Primary Site >> Colorectal Cancer
Gene >> PDE4A
| 1. | |||||||||||
| Journal: | Cancer Res. 2001 May 15;61(10):3961-8. | ||||||||||
| Title: | Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. | ||||||||||
| Author: | Piazza, G A|Thompson, W J|Pamukcu, R|Alila, H W|Whitehead, C M|Liu, L|Fetter, J R|Gresh, W E Jr|Klein-Szanto, A J|Farnell, D R|Eto, I|Grubbs, C J | ||||||||||
| PMID: | 11358813 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2007 Jun 1;67(11):5248-57. | ||||||||||
| Title: | Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase. | ||||||||||
| Author: | McEwan, David G|Brunton, Valerie G|Baillie, George S|Leslie, Nicholas R|Houslay, Miles D|Frame, Margaret C | ||||||||||
| PMID: | 17545604 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Cancer. 2012 Jul 25;11:46. | ||||||||||
| Title: | Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model. | ||||||||||
| Author: | Tsunoda, Toshiyuki|Ota, Takeharu|Fujimoto, Takahiro|Doi, Keiko|Tanaka, Yoko|Yoshida, Yasuhiro|Ogawa, Masahiro|Matsuzaki, Hiroshi|Hamabashiri, Masato|Tyson, Darren R|Kuroki, Masahide|Miyamoto, Shingo|Shirasawa, Senji | ||||||||||
| PMID: | 22830422 | ||||||||||
| 4. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2013 Dec 15;23(24):6721-7. | ||||||||||
| Title: | Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells. | ||||||||||
| Author: | Mareddy, Jyoti|Nallapati, Suresh Babu|Anireddy, Jayasree|Devi, Yumnam Priyadarshini|Mangamoori, Lakshmi Narasu|Kapavarapu, Ravikumar|Pal, Sarbani | ||||||||||
| PMID: | 24215890 | ||||||||||
| 5. | |||||||||||
| Journal: | Arch Pharm (Weinheim). 2014 Sep;347(9):650-7. | ||||||||||
| Title: | Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies. | ||||||||||
| Author: | Abdel-Rahman, Hamdy M|Abdel-Aziz, Mohamed|Canzoneri, Joshua C|Gary, Bernard D|Piazza, Gary A | ||||||||||
| PMID: | 24985336 | ||||||||||
| 6. | |||||||||||
| Journal: | Anticancer Res. 2014 Aug;34(8):4551-5. | ||||||||||
| Title: | Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture. | ||||||||||
| Author: | Tsunoda, Toshiyuki|Ishikura, Shuhei|Doi, Keiko|Matsuzaki, Hiroshi|Iwaihara, Yuri|Shirasawa, Senji | ||||||||||
| PMID: | 25075098 | ||||||||||
| 7. | |||||||||||
| Journal: | BMC Cancer. 2016 Dec 7;16(1):938. | ||||||||||
| Title: | Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia. | ||||||||||
| Author: | Mahmood, Badar|Damm, Morten Matthiesen Bach|Jensen, Thorbjorn Soren Ronn|Backe, Marie Balslev|Dahllof, Mattias Salling|Poulsen, Steen Seier|Bindslev, Niels|Hansen, Mark Berner | ||||||||||
| PMID: | 27927168 | ||||||||||
| 8. | |||||||||||
| Journal: | Int Immunopharmacol. 2018 Mar;56:36-42. | ||||||||||
| Title: | Roflumilast, type 4 phosphodiesterase inhibitor, attenuates inflammation in rats with ulcerative colitis via down-regulation of iNOS and elevation of cAMP. | ||||||||||
| Author: | El-Ashmawy, Nahla E|Khedr, Naglaa F|El-Bahrawy, Hoda A|El-Adawy, Samar A | ||||||||||
| PMID: | 29331766 | ||||||||||