Primary Site >> Colorectal Cancer

Gene >> PCSK6

Journal: J Biol Chem. 2001 Aug 17;276(33):30686-93. Epub 2001 Jun 11.
Title: Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
Author: Khatib, A M|Siegfried, G|Prat, A|Luis, J|Chretien, M|Metrakos, P|Seidah, N G
PMID: 11402025
Journal: J Clin Invest. 2003 Jun;111(11):1723-32.
Title: The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
Author: Siegfried, Geraldine|Basak, Ajoy|Cromlish, James A|Benjannet, Suzanne|Marcinkiewicz, Jadwiga|Chretien, Michel|Seidah, Nabil G|Khatib, Abdel-Majid
PMID: 12782675
Journal: Mol Reprod Dev. 2005 Dec;72(4):483-93.
Title: Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.
Author: St Germain, Carly|Croissandeau, Gilles|Mayne, Janice|Baltz, Jay M|Chretien, Michel|Mbikay, Majambu
PMID: 16163737
Journal: J Clin Invest. 2008 Jan;118(1):352-63.
Title: Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
Author: Scamuffa, Nathalie|Siegfried, Geraldine|Bontemps, Yannick|Ma, Liming|Basak, Ajoy|Cherel, Ghislaine|Calvo, Fabien|Seidah, Nabil G|Khatib, Abdel-Majid
PMID: 18064302