Primary Site >> Colorectal Cancer

Gene >> PCSK6

  • 2001
  • 2003
  • 2005
  • 2008
Ref: Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
PMID: 11402025
 Ref: The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
PMID: 12782675
 Ref: Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.
PMID: 16163737
 Ref: Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
PMID: 18064302