Literatures

Primary Site >> Biliary tract Cancer

Gene >> PIK3CD

1.
Journal:	Int J Oncol. 2006 Apr;28(4):915-21.
Title:	The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Author:	Miyata, Hideki\|Sasaki, Tamito\|Kuwahara, Kenichi\|Serikawa, Masahiro\|Chayama, Kazuaki
PMID:	16525641

2.
Journal:	World J Gastroenterol. 2007 Mar 14;13(10):1561-8.
Title:	Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Author:	Leelawat, Kawin\|Leelawat, Surang\|Narong, Siriluck\|Hongeng, Suradej
PMID:	17461449

3.
Journal:	J Exp Clin Cancer Res. 2009 May 18;28:65.
Title:	Expression of phospho-ERK1/2 and PI3-K in benign and malignant gallbladder lesions and its clinical and pathological correlations.
Author:	Li, Qinglong\|Yang, Zhulin
PMID:	19445727

4.
Journal:	World J Gastroenterol. 2010 Feb 14;16(6):713-22.
Title:	Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion.
Author:	Menakongka, Apaporn\|Suthiphongchai, Tuangporn
PMID:	20135719

5.
Journal:	J Cancer Res Clin Oncol. 2010 Oct;136(10):1537-44.
Title:	Induction of MKP-1 prevents the cytotoxic effects of PI3K inhibition in hilar cholangiocarcinoma cells.
Author:	Leelawat, Kawin\|Udomchaiprasertkul, Wandee\|Narong, Siriluck\|Leelawat, Surang
PMID:	20145951

6.
Journal:	Int J Oncol. 2012 Sep;41(3):1110-8.
Title:	Periostin activates integrin alpha5beta1 through a PI3K/AKTdependent pathway in invasion of cholangiocarcinoma.
Author:	Utispan, Kusumawadee\|Sonongbua, Jumaporn\|Thuwajit, Peti\|Chau-In, Siri\|Pairojkul, Chawalit\|Wongkham, Sopit\|Thuwajit, Chanitra
PMID:	22735632

7.
Journal:	Genome Med. 2012 Jul 4;4(7):56.
Title:	Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability.
Author:	Demeure, Michael J\|Craig, David W\|Sinari, Shripad\|Moses, Tracy M\|Christoforides, Alexis\|Dinh, Jennifer\|Izatt, Tyler\|Aldrich, Jessica\|Decker, Ardis\|Baker, Angela\|Cherni, Irene\|Watanabe, April\|Koep, Lawrence\|Lake, Douglas\|Hostetter, Galen\|Trent, Jeffrey M\|V
PMID:	22762308

8.
Journal:	PLoS One. 2013 Nov 28;8(11):e81347.
Title:	Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma.
Author:	Sang, Haiquan\|Li, Tingting\|Li, Hangyu\|Liu, Jingang
PMID:	24312291

9.
Journal:	PLoS One. 2013 Apr 30;8(4):e62844.
Title:	Suppression of cholangiocarcinoma cell growth by human umbilical cord mesenchymal stem cells: a possible role of Wnt and Akt signaling.
Author:	Liu, Juan\|Han, Guoqing\|Liu, Hui\|Qin, Chengyong
PMID:	23646150

10.
Journal:	Int J Oncol. 2013 Jun;42(6):2103-15.
Title:	Contribution of the PI3K/MMPs/Ln-5gamma2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Author:	Lu, Xin-Sui\|Sun, Wei\|Ge, Chun-Yan\|Zhang, Wen-Zhong\|Fan, Yue-Zu
PMID:	23588386

11.
Journal:	Int J Oncol. 2013 Feb;42(2):690-8.
Title:	Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma.
Author:	Yang, Wei\|Wang, Xiaoyuan\|Zheng, Wei\|Li, Kedong\|Liu, Haofeng\|Sun, Yueming
PMID:	23254774

12.
Journal:	Ann Surg Oncol. 2013 May;20(5):1470-81.
Title:	Regional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression.
Author:	Butte, Jean M\|Torres, Javiera\|Veras, Emanuela F\|Matsuo, Kenichi\|Gonen, Mithat\|D'Angelica, Michael I\|Waugh, Enrique\|Meneses, Manuel\|Inayama, Yoshiyaki\|Fong, Yuman\|Dematteo, Ronald P\|De La Fuente, Hernan\|Endo, Itaru\|Klimstra, David S\|Jarnagin, William R
PMID:	23212762

13.
Journal:	BMC Cancer. 2014 Mar 15;14:193.
Title:	Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5gamma2 signaling pathway.
Author:	Zhang, Jing-Tao\|Sun, Wei\|Zhang, Wen-Zhong\|Ge, Chun-Yan\|Liu, Zhong-Yan\|Zhao, Ze-Ming\|Lu, Xing-Sui\|Fan, Yue-Zu
PMID:	24628713

14.
Journal:	Oncotarget. 2014 Feb 28;5(4):894-900.
Title:	Role of aberrant PI3K pathway activation in gallbladder tumorigenesis.
Author:	Lunardi, Andrea\|Webster, Kaitlyn A\|Papa, Antonella\|Padmani, Bhavik\|Clohessy, John G\|Bronson, Roderick T\|Pandolfi, Pier Paolo
PMID:	24658595

15.
Journal:	Oncotarget. 2014 May 15;5(9):2372-89.
Title:	Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma.
Author:	Chen, Ming-Huang\|Chiang, Kun-Chun\|Cheng, Chi-Tung\|Huang, Shih-Chiang\|Chen, Yeng-Yang\|Chen, Tsung-Wen\|Yeh, Ta-Sen\|Jan, Yi-Yin\|Wang, Hsi-Ming\|Weng, Jiang-Jie\|Chang, Peter Mu-Hsin\|Liu, Chun-Yu\|Li, Chung-Pin\|Chao, Yee\|Chen, Ming-Han\|Huang, Chi-Ying F\|Yeh, Chu
PMID:	24796583

16.
Journal:	Cancer Treat Rev. 2015 Mar;41(3):222-34.
Title:	Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy.
Author:	Bizama, Carolina\|Garcia, Patricia\|Espinoza, Jaime A\|Weber, Helga\|Leal, Pamela\|Nervi, Bruno\|Roa, Juan Carlos
PMID:	25639632

17.
Journal:	Tumour Biol. 2015 Nov;36(11):8367-77.
Title:	Gab1 regulates proliferation and migration through the PI3K/Akt signaling pathway in intrahepatic cholangiocarcinoma.
Author:	Sang, Haiquan\|Li, Tingting\|Li, Hangyu\|Liu, Jingang
PMID:	26014518

18.
Journal:	Diagn Pathol. 2015 Aug 21;10:148.
Title:	Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer.
Author:	Roa, Ivan\|de Toro, Gonzalo\|Fernandez, Fernanda\|Game, Anakaren\|Munoz, Sergio\|de Aretxabala, Xabier\|Javle, Milind
PMID:	26294099

19.
Journal:	Int J Clin Exp Pathol. 2015 Nov 1;8(11):14028-33. eCollection 2015.
Title:	Modulatory role of garlicin in migration and invasion of intrahepatic cholangiocarcinoma via PI3K/AKT pathway.
Author:	Xie, Kun\|Nian, Jianze\|Zhu, Xingyang\|Geng, Xiaoping\|Liu, Fubao
PMID:	26823715

20.
Journal:	Gut. 2016 Oct;65(10):1765-75.
Title:	LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Author:	Scarzello, Anthony J\|Jiang, Qun\|Back, Timothy\|Dang, Hien\|Hodge, Deborah\|Hanson, Charlotte\|Subleski, Jeffrey\|Weiss, Jonathan M\|Stauffer, Jimmy K\|Chaisaingmongkol, Jitti\|Rabibhadana, Siritida\|Ruchirawat, Mathuros\|Ortaldo, John\|Wang, Xin Wei\|Norris, Paula S\|
PMID:	26206664

21.
Journal:	Am J Transl Res. 2016 Oct 15;8(10):4068-4081. eCollection 2016.
Title:	Upregulation of long non-coding RNA LINC00152 by SP1 contributes to gallbladder cancer cell growth and tumor metastasis via PI3K/AKT pathway.
Author:	Cai, Qiang\|Wang, Zhen-Qiang\|Wang, Shou-Hua\|Li, Chen\|Zhu, Zheng-Gang\|Quan, Zhi-Wei\|Zhang, Wen-Jie
PMID:	27829993

22.
Journal:	Oncotarget. 2016 Nov 15;7(46):75210-75220.
Title:	Protein tyrosine phosphatase PTP4A1 promotes proliferation and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma via the PI3K/AKT pathway.
Author:	Liu, Long-Zi\|He, Yi-Zhou\|Dong, Ping-Ping\|Ma, Li-Jie\|Wang, Zhi-Chao\|Liu, Xin-Yang\|Duan, Meng\|Yang, Liu-Xiao\|Shi, Jie-Yi\|Zhou, Jian\|Fan, Jia\|Gao, Qiang\|Wang, Xiao-Ying
PMID:	27655691

23.
Journal:	Onco Targets Ther. 2016 Aug 24;9:5297-305.
Title:	Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Author:	Zhu, Lei\|Huang, Feizhou\|Deng, Gang\|Nie, Wanpin\|Huang, Wei\|Xu, Hongbo\|Zheng, Shaopeng\|Yi, Zhongjie\|Wan, Tao
PMID:	27601921

24.
Journal:	Cancer Lett. 2016 Jun 28;376(1):197-198.
Title:	Corrigendum to .
Author:	Li, ZhiZhen\|Chen, YuanYuan\|Wang, XuAn\|Zhang, HongChen\|Zhang, Yijian\|Gao, YaoHui\|Weng, Mingzhe\|Wang, Lei\|Liang, HaiBin\|Li, MaoLan\|Zhang, Fei\|Zhao, Shuai\|Liu, Shibo\|Cao, Yang\|Shu, Yijun\|Bao, Runfa\|Zhou, Jian\|Liu, Xiyong\|Yan, Yun\|Zhen, Lei\|Dong, Qian\|Liu, Yi
PMID:	27125425

25.
Journal:	Cancer Lett. 2016 May 28;375(1):179-89.
Title:	A novel PI3K/AKT signaling axis mediates Nectin-4-induced gallbladder cancer cell proliferation, metastasis and tumor growth.
Author:	Zhang, Yijian\|Liu, Shibo\|Wang, Lei\|Wu, Yaoshi\|Hao, Jiaqi\|Wang, Zheng\|Lu, Wei\|Wang, Xu-An\|Zhang, Fei\|Cao, Yang\|Liang, Haibin\|Li, Huaifeng\|Ye, Yuanyuan\|Ma, Qiang\|Zhao, Shuai\|Shu, Yijun\|Bao, Runfa\|Jiang, Lin\|Hu, Yunping\|Zhou, Jian\|Chen, Lei\|Liu, Yingbin
PMID:	26949052

26.
Journal:	J Mol Diagn. 2016 May;18(3):388-394.
Title:	Somatic Mutations of PI3K in Early and Advanced Gallbladder Cancer: Additional Options for an Orphan Cancer.
Author:	Roa, Ivan\|Garcia, Hernan\|Game, Anakaren\|de Toro, Gonzalo\|de Aretxabala, Xabier\|Javle, Milind
PMID:	26947513

27.
Journal:	Mol Cancer Ther. 2017 Feb;16(2):344-356.
Title:	Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities.
Author:	Talbert, Erin E\|Yang, Jennifer\|Mace, Thomas A\|Farren, Matthew R\|Farris, Alton B\|Young, Gregory S\|Elnaggar, Omar\|Che, Zheng\|Timmers, Cynthia D\|Rajasekera, Priyani\|Maskarinec, Jennifer M\|Bloomston, Mark\|Bekaii-Saab, Tanios\|Guttridge, Denis C\|Lesinski, Grego
PMID:	27811010

28.
Journal:	Expert Opin Ther Targets. 2017 May;21(5):485-498.
Title:	Signaling pathways as therapeutic targets in biliary tract cancer.
Author:	Yang, Jennifer\|Farren, Matthew R\|Ahn, Daniel\|Bekaii-Saab, Tanios\|Lesinski, Gregory B
PMID:	28282502

29.
Journal:	Oncotarget. 2017 Jul 18;8(29):47052-47063.
Title:	TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.
Author:	Li, Xinxing\|Teng, Shifeng\|Zhang, Yanyan\|Zhang, Weigang\|Zhang, Xianwen\|Xu, Kai\|Yao, Houshan\|Yao, Jun\|Wang, Haolu\|Liang, Xiaowen\|Hu, Zhiqian
PMID:	28423362

30.
Journal:	Int J Biol Sci. 2017 Jun 1;13(6):782-793.
Title:	Dioscin Induces Gallbladder Cancer Apoptosis by Inhibiting ROS-Mediated PI3K/AKT Signalling.
Author:	Song, Xiaoling\|Wang, Zheng\|Liang, Haibin\|Zhang, Wenjie\|Ye, Yuanyuan\|Li, HuaiFeng\|Hu, Yunping\|Zhang, Yijian\|Weng, Hao\|Lu, Jianhua\|Wang, Xuefeng\|Li, Maolan\|Liu, Yingbin\|Gu, Jun
PMID:	28656003

31.
Journal:	Int J Oncol. 2017 Sep;51(3):823-831.
Title:	Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway.
Author:	Hao, Jiaqi\|Yang, Ziyi\|Wang, Lei\|Zhang, Yijian\|Shu, Yijun\|Jiang, Lin\|Hu, Yunping\|Lv, Wenjie\|Dong, Ping\|Liu, Yingbin
PMID:	28766687

32.
Journal:	Int J Mol Med. 2017 Oct;40(4):1143-1151.
Title:	Osthole induces apoptosis and suppresses proliferation via the PI3K/Akt pathway in intrahepatic cholangiocarcinoma.
Author:	Zhu, Xingyang\|Song, Xiaoling\|Xie, Kun\|Zhang, Xue\|He, Wei\|Liu, Fubao
PMID:	28902342

33.
Journal:	Cytotechnology. 2018 Feb;70(1):83-94.
Title:	Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Author:	Qian, Liqiang\|Li, Xiaqin\|Ye, Penghui\|Wang, Gang\|Dai, Wei\|Liu, Yan\|Gao, Quangen\|Shen, Genhai
PMID:	29170841

34.
Journal:	Int J Biochem Cell Biol. 2018 Apr;97:16-27.
Title:	STYK1 promotes cancer cell proliferation and malignant transformation by activating PI3K-AKT pathway in gallbladder carcinoma.
Author:	Hu, Yun-Ping\|Wu, Zeng-Bin\|Jiang, Lin\|Jin, Yun-Peng\|Li, Huai-Feng\|Zhang, Yi-Jian\|Ma, Qiang\|Ye, Yuan-Yuan\|Wang, Zheng\|Liu, Yong-Chen\|Chen, Hong-Zhuan\|Liu, Ying-Bin
PMID:	29413947

35.
Journal:	Cell Death Dis. 2018 Feb 7;9(2):182.
Title:	miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma.
Author:	Jin, Yun-Peng\|Hu, Yun-Ping\|Wu, Xiang-Song\|Wu, Yao-Shi\|Ye, Yuan-Yuan\|Li, Huai-Feng\|Liu, Yong-Chen\|Jiang, Lin\|Liu, Fa-Tao\|Zhang, Yi-Jian\|Hao, Ya-Juan\|Liu, Xi-Yong\|Liu, Ying-Bin
PMID:	29416013

36.
Journal:	Jpn J Clin Oncol. 2018 Apr 1;48(4):396-399.
Title:	PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay.
Author:	Sakamoto, Yasunari\|Yamagishi, Seri\|Tanizawa, Yoshinori\|Tajimi, Masaomi\|Okusaka, Takuji\|Ojima, Hidenori
PMID:	29474549

37.
Journal:	Biomed Pharmacother. 2018 Jul;103:1272-1278.
Title:	Knockdown of TRIM31 suppresses proliferation and invasion of gallbladder cancer cells by down-regulating MMP2/9 through the PI3K/Akt signaling pathway.
Author:	Li, Hui\|Zhang, Yu\|Hai, Jun\|Wang, Jixin\|Zhao, Bei\|Du, Lixue\|Geng, Xilin
PMID:	29864908

38.
Journal:	Cell Oncol (Dordr). 2018 Oct 1. pii: 10.1007/s13402-018-0410-8.
Title:	CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer.
Author:	Zhou, Zhenyu\|Peng, Yaorong\|Wu, Xiaoying\|Meng, Shiyu\|Yu, Wei\|Zhao, Jinghua\|Zhang, Heyun\|Wang, Jie\|Li, Wenbin
PMID:	30276551

39.
Journal:	J Cell Physiol. 2018 Oct 28.
Title:	Targeting phosphoinositide-3-kinase pathway in biliary tract cancers: A remedial route?
Author:	Kaavya, Jayaramayya\|Mahalaxmi, Iyer\|Devi, Subramaniam Mohana\|Santhy, K S\|Balachandar, Vellingiri
PMID:	30370571