Primary Site >> Stomach Cancer

Gene >> PDK1

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Ref: Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
PMID: 19153210
 Ref: MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta.
PMID: 20215506
Ref: Induction of metastatic gastric cancer by peroxisome proliferator-activated receptordelta activation.
PMID: 21318167
 Ref: Targeting miR-375 in gastric cancer.
PMID: 21557705
 Ref: Upregulation of GPR34 expression affects the progression and prognosis of human gastric adenocarcinoma by PI3K/PDK1/AKT pathway.
PMID: 23836308
Ref: Enzymes involved in l-lactate metabolism in humans.
PMID: 24029012
 Ref: Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism.
PMID: 24342832
 Ref: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway.
PMID: 25333894
Ref: G-protein coupled receptor 34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro.
PMID: 25673461
 Ref: Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFkappaB pathway in gastric cancer development.
PMID: 26848521
Ref: An increase in galectin-3 causes cellular unresponsiveness to IFN-gamma-induced signal transduction and growth inhibition in gastric cancer cells.
PMID: 26934444
Ref: MiR-128b is down-regulated in gastric cancer and negatively regulates tumour cell viability by targeting PDK1/Akt/NF-kappaB axis.
PMID: 26949090
Ref: Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.
PMID: 27323812
 Ref: TCRP1 promotes NIH/3T3 cell transformation by over-activating PDK1 and AKT1.
PMID: 28436990
Ref: The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer.
PMID: 28744139