muhammad, Umair|Sun, Jing|Huang, Zhenghua|Li, Wei|Lv, Fengxia|Lu, Zhaoxin
PMID: 30169424
219.
Journal: Exp Mol Pathol. 2018 Aug 31. pii: S0014-4800(18)30307-1.
Title: Geniposide suppresses growth, migration and invasion of MKN45 cells by down-regulation of lncRNA HULC.
Author: Ma, Ji|Ding, Yong
PMID: 30176223
220.
Journal: Surg Oncol. 2018 Sep;27(3):495-502.
Title: Knockdown of CEACAM19 suppresses human gastric cancer through inhibition of PI3K/Akt and NF-kappaB.
Author: Zhao, Hongying|Xu, Jianjun|Wang, Yu|Jiang, Rongke|Li, Xue|Zhang, Lili|Che, Yingqi
PMID: 30217308
221.
Journal: J Cell Biochem. 2018 Sep 23.
Title: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling.
Author: Wang, Honglei|Zhao, Yongjie|Cao, Lei|Zhang, Judong|Wang, Yu|Xu, Min
PMID: 30246429
222.
Journal: Oncotarget. 2018 Aug 31;9(68):32917-32928.
Title: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer.
Author: Sugase, Takahito|Takahashi, Tsuyoshi|Serada, Satoshi|Fujimoto, Minoru|Ohkawara, Tomoharu|Hiramatsu, Kosuke|Koh, Masahiro|Saito, Yurina|Tanaka, Koji|Miyazaki, Yasuhiro|Makino, Tomoki|Kurokawa, Yukinori|Yamasaki, Makoto|Nakajima, Kiyokazu|Hanazaki, Kazuhiro
PMID: 30250639
223.
Journal: Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title: F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author: Yao, Hui|Su, Song|Xia, Dong|Wang, Mingming|Li, Zonglin|Chen, Wangsheng|Ren, Lei|Xu, Liang
PMID: 30257389
224.
Journal: Oncol Rep. 2018 Sep 21.
Title: MicroRNA495 regulates human gastric cancer cell apoptosis and migration through Akt and mTOR signaling.
Author: Wang, Jun|Feng, Weiwei|Dong, Yuanqiang|Mao, Xiang|Guo, Fenghua|Luo, Fen
PMID: 30272336
225.
Journal: Onco Targets Ther. 2018 Sep 20;11:6111-6118.
Title: Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy.
Author: Li, Liangqing|Zhang, Shengwei|Xie, Diya|Chen, Hui|Zheng, Xuelan|Pan, Dun
PMID: 30275715
226.
Journal: Int J Oncol. 2018 Oct 12.
Title: Downregulation of microRNA-4295 enhances cisplatin-induced gastric cancer cell apoptosis through the EGFR/PI3K/Akt signaling pathway by targeting LRIG1.
Author: Yan, Rong|Li, Kang|Yuan, Da-Wei|Wang, Hao-Nan|Zhang, Yong|Dang, Cheng-Xue|Zhu, Kun
PMID: 30320337
227.
Journal: Int Immunopharmacol. 2018 Oct 18;65:312-322.
Title: Methionine enkephalin (MENK) inhibits human gastric cancer through regulating tumor associated macrophages (TAMs) and PI3K/AKT/mTOR signaling pathway inside cancer cells.
Author: Wang, Xiaonan|Jiao, Xue|Meng, Yiming|Chen, Hao|Griffin, Noreen|Gao, Xinghua|Shan, Fengping
PMID: 30343258
228.
Journal: Oncol Lett. 2018 Nov;16(5):5615-5620.
Title: Analysis of correlation between HP infection and activation of PI3K/Akt pathway in mucosal tissues of gastric cancer and precancerous lesions.
Author: Xie, Yi|Liu, Li
PMID: 30344716
229.
Journal: Onco Targets Ther. 2018 Oct 10;11:6705-6722.
Title: Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1alpha signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo.
Author: Chen, Min|Lu, Jian|Wei, Wei|Lv, Ying|Zhang, Xiaoqi|Yao, Yuling|Wang, Lei|Ling, Tingsheng|Zou, Xiaoping
PMID: 30349304
230.
Journal: Carcinogenesis. 2018 Oct 29. pii: 5146213.
Title: NUCKS1 promotes gastric cancer cell aggressiveness by upregulating IGF-1R and subsequently activating the PI3K/Akt/mTOR signaling pathway.
Author: Huang, Ya-Kai|Kang, Wei-Ming|Ma, Zhi-Qiang|Liu, Yu-Qin|Zhou, Li|Yu, Jian-Chun
PMID: 30371738