Primary Site >> Stomach Cancer

Gene >> PDK1

Journal: Endocr Relat Cancer. 2009 Jun;16(2):599-611.
Title: Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
Author: Alvarez, Carlos J P|Lodeiro, Maria|Theodoropoulou, Marily|Camina, Jesus P|Casanueva, Felipe F|Pazos, Yolanda
PMID: 19153210
Journal: Cancer Res. 2010 Mar 15;70(6):2339-49.
Title: MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta.
Author: Tsukamoto, Yoshiyuki|Nakada, Chisato|Noguchi, Tsuyoshi|Tanigawa, Masato|Nguyen, Lam Tung|Uchida, Tomohisa|Hijiya, Naoki|Matsuura, Keiko|Fujioka, Toshio|Seto, Masao|Moriyama, Masatsugu
PMID: 20215506
Journal: PPAR Res. 2010;2010:571783.
Title: Induction of metastatic gastric cancer by peroxisome proliferator-activated receptordelta activation.
Author: Pollock, Claire B|Rodriguez, Olga|Martin, Philip L|Albanese, Chris|Li, Xin|Kopelovich, Levy|Glazer, Robert I
PMID: 21318167
Journal: Expert Opin Ther Targets. 2011 Aug;15(8):961-72.
Title: Targeting miR-375 in gastric cancer.
Author: Xu, Yanjun|Deng, Yujie|Yan, Xiaoyi|Zhou, Tianhua
PMID: 21557705
Journal: Histol Histopathol. 2013 Dec;28(12):1629-38.
Title: Upregulation of GPR34 expression affects the progression and prognosis of human gastric adenocarcinoma by PI3K/PDK1/AKT pathway.
Author: Yu, Weidong|Ma, Shuyun|Wang, Lihong|Zuo, Bo|Li, Mei|Qiao, Zhengguo|Pan, Xiuying|Liu, Yulan|Wang, Jingtong
PMID: 23836308
Journal: Mitochondrion. 2013 Nov;13(6):615-29.
Title: Enzymes involved in l-lactate metabolism in humans.
Author: Adeva, M|Gonzalez-Lucan, M|Seco, M|Donapetry, C
PMID: 24029012
Journal: Exp Cell Res. 2014 Feb 15;321(2):219-30.
Title: Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism.
Author: Xuan, Yi|Hur, Hoon|Ham, In-Hye|Yun, Jisoo|Lee, Ji-Yoon|Shim, Wooyoung|Kim, Young Bae|Lee, Gwang|Han, Sang-Uk|Cho, Yong Kwan
PMID: 24342832
Journal: Oncol Rep. 2015 Jan;33(1):457-63.
Title: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway.
Author: Chen, Fenglin|Zhuang, Mingkai|Zhong, Canmei|Peng, Jun|Wang, Xiaozhong|Li, Jianying|Chen, Zhixin|Huang, Yuehong
PMID: 25333894
Journal: Chin Med J (Engl). 2015 Feb 20;128(4):545-9.
Title: G-protein coupled receptor 34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro.
Author: Jin, Zhong-Tian|Li, Kun|Li, Mei|Ren, Zhi-Gang|Wang, Fu-Shun|Zhu, Ji-Ye|Leng, Xi-Sheng|Yu, Wei-Dong
PMID: 25673461
Journal: Oncotarget. 2016 Mar 1;7(9):9788-800.
Title: Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFkappaB pathway in gastric cancer development.
Author: Zhang, Bao-gui|Hu, Lei|Zang, Ming-de|Wang, He-xiao|Zhao, Wei|Li, Jian-fang|Su, Li-ping|Shao, Zhifeng|Zhao, Xiaodong|Zhu, Zheng-gang|Yan, Min|Liu, Bingya
PMID: 26848521
Journal: Oncotarget. 2016 Mar 22;7(12):15150-60.
Title: An increase in galectin-3 causes cellular unresponsiveness to IFN-gamma-induced signal transduction and growth inhibition in gastric cancer cells.
Author: Tseng, Po-Chun|Chen, Chia-Ling|Shan, Yan-Shen|Lin, Chiou-Feng
PMID: 26934444
Journal: J Biosci. 2016 Mar;41(1):77-85.
Title: MiR-128b is down-regulated in gastric cancer and negatively regulates tumour cell viability by targeting PDK1/Akt/NF-kappaB axis.
Author: Zhang, Ling|Lei, Jun|Fang, Zi-Ling|Xiong, Jian-Ping
PMID: 26949090
Journal: Oncotarget. 2016 Jul 19;7(29):46127-46141.
Title: Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.
Author: Zhang, Qian|Yan, Hai-Bo|Wang, Jie|Cui, Shu-Jian|Wang, Xiao-Qing|Jiang, Ying-Hua|Feng, Li|Yang, Peng-Yuan|Liu, Feng
PMID: 27323812
Journal: Oncogenesis. 2017 Apr 24;6(4):e323.
Title: TCRP1 promotes NIH/3T3 cell transformation by over-activating PDK1 and AKT1.
Author: Wang, C|Liu, H|Qiu, Q|Zhang, Z|Gu, Y|He, Z
PMID: 28436990
Journal: Onco Targets Ther. 2017 Jul 10;10:3353-3362.
Title: The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer.
Author: Chen, Zhaoliang|Liu, Hong|Yang, Huili|Gao, Yukai|Zhang, Gongwen|Hu, Jiaojiao
PMID: 28744139