Primary Site >> Colorectal Cancer
Gene >> PGP
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Ref: Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression. PMID: 1979752 |
Ref: Various methods of analysis of mdr-1/P-glycoprotein in human colon cancer cell lines. PMID: 1349044 |
Ref: Modulation of mdr-1 expression by a H-ras oncogene in a human colon carcinoma cell line. PMID: 8098015 Ref: Constitutive expression of multidrug resistance in human colorectal tumours and cell lines. PMID: 8098614 Ref: In vitro and in vivo chemosensitizing effect of cyclosporin A on an intrinsic multidrug-resistant rat colon tumour. PMID: 8101524 |
Ref: Clinical and pharmacologic study of multidrug resistance reversal with vinblastine and bepridil. PMID: 7908691 |
Ref: Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs. PMID: 7577451 Ref: Cell-specific effects of RAS oncogene and protein kinase C agonist TPA on P-glycoprotein function. PMID: 7628641 Ref: The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts. PMID: 8652262 |
Ref: P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans. PMID: 8633005 Ref: Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta. PMID: 8991187 Ref: Anti-tumor ribonuclease, combined with or conjugated to monoclonal antibody MRK16, overcomes multidrug resistance to vincristine in vitro and in vivo. PMID: 21544469 |
Ref: Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway. PMID: 9111066 |
Ref: Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. PMID: 9865745 |
Ref: Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer. PMID: 10533474 |
Ref: New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer. PMID: 11004678 |
Ref: Modulation of protein kinase C in antitumor treatment. PMID: 11190577 Ref: Differential anthracycline sensitivity in two related human colon carcinoma cell lines expressing similar levels of P-glycoprotein. PMID: 11248426 |
Ref: Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1. PMID: 12065434 Ref: The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer. PMID: 12234607 Ref: Changes in the colonic enteric nervous system in rats with chemically induced colon dysplasia and carcinoma. PMID: 12546527 |
Ref: Raft and cytoskeleton associations of an ABC transporter: P-glycoprotein. PMID: 15382145 |
Ref: Molecular markers that predict response to colon cancer therapy. PMID: 15934813 Ref: Decreased density of interstitial cells of Cajal and neuronal cells in patients with slow-transit constipation and acquired megacolon. PMID: 16048580 Ref: Recent advances in the new generation taxane anticancer agents. PMID: 16787308 |
Ref: Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters. PMID: 19798419 |
Ref: Sensitive ELISA Method for the Measurement of Catabolites of Antibody-Drug Conjugates (ADCs) in Target Cancer Cells. PMID: 25738394 |
Ref: The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells. PMID: 26846577 |
Ref: Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites. PMID: 28479358 |
Ref: Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells. PMID: 29644529 Ref: Chemopreventive activity of celastrol in drug-resistant human colon carcinoma cell cultures. PMID: 29765532 |