Primary Site >> Colorectal Cancer
Gene >> PIK3CB
| 1. | |||||||||||
| Journal: | J Biol Chem. 1998 Nov 27;273(48):32016-22. | ||||||||||
| Title: | A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon. | ||||||||||
| Author: | Graness, A|Adomeit, A|Heinze, R|Wetzker, R|Liebmann, C | ||||||||||
| PMID: | 9822674 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2000 Oct 19;19(44):5083-90. | ||||||||||
| Title: | A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells. | ||||||||||
| Author: | Benistant, C|Chapuis, H|Roche, S | ||||||||||
| PMID: | 11042696 | ||||||||||
| 3. | |||||||||||
| Journal: | Surgery. 2006 Aug;140(2):322-9. | ||||||||||
| Title: | TGF-beta inhibits Akt-induced transformation in intestinal epithelial cells. | ||||||||||
| Author: | Cao, Yanna|Deng, Chunyan|Townsend, Courtney M Jr|Ko, Tien C | ||||||||||
| PMID: | 16904986 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2007 Aug 1;67(15):7266-74. | ||||||||||
| Title: | Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B. | ||||||||||
| Author: | Rengifo-Cam, William|Umar, Shahid|Sarkar, Shubhashish|Singh, Pomila | ||||||||||
| PMID: | 17671195 | ||||||||||
| 5. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13057-62. | ||||||||||
| Title: | PTEN-deficient cancers depend on PIK3CB. | ||||||||||
| Author: | Wee, Susan|Wiederschain, Dmitri|Maira, Sauveur-Michel|Loo, Alice|Miller, Christine|deBeaumont, Rosalie|Stegmeier, Frank|Yao, Yung-Mae|Lengauer, Christoph | ||||||||||
| PMID: | 18755892 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2008 Sep;1138:204-13. | ||||||||||
| Title: | The transforming functions of PI3-kinase-gamma are linked to disruption of intercellular adhesion and promotion of cancer cell invasion. | ||||||||||
| Author: | Attoub, Samir|De Wever, Olivier|Bruyneel, Eric|Mareel, Marc|Gespach, Christian | ||||||||||
| PMID: | 18837901 | ||||||||||
| 7. | |||||||||||
| Journal: | Mediators Inflamm. 2010;2010. | ||||||||||
| Title: | The p110alpha and p110beta isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells. | ||||||||||
| Author: | Ivison, Sabine M|Khan, Mohammed A S|Graham, Nicholas R|Shobab, Leila A|Yao, Yu|Kifayet, Arnawaz|Sly, Laura M|Steiner, Theodore S | ||||||||||
| PMID: | 20953381 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Cancer Ther. 2011 Aug;10(8):1394-406. | ||||||||||
| Title: | Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. | ||||||||||
| Author: | Bhagwat, Shripad V|Gokhale, Prafulla C|Crew, Andrew P|Cooke, Andy|Yao, Yan|Mantis, Christine|Kahler, Jennifer|Workman, Jennifer|Bittner, Mark|Dudkin, Lorina|Epstein, David M|Gibson, Neil W|Wild, Robert|Arnold, Lee D|Houghton, Peter J|Pachter, Jonathan A | ||||||||||
| PMID: | 21673091 | ||||||||||
| 9. | |||||||||||
| Journal: | Cell Biochem Biophys. 2012 Jan;62(1):47-54. | ||||||||||
| Title: | Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer. | ||||||||||
| Author: | Cui, Binbin|Tao, Ji|Yang, Yanmei | ||||||||||
| PMID: | 21910030 | ||||||||||
| 10. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):280-286. | ||||||||||
| Title: | Down-regulation of p110beta expression increases chemosensitivity of colon cancer cell lines to oxaliplatin. | ||||||||||
| Author: | Liu, Weicheng|Wang, Guihua|Cao, Xiaonian|Luo, Xuelai|Li, Zhaoming|Deng, Yu|Li, Xiaolan|Wang, Shijia|Liu, Mengfei|Hu, Junbo|Wang, Jing | ||||||||||
| PMID: | 22528234 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2013 May 14;8(5):e63298. | ||||||||||
| Title: | TLR4 activates the beta-catenin pathway to cause intestinal neoplasia. | ||||||||||
| Author: | Santaolalla, Rebeca|Sussman, Daniel A|Ruiz, Jose R|Davies, Julie M|Pastorini, Cristhine|Espana, Cecilia L|Sotolongo, John|Burlingame, Oname|Bejarano, Pablo A|Philip, Sakhi|Ahmed, Mansoor M|Ko, Jeffrey|Dirisina, Ramanarao|Barrett, Terrence A|Shang, Limin|L | ||||||||||
| PMID: | 23691015 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncotarget. 2014 May 30;5(10):2999-3011. | ||||||||||
| Title: | WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear beta-Catenin depend on active PI3K signaling. | ||||||||||
| Author: | Ormanns, Steffen|Neumann, Jens|Horst, David|Kirchner, Thomas|Jung, Andreas | ||||||||||
| PMID: | 24930890 | ||||||||||
| 13. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Nov 21;20(43):16258-67. | ||||||||||
| Title: | Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma. | ||||||||||
| Author: | Yu, Wei-Dong|Peng, Yi-Fan|Pan, Hong-Da|Wang, Lin|Li, Kun|Gu, Jin | ||||||||||
| PMID: | 25473181 | ||||||||||
| 14. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2014 Oct 15;7(11):8295-303. eCollection 2014. | ||||||||||
| Title: | PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma. | ||||||||||
| Author: | Wen, Feifei|He, Shuang|Sun, Chenbo|Li, Tangyue|Wu, Shuhua | ||||||||||
| PMID: | 25550888 | ||||||||||
| 15. | |||||||||||
| Journal: | Hum Pathol. 2015 May;46(5):753-60. | ||||||||||
| Title: | Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers. | ||||||||||
| Author: | Choi, Mi Ryoung|Yoo, Nam Jin|An, Chang Hyeok|Lee, Sug Hyung | ||||||||||
| PMID: | 25776026 | ||||||||||
| 16. | |||||||||||
| Journal: | Tumour Biol. 2016 Jan;37(1):583-90. | ||||||||||
| Title: | Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness. | ||||||||||
| Author: | Klahan, Sukhontip|Huang, Chi-Cheng|Chien, Shu-Chen|Wu, Mei-Shin|Wong, Henry Sung-Ching|Huang, Chien-Yu|Chang, Wei-Chiao|Wei, Po-Li | ||||||||||
| PMID: | 26232912 | ||||||||||
| 17. | |||||||||||
| Journal: | Tumour Biol. 2016 Jul;37(7):8799-809. | ||||||||||
| Title: | PIK3CA and PIK3CB silencing by RNAi reverse MDR and inhibit tumorigenic properties in human colorectal carcinoma. | ||||||||||
| Author: | Wu, Shuhua|Wen, Feifei|Li, Yangyang|Gao, Xiangqian|He, Shuang|Liu, Mengyao|Zhang, Xiangzhi|Tian, Dong | ||||||||||
| PMID: | 26747178 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 6;7(49):81156-81171. | ||||||||||
| Title: | Gankyrin sustains PI3K/GSK-3beta/beta-catenin signal activation and promotes colorectal cancer aggressiveness and progression. | ||||||||||
| Author: | He, Feng|Chen, Huacui|Yang, Ping|Wu, Qianlong|Zhang, Tong|Wang, Chengxing|Wei, Jianchang|Chen, Zhuanpeng|Hu, He|Li, Wanglin|Cao, Jie | ||||||||||
| PMID: | 27835604 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2017 Jan 20;12(1):e0170551. | ||||||||||
| Title: | Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. | ||||||||||
| Author: | Soo, Hsien-Chuen|Chung, Felicia Fei-Lei|Lim, Kuan-Hon|Yap, Veronica Alicia|Bradshaw, Tracey D|Hii, Ling-Wei|Tan, Si-Hoey|See, Sze-Jia|Tan, Yuen-Fen|Leong, Chee-Onn|Mai, Chun-Wai | ||||||||||
| PMID: | 28107519 | ||||||||||
| 20. | |||||||||||
| Journal: | Clin Cancer Res. 2017 Dec 1;23(23):7340-7350. | ||||||||||
| Title: | Phospholipase D1 Inhibition Linked to Upregulation of ICAT Blocks Colorectal Cancer Growth Hyperactivated by Wnt/beta-Catenin and PI3K/Akt Signaling. | ||||||||||
| Author: | Kang, Dong Woo|Lee, Bo Hui|Suh, Young-Ah|Choi, Yong-Seok|Jang, Se Jin|Kim, Yong Man|Choi, Kang-Yell|Min, Do Sik | ||||||||||
| PMID: | 28939743 | ||||||||||