Primary Site >> Esophagus Cancer
Gene >> PIK3CD
| 1. | |||||||||||
| Journal: | Acta Med Okayama. 2006 Feb;60(1):25-34. | ||||||||||
| Title: | Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro. | ||||||||||
| Author: | Taira, Naruto|Doihara, Hiroyoshi|Oota, Tetsuya|Hara, Fumikata|Shien, Tadahiko|Takahashi, Hirotoshi|Yoshitomi, Seiji|Ishibe, Youichi|Shimizu, Nobuyoshi | ||||||||||
| PMID: | 16508686 | ||||||||||
| 2. | |||||||||||
| Journal: | Anticancer Res. 2009 Apr;29(4):1163-8. | ||||||||||
| Title: | Gene expression changes in a chemoresistant model with human esophageal cancer xenografts using cDNA microarray. | ||||||||||
| Author: | Yoshida, Takahiro|Miyoshi, Takanori|Seike, Jun-Ichi|Yamai, Hiromichi|Takechi, Hirokazu|Yuasa, Yasuhiro|Tangoku, Akira | ||||||||||
| PMID: | 19414360 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2009 Dec 1;125(11):2576-85. | ||||||||||
| Title: | Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. | ||||||||||
| Author: | Li, Bin|Tsao, Sai Wah|Li, Yuk Yin|Wang, Xianghong|Ling, Ming Tat|Wong, Yong Chuan|He, Qing Yu|Cheung, Annie L M | ||||||||||
| PMID: | 19551863 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Cancer Res. 2011 Apr;9(4):390-402. | ||||||||||
| Title: | Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway. | ||||||||||
| Author: | Liu, Shu-Guang|Wang, Bo-Shi|Jiang, Yan-Yi|Zhang, Tong-Tong|Shi, Zhi-Zhou|Yang, Yang|Yang, Yi-Ling|Wang, Xiao-Chun|Lin, De-Chen|Zhang, Yu|Yang, Hai|Cai, Yan|Zhan, Qi-Min|Wang, Ming-Rong | ||||||||||
| PMID: | 21310827 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Biol Ther. 2011 Jun 1;11(11):950-8. Epub 2011 Jun 1. | ||||||||||
| Title: | The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. | ||||||||||
| Author: | Li, Hongxia|Gao, Quanli|Guo, Liping|Lu, Shih Hsin | ||||||||||
| PMID: | 21467840 | ||||||||||
| 6. | |||||||||||
| Journal: | BMC Cell Biol. 2011 Sep 27;12:41. | ||||||||||
| Title: | Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells. | ||||||||||
| Author: | Tonoike, Yurie|Matsushita, Kazuyuki|Tomonaga, Takeshi|Katada, Koji|Tanaka, Nobuko|Shimada, Hideaki|Nakatani, Yukio|Okamoto, Yoshitaka|Nomura, Fumio | ||||||||||
| PMID: | 21951621 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Carcinog. 2012 Oct;51(10):796-806. | ||||||||||
| Title: | Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation. | ||||||||||
| Author: | Zare, Maryam|Jazii, Ferdous Rastgar|Soheili, Zahra-Soheila|Moghanibashi, Mohamad-Mehdi | ||||||||||
| PMID: | 22965424 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Cycle. 2012 Nov 1;11(21):3997-4008. | ||||||||||
| Title: | Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. | ||||||||||
| Author: | Werneck, Miriam B F|Hottz, Eugenio|Bozza, Patricia T|Viola, Joao P B | ||||||||||
| PMID: | 22992618 | ||||||||||
| 9. | |||||||||||
| Journal: | Chin Med J (Engl). 2014;127(2):353-8. | ||||||||||
| Title: | Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy. | ||||||||||
| Author: | Yang, Yang|Wen, Fengbiao|Dang, Lifeng|Fan, Yuxia|Liu, Donglei|Wu, Kai|Zhao, Song | ||||||||||
| PMID: | 24438628 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncotarget. 2014 Nov 30;5(22):11576-87. | ||||||||||
| Title: | Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. | ||||||||||
| Author: | Li, Bin|Li, Jin|Xu, Wen Wen|Guan, Xin Yuan|Qin, Yan Ru|Zhang, Li Yi|Law, Simon|Tsao, Sai Wah|Cheung, Annie L M | ||||||||||
| PMID: | 25344912 | ||||||||||
| 11. | |||||||||||
| Journal: | Drug Des Devel Ther. 2015 Feb 17;9:993-1026. | ||||||||||
| Title: | Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. | ||||||||||
| Author: | Wang, Yan-Yang|Yang, Yin-Xue|Zhao, Ren|Pan, Shu-Ting|Zhe, Hong|He, Zhi-Xu|Duan, Wei|Zhang, Xueji|Yang, Tianxin|Qiu, Jia-Xuan|Zhou, Shu-Feng | ||||||||||
| PMID: | 25733817 | ||||||||||
| 12. | |||||||||||
| Journal: | Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Sep;31(5):465-8. | ||||||||||
| Title: | [The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells]. | ||||||||||
| Author: | Li, Xiu-juan|Luo, Qiang|Sun, Li|Lit, Hua|Jin, Chun-ting|Fan, Jie|Li, Yu-zhen | ||||||||||
| PMID: | 26827544 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncotarget. 2015 Oct 20;6(32):33438-55. | ||||||||||
| Title: | Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation. | ||||||||||
| Author: | Kresty, Laura A|Weh, Katherine M|Zeyzus-Johns, Bree|Perez, Laura N|Howell, Amy B | ||||||||||
| PMID: | 26378019 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):25897-916. | ||||||||||
| Title: | IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. | ||||||||||
| Author: | Myers, Amy L|Lin, Lin|Nancarrow, Derek J|Wang, Zhuwen|Ferrer-Torres, Daysha|Thomas, Dafydd G|Orringer, Mark B|Lin, Jules|Reddy, Rishindra M|Beer, David G|Chang, Andrew C | ||||||||||
| PMID: | 26317790 | ||||||||||
| 15. | |||||||||||
| Journal: | Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Mar;31(2):174-7. | ||||||||||
| Title: | [Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells]. | ||||||||||
| Author: | Li, Xiu-juan|Li, Yu-zhen|Jin, Chun-ting|Fan, Jie|Li, Hai-jun | ||||||||||
| PMID: | 26248429 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 May 1;8(5):5080-8. eCollection 2015. | ||||||||||
| Title: | Over-expression of Orai1 mediates cell proliferation and associates with poor prognosis in human non-small cell lung carcinoma. | ||||||||||
| Author: | Zhan, Zheng-Yu|Zhong, Lu-Xing|Feng, Miao|Wang, Jian-Feng|Liu, Di-Bin|Xiong, Jian-Ping | ||||||||||
| PMID: | 26191202 | ||||||||||
| 17. | |||||||||||
| Journal: | Cell Signal. 2015 Feb;27(2):373-81. | ||||||||||
| Title: | ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts. | ||||||||||
| Author: | Kebenko, Maxim|Drenckhan, Astrid|Gros, Stephanie J|Jucker, Manfred|Grabinski, Nicole|Ewald, Florian|Grottke, Astrid|Schultze, Alexander|Izbicki, Jakob R|Bokemeyer, Carsten|Wellbrock, Jasmin|Fiedler, Walter | ||||||||||
| PMID: | 25435423 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Lett. 2016 Nov;12(5):3598-3608. Epub 2016 Sep 5. | ||||||||||
| Title: | Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. | ||||||||||
| Author: | Lu, Qiu-Ping|Chen, Wen-Dan|Peng, Jie-Ren|Xu, Yao-Dong|Cai, Qian|Feng, Gong-Kan|Ding, Ke|Zhu, Xiao-Feng|Guan, Zhong | ||||||||||
| PMID: | 27900042 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncol Lett. 2016 Aug;12(2):971-976. Epub 2016 Jun 15. | ||||||||||
| Title: | Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-kappaB and PI3K/Akt signaling pathways. | ||||||||||
| Author: | Jin, Zhiliang|Yan, Wei|Jin, Hui|Ge, Changzheng|Xu, Yanhua | ||||||||||
| PMID: | 27446379 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Med Rep. 2016 Aug;14(2):1531-7. | ||||||||||
| Title: | Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells. | ||||||||||
| Author: | Yang, Peng|Zhao, Jiaying|Hou, Liying|Yang, Lei|Wu, Kun|Zhang, Linyou | ||||||||||
| PMID: | 27357907 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Biol Int. 2016 May;40(5):524-33. | ||||||||||
| Title: | FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro. | ||||||||||
| Author: | Shi, Hui|Xu, Jingjing|Zhao, Rui|Wu, Huiqun|Gu, Luo|Chen, Yijiang | ||||||||||
| PMID: | 26833879 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Med Rep. 2016 Feb;13(2):1097-104. | ||||||||||
| Title: | Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling. | ||||||||||
| Author: | Tantai, Ji-Cheng|Zhang, Yao|Zhao, Heng | ||||||||||
| PMID: | 26647768 | ||||||||||
| 23. | |||||||||||
| Journal: | Tumour Biol. 2016 Sep;37(9):12061-12070. Epub 2016 May 17. | ||||||||||
| Title: | MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer. | ||||||||||
| Author: | Wu, Yan-Ran|Qi, Hai-Jun|Deng, Dan-Fang|Luo, Ying-Ying|Yang, Sheng-Lan | ||||||||||
| PMID: | 27188433 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Res Treat. 2017 Jul;49(3):778-789. | ||||||||||
| Title: | Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. | ||||||||||
| Author: | Tang, Jian-Cai|An, Rui|Jiang, Yi-Qing|Yang, Jian | ||||||||||
| PMID: | 27857021 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncol Res. 2017 Aug 7;25(7):1061-1068. | ||||||||||
| Title: | Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells. | ||||||||||
| Author: | Fan, Huijie|Li, Jing|Jia, Yongxu|Wu, Jingjing|Yuan, Long|Li, Mingjun|Wei, Jiangqi|Xu, Benling | ||||||||||
| PMID: | 28109079 | ||||||||||
| 26. | |||||||||||
| Journal: | J Cell Biochem. 2017 Aug 31. | ||||||||||
| Title: | FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Shi, Yuanyuan|Liu, Xuejiao|Fredimoses, Mangaladoss|Song, Mengqiu|Chen, Hanyong|Liu, Kangdong|Lee, Mee-Hyun|Dong, Zigang | ||||||||||
| PMID: | 28857247 | ||||||||||
| 27. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2017 Sep 1. pii: S0006-291X(17)31730-8. | ||||||||||
| Title: | Simultaneous targeting PI3K and PERK pathways promotes cell death and improves the clinical prognosis in esophageal squamous carcinoma. | ||||||||||
| Author: | Wang, Shao-Qi|Wang, Xiao|Zheng, Kai|Liu, Kai-Sheng|Wang, Shao-Xiang|Xie, Cong-Hua | ||||||||||
| PMID: | 28867195 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncol Res. 2017 Sep 6. | ||||||||||
| Title: | Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1. | ||||||||||
| Author: | Ma, Junxun|Wan, Lijie|Li, Jinyu|Zhang, Guoqing|Tao, Haitao|Li, Xiaoyan|Sun, Danyang|Hu, Yi | ||||||||||
| PMID: | 28899457 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncol Lett. 2017 Oct;14(4):4897-4905. | ||||||||||
| Title: | Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway. | ||||||||||
| Author: | Qian, Li-Qiang|Li, Xia-Qin|Ye, Peng-Hui|Su, Hao-Yuan|Wang, Gang|Liu, Yan|Shen, Gen-Hai|Gao, Quan-Gen | ||||||||||
| PMID: | 29085498 | ||||||||||
| 30. | |||||||||||
| Journal: | Med Sci Monit. 2018 Oct 28;24:7689-7696. | ||||||||||
| Title: | Long Non-Coding RNA (lncRNA) Growth Arrest Specific 5 (GAS5) Suppresses Esophageal Squamous Cell Carcinoma Cell Proliferation and Migration by Inactivating Phosphatidylinositol 3-kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. | ||||||||||
| Author: | Wang, Guojun|Sun, Junfeng|Zhao, Hongchao|Li, Haohao | ||||||||||
| PMID: | 30368517 | ||||||||||
| 31. | |||||||||||
| Journal: | Int J Mol Sci. 2018 Sep 20;19(10). pii: ijms19102861. | ||||||||||
| Title: | The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices. | ||||||||||
| Author: | Senthebane, Dimakatso Alice|Jonker, Tina|Rowe, Arielle|Thomford, Nicholas Ekow|Munro, Daniella|Dandara, Collet|Wonkam, Ambroise|Govender, Dhirendra|Calder, Bridget|Soares, Nelson C|Blackburn, Jonathan M|Parker, M Iqbal|Dzobo, Kevin | ||||||||||
| PMID: | 30241395 | ||||||||||
| 32. | |||||||||||
| Journal: | J Cell Biochem. 2018 Sep 19. | ||||||||||
| Title: | Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. | ||||||||||
| Author: | Jiang, Jin-Huan|Pi, Jiang|Jin, Hua|Cai, Ji-Ye | ||||||||||
| PMID: | 30229997 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Physiol Biochem. 2018;49(1):217-225. | ||||||||||
| Title: | RUNX2 Plays An Oncogenic Role in Esophageal Carcinoma by Activating the PI3K/AKT and ERK Signaling Pathways. | ||||||||||
| Author: | Lu, Huibin|Jiang, Tian|Ren, Kewei|Li, Zongming Li|Ren, Jianzhuang|Wu, Gang|Han, Xinwei | ||||||||||
| PMID: | 30138923 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncol Lett. 2018 Sep;16(3):3373-3379. | ||||||||||
| Title: | Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway. | ||||||||||
| Author: | Shang, Xiaobin|Liu, Guoyan|Zhang, Yuefeng|Tang, Peng|Zhang, Hongdian|Jiang, Hongjing|Yu, Zhentao | ||||||||||
| PMID: | 30127937 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncol Rep. 2018 Aug;40(2):1147-1155. | ||||||||||
| Title: | Gproteincoupled receptor 120 regulates the development and progression of human esophageal cancer. | ||||||||||
| Author: | Cui, Zhen|Li, Duojie|Liu, Jingjing|Zhang, Yajun|Xu, Hongbo|Yin, Hongmei|Li, Hongwei|Wang, Gengming|Cai, Hanfei|Zhang, Lei|Duan, Shimiao|Jiang, Hao | ||||||||||
| PMID: | 29901155 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Lett. 2018 Jul 1;425:88-100. | ||||||||||
| Title: | IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness. | ||||||||||
| Author: | Xu, Wen Wen|Li, Bin|Zhao, Jian Fu|Yang, Jing Ge|Li, Jun Qi|Tsao, Sai Wah|He, Qing-Yu|Cheung, Annie L M | ||||||||||
| PMID: | 29604392 | ||||||||||
| 37. | |||||||||||
| Journal: | Technol Cancer Res Treat. 2018 Jan 1;17:1533033818758772. | ||||||||||
| Title: | The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma. | ||||||||||
| Author: | Wu, Ning|Du, Zunguo|Zhu, Yongjun|Song, Yang|Pang, Liewen|Chen, Zhiming | ||||||||||
| PMID: | 29463194 | ||||||||||
| 38. | |||||||||||
| Journal: | Onco Targets Ther. 2018 Jan 4;11:211-220. | ||||||||||
| Title: | RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. | ||||||||||
| Author: | Liu, Bowen|Wang, Cong|Chen, Pengxiang|Cheng, Bo|Cheng, Yufeng | ||||||||||
| PMID: | 29379302 | ||||||||||
| 39. | |||||||||||
| Journal: | Exp Cell Res. 2018 Jan 15;362(2):362-369. | ||||||||||
| Title: | Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. | ||||||||||
| Author: | Jin, Yingying|Xu, Kun|Chen, Qingjuan|Wang, Baofeng|Pan, Jiyuan|Huang, Shan|Wei, Yang|Ma, Hongbing | ||||||||||
| PMID: | 29208461 | ||||||||||
| 40. | |||||||||||
| Journal: | Mol Med Rep. 2018 Jan;17(1):549-555. | ||||||||||
| Title: | UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. | ||||||||||
| Author: | He, Dan|Zhang, Suolin | ||||||||||
| PMID: | 29115622 | ||||||||||