Primary Site >> Colorectal Cancer

Gene >> PGP

Journal: Biochemistry. 1990 Nov 13;29(45):10351-6.
Title: Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.
Author: Murphy, L D|Herzog, C E|Rudick, J B|Fojo, A T|Bates, S E
PMID: 1979752
Journal: J Natl Cancer Inst. 1992 May 6;84(9):711-6.
Title: Various methods of analysis of mdr-1/P-glycoprotein in human colon cancer cell lines.
Author: Herzog, C E|Trepel, J B|Mickley, L A|Bates, S E|Fojo, A T
PMID: 1349044
Journal: Int J Cancer. 1993 May 8;54(2):275-81.
Title: Modulation of mdr-1 expression by a H-ras oncogene in a human colon carcinoma cell line.
Author: Kramer, R|Weber, T K|Arceci, R|Morse, B|Simpson, H|Steele, G D Jr|Summerhayes, I C
PMID: 8098015
Journal: Br J Cancer. 1993 May;67(5):959-68.
Title: Constitutive expression of multidrug resistance in human colorectal tumours and cell lines.
Author: Kramer, R|Weber, T K|Morse, B|Arceci, R|Staniunas, R|Steele, G Jr|Summerhayes, I C
PMID: 8098614
Journal: J Cancer Res Clin Oncol. 1993;119(10):609-14.
Title: In vitro and in vivo chemosensitizing effect of cyclosporin A on an intrinsic multidrug-resistant rat colon tumour.
Author: Van de Vrie, W|Gheuens, E E|Durante, N M|De Bruijn, E A|Marquet, R L|Van Oosterom, A T|Eggermont, A M
PMID: 8101524
Journal: J Clin Oncol. 1994 Apr;12(4):812-9.
Title: Clinical and pharmacologic study of multidrug resistance reversal with vinblastine and bepridil.
Author: Linn, S C|van Kalken, C K|van Tellingen, O|van der Valk, P|van Groeningen, C J|Kuiper, C M|Pinedo, H M|Giaccone, G
PMID: 7908691
Journal: Br J Cancer. 1995 Nov;72(5):1083-8.
Title: Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs.
Author: Blakey, D C|Davies, D H|Dowell, R I|East, S J|Burke, P J|Sharma, S K|Springer, C J|Mauger, A B|Melton, R G
PMID: 7577451
Journal: FEBS Lett. 1995 Jul 17;368(2):373-6.
Title: Cell-specific effects of RAS oncogene and protein kinase C agonist TPA on P-glycoprotein function.
Author: Stromskaya, T P|Grigorian, I A|Ossovskaya, V S|Rybalkina, E Y|Chumakov, P M|Kopnin, B P
PMID: 7628641
Journal: Eur J Cancer. 1995 Dec;31A(13-14):2313-9.
Title: The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts.
Author: Jansen, W J|Pinedo, H M|van der Wilt, C L|Feller, N|Bamberger, U|Boven, E
PMID: 8652262
Journal: Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4001-5.
Title: P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
Author: Schuetz, E G|Schinkel, A H|Relling, M V|Schuetz, J D
PMID: 8633005
Journal: Anticancer Drugs. 1996 Nov;7(8):838-45.
Title: Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta.
Author: Bertram, J|Palfner, K|Hiddemann, W|Kneba, M
PMID: 8991187
Journal: Int J Oncol. 1996 Jun;8(6):1095-104.
Title: Anti-tumor ribonuclease, combined with or conjugated to monoclonal antibody MRK16, overcomes multidrug resistance to vincristine in vitro and in vivo.
Author: Newton, D|Pearson, J|Xue, Y|Smith, M|Fogler, W|Mikulski, S|Alvord, W|Kung, H|Long, D|Rybak, S
PMID: 21544469
Journal: J Biol Chem. 1997 Apr 25;272(17):11518-25.
Title: Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway.
Author: Furuya, K N|Thottassery, J V|Schuetz, E G|Sharif, M|Schuetz, J D
PMID: 9111066
Journal: Cancer Res. 1998 Dec 15;58(24):5850-8.
Title: Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.
Author: Rabindran, S K|He, H|Singh, M|Brown, E|Collins, K I|Annable, T|Greenberger, L M
PMID: 9865745
Journal: Eur J Cancer. 1999 Jun;35(6):935-8.
Title: Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer.
Author: Fukushima, Y|Oshika, Y|Tokunaga, T|Hatanaka, H|Tomisawa, M|Kawai, K|Ozeki, Y|Tsuchida, T|Kijima, H|Yamazaki, H|Ueyama, Y|Tamaoki, N|Miura, S|Nakamura, M
PMID: 10533474
Journal: Int J Cancer. 2000 Oct 15;88(2):260-6.
Title: New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer.
Author: Van Hattum, A H|Pinedo, H M|Schluper, H M|Hausheer, F H|Boven, E
PMID: 11004678
Journal: Rev Physiol Biochem Pharmacol. 2001;142:1-96.
Title: Modulation of protein kinase C in antitumor treatment.
Author: Hofmann, J
PMID: 11190577
Journal: Cancer Lett. 2001 Apr 10;165(1):111-6.
Title: Differential anthracycline sensitivity in two related human colon carcinoma cell lines expressing similar levels of P-glycoprotein.
Author: Boquete, A L|Vargas Roig, L|Lopez, G A|Gude, R|Binda, M M|Gonzalez, A D|Ciocca, D R|Bonfil, R D
PMID: 11248426
Journal: Drug Metab Dispos. 2002 Jul;30(7):763-70.
Title: Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1.
Author: Luo, Feng R|Paranjpe, Pankaj V|Guo, Ailan|Rubin, Eric|Sinko, Patrick
PMID: 12065434
Journal: Biochem Pharmacol. 2002 Oct 15;64(8):1267-77.
Title: The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer.
Author: van Hattum, Annemarie H|Pinedo, Herbert M|Schluper, Hennie M M|Erkelens, Caroline A M|Tohgo, Akiko|Boven, Epie
PMID: 12234607
Journal: Acta Oncol. 2002;41(6):543-9.
Title: Changes in the colonic enteric nervous system in rats with chemically induced colon dysplasia and carcinoma.
Author: Sitohy, Basel|El-Salhy, Magdy
PMID: 12546527
Journal: Cytometry A. 2004 Oct;61(2):105-16.
Title: Raft and cytoskeleton associations of an ABC transporter: P-glycoprotein.
Author: Bacso, Zsolt|Nagy, Henrietta|Goda, Katalin|Bene, Laszlo|Fenyvesi, Ferenc|Matko, Janos|Szabo, Gabor
PMID: 15382145
Journal: Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title: Molecular markers that predict response to colon cancer therapy.
Author: Ahmed, Farid E
PMID: 15934813
Journal: J Gastroenterol Hepatol. 2005 Aug;20(8):1292-8.
Title: Decreased density of interstitial cells of Cajal and neuronal cells in patients with slow-transit constipation and acquired megacolon.
Author: Lee, Jung Il|Park, Hyojin|Kamm, Michael A|Talbot, Ian C
PMID: 16048580
Journal: Med Chem. 2005 Mar;1(2):125-39.
Title: Recent advances in the new generation taxane anticancer agents.
Author: Geney, R|Chen, J|Ojima, I
PMID: 16787308
Journal: PLoS One. 2009 Oct 2;4(10):e7238.
Title: Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters.
Author: Fayad, Walid|Fryknas, Marten|Brnjic, Slavica|Olofsson, Maria Hagg|Larsson, Rolf|Linder, Stig
PMID: 19798419
Journal: Mol Pharm. 2015 Jun 1;12(6):1752-61.
Title: Sensitive ELISA Method for the Measurement of Catabolites of Antibody-Drug Conjugates (ADCs) in Target Cancer Cells.
Author: Salomon, Paulin L|Singh, Rajeeva
PMID: 25738394
Journal: Mol Med Rep. 2016 Mar;13(3):2583-9.
Title: The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells.
Author: Yang, Guanglei|Xu, Shuqing|Peng, Lintao|Li, Hui|Zhao, Yan|Hu, Yanfang
PMID: 26846577
Journal: J Pharm Sci. 2017 Sep;106(9):2632-2641.
Title: Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites.
Author: Fujita, Ken-Ichi|Masuo, Yusuke|Yamazaki, Erina|Shibutani, Toshiki|Kubota, Yutaro|Nakamichi, Noritaka|Sasaki, Yasutsuna|Kato, Yukio
PMID: 28479358
Journal: Mol Cell Biochem. 2018 Apr 11. pii: 10.1007/s11010-018-3346-4.
Title: Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells.
Author: Iyer, Vidhya V|Priya, P Yoga|Kangeyavelu, Jeipreeti
PMID: 29644529
Journal: Oncotarget. 2018 Apr 20;9(30):21211-21223.
Title: Chemopreventive activity of celastrol in drug-resistant human colon carcinoma cell cultures.
Author: Moreira, Helena|Szyjka, Anna|Gasiorowski, Kazimierz
PMID: 29765532