Primary Site >> Colorectal Cancer

Gene >> PHLPP2

Journal: J Biol Chem. 2008 Mar 7;283(10):6300-11. Epub 2007 Dec 27.
Title: The phosphatase PHLPP controls the cellular levels of protein kinase C.
Author: Gao, Tianyan|Brognard, John|Newton, Alexandra C
PMID: 18162466
Journal: Oncogene. 2009 Feb 19;28(7):994-1004.
Title: Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis.
Author: Liu, J|Weiss, H L|Rychahou, P|Jackson, L N|Evers, B M|Gao, T
PMID: 19079341
Journal: J Biol Chem. 2011 Feb 25;286(8):6510-20.
Title: mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
Author: Liu, Jianyu|Stevens, Payton D|Gao, Tianyan
PMID: 21177869
Journal: Cancer Res. 2013 May 1;73(9):2806-16.
Title: Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice.
Author: Xu, Changxin|Reichert, Ethan C|Nakano, Tomoyuki|Lohse, Mariah|Gardner, Alison A|Revelo, Monica P|Topham, Matthew K|Stafforini, Diana M
PMID: 23361301
Journal: Clin Cancer Res. 2013 Sep 1;19(17):4662-72.
Title: microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.
Author: Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing
PMID: 23846336
Journal: Gastroenterology. 2014 May;146(5):1301-12.e1-10.
Title: PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Author: Li, Xin|Stevens, Payton D|Liu, Jianyu|Yang, Haihua|Wang, Wei|Wang, Chi|Zeng, Zheng|Schmidt, Micheal D|Yang, Mike|Lee, Eun Y|Gao, Tianyan
PMID: 24530606
Journal: Oncotarget. 2014 Feb 15;5(3):815-23.
Title: PHLPP2 suppresses the NF-kappaB pathway by inactivating IKKbeta kinase.
Author: Agarwal, Nitin Kumar|Zhu, Xiaoping|Gagea, Mihai|White, Charles L 3rd|Cote, Gilbert|Georgescu, Maria-Magdalena
PMID: 24553260
Journal: Eur J Pharmacol. 2017 Jul 15;807:168-173.
Title: miR-938 promotes colorectal cancer cell proliferation via targeting tumor suppressor PHLPP2.
Author: Li, Chang-Feng|Li, Yong-Chao|Jin, Jing-Peng|Yan, Zhen-Kun|Li, Dan-Dan
PMID: 28433657
Journal: Biomed Res Int. 2017;2017:2421459.
Title: Prediction and Validation of Hub Genes Associated with Colorectal Cancer by Integrating PPI Network and Gene Expression Data.
Author: Xiong, Yongfu|You, Wenxian|Wang, Rong|Peng, Linglong|Fu, Zhongxue
PMID: 29209625
Journal: Cancer Lett. 2018 Sep 1;431:213-218.
Title: Human colorectal cancer initiation is bidirectional, and cell growth, metabolic genes and transporter genes are early drivers of tumorigenesis.
Author: Hong, Yi|Liew, Soo Chin|Thean, Lai Fun|Tang, Choong Leong|Cheah, Peh Yean
PMID: 29885515