Primary Site >> Colorectal Cancer
Gene >> PHLPP1
| 1. | |||||||||||
| Journal: | Mol Cell. 2005 Apr 1;18(1):13-24. | ||||||||||
| Title: | PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. | ||||||||||
| Author: | Gao, Tianyan|Furnari, Frank|Newton, Alexandra C | ||||||||||
| PMID: | 15808505 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2008 Mar 7;283(10):6300-11. Epub 2007 Dec 27. | ||||||||||
| Title: | The phosphatase PHLPP controls the cellular levels of protein kinase C. | ||||||||||
| Author: | Gao, Tianyan|Brognard, John|Newton, Alexandra C | ||||||||||
| PMID: | 18162466 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2009 Feb 19;28(7):994-1004. | ||||||||||
| Title: | Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. | ||||||||||
| Author: | Liu, J|Weiss, H L|Rychahou, P|Jackson, L N|Evers, B M|Gao, T | ||||||||||
| PMID: | 19079341 | ||||||||||
| 4. | |||||||||||
| Journal: | Anticancer Res. 2009 Aug;29(8):3185-90. | ||||||||||
| Title: | Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. | ||||||||||
| Author: | Johnson, Sara M|Gulhati, Pat|Arrieta, Isela|Wang, Xiaofu|Uchida, Tatsuo|Gao, Tianyan|Evers, B Mark | ||||||||||
| PMID: | 19661333 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cell Biol. 2009 Dec;29(23):6192-205. | ||||||||||
| Title: | beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt. | ||||||||||
| Author: | Li, Xin|Liu, Jianyu|Gao, Tianyan | ||||||||||
| PMID: | 19797085 | ||||||||||
| 6. | |||||||||||
| Journal: | J Biol Chem. 2011 Feb 25;286(8):6510-20. | ||||||||||
| Title: | mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells. | ||||||||||
| Author: | Liu, Jianyu|Stevens, Payton D|Gao, Tianyan | ||||||||||
| PMID: | 21177869 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2013 Jan 24;32(4):471-8. | ||||||||||
| Title: | The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer. | ||||||||||
| Author: | Li, X|Stevens, P D|Yang, H|Gulhati, P|Wang, W|Evers, B M|Gao, T | ||||||||||
| PMID: | 22391563 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Sep 1;19(17):4662-72. | ||||||||||
| Title: | microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2. | ||||||||||
| Author: | Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing | ||||||||||
| PMID: | 23846336 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cell Biol. 2013 Nov;33(22):4594-605. | ||||||||||
| Title: | Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells. | ||||||||||
| Author: | Wen, Yang-An|Stevens, Payton D|Gasser, Michael L|Andrei, Romina|Gao, Tianyan | ||||||||||
| PMID: | 24061475 | ||||||||||
| 10. | |||||||||||
| Journal: | J Biol Chem. 2013 Nov 29;288(48):34545-54. | ||||||||||
| Title: | WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1). | ||||||||||
| Author: | Gangula, Narmadha Reddy|Maddika, Subbareddy | ||||||||||
| PMID: | 24145035 | ||||||||||
| 11. | |||||||||||
| Journal: | Gastroenterology. 2014 May;146(5):1301-12.e1-10. | ||||||||||
| Title: | PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice. | ||||||||||
| Author: | Li, Xin|Stevens, Payton D|Liu, Jianyu|Yang, Haihua|Wang, Wei|Wang, Chi|Zeng, Zheng|Schmidt, Micheal D|Yang, Mike|Lee, Eun Y|Gao, Tianyan | ||||||||||
| PMID: | 24530606 | ||||||||||
| 12. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2015;19(8):1017-26. | ||||||||||
| Title: | MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1. | ||||||||||
| Author: | Mussnich, Paula|Rosa, Roberta|Bianco, Roberto|Fusco, Alfredo|D'Angelo, Daniela | ||||||||||
| PMID: | 26107137 | ||||||||||
| 13. | |||||||||||
| Journal: | Elife. 2015 Nov 27;4. | ||||||||||
| Title: | Greatwall promotes cell transformation by hyperactivating AKT in human malignancies. | ||||||||||
| Author: | Vera, Jorge|Lartigue, Lydia|Vigneron, Suzanne|Gadea, Gilles|Gire, Veronique|Del Rio, Maguy|Soubeyran, Isabelle|Chibon, Frederic|Lorca, Thierry|Castro, Anna | ||||||||||
| PMID: | 26613407 | ||||||||||
| 14. | |||||||||||
| Journal: | Cell Death Discov. 2017 Jan 23;3:16103. | ||||||||||
| Title: | PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells. | ||||||||||
| Author: | Xiong, Xiaopeng|Wen, Yang-An|Mitov, Mihail I|C Oaks, Mary|Miyamoto, Shigeki|Gao, Tianyan | ||||||||||
| PMID: | 28179998 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer. 2018 Mar 1;124(5):1070-1082. | ||||||||||
| Title: | A mutational comparison of adult and adolescent and young adult (AYA) colon cancer. | ||||||||||
| Author: | Tricoli, James V|Boardman, Lisa A|Patidar, Rajesh|Sindiri, Sivasish|Jang, Jin S|Walsh, William D|McGregor, Paul M 3rd|Camalier, Corinne E|Mehaffey, Michele G|Furman, Wayne L|Bahrami, Armita|Williams, P Mickey|Lih, Chih-Jian|Conley, Barbara A|Khan, Javed | ||||||||||
| PMID: | 29194591 | ||||||||||