Primary Site >> Stomach Cancer
Gene >> PIK3CA
| 1. | |||||||||||
| Journal: | Int J Cancer. 2003 Apr 10;104(3):318-27. | ||||||||||
| Title: | Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma. | ||||||||||
| Author: | Byun, Do-Sun|Cho, Kyucheol|Ryu, Byung-Kyu|Lee, Min-Goo|Park, Jae-Il|Chae, Kwon-Seok|Kim, Hyo-Jong|Chi, Sung-Gil | ||||||||||
| PMID: | 12569555 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2004 Aug 1;64(15):5048-50. | ||||||||||
| Title: | Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. | ||||||||||
| Author: | Broderick, Daniel K|Di, Chunhui|Parrett, Timothy J|Samuels, Yardena R|Cummins, Jordan M|McLendon, Roger E|Fults, Daniel W|Velculescu, Victor E|Bigner, Darell D|Yan, Hai | ||||||||||
| PMID: | 15289301 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2005 Feb 17;24(8):1477-80. | ||||||||||
| Title: | PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. | ||||||||||
| Author: | Lee, Jong Woo|Soung, Young Hwa|Kim, Su Young|Lee, Hae Woo|Park, Won Sang|Nam, Suk Woo|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 15608678 | ||||||||||
| 4. | |||||||||||
| Journal: | BMC Cancer. 2005 Mar 23;5:29. | ||||||||||
| Title: | Mutations of PIK3CA in gastric adenocarcinoma. | ||||||||||
| Author: | Li, Vivian Sze Wing|Wong, Chi Wai|Chan, Tsun Leung|Chan, Agnes Sze Wah|Zhao, Wei|Chu, Kent-Man|So, Samuel|Chen, Xin|Yuen, Siu Tsan|Leung, Suet Yi | ||||||||||
| PMID: | 15784156 | ||||||||||
| 5. | |||||||||||
| Journal: | Eur J Cancer. 2005 Jul;41(11):1649-54. | ||||||||||
| Title: | The prevalence of PIK3CA mutations in gastric and colon cancer. | ||||||||||
| Author: | Velho, Sergia|Oliveira, Carla|Ferreira, Ana|Ferreira, Antonio Carlos|Suriano, Gianpaolo|Schwartz, Simo Jr|Duval, Alex|Carneiro, Fatima|Machado, Jose Carlos|Hamelin, Richard|Seruca, Raquel | ||||||||||
| PMID: | 15994075 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Exp Metastasis. 2005;22(2):137-47. | ||||||||||
| Title: | Establishment and characterization of three novel human gastric cancer cell lines with differentiated intestinal phenotype derived from liver metastasis. | ||||||||||
| Author: | Nakanishi, Hayao|Yasui, Kenzo|Ikehara, Yuzuru|Yokoyama, Hiroyuki|Munesue, Seiichi|Kodera, Yasuhiro|Tatematsu, Masae | ||||||||||
| PMID: | 16086234 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Oncol. 2005 Dec;27(6):1677-83. | ||||||||||
| Title: | Epithelial-mesenchymal transition in gastric cancer (Review). | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 16273224 | ||||||||||
| 8. | |||||||||||
| Journal: | APMIS. 2005 Oct;113(10):683-7. | ||||||||||
| Title: | ERBB2 kinase domain mutation in a gastric cancer metastasis. | ||||||||||
| Author: | Lee, Jong Woo|Soung, Young Hwa|Kim, Su Young|Park, Won Sang|Nam, Suk Woo|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 16309427 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2006 Mar 15;118(6):1426-9. | ||||||||||
| Title: | Somatic mutations of the ERBB4 kinase domain in human cancers. | ||||||||||
| Author: | Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Wang, Young Pil|Jo, Keon Hyun|Moon, Seok Whan|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 16187281 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Cancer. 2006 Jun 15;118(12):2965-72. | ||||||||||
| Title: | Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation. | ||||||||||
| Author: | Xue, Yan|Bi, Feng|Zhang, Xueyong|Zhang, Siyuan|Pan, Yanglin|Liu, Na|Shi, Yongquan|Yao, Xuebiao|Zheng, Yi|Fan, Daiming | ||||||||||
| PMID: | 16395716 | ||||||||||
| 11. | |||||||||||
| Journal: | Clin Cancer Res. 2006 Jan 1;12(1):57-61. | ||||||||||
| Title: | Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. | ||||||||||
| Author: | Lee, Jong Woo|Soung, Young Hwa|Seo, Si Hyung|Kim, Su Young|Park, Cho Hyun|Wang, Young Pil|Park, Kyeongmee|Nam, Suk Woo|Park, Won Sang|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 16397024 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncology. 2006;70(4):285-9. Epub 2006 Oct 16. | ||||||||||
| Title: | Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas. | ||||||||||
| Author: | Soung, Young Hwa|Lee, Jong Woo|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 17047397 | ||||||||||
| 13. | |||||||||||
| Journal: | Semin Diagn Pathol. 2008 Nov;25(4):274-87. | ||||||||||
| Title: | Molecular targets and biological modifiers in gastric cancer. | ||||||||||
| Author: | Carneiro, Fatima|Oliveira, Carla|Leite, Marina|Seruca, Raquel | ||||||||||
| PMID: | 19013893 | ||||||||||
| 14. | |||||||||||
| Journal: | World J Gastroenterol. 2009 Nov 28;15(44):5579-85. | ||||||||||
| Title: | Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen. | ||||||||||
| Author: | Yamaoka, Satoshi|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Taniguchi, Hiroaki|Adachi, Yasushi|Sasaki, Shigeru|Arimura, Yoshiaki|Imai, Kohzoh|Shinomura, Yasuhisa | ||||||||||
| PMID: | 19938198 | ||||||||||
| 15. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2010 Apr 16;29:32. | ||||||||||
| Title: | The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type. | ||||||||||
| Author: | Barbi, Stefano|Cataldo, Ivana|De Manzoni, Giovanni|Bersani, Samantha|Lamba, Simona|Mattuzzi, Silvia|Bardelli, Alberto|Scarpa, Aldo | ||||||||||
| PMID: | 20398348 | ||||||||||
| 16. | |||||||||||
| Journal: | World J Gastroenterol. 2010 Oct 21;16(39):4986-91. | ||||||||||
| Title: | Up-regulation of PIK3CA promotes metastasis in gastric carcinoma. | ||||||||||
| Author: | Liu, Ji-Fang|Zhou, Xin-Ke|Chen, Jin-Hui|Yi, Gao|Chen, He-Ge|Ba, Ming-Chen|Lin, Sheng-Qu|Qi, Yan-Chao | ||||||||||
| PMID: | 20954287 | ||||||||||
| 17. | |||||||||||
| Journal: | Eur J Cancer. 2011 Feb;47(3):443-51. | ||||||||||
| Title: | Oncogenic mutations in gastric cancer with microsatellite instability. | ||||||||||
| Author: | Corso, Giovanni|Velho, Sergia|Paredes, Joana|Pedrazzani, Corrado|Martins, Diana|Milanezi, Fernanda|Pascale, Valeria|Vindigni, Carla|Pinheiro, Hugo|Leite, Marina|Marrelli, Daniele|Sousa, Sonia|Carneiro, Fatima|Oliveira, Carla|Roviello, Franco|Seruca, Raque | ||||||||||
| PMID: | 20937558 | ||||||||||
| 18. | |||||||||||
| Journal: | Tumour Biol. 2011 Oct;32(5):913-20. | ||||||||||
| Title: | Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue type. | ||||||||||
| Author: | Zhai, Linzhu|Zhao, Yuanyuan|Ye, Sheng|Huang, He|Tian, Ying|Wu, Qiuliang|Lin, Hanliang|Lin, Tongyu | ||||||||||
| PMID: | 21660567 | ||||||||||
| 19. | |||||||||||
| Journal: | World J Gastroenterol. 2011 Aug 28;17(32):3700-8. | ||||||||||
| Title: | RNAi knockdown of PIK3CA preferentially inhibits invasion of mutant PIK3CA cells. | ||||||||||
| Author: | Zhou, Xin-Ke|Tang, Sheng-Song|Yi, Gao|Hou, Min|Chen, Jin-Hui|Yang, Bo|Liu, Ji-Fang|He, Zhi-Min | ||||||||||
| PMID: | 21990951 | ||||||||||
| 20. | |||||||||||
| Journal: | BMC Cancer. 2012 Feb 1;12:50. | ||||||||||
| Title: | Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer. | ||||||||||
| Author: | Shi, Jing|Yao, Demao|Liu, Wei|Wang, Na|Lv, Hongjun|Zhang, Guanjun|Ji, Meiju|Xu, Li|He, Nongyue|Shi, Bingyin|Hou, Peng | ||||||||||
| PMID: | 22292935 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Jan 1;13(1):34-42. | ||||||||||
| Title: | Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells. | ||||||||||
| Author: | Bhattacharya, Bhaskar|Akram, Mohamed|Balasubramanian, Indirikumar|Tam, Kimberley K Y|Koh, King X|Yee, Mei Q|Soong, Richie | ||||||||||
| PMID: | 22336586 | ||||||||||
| 22. | |||||||||||
| Journal: | J Biol Chem. 2012 Apr 6;287(15):12132-41. | ||||||||||
| Title: | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells. | ||||||||||
| Author: | Chen, Guang|Chen, Si-Meng|Wang, Xiang|Ding, Xiao-Fei|Ding, Jian|Meng, Ling-Hua | ||||||||||
| PMID: | 22337890 | ||||||||||
| 23. | |||||||||||
| Journal: | Nat Genet. 2012 May;44(5):570-4. | ||||||||||
| Title: | Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. | ||||||||||
| Author: | Zang, Zhi Jiang|Cutcutache, Ioana|Poon, Song Ling|Zhang, Shen Li|McPherson, John R|Tao, Jiong|Rajasegaran, Vikneswari|Heng, Hong Lee|Deng, Niantao|Gan, Anna|Lim, Kiat Hon|Ong, Choon Kiat|Huang, DaChuan|Chin, Sze Yung|Tan, Iain Beehuat|Ng, Cedric Chuan You | ||||||||||
| PMID: | 22484628 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15. | ||||||||||
| Title: | Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines. | ||||||||||
| Author: | Mueller, Annett|Bachmann, Erika|Linnig, Monika|Khillimberger, Katrin|Schimanski, Carl Christoph|Galle, Peter R|Moehler, Markus | ||||||||||
| PMID: | 22543857 | ||||||||||
| 25. | |||||||||||
| Journal: | Pathol Int. 2012 Jul;62(7):477-84. | ||||||||||
| Title: | Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization. | ||||||||||
| Author: | Kiyose, Shin-ichiro|Nagura, Kiyoko|Tao, Hong|Igarashi, Hisaki|Yamada, Hidetaka|Goto, Masanori|Maeda, Matsuyoshi|Kurabe, Nobuya|Suzuki, Masaya|Tsuboi, Masaru|Kahyo, Tomoaki|Shinmura, Kazuya|Hattori, Naohiko|Sugimura, Haruhiko | ||||||||||
| PMID: | 22691185 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2012;7(6):e38892. | ||||||||||
| Title: | High-throughput mutation profiling identifies frequent somatic mutations in advanced gastric adenocarcinoma. | ||||||||||
| Author: | Lee, Jeeyun|van Hummelen, Paul|Go, Christina|Palescandolo, Emanuele|Jang, Jiryeon|Park, Ha Young|Kang, So Young|Park, Joon Oh|Kang, Won Ki|MacConaill, Laura|Kim, Kyoung-Mee | ||||||||||
| PMID: | 22723903 | ||||||||||
| 27. | |||||||||||
| Journal: | J Transl Med. 2012 Aug 30;10:180. | ||||||||||
| Title: | Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models. | ||||||||||
| Author: | Wu, Xianhua|Zhang, Jingchuan|Zhen, Ruheng|Lv, Jing|Zheng, Li|Su, Xinying|Zhu, Guanshan|Gavine, Paul R|Xu, Songtao|Lu, Shaohua|Hou, Jun|Liu, Yalan|Xu, Chen|Tan, Yunshan|Xie, Liang|Yin, Xiaolu|He, Deming|Ji, Qunsheng|Hou, Yingyong|Ge, Di | ||||||||||
| PMID: | 22935382 | ||||||||||
| 28. | |||||||||||
| Journal: | Nihon Rinsho. 2012 Oct;70(10):1705-14. | ||||||||||
| Title: | [Genetic and epigenetic alterations in gastric carcinogenesis]. | ||||||||||
| Author: | Ushijima, Toshikazu|Yoshida, Satoshi | ||||||||||
| PMID: | 23198549 | ||||||||||
| 29. | |||||||||||
| Journal: | World J Gastroenterol. 2012 Dec 7;18(45):6577-86. | ||||||||||
| Title: | Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer. | ||||||||||
| Author: | Sukawa, Yasutaka|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Kunimoto, Hiroaki|Suzuki, Hiromu|Adachi, Yasushi|Nakazawa, Mayumi|Nobuoka, Takayuki|Kawayama, Mariko|Mikami, Masashi|Matsuno, Takashi|Hasegawa, Tadashi|Hirata, Koichi|Imai, Kohzoh|Shinomura, Yasuhisa | ||||||||||
| PMID: | 23236232 | ||||||||||
| 30. | |||||||||||
| Journal: | Ann Oncol. 2013 Mar;24(3):693-701. | ||||||||||
| Title: | A clinical-biological risk stratification model for resected gastric cancer: prognostic impact of Her2, Fhit, and APC expression status. | ||||||||||
| Author: | Bria, E|De Manzoni, G|Beghelli, S|Tomezzoli, A|Barbi, S|Di Gregorio, C|Scardoni, M|Amato, E|Frizziero, M|Sperduti, I|Corbo, V|Brunelli, M|Bersani, S|Tortora, G|Scarpa, A | ||||||||||
| PMID: | 23131390 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Lett. 2013 Mar 1;330(1):33-40. | ||||||||||
| Title: | Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers. | ||||||||||
| Author: | Kim, Jeong Goo|Takeshima, Hideyuki|Niwa, Tohru|Rehnberg, Emil|Shigematsu, Yasuyuki|Yoda, Yukie|Yamashita, Satoshi|Kushima, Ryoji|Maekita, Takao|Ichinose, Masao|Katai, Hitoshi|Park, Won Sang|Hong, Young Seon|Park, Cho Hyun|Ushijima, Toshikazu | ||||||||||
| PMID: | 23196062 | ||||||||||
| 32. | |||||||||||
| Journal: | J Pathol. 2013 Mar;229(4):621-9. | ||||||||||
| Title: | An alpha-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer. | ||||||||||
| Author: | Majewski, Ian J|Kluijt, Irma|Cats, Annemieke|Scerri, Thomas S|de Jong, Daphne|Kluin, Roelof J C|Hansford, Samantha|Hogervorst, Frans B L|Bosma, Astrid J|Hofland, Ingrid|Winter, Marcel|Huntsman, David|Jonkers, Jos|Bahlo, Melanie|Bernards, Rene | ||||||||||
| PMID: | 23208944 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Feb;12(2):151-61. | ||||||||||
| Title: | VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. | ||||||||||
| Author: | Hart, Stefan|Novotny-Diermayr, Veronica|Goh, Kee Chuan|Williams, Meredith|Tan, Yong Cheng|Ong, Lai Chun|Cheong, Albert|Ng, Bee Kheng|Amalini, Chithra|Madan, Babita|Nagaraj, Harish|Jayaraman, Ramesh|Pasha, Khalid M|Ethirajulu, Kantharaj|Chng, Wee Joo|Musta | ||||||||||
| PMID: | 23270925 | ||||||||||
| 34. | |||||||||||
| Journal: | J Surg Oncol. 2013 Aug;108(2):113-20. | ||||||||||
| Title: | Molecular changes in the phosphatidylinositide 3-kinase (PI3K) pathway are common in gastric cancer. | ||||||||||
| Author: | Tran, Thang N|Brettingham-Moore, Kate|Duong, Cuong P|Mitchell, Catherine|Clemons, Nicholas J|Phillips, Wayne A | ||||||||||
| PMID: | 23813545 | ||||||||||
| 35. | |||||||||||
| Journal: | Discov Med. 2013 Jun;15(85):333-41. | ||||||||||
| Title: | Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part I: Targeting receptor tyrosine kinase gene amplification. | ||||||||||
| Author: | Lee, Jeeyun|Ou, Sai-Hong Ignatius | ||||||||||
| PMID: | 23819947 | ||||||||||
| 36. | |||||||||||
| Journal: | Diagn Mol Pathol. 2013 Sep;22(3):127-37. | ||||||||||
| Title: | Prognostic and putative predictive biomarkers of gastric cancer for personalized medicine. | ||||||||||
| Author: | Warneke, Viktoria S|Behrens, Hans-Michael|Haag, Jochen|Balschun, Katharina|Boger, Christine|Becker, Thomas|Ebert, Matthias P A|Lordick, Florian|Rocken, Christoph | ||||||||||
| PMID: | 23846438 | ||||||||||
| 37. | |||||||||||
| Journal: | Discov Med. 2013 Aug;16(86):7-14. | ||||||||||
| Title: | Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part II: Targeting gene mutations and gene amplifications and the angiogenesis pathway. | ||||||||||
| Author: | Lee, Jeeyun|Ou, Sai-Hong Ignatius | ||||||||||
| PMID: | 23911227 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Res. 2013 Oct 1;73(19):6013-23. | ||||||||||
| Title: | Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110alpha inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers. | ||||||||||
| Author: | Garrett, Joan T|Sutton, Cammie R|Kurupi, Richard|Bialucha, Carl Uli|Ettenberg, Seth A|Collins, Scott D|Sheng, Qing|Wallweber, Jerry|Defazio-Eli, Lisa|Arteaga, Carlos L | ||||||||||
| PMID: | 23918797 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Med. 2013 Jun;2(3):325-33. | ||||||||||
| Title: | Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma. | ||||||||||
| Author: | Werner, Dominique|Atmaca, Akin|Pauligk, Claudia|Pustowka, Anette|Jager, Elke|Al-Batran, Salah-Eddin | ||||||||||
| PMID: | 23930209 | ||||||||||
| 40. | |||||||||||
| Journal: | Clin Biochem. 2013 Oct 25. pii: S0009-9120(13)00488-8. | ||||||||||
| Title: | Concomitant PIK3CA amplification and RASSF1A or PAX6 hypermethylation predict worse survival in gastric cancer. | ||||||||||
| Author: | Yang, Qi|Shao, Yuan|Shi, Jing|Qu, Yiping|Wu, Kexia|Dang, Siwen|Shi, Bingyin|Hou, Peng | ||||||||||
| PMID: | 24513424 | ||||||||||
| 41. | |||||||||||
| Journal: | Int J Cancer. 2014 Mar 1;134(5):1232-8. | ||||||||||
| Title: | Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation. | ||||||||||
| Author: | Chong, Mei-Ling|Loh, Marie|Thakkar, Bhavin|Pang, Brendan|Iacopetta, Barry|Soong, Richie | ||||||||||
| PMID: | 23960014 | ||||||||||
| 42. | |||||||||||
| Journal: | J Surg Oncol. 2014 Mar;109(3):189-97. | ||||||||||
| Title: | TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer. | ||||||||||
| Author: | Shinmura, Kazuya|Kiyose, Shinichiro|Nagura, Kiyoko|Igarashi, Hisaki|Inoue, Yusuke|Nakamura, Satoki|Maeda, Matsuyoshi|Baba, Megumi|Konno, Hiroyuki|Sugimura, Haruhiko | ||||||||||
| PMID: | 24178904 | ||||||||||
| 43. | |||||||||||
| Journal: | Gastric Cancer. 2014;17(3):423-30. | ||||||||||
| Title: | The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway. | ||||||||||
| Author: | Park, Jinju|Ko, Young San|Yoon, Jiyeon|Kim, Min A|Park, Jong-Wan|Kim, Woo Ho|Choi, Youngsun|Kim, Ji Hun|Cheon, Younghee|Lee, Byung Lan | ||||||||||
| PMID: | 24202965 | ||||||||||
| 44. | |||||||||||
| Journal: | Digestion. 2014;89(1):12-7. | ||||||||||
| Title: | HER2 expression and PI3K-Akt pathway alterations in gastric cancer. | ||||||||||
| Author: | Sukawa, Yasutaka|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Ito, Miki|Igarashi, Hisayoshi|Naito, Takafumi|Mitsuhashi, Kei|Matsunaga, Yasutaka|Takahashi, Taiga|Mikami, Masashi|Adachi, Yasushi|Suzuki, Hiromu|Shinomura, Yasuhisa | ||||||||||
| PMID: | 24458107 | ||||||||||
| 45. | |||||||||||
| Journal: | Am J Surg Pathol. 2014 Jul;38(7):910-20. | ||||||||||
| Title: | SMARCB1 (INI1)-negative rhabdoid carcinomas of the gastrointestinal tract: clinicopathologic and molecular study of a highly aggressive variant with literature review. | ||||||||||
| Author: | Agaimy, Abbas|Rau, Tilman T|Hartmann, Arndt|Stoehr, Robert | ||||||||||
| PMID: | 24503755 | ||||||||||
| 46. | |||||||||||
| Journal: | Clin Biochem. 2014 Jan;47(1-2):111-6. | ||||||||||
| Title: | Concomitant PIK3CA amplification and RASSF1A or PAX6 hypermethylation predict worse survival in gastric cancer. | ||||||||||
| Author: | Yang, Qi|Shao, Yuan|Shi, Jing|Qu, Yiping|Wu, Kexia|Dang, Siwen|Shi, Bingyin|Hou, Peng | ||||||||||
| PMID: | 24505629 | ||||||||||
| 47. | |||||||||||
| Journal: | Br J Pharmacol. 2014 Jul;171(13):3255-67. | ||||||||||
| Title: | Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype. | ||||||||||
| Author: | Bhattacharya, B|Low, S H H|Soh, C|Kamal Mustapa, N|Beloueche-Babari, M|Koh, K X|Loh, J|Soong, R | ||||||||||
| PMID: | 24597478 | ||||||||||
| 48. | |||||||||||
| Journal: | Arch Iran Med. 2014 Apr;17(4):286-92. | ||||||||||
| Title: | Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions. | ||||||||||
| Author: | Abedi-Ardekani, Behnoush|Hainaut, Pierre | ||||||||||
| PMID: | 24724606 | ||||||||||
| 49. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2014 Aug;140(8):1399-411. | ||||||||||
| Title: | A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer. | ||||||||||
| Author: | Wang, Xiaoting|Lin, Youdong|Lan, Fenghua|Yu, Yinghao|Ouyang, Xuenong|Wang, Xuzhou|Huang, Qiaojia|Wang, Lie|Tan, Jianming|Zheng, Feng | ||||||||||
| PMID: | 24737346 | ||||||||||
| 50. | |||||||||||
| Journal: | BMC Res Notes. 2014 Apr 29;7:271. | ||||||||||
| Title: | Clinicopathological features and prognostic roles of KRAS, BRAF, PIK3CA and NRAS mutations in advanced gastric cancer. | ||||||||||
| Author: | Takahashi, Naoki|Yamada, Yasuhide|Taniguchi, Hirokazu|Fukahori, Masaru|Sasaki, Yusuke|Shoji, Hirokazu|Honma, Yoshitaka|Iwasa, Satoru|Takashima, Atsuo|Kato, Ken|Hamaguchi, Tetsuya|Shimada, Yasuhiro | ||||||||||
| PMID: | 24774510 | ||||||||||
| 51. | |||||||||||
| Journal: | Tumour Biol. 2014 Oct;35(10):9801-6. | ||||||||||
| Title: | MiRNA-34a inhibits EGFR-signaling-dependent MMP7 activation in gastric cancer. | ||||||||||
| Author: | Liu, Gang|Jiang, Chuanshen|Li, Dazhou|Wang, Rong|Wang, Wen | ||||||||||
| PMID: | 24981249 | ||||||||||
| 52. | |||||||||||
| Journal: | J Pathol. 2014 Nov;234(3):365-74. | ||||||||||
| Title: | The mutational burdens and evolutionary ages of early gastric cancers are comparable to those of advanced gastric cancers. | ||||||||||
| Author: | Kim, Tae-Min|Jung, Seung-Hyun|Kim, Min Sung|Baek, In-Pyo|Park, Sung-Won|Lee, Sung Hak|Lee, Han Hong|Kim, Sung Soo|Chung, Yeun-Jun|Lee, Sug Hyung | ||||||||||
| PMID: | 25042771 | ||||||||||
| 53. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2014 Oct;34(10):1503-6. | ||||||||||
| Title: | [Chitosan/PIK3CA siRNA nanoparticle-mediated PIK3CA gene interference decreases the invasive capacity of gastric cancer cells in vitro]. | ||||||||||
| Author: | Zhou, Xinke|He, Lu|Liang, Min|Liu, Jifang | ||||||||||
| PMID: | 25345950 | ||||||||||
| 54. | |||||||||||
| Journal: | PLoS One. 2014 Nov 5;9(11):e111693. | ||||||||||
| Title: | High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer. | ||||||||||
| Author: | Kim, Seokhwi|Lee, Jeeyun|Hong, Min Eui|Do, In-Gu|Kang, So Young|Ha, Sang Yun|Kim, Seung Tae|Park, Se Hoon|Kang, Won Ki|Choi, Min-Gew|Lee, Jun Ho|Sohn, Tae Sung|Bae, Jae Moon|Kim, Sung|Kim, Duk-Hwan|Kim, Kyoung-Mee | ||||||||||
| PMID: | 25372287 | ||||||||||
| 55. | |||||||||||
| Journal: | Mutat Res. 2014 Nov;769:108-12. | ||||||||||
| Title: | Occurrence of low frequency PIK3CA and AKT2 mutations in gastric cancer. | ||||||||||
| Author: | Zhang, Qing-Ying|Cheng, Wen-Xiang|Li, Wen-Mei|Au, William|Lu, You-Yong | ||||||||||
| PMID: | 25771729 | ||||||||||
| 56. | |||||||||||
| Journal: | Gastric Cancer. 2015 Jan;18(1):65-76. | ||||||||||
| Title: | Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer. | ||||||||||
| Author: | Yoda, Yukie|Takeshima, Hideyuki|Niwa, Tohru|Kim, Jeong Goo|Ando, Takayuki|Kushima, Ryoji|Sugiyama, Toshiro|Katai, Hitoshi|Noshiro, Hirokazu|Ushijima, Toshikazu | ||||||||||
| PMID: | 24510342 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncology. 2015;88(2):76-85. | ||||||||||
| Title: | PTEN deficiency as a predictive biomarker of resistance to HER2-targeted therapy in advanced gastric cancer. | ||||||||||
| Author: | Zhang, Xianglan|Park, Ji Soo|Park, Kyu Hyun|Kim, Ki Hyang|Jung, Minkyu|Chung, Hyun Cheol|Rha, Sun Young|Kim, Hyo Song | ||||||||||
| PMID: | 25300346 | ||||||||||
| 58. | |||||||||||
| Journal: | Exp Mol Med. 2015 Jan 23;47:e134. | ||||||||||
| Title: | Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma. | ||||||||||
| Author: | Gulley, Margaret L | ||||||||||
| PMID: | 25613731 | ||||||||||
| 59. | |||||||||||
| Journal: | Int J Oncol. 2015 Apr;46(4):1421-34. | ||||||||||
| Title: | Update on Epstein-Barr virus and gastric cancer (review). | ||||||||||
| Author: | Shinozaki-Ushiku, Aya|Kunita, Akiko|Fukayama, Masashi | ||||||||||
| PMID: | 25633561 | ||||||||||
| 60. | |||||||||||
| Journal: | Cancer Biol Ther. 2015;16(5):764-9. | ||||||||||
| Title: | Tumor profiling of gastric and esophageal carcinoma reveal different treatment options. | ||||||||||
| Author: | Miura, John T|Xiu, Joanne|Thomas, James|George, Ben|Carron, Benjamin R|Tsai, Susan|Johnston, Fabian M|Turaga, Kiran K|Gamblin, T Clark | ||||||||||
| PMID: | 25778705 | ||||||||||
| 61. | |||||||||||
| Journal: | Mol Med Rep. 2015 Jul;12(1):1219-24. | ||||||||||
| Title: | Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer. | ||||||||||
| Author: | Lu, Weipeng|Wei, Hong|Li, Mei|Wang, Hai|Liu, Lina|Zhang, Qiuping|Liu, Lisha|Lu, Shen | ||||||||||
| PMID: | 25815786 | ||||||||||
| 62. | |||||||||||
| Journal: | Oncologist. 2015 May;20(5):499-507. | ||||||||||
| Title: | Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies. | ||||||||||
| Author: | Ali, Siraj M|Sanford, Eric M|Klempner, Samuel J|Rubinson, Douglas A|Wang, Kai|Palma, Norma A|Chmielecki, Juliann|Yelensky, Roman|Palmer, Gary A|Morosini, Deborah|Lipson, Doron|Catenacci, Daniel V|Braiteh, Fadi|Erlich, Rachel|Stephens, Philip J|Ross, Jeffr | ||||||||||
| PMID: | 25882375 | ||||||||||
| 63. | |||||||||||
| Journal: | BMC Cancer. 2015 Mar 13;15:119. | ||||||||||
| Title: | Successful control of heavily pretreated metastatic gastric cancer with the mTOR inhibitor everolimus (RAD001) in a patient with PIK3CA mutation and pS6 overexpression. | ||||||||||
| Author: | Park, Ji Hyun|Ryu, Min-Hee|Park, Young Soo|Park, Sook Ryun|Na, Young-Soon|Rhoo, Baek-Yeol|Kang, Yoon-Koo | ||||||||||
| PMID: | 25886409 | ||||||||||
| 64. | |||||||||||
| Journal: | Int J Surg Pathol. 2015 Oct;23(7):537-41. | ||||||||||
| Title: | alpha-Fetoprotein-Producing Hepatoid Gastric Adenocarcinoma With Osteoclast-Like Giant Cells and Neuroendocrine Differentiation: A Case Study With Molecular Profiling. | ||||||||||
| Author: | Wincewicz, Andrzej|Kowalik, Artur|Zieba, Sebastian|Lewitowicz, Piotr|Gozdz, Stanislaw|Sulkowski, Stanislaw | ||||||||||
| PMID: | 26009570 | ||||||||||
| 65. | |||||||||||
| Journal: | Drug Des Devel Ther. 2015 Jul 16;9:3607-16. | ||||||||||
| Title: | Downregulation of miR203 induces overexpression of PIK3CA and predicts poor prognosis of gastric cancer patients. | ||||||||||
| Author: | Liang, Min|Shi, Boyun|Liu, Jifang|He, Lu|Yi, Gao|Zhou, Lin|Yu, Guifang|Zhou, Xinke | ||||||||||
| PMID: | 26213461 | ||||||||||
| 66. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 29;6(29):26935-45. | ||||||||||
| Title: | Deregulation of ARID1A, CDH1, cMET and PIK3CA and target-related microRNA expression in gastric cancer. | ||||||||||
| Author: | Ibarrola-Villava, Maider|Llorca-Cardenosa, Marta J|Tarazona, Noelia|Mongort, Cristina|Fleitas, Tania|Perez-Fidalgo, Jose Alejandro|Rosello, Susana|Navarro, Samuel|Ribas, Gloria|Cervantes, Andres | ||||||||||
| PMID: | 26334097 | ||||||||||
| 67. | |||||||||||
| Journal: | Pathobiology. 2015;82(5):212-23. | ||||||||||
| Title: | Epstein-Barr Virus-Associated Gastric Carcinoma: Use of Host Cell Machineries and Somatic Gene Mutations. | ||||||||||
| Author: | Abe, Hiroyuki|Kaneda, Atsushi|Fukayama, Masashi | ||||||||||
| PMID: | 26337667 | ||||||||||
| 68. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12492-7. | ||||||||||
| Title: | Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. | ||||||||||
| Author: | Park, Hansoo|Cho, Sung-Yup|Kim, Hyerim|Na, Deukchae|Han, Jee Yun|Chae, Jeesoo|Park, Changho|Park, Ok-Kyoung|Min, Seoyeon|Kang, Jinjoo|Choi, Boram|Min, Jimin|Kwon, Jee Young|Suh, Yun-Suhk|Kong, Seong-Ho|Lee, Hyuk-Joon|Liu, Edison T|Kim, Jong-Il|Kim, Sungho | ||||||||||
| PMID: | 26401016 | ||||||||||
| 69. | |||||||||||
| Journal: | Drug Des Devel Ther. 2015 Oct 19;9:5697-704. | ||||||||||
| Title: | Overexpression of PI3K p110alpha contributes to acquired resistance to MET inhibitor, in MET-amplified SNU-5 gastric xenografts. | ||||||||||
| Author: | Ji, Fujian|Liu, Xuanwen|Wu, Yuanyu|Fang, Xuedong|Huang, Guomin | ||||||||||
| PMID: | 26543351 | ||||||||||
| 70. | |||||||||||
| Journal: | World J Gastroenterol. 2015 Nov 21;21(43):12261-73. | ||||||||||
| Title: | Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? | ||||||||||
| Author: | Singh, Shikha Satendra|Yap, Wei Ney|Arfuso, Frank|Kar, Shreya|Wang, Chao|Cai, Wanpei|Dharmarajan, Arunasalam M|Sethi, Gautam|Kumar, Alan Prem | ||||||||||
| PMID: | 26604635 | ||||||||||
| 71. | |||||||||||
| Journal: | Histopathology. 2016 Jan;68(2):241-53. | ||||||||||
| Title: | MET in gastric cancer--discarding a 10% cutoff rule. | ||||||||||
| Author: | Metzger, Marie-Luise|Behrens, Hans-Michael|Boger, Christine|Haag, Jochen|Kruger, Sandra|Rocken, Christoph | ||||||||||
| PMID: | 26033401 | ||||||||||
| 72. | |||||||||||
| Journal: | J Clin Pathol. 2016 Jan;69(1):70-5. | ||||||||||
| Title: | Clinicopathological characteristics of RHOA mutations in a Central European gastric cancer cohort. | ||||||||||
| Author: | Rocken, Christoph|Behrens, Hans-Michael|Boger, Christine|Kruger, Sandra | ||||||||||
| PMID: | 26251521 | ||||||||||
| 73. | |||||||||||
| Journal: | Ann Oncol. 2016 Jan;27(1):127-33. | ||||||||||
| Title: | Comprehensive analyses using next-generation sequencing and immunohistochemistry enable precise treatment in advanced gastric cancer. | ||||||||||
| Author: | Kuboki, Y|Yamashita, S|Niwa, T|Ushijima, T|Nagatsuma, A|Kuwata, T|Yoshino, T|Doi, T|Ochiai, A|Ohtsu, A | ||||||||||
| PMID: | 26489445 | ||||||||||
| 74. | |||||||||||
| Journal: | Oncotarget. 2016 Feb 2;7(5):6201-20. | ||||||||||
| Title: | Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers. | ||||||||||
| Author: | Fang, Wen-Liang|Huang, Kuo-Hung|Lan, Yuan-Tzu|Lin, Chien-Hsing|Chang, Shih-Ching|Chen, Ming-Huang|Chao, Yee|Lin, Wen-Chang|Lo, Su-Shun|Li, Anna Fen-Yau|Wu, Chew-Wun|Chiou, Shih-Hwa|Shyr, Yi-Ming | ||||||||||
| PMID: | 26701847 | ||||||||||
| 75. | |||||||||||
| Journal: | Oncotarget. 2016 Feb 16;7(7):8055-66. | ||||||||||
| Title: | Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites. | ||||||||||
| Author: | Lim, Byungho|Kim, Chan|Kim, Jeong-Hwan|Kwon, Woo Sun|Lee, Won Seok|Kim, Jeong Min|Park, Jun Yong|Kim, Hyo Song|Park, Kyu Hyun|Kim, Tae Soo|Park, Jong-Lyul|Chung, Hyun Cheol|Rha, Sun Young|Kim, Seon-Young | ||||||||||
| PMID: | 26811494 | ||||||||||
| 76. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 1;7(9):10547-56. | ||||||||||
| Title: | Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus. | ||||||||||
| Author: | Lim, Sun Min|Park, Hyung Soon|Kim, Sangwoo|Kim, Sora|Ali, Siraj M|Greenbowe, Joel R|Yang, In Seok|Kwon, Nak-Jung|Lee, Jae Lyun|Ryu, Min-Hee|Ahn, Jin-Hee|Lee, Jeeyun|Lee, Min Goo|Kim, Hyo Song|Kim, Hyunki|Kim, Hye Ryun|Moon, Yong Wha|Chung, Hyun Cheol|Kim, | ||||||||||
| PMID: | 26859683 | ||||||||||
| 77. | |||||||||||
| Journal: | BMC Cancer. 2016 Mar 9;16:200. | ||||||||||
| Title: | Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems. | ||||||||||
| Author: | Chang, Hae Ryung|Park, Hee Seo|Ahn, Young Zoo|Nam, Seungyoon|Jung, Hae Rim|Park, Sungjin|Lee, Sang Jin|Balch, Curt|Powis, Garth|Ku, Ja-Lok|Kim, Yon Hui | ||||||||||
| PMID: | 26955870 | ||||||||||
| 78. | |||||||||||
| Journal: | Sci Rep. 2016 Mar 10;6:22982. | ||||||||||
| Title: | Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis. | ||||||||||
| Author: | Bria, E|Pilotto, S|Simbolo, M|Fassan, M|de Manzoni, G|Carbognin, L|Sperduti, I|Brunelli, M|Cataldo, I|Tomezzoli, A|Mafficini, A|Turri, G|Karachaliou, N|Rosell, R|Tortora, G|Scarpa, A | ||||||||||
| PMID: | 26961069 | ||||||||||
| 79. | |||||||||||
| Journal: | Hum Pathol. 2016 Jul;53:25-34. | ||||||||||
| Title: | Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus-associated gastric carcinoma. | ||||||||||
| Author: | Dong, Min|Wang, Hai-Yan|Zhao, Xiao-Xiao|Chen, Jian-Ning|Zhang, Yi-Wang|Huang, Yan|Xue, Ling|Li, Hai-Gang|Du, Hong|Wu, Xiang-Yuan|Shao, Chun-Kui | ||||||||||
| PMID: | 26980034 | ||||||||||
| 80. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 26;7(17):24269-83. | ||||||||||
| Title: | PD-L1 is an independent prognostic predictor in gastric cancer of Western patients. | ||||||||||
| Author: | Boger, Christine|Behrens, Hans-Michael|Mathiak, Micaela|Kruger, Sandra|Kalthoff, Holger|Rocken, Christoph | ||||||||||
| PMID: | 27009855 | ||||||||||
| 81. | |||||||||||
| Journal: | Pathol Oncol Res. 2016 Oct;22(4):797-805. | ||||||||||
| Title: | The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines. | ||||||||||
| Author: | Riquelme, Ismael|Tapia, Oscar|Espinoza, Jaime A|Leal, Pamela|Buchegger, Kurt|Sandoval, Alejandra|Bizama, Carolina|Araya, Juan Carlos|Peek, Richard M|Roa, Juan Carlos | ||||||||||
| PMID: | 27156070 | ||||||||||
| 82. | |||||||||||
| Journal: | Front Physiol. 2016 May 9;7:168. | ||||||||||
| Title: | The Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal Cancer. | ||||||||||
| Author: | Kim, Hong Jun|Lee, Suk-Young|Oh, Sang Cheul | ||||||||||
| PMID: | 27242542 | ||||||||||
| 83. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 19;7(29):46127-46141. | ||||||||||
| Title: | |||||||||||