Primary Site >> Esophagus Cancer
Gene >> PIK3CD
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Ref: Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro. PMID: 16508686 |
Ref: Gene expression changes in a chemoresistant model with human esophageal cancer xenografts using cDNA microarray. PMID: 19414360 Ref: Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. PMID: 19551863 |
Ref: Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway. PMID: 21310827 Ref: The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. PMID: 21467840 Ref: Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells. PMID: 21951621 |
Ref: Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation. PMID: 22965424 Ref: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. PMID: 22992618 |
Ref: Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy. PMID: 24438628 Ref: Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. PMID: 25344912 |
Ref: ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts. PMID: 25435423 Ref: Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. PMID: 25733817 Ref: Over-expression of Orai1 mediates cell proliferation and associates with poor prognosis in human non-small cell lung carcinoma. PMID: 26191202 Ref: [Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells]. PMID: 26248429 Ref: IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. PMID: 26317790 Ref: Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation. PMID: 26378019 Ref: [The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells]. PMID: 26827544 |
Ref: Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling. PMID: 26647768 Ref: FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro. PMID: 26833879 Ref: MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer. PMID: 27188433 Ref: Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells. PMID: 27357907 Ref: Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-kappaB and PI3K/Akt signaling pathways. PMID: 27446379 Ref: Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. PMID: 27900042 |
Ref: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. PMID: 27857021 Ref: Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells. PMID: 28109079 Ref: FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. PMID: 28857247 Ref: Simultaneous targeting PI3K and PERK pathways promotes cell death and improves the clinical prognosis in esophageal squamous carcinoma. PMID: 28867195 Ref: Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1. PMID: 28899457 Ref: Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway. PMID: 29085498 |
Ref: UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. PMID: 29115622 Ref: Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. PMID: 29208461 Ref: RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. PMID: 29379302 Ref: The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma. PMID: 29463194 Ref: IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness. PMID: 29604392 Ref: Gproteincoupled receptor 120 regulates the development and progression of human esophageal cancer. PMID: 29901155 Ref: Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway. PMID: 30127937 Ref: RUNX2 Plays An Oncogenic Role in Esophageal Carcinoma by Activating the PI3K/AKT and ERK Signaling Pathways. PMID: 30138923 Ref: Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. PMID: 30229997 Ref: The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices. PMID: 30241395 Ref: Long Non-Coding RNA (lncRNA) Growth Arrest Specific 5 (GAS5) Suppresses Esophageal Squamous Cell Carcinoma Cell Proliferation and Migration by Inactivating Phosphatidylinositol 3-kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. PMID: 30368517 |