Primary Site >> Colorectal Cancer

Gene >> PARP1

Journal: Int J Biol Markers. 1987 May-Aug;2(2):95-100.
Title: A new ADP-ribosyltransferase in human serum: significance in cancer.
Author: Pohl, A L
PMID: 3132517
Journal: Gut. 1988 Dec;29(12):1680-6.
Title: Hydrogen peroxide induced adenosine diphosphate ribosyl transferase (ADPRT) response in patients with inflammatory bowel disease.
Author: Markowitz, M M|Rozen, P|Pero, R W|Tobi, M|Miller, D G
PMID: 3146530
Journal: Oncogene. 1998 Apr 9;16(14):1899-902.
Title: Abrogation of c-Raf expression induces apoptosis in tumor cells.
Author: Lau, Q C|Brusselbach, S|Muller, R
PMID: 9583688
Journal: Br J Cancer. 1998 May;77(10):1628-32.
Title: Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer.
Author: Cristovao, L|Lechner, M C|Fidalgo, P|Leitao, C N|Mira, F C|Rueff, J
PMID: 9635838
Journal: Cell Death Differ. 1998 Jul;5(7):623-36.
Title: The stress-response proteins poly(ADP-ribose) polymerase and NF-kappaB protect against bile salt-induced apoptosis.
Author: Payne, C M|Crowley, C|Washo-Stultz, D|Briehl, M|Bernstein, H|Bernstein, C|Beard, S|Holubec, H|Warneke, J
PMID: 10200517
Journal: Biochem Pharmacol. 1999 Jan 1;57(1):19-26.
Title: Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.
Author: Karczewski, J M|Peters, J G|Noordhoek, J
PMID: 9920281
Journal: Clin Cancer Res. 1999 Mar;5(3):665-72.
Title: Detection of poly(ADP-ribose) polymerase cleavage in response to treatment with topoisomerase I inhibitors: a potential surrogate end point to assess treatment effectiveness.
Author: Whitacre, C M|Zborowska, E|Willson, J K|Berger, N A
PMID: 10100720
Journal: Int J Oncol. 1999 May;14(5):979-85.
Title: Novel 19-nor-hexafluoride vitamin D3 analog (Ro 25-6760) inhibits human colon cancer in vitro via apoptosis.
Author: Evans, S R|Soldatenkov, V|Shchepotin, E B|Bogrash, E|Shchepotin, I B
PMID: 10200351
Journal: Cell Death Differ. 1999 Aug;6(8):729-35.
Title: Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP).
Author: Ruemmele, F M|Dionne, S|Qureshi, I|Sarma, D S|Levy, E|Seidman, E G
PMID: 10467346
Journal: Br J Cancer. 1999 Sep;81(2):294-9.
Title: Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells.
Author: Castano, E|Dalmau, M|Barragan, M|Pueyo, G|Bartrons, R|Gil, J
PMID: 10496355
Journal: Clin Cancer Res. 1999 Oct;5(10):2908-17.
Title: Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
Author: Liu, L|Taverna, P|Whitacre, C M|Chatterjee, S|Gerson, S L
PMID: 10537360
Journal: Anticancer Res. 1999 Sep-Oct;19(5B):4251-6.
Title: Antitumor activity and induction of apoptosis by water-soluble derivatives of 7 beta-hydroxycholesterol in human colon carcinoma cell lines.
Author: Maier, G|Bing, G|Falken, U|Wagner, E|Unger, C
PMID: 10628383
Journal: Clin Cancer Res. 2000 May;6(5):2021-7.
Title: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Author: Whitacre, C M|Feyes, D K|Satoh, T|Grossmann, J|Mulvihill, J W|Mukhtar, H|Oleinick, N L
PMID: 10815928
Journal: Int J Colorectal Dis. 2000 Apr;15(2):105-11.
Title: Role of caspase-3 in apoptosis of colon cancer cells induced by nonsteroidal anti-inflammatory drugs.
Author: Kim, W H|Yeo, M|Kim, M S|Chun, S B|Shin, E C|Park, J H|Park, I S
PMID: 10855553
Journal: Br J Cancer. 2000 Jun;82(12):1991-9.
Title: Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c-jun N-terminal kinase activity.
Author: Liu, B|Fang, M|Schmidt, M|Lu, Y|Mendelsohn, J|Fan, Z
PMID: 10864208
Journal: Cancer Lett. 2001 Jun 10;167(1):91-7.
Title: Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features.
Author: Shannon, B A|Iacopetta, B J
PMID: 11323103
Journal: Life Sci. 2001 Mar 16;68(17):2025-36.
Title: Prodigiosin-induced apoptosis in human colon cancer cells.
Author: Montaner, B|Perez-Tomas, R
PMID: 11388704
Journal: Int J Cancer. 2001 Aug 15;93(4):526-33.
Title: Induction of apoptosis in human colon carcinoma cells HT29 by sublethal cryo-injury: mediation by cytochrome c release.
Author: Hanai, A|Yang, W L|Ravikumar, T S
PMID: 11477556
Journal: Chem Res Toxicol. 2001 Aug;14(8):1090-6.
Title: 4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.
Author: Ji, C|Amarnath, V|Pietenpol, J A|Marnett, L J
PMID: 11511183
Journal: Anticancer Drugs. 2001 Oct;12(9):741-51.
Title: Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo.
Author: Guichard, S|Arnould, S|Hennebelle, I|Bugat, R|Canal, P
PMID: 11593056
Journal: Oncogene. 2002 Jan 17;21(3):337-46.
Title: Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author: Nam, Seon Young|Amoscato, Andrew A|Lee, Yong J
PMID: 11821946
Journal: Cancer Chemother Pharmacol. 2002 Jan;49(1):27-34.
Title: Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells.
Author: Feinman, Rena|Clarke, Kevin O|Harrison, Lawrence E
PMID: 11855750
Journal: Cancer Gene Ther. 2002 May;9(5):453-63.
Title: C-terminal deletion mutant p21(WAF1/CIP1) enhances E2F-1-mediated apoptosis in colon adenocarcinoma cells.
Author: Elliott, Mary Jane|Stilwell, Ariel|Dong, Yan Bin|Yang, Hai Liang|Wong, Sandra L|Wrightson, William R|Martin, Robert C G|McMasters, Kelly M
PMID: 11961668
Journal: J Nutr. 2002 Jul;132(7):1812-8.
Title: Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines.
Author: Avivi-Green, Carmel|Polak-Charcon, Sylvie|Madar, Zecharia|Schwartz, Betty
PMID: 12097652
Journal: Anticancer Res. 2002 May-Jun;22(3):1635-9.
Title: Tumor necrosis factor-alpha induces apoptosis associated with poly(ADP-ribose) polymerase cleavage in HT-29 colon cancer cells.
Author: Vaculova, Alena|Hofmanova, Jirina|Soucek, Karel|Kovarikova, Martina|Kozubik, Alois
PMID: 12168847
Journal: Int J Cancer. 2002 Sep 1;101(1):23-31.
Title: Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.
Author: Magrini, Roberta|Bhonde, Mandar R|Hanski, Marie-Luise|Notter, Michael|Scherubl, Hans|Boland, C Richard|Zeitz, Martin|Hanski, Christoph
PMID: 12209584
Journal: Carcinogenesis. 2002 Dec;23(12):2087-93.
Title: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.
Author: Liu, Jian-Jun|Nilsson, Ake|Oredsson, Stina|Badmaev, Vladimir|Zhao, Wan-Zhou|Duan, Rui-Dong
PMID: 12507932
Journal: Cancer Res Treat. 2002 Jun;34(3):212-7.
Title: Retinoic Acid Enhances Drug-Induced Cell Death in Anticancer Drug-Resistant Cell Lines.
Author: Whang, Young Mi|Kim, Yeul Hong|Shin, Sang Won|Kim, Byung Soo|Kim, Jun Suk|Yoo, Young Do|Park, Sun Hee
PMID: 26680865
Journal: Int J Cancer. 2003 Jan 20;103(3):360-9.
Title: Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction.
Author: Yang, Weng-Lang|Addona, Tommaso|Nair, Deepak G|Qi, Lixin|Ravikumar, T S
PMID: 12471619
Journal: Biochem Pharmacol. 2003 Jan 1;65(1):121-9.
Title: Influence of p53 and p21(WAF1) expression on sensitivity of cancer cells to cladribine.
Author: Galmarini, Carlos Maria|Voorzanger, Nathalie|Falette, Nicole|Jordheim, Lars|Cros, Emeline|Puisieux, Alain|Dumontet, Charles
PMID: 12473386
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2003 Mar;367(3):260-5.
Title: Apoptosis induction in human cancer cells by sungucine from Strychnos icaja root.
Author: Frederich, Michel|Bentires-Ali, Mohamed|Tits, Monique|Angenot, Luc|Heinen, Ernst|De Pauw-Gillet, Marie-Claire
PMID: 12644898
Journal: Mol Cancer Ther. 2003 Apr;2(4):371-82.
Title: Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly(ADP-ribose) polymerase inhibitor.
Author: Miknyoczki, Sheila J|Jones-Bolin, Susan|Pritchard, Sonya|Hunter, Kathryn|Zhao, Hugh|Wan, Weihua|Ator, Mark|Bihovsky, Ronald|Hudkins, Robert|Chatterjee, Sankar|Klein-Szanto, Andres|Dionne, Craig|Ruggeri, Bruce
PMID: 12700281
Journal: Int J Oncol. 2003 Aug;23(2):503-8.
Title: Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.
Author: Lee, Eun Ju|Park, Hye Geong|Kang, Ho Sung
PMID: 12851702
Journal: Clin Cancer Res. 2003 Jul;9(7):2711-8.
Title: Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors: chemopotentiation and pharmacological studies.
Author: Calabrese, Christopher R|Batey, Michael A|Thomas, Huw D|Durkacz, Barbara W|Wang, Lan-Zhen|Kyle, Suzanne|Skalitzky, Donald|Li, Janke|Zhang, Catherine|Boritzki, Theodore|Maegley, Karen|Calvert, Alan H|Hostomsky, Zdenek|Newell, David R|Curtin, Nicola J
PMID: 12855651
Journal: Oncol Rep. 2003 Nov-Dec;10(6):1723-8.
Title: Direct effects of octreotide, galanin and serotonin on human colon cancer cells.
Author: El-Salhy, Magdy|Starefeldt, Anna
PMID: 14534685
Journal: Cancer Sci. 2003 Oct;94(10):886-93.
Title: Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine.
Author: Aizawa, Shu|Ookawa, Keizou|Kudo, Toshihiro|Asano, Junpei|Hayakari, Makoto|Tsuchida, Shigeki
PMID: 14556662
Journal: Zhonghua Yi Xue Za Zhi. 2003 Nov 10;83(21):1895-9.
Title: [Suppression of HCT116 growth of cells by Gadd45].
Author: Tong, Tong|Song, Yong-mei|Fu, Ming|Dong, Li-jia|Jin, Shun-qian|Wu, Min|Zhan, Qi-min
PMID: 14642075
Journal: Planta Med. 2003 Dec;69(12):1091-5.
Title: Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines.
Author: Yang, Ling-Ling|Wang, Min-Chieh|Chen, Lih-Geeng|Wang, Ching-Chiung
PMID: 14750023
Journal: Carcinogenesis. 2004 Feb;25(2):219-27.
Title: Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization.
Author: Jackson, Steven J T|Singletary, Keith W
PMID: 14578157
Journal: Carcinogenesis. 2004 Feb;25(2):179-87.
Title: Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.
Author: Rashmi, Ramachandran|Kumar, Santhosh|Karunagaran, Devarajan
PMID: 14604899
Journal: Int J Cancer. 2004 Jan 20;108(3):464-72.
Title: Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells.
Author: Koizumi, Fumiaki|Kanzawa, Fumihiko|Ueda, Yutaka|Koh, Yasuhiro|Tsukiyama, Shoji|Taguchi, Fumiko|Tamura, Tomohide|Saijo, Nagahiro|Nishio, Kazuto
PMID: 14648715
Journal: Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title: Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author: Lee, Yong J|Song, Jae J|Kim, Jin H|Kim, Hyeong-Reh Choi|Song, Young K
PMID: 14729063
Journal: Bioorg Med Chem Lett. 2004 May 17;14(10):2433-7.
Title: Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
Author: White, Alex W|Curtin, Nicola J|Eastman, Brian W|Golding, Bernard T|Hostomsky, Zdenek|Kyle, Suzanne|Li, Jianke|Maegley, Karen A|Skalitzky, Donald J|Webber, Stephen E|Yu, Xiao-Hong|Griffin, Roger J
PMID: 15109627
Journal: Cell Res. 2004 Apr;14(2):117-24.
Title: LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.
Author: Zhang, Man Chao|Liu, Hong Peng|Demchik, Lisa L|Zhai, Yi Fan|Yang, Da Jun
PMID: 15115612
Journal: Toxicol Appl Pharmacol. 2004 Jun 1;197(2):84-95.
Title: Structurally related antitumor effects of flavanones in vitro and in vivo: involvement of caspase 3 activation, p21 gene expression, and reactive oxygen species production.
Author: Shen, Shing-Chuan|Ko, Ching Huai|Tseng, Shi-Wen|Tsai, Shu-Huei|Chen, Yen-Chou
PMID: 15163544
Journal: Pharmacol Res. 2004 Aug;50(2):201-7.
Title: Echinomycin and a novel analogue induce apoptosis of HT-29 cells via the activation of MAP kinases pathway.
Author: Park, Ju Youn|Park, Su Jung|Shim, Kwang Yong|Lee, Kyu Jae|Kim, Yun-Bong|Kim, Yong Hae|Kim, Soo Kie
PMID: 15177310
Journal: Int J Oncol. 2004 Sep;25(3):661-70.
Title: Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.
Author: Chen, Yen-Chou|Shen, Shing-Chuan|Chow, Jyh-Ming|Ko, Ching Huai|Tseng, Shih-Wen
PMID: 15289867
Journal: Carcinogenesis. 2004 Dec;25(12):2425-32. Epub 2004 Aug 12.
Title: Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells.
Author: Baek, Seung Joon|Kim, Jong-Sik|Jackson, Felix R|Eling, Thomas E|McEntee, Michael F|Lee, Seong-Ho
PMID: 15308587
Journal: J Cancer Res Clin Oncol. 2004 Dec;130(12):695-703. Epub 2004 Aug 31.
Title: Reduced levels of the adenomatous polyposis coli (APC) protein are associated with ceramide-induced apoptosis of colon cancer cells.
Author: Jaiswal, Aruna S|Narayan, Satya
PMID: 15340841
Journal: J Agric Food Chem. 2004 Oct 6;52(20):6330-7.
Title: Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells.
Author: Hsu, Ping-Chi|Huang, Yu-Ting|Tsai, Mei-Ling|Wang, Ying-Jan|Lin, Jen-Kun|Pan, Min-Hsiung
PMID: 15453709
Journal: Anticancer Res. 2004 Sep-Oct;24(5A):2885-91.
Title: EGF-receptor related protein causes cell cycle arrest and induces apoptosis of colon cancer cells in vitro and in vivo.
Author: Levi, Edi|Mohammad, Ramzi|Kodali, Udayini|Marciniak, Dorota|Reddy, Sudha|Aboukameel, Amro|Sarkar, Fazlul H|Kucuk, Omer|Rishi, Arun K|Majumdar, Adhip P N
PMID: 15517892
Journal: Int J Cancer. 2005 Jan 1;113(1):42-53.
Title: p21(Waf1/Cip1) and p53 are downstream effectors of protein kinase C delta in tumor suppression and differentiation in human colon cancer cells.
Author: Perletti, Gianpaolo|Marras, Emanuela|Dondi, Davide|Osti, Daniela|Congiu, Terenzio|Ferrarese, Roberto|de Eguileor, Magda|Tashjian, Armen H Jr
PMID: 15386430
Journal: Histol Histopathol. 2005 Jan;20(1):19-25.
Title: Effects of triple therapy with octreotide, galanin and serotonin on a human colon cancer cell line implanted in mice: comparison between different routes of administration.
Author: El-Salhy, M
PMID: 15578418
Journal: J Histochem Cytochem. 2005 Feb;53(2):229-35.
Title: Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa.
Author: Holubec, Hana|Payne, Claire M|Bernstein, Harris|Dvorakova, Katerina|Bernstein, Carol|Waltmire, Caroline N|Warneke, James A|Garewal, Harinder
PMID: 15684335
Journal: Biochem Pharmacol. 2005 Mar 1;69(5):831-9.
Title: Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53.
Author: Grosch, Sabine|Schilling, Karin|Janssen, Astrid|Maier, Thorsten J|Niederberger, Ellen|Geisslinger, Gerd
PMID: 15710360
Journal: Gastroenterology. 2005 Jun;128(7):1919-36.
Title: Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.
Author: Idogawa, Masashi|Yamada, Tesshi|Honda, Kazufumi|Sato, Satoshi|Imai, Kohzoh|Hirohashi, Setsuo
PMID: 15940627
Journal: Planta Med. 2005 Jun;71(6):501-7.
Title: Induction of apoptosis by Panduratin A isolated from Kaempferia pandurata in human colon cancer HT-29 cells.
Author: Yun, Jung-Mi|Kwon, Hoonjeong|Mukhtar, Hasan|Hwang, Jae-Kwan
PMID: 15971119
Journal: Mol Nutr Food Res. 2005 Sep;49(9):837-43.
Title: Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway.
Author: Pan, Lydia|Becker, Hans|Gerhauser, Clarissa
PMID: 15995977
Journal: Cancer Lett. 2005 Aug 26;226(2):115-21.
Title: The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells.
Author: Kapitza, Susanne|Jakupec, Michael A|Uhl, Maria|Keppler, Bernhard K|Marian, Brigitte
PMID: 16039951
Journal: Cancer Lett. 2005 Nov 8;229(1):43-8. Epub 2005 Jan 18.
Title: TRAIL and docosahexaenoic acid cooperate to induce HT-29 colon cancer cell death.
Author: Vaculova, Alena|Hofmanova, Jirina|Andera, Ladislav|Kozubik, Alois
PMID: 16157217
Journal: Cancer Biol Ther. 2005 Oct;4(10):1159-67. Epub 2005 Oct 23.
Title: Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Author: Caraglia, Michele|Marra, Monica|Budillon, Alfredo|Meo, Giuseppina|Ricciardiello, Filippo|Bismuto, Ettore|Brachelente, Giovanni|Francini, Guido|Giordano, Antonio|Correale, Pierpaolo|Abbruzzese, Alberto
PMID: 16294035
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4197-202.
Title: Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide cyclo(Phe-Pro) in HT-29 cells.
Author: Brauns, Seth Clint|Dealtry, Gill|Milne, Pieter|Naude, Ryno|Van de Venter, Maryna
PMID: 16309216
Journal: Cell Signal. 2006 Jun;18(6):882-8.
Title: A role for cyclic-GMP dependent protein kinase in anoikis.
Author: Hou, Yali|Wong, Elsie|Martin, Jessica|Schoenlein, Patricia V|Dostmann, Wolfgang R|Browning, Darren D
PMID: 16139477
Journal: Bioorg Med Chem. 2006 Apr 15;14(8):2498-506.
Title: Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents.
Author: Shin, Dae-Seop|Kim, Jong-Han|Lee, Su-Kyung|Han, Dong Cho|Son, Kwang-Hee|Kim, Hwan-Mook|Cheon, Hyae-Gyeong|Kim, Kwang-Rok|Sung, Nack-Do|Lee, Seung Jae|Kang, Sung Kwon|Kwon, Byoung-Mog
PMID: 16343908
Journal: Int J Oncol. 2006 Feb;28(2):559-65.
Title: Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate.
Author: Stokrova, Jitka|Sloncova, Eva|Sovova, Vlasta|Kucerova, Dana|Zila, Vojtech|Tureckova, Jolana|Vojtechova, Martina|Korb, Jan|Tuhackova, Zdena
PMID: 16391813
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Mutat Res. 2006 Jul 25;599(1-2):76-87. Epub 2006 Feb 24.
Title: Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae.
Author: Pappa, Gerlinde|Lichtenberg, Maike|Iori, Renato|Barillari, Jessica|Bartsch, Helmut|Gerhauser, Clarissa
PMID: 16500682
Journal: Oncogene. 2006 Nov 9;25(53):7070-7. Epub 2006 May 22.
Title: Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis.
Author: Deng, R|Li, W|Guan, Z|Zhou, J-M|Wang, Y|Mei, Y-P|Li, M-T|Feng, G-K|Huang, W|Liu, Z-C|Han, Y|Zeng, Y-X|Zhu, X-F
PMID: 16715131
Journal: Carcinogenesis. 2006 Dec;27(12):2455-63.
Title: An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.
Author: Lee, Hyo-Jeong|Lee, Eun-Ok|Rhee, Yun-Hee|Ahn, Kyoo Seok|Li, Guang-Xun|Jiang, Cheng|Lu, Junxuan|Kim, Sung-Hoon
PMID: 16777983
Journal: Bioorg Med Chem Lett. 2006 Sep 1;16(17):4554-8.
Title: Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers.
Author: Tai, Vincent W-F|Sperandio, David|Shelton, Emma J|Litvak, Joane|Pararajasingham, Keith|Cebon, Ben|Lohman, Julia|Eksterowicz, John|Kantak, Seema|Sabbatini, Peter|Brown, Cindy|Zeitz, Jennifer|Reed, Chris|Maske, Bill|Graupe, Doris|Estevez, Alberto|Oeh, Jason
PMID: 16784854
Journal: Anticancer Res. 2006 Jul-Aug;26(4B):3033-41.
Title: Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest.
Author: Flis, S|Soltysiak-Pawluczuk, D|Jedrych, A|Jastrzebski, Z|Remiszewska, M|Splawinski, J
PMID: 16886631
Journal: Br J Cancer. 2006 Sep 18;95(6):735-43.
Title: EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer.
Author: Youssef, M M S|Symonds, P|Ellis, I O|Murray, J C
PMID: 16929248
Journal: Exp Mol Med. 2006 Dec 31;38(6):616-24.
Title: Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway?
Author: Kim, Hak-Ryul|Kim, Eun-Jung|Yang, Sei-Hoon|Jeong, Eun-Taik|Park, Channy|Lee, Jae-Hyung|Youn, Myung-Ja|So, Hong-Seob|Park, Raekil
PMID: 17202837
Journal: Cancer Chemother Pharmacol. 2007 Jul;60(2):275-83.
Title: The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo.
Author: Tumber, Anthony|Collins, Laura S|Petersen, Kamille Dumong|Thougaard, Annemette|Christiansen, Sanne J|Dejligbjerg, Marielle|Jensen, Peter Buhl|Sehested, Maxwell|Ritchie, James W A
PMID: 17124594
Journal: Apoptosis. 2007 Feb;12(2):423-31.
Title: Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
Author: Lim, Soo-Jeong|Lee, Young-Ju|Park, Dae-Hun|Lee, Eunmyong|Choi, Moon-Kyung|Park, Wanseo|Chun, Kyung-Hee|Choi, Han-Gon|Cho, Jung Sik
PMID: 17191116
Journal: J Cell Biochem. 2007 Jun 1;101(3):619-30.
Title: Effect of hyperthermia on TRAIL-induced apoptotic death in human colon cancer cells: development of a novel strategy for regional therapy.
Author: Yoo, Jinsang|Lee, Yong J
PMID: 17212362
Journal: Eur J Pharmacol. 2007 Mar 15;559(1):1-13.
Title: Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
Author: Ko, Joshua K S|Leung, Wan C|Ho, Wai K|Chiu, Pauline
PMID: 17258704
Journal: Apoptosis. 2007 Apr;12(4):685-94.
Title: Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient mice.
Author: Dimas, Konstantinos|Hatziantoniou, Sophia|Tseleni, Sophia|Khan, Humaira|Georgopoulos, Aristidis|Alevizopoulos, Konstantinos|Wyche, James H|Pantazis, Panayotis|Demetzos, Costas
PMID: 17260186
Journal: Cancer Res. 2007 Feb 1;67(3):1395-404.
Title: Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma.
Author: Berndt, Sonja I|Huang, Wen-Yi|Fallin, M Daniele|Helzlsouer, Kathy J|Platz, Elizabeth A|Weissfeld, Joel L|Church, Timothy R|Welch, Robert|Chanock, Stephen J|Hayes, Richard B
PMID: 17283177
Journal: Endocr Relat Cancer. 2007 Mar;14(1):153-67.
Title: Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation.
Author: Galluzzo, Paola|Caiazza, Francesco|Moreno, Sandra|Marino, Maria
PMID: 17395984
Journal: World J Gastroenterol. 2007 Apr 7;13(13):1947-52.
Title: Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells.
Author: Lim, Yun-Jeong|Rhee, Jong-Chul|Bae, Young-Mee|Chun, Wan-Joo
PMID: 17461495
Journal: Biochem Pharmacol. 2007 Aug 1;74(3):392-406.
Title: p53 dependent and independent sensitivity to oxaliplatin of colon cancer cells.
Author: Toscano, Florent|Parmentier, Beatrice|Fajoui, Zineb El|Estornes, Yann|Chayvialle, Jean-Alain|Saurin, Jean-Christophe|Abello, Jacques
PMID: 17559811
Journal: Ai Zheng. 2007 Jun;26(6):566-71.
Title: [Inhibitory effect of 5-aminoisoquinolinone on PARP activity in colon carcinoma cell line HT-29].
Author: Hao, Lan-Xiang|Wang, Ya-Lan|Cai, Li|Li, Yuan-Yuan
PMID: 17562258
Journal: Int J Cancer. 2007 Oct 15;121(8):1670-9.
Title: Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells.
Author: Ko, Ching-Huai|Shen, Shing-Chuan|Yang, Liang-Yo|Lin, Cheng-Wei|Chen, Yen-Chou
PMID: 17597109
Journal: Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author: Hsu, Wen-Hsiu|Hsieh, Yih-Shou|Kuo, Hsing-Chun|Teng, Chun-Yuh|Huang, Hai-I|Wang, Chau-Jong|Yang, Shun-Fa|Liou, Yi-Sheng|Kuo, Wu-Hsien
PMID: 17673978
Journal: Exp Mol Pathol. 2007 Dec;83(3):341-6. Epub 2007 Sep 7.
Title: Soluble CD44 secretion contributes to the acquisition of aggressive tumor phenotype in human colon cancer cells.
Author: Subramaniam, Venkateswaran|Gardner, Helena|Jothy, Serge
PMID: 17945213
Journal: J Surg Res. 2007 Nov;143(1):58-65.
Title: Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer.
Author: Hogan, Fawn S|Krishnegowda, Naveen K|Mikhailova, Margarita|Kahlenberg, Morton S
PMID: 17950073
Journal: Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2363-72.
Title: DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study.
Author: Stern, Mariana C|Conti, David V|Siegmund, Kimberly D|Corral, Roman|Yuan, Jian-Min|Koh, Woon-Puay|Yu, Mimi C
PMID: 18006925
Journal: Cancer Chemother Pharmacol. 2008 Feb;61(2):189-201.
Title: Cell death in response to antimetabolites directed at thymidylate synthase.
Author: Barbour, Karen W|Berger, Franklin G
PMID: 17396263
Journal: J Cell Biochem. 2008 Jan 1;103(1):98-109.
Title: Effect of hyperthermia and chemotherapeutic agents on TRAIL-induced cell death in human colon cancer cells.
Author: Yoo, Jinsang|Lee, Yong J
PMID: 17520700
Journal: Chem Biol Interact. 2008 Jan 10;171(1):45-56.
Title: In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells.
Author: Verma, Monika|Singh, Shashank K|Bhushan, Shashi|Sharma, V K|Datt, Prabhu|Kapahi, B K|Saxena, A K
PMID: 17935706
Journal: Cancer Immunol Immunother. 2008 Jun;57(6):871-81. Epub 2007 Nov 20.
Title: Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.
Author: Shebzukhov, Yuriy V|Lavrik, Inna N|Karbach, Julia|Khlgatian, Svetlana V|Koroleva, Ekaterina P|Belousov, Pavel V|Kashkin, Kirill N|Knuth, Alexander|Jager, Elke|Chi, Nai-Wen|Kuprash, Dmitry V|Nedospasov, Sergei A
PMID: 18026951
Journal: J Agric Food Chem. 2008 Feb 13;56(3):875-83.
Title: Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.
Author: Papi, Alessio|Orlandi, Marina|Bartolini, Giovanna|Barillari, Jessica|Iori, Renato|Paolini, Moreno|Ferroni, Fiammetta|Grazia Fumo, Maria|Pedulli, Gian Franco|Valgimigli, Luca
PMID: 18189352
Journal: Clin Cancer Res. 2008 Mar 15;14(6):1788-96.
Title: Irinotecan pharmacogenetics: influence of pharmacodynamic genes.
Author: Hoskins, Janelle M|Marcuello, Eugenio|Altes, Albert|Marsh, Sharon|Maxwell, Taylor|Van Booven, Derek J|Pare, Laia|Culverhouse, Robert|McLeod, Howard L|Baiget, Montserrat
PMID: 18347181
Journal: Exp Mol Pathol. 2008 Jun;84(3):230-3.
Title: Curcumin induces apoptosis in HCT-116 human colon cancer cells in a p21-independent manner.
Author: Watson, Jane L|Hill, Richard|Lee, Patrick W|Giacomantonio, Carman A|Hoskin, David W
PMID: 18423603
Journal: Biochem Pharmacol. 2008 Jun 15;75(12):2345-55.
Title: Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw|Lee, Yong J
PMID: 18455702
Journal: Carcinogenesis. 2008 Jun;29(6):1139-47.
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
Author: Lei, Ping|Abdelrahim, Maen|Cho, Sung Dae|Liu, Shengxi|Chintharlapalli, Sudhakar|Safe, Stephen
PMID: 18460448
Journal: Carcinogenesis. 2008 Jul;29(7):1407-14.
Title: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Shastri, Yogesh M|Steinhilber, Dieter|Schroder, Oliver|Stein, Jurgen
PMID: 18544567
Journal: Cancer Invest. 2008 Aug;26(7):708-17.
Title: Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.
Author: Au-Yeung, Kathy Ka-Wai|Liu, Po-Ling|Chan, Cecilia|Wu, Wing-Yee|Lee, Susanna Sau-Tuen|Ko, Joshua Ka-Shun
PMID: 18608213
Journal: J Agric Food Chem. 2008 Sep 10;56(17):7823-30.
Title: Kaiware Daikon (Raphanus sativus L.) extract: a naturally multipotent chemopreventive agent.
Author: Barillari, Jessica|Iori, Renato|Papi, Alessio|Orlandi, Marina|Bartolini, Giovanna|Gabbanini, Simone|Pedulli, Gian Franco|Valgimigli, Luca
PMID: 18665601
Journal: Cancer Biol Ther. 2008 Nov;7(11):1765-73. Epub 2008 Nov 5.
Title: Anti colon cancer components from Lebanese sage (Salvia libanotica) essential oil: Mechanistic basis.
Author: Itani, Wafica S|El-Banna, Sarah H|Hassan, Saadia B|Larsson, Rolf L|Bazarbachi, Ali|Gali-Muhtasib, Hala U
PMID: 18787402
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title: [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author: Zhu, Hong-Bo|Huang, Xue-Feng|Hu, Jing-Zi|Zhou, Wei|Chen, Wei|Chen, Lin-Lin|He, Chao
PMID: 18788624
Journal: Cancer Lett. 2009 Jan 8;273(1):98-106.
Title: Combined treatment of Caco-2 cells with butyrate and mesalazine inhibits cell proliferation and reduces Survivin protein level.
Author: Schwab, Markus|Reynders, Veerle|Steinhilber, Dieter|Stein, Jurgen
PMID: 18774638
Journal: Pathol Oncol Res. 2009 Sep;15(3):323-8.
Title: Effect of poly (ADP-ribose) polymerase-1 inhibition on the proliferation of murine colon carcinoma CT26 cells.
Author: Cai, Li|Threadgill, Michael D|Wang, Yalan|Li, Ming
PMID: 18989759
Journal: Eur J Haematol. 2009 Mar;82(3):165-75.
Title: Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.
Author: Minke, Katharina Salome|Staib, Peter|Puetter, Adriane|Gehrke, Iris|Gandhirajan, Rajesh Kumar|Schlosser, Axel|Schmitt, Esther Katharina|Hallek, Michael|Kreuzer, Karl-Anton
PMID: 19067737
Journal: Ann Surg Oncol. 2009 Mar;16(3):761-71.
Title: Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells.
Author: Li, Jie|Hou, Ni|Faried, Ahmad|Tsutsumi, Soichi|Takeuchi, Toshiyuki|Kuwano, Hiroyuki
PMID: 19116755
Journal: Biochem Biophys Res Commun. 2009 Feb 6;379(2):514-8.
Title: Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.
Author: Radanyi, Christine|Le Bras, Gaelle|Bouclier, Celine|Messaoudi, Samir|Peyrat, Jean-Francois|Brion, Jean-Daniel|Alami, Mouad|Renoir, Jack-Michel
PMID: 19118525
Journal: Int J Mol Med. 2009 Feb;23(2):189-96.
Title: Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line.
Author: Auyeung, Kathy Ka-wai|Law, Pui-ching|Ko, Joshua Ka-shun
PMID: 19148542
Journal: Cancer Sci. 2009 Mar;100(3):503-13.
Title: Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential.
Author: Lee, Jenq-Chang|Su, Chun-Li|Chen, Lin-Lin|Won, Shen-Jeu
PMID: 19154411
Journal: J Cell Biochem. 2009 Apr 15;106(6):1113-22.
Title: Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw-Jerzy|Lee, Yong J
PMID: 19229860
Journal: Br J Nutr. 2009 Sep;102(5):663-71.
Title: Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis.
Author: Munjal, Umang|Glei, Michael|Pool-Zobel, Beatrice Louise|Scharlau, Daniel
PMID: 19250571
Journal: Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8.
Title: Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
Author: Lim, Do Y|Park, Jung Han Yoon
PMID: 19264955
Journal: BMC Cancer. 2009 Mar 30;9:99.
Title: New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.
Author: Cen, Ling|Hutzen, Brian|Ball, Sarah|DeAngelis, Stephanie|Chen, Chun-Liang|Fuchs, James R|Li, Chenglong|Li, Pui-Kai|Lin, Jiayuh
PMID: 19331692
Journal: Int J Biochem Cell Biol. 2009 Oct;41(10):1890-8.
Title: Study of the effects of a new pyrazolecarboxamide: changes in mitochondria and induction of apoptosis.
Author: Giansanti, Vincenzo|Camboni, Tania|Piscitelli, Francesco|Prosperi, Ennio|La Regina, Giuseppe|Lazze, Maria C|Santin, Giada|Silvestri, Romano|Scovassi, Anna I
PMID: 19379827
Journal: Int J Cancer. 2009 Sep 1;125(5):1082-91.
Title: A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene.
Author: Auyeung, Kathy K W|Cho, Chi-Hin|Ko, Joshua K S
PMID: 19384947
Journal: Biomed Environ Sci. 2009 Feb;22(1):76-85.
Title: Potential mechanisms involved in ceramide-induced apoptosis in human colon cancer HT29 cells.
Author: Wang, Jing|Lv, Xiao-Wen|Du, Yu-Guo
PMID: 19462692
Journal: Pathobiology. 2009 May;76(3):108-16.
Title: Poly(ADP-ribose) polymerase inhibition down-regulates expression of metastasis-related genes in CT26 colon carcinoma cells.
Author: Li, Ming|Threadgill, Michael D|Wang, Yalan|Cai, Li|Lin, Xiao
PMID: 19468250
Journal: Int J Cancer. 2009 Sep 1;125(5):996-1003.
Title: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
Author: Santoro, Antonietta|Pisanti, Simona|Grimaldi, Claudia|Izzo, Angelo A|Borrelli, Francesca|Proto, Maria C|Malfitano, Anna M|Gazzerro, Patrizia|Laezza, Chiara|Bifulco, Maurizio
PMID: 19479993
Journal: Arch Physiol Biochem. 2009 Jul;115(3):127-36.
Title: Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signalling in colorectal cancer cells.
Author: Seti, Hila|Leikin-Frenkel, Alicia|Werner, Haim
PMID: 19480565
Journal: J Surg Oncol. 2009 Aug 1;100(2):149-58.
Title: Radiosensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate.
Author: Gao, Xiaohuan|Saha, Debabrata|Kapur, Payal|Anthony, Thomas|Livingston, Edward H|Huerta, Sergio
PMID: 19507186
Journal: J Leukoc Biol. 2009 Sep;86(3):599-607.
Title: Ethyl pyruvate administration inhibits hepatic tumor growth.
Author: Liang, Xiaoyan|Chavez, Antonio Romo de Vivar|Schapiro, Nicole E|Loughran, Patricia|Thorne, Stephen H|Amoscato, Andrew A|Zeh, Herbert J|Beer-Stolz, Donna|Lotze, Michael T|de Vera, Michael E
PMID: 19584311
Journal: Biochem Pharmacol. 2009 Nov 1;78(9):1224-32.
Title: 2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules.
Author: Li, Haitao|Wu, William Ka Kei|Zheng, Zongping|Che, Chun Tao|Yu, Le|Li, Zhi Jie|Wu, Ya Chun|Cheng, Ka-Wing|Yu, Jun|Cho, Chi Hin|Wang, Mingfu
PMID: 19591809
Journal: Proteomics. 2009 Jul;9(13):3535-48.
Title: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Author: Pirnia, Farzaneh|Pawlak, Michael|Thallinger, Gerhard G|Gierke, Berthold|Templin, Markus F|Kappeler, Andi|Betticher, Daniel C|Gloor, Beat|Borner, Markus M
PMID: 19609961
Journal: Ann N Y Acad Sci. 2009 Aug;1171:538-44.
Title: Green tea catechin controls apoptosis in colon cancer cells by attenuation of H2O2-stimulated COX-2 expression via the AMPK signaling pathway at low-dose H2O2.
Author: Park, In-Ja|Lee, Yun-Kyoung|Hwang, Jin-Taek|Kwon, Dae-Young|Ha, Joohun|Park, Ock Jin
PMID: 19723101
Journal: Cell Cycle. 2009 Oct 1;8(19):3149-56. Epub 2009 Oct 3.
Title: GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells.
Author: Hohla, Florian|Buchholz, Stefan|Schally, Andrew V|Seitz, Stefan|Rick, Ferenc G|Szalontay, Luca|Varga, Jozsef L|Zarandi, Marta|Halmos, Gabor|Vidaurre, Irving|Krishan, Awtar|Kurtoglu, Metin|Chandna, Sudhir|Aigner, Elmar|Datz, Christian
PMID: 19755849
Journal: Biol Pharm Bull. 2009 Oct;32(10):1760-4.
Title: Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells.
Author: Hyun, Jae-Hee|Kim, Sang-Cheol|Kang, Jung-Il|Kim, Min-Kyoung|Boo, Hye-Jin|Kwon, Jung-Mi|Koh, Young-Sang|Hyun, Jin-Won|Park, Deok-Bae|Yoo, Eun-Sook|Kang, Hee-Kyoung
PMID: 19801840
Journal: Ann Pathol. 2009 Oct;29(5):370-5.
Title: [Detection of apoptosis in vivo: comparison of different methods in histological sections of subcutaneous xenografts of HT29 human colon adenocarcinoma].
Author: Bressenot, Aude|Zimmer, Olivia|Marchal, Sophie|Gauchotte, Guillaume|Montagne, Karine|Plenat, Francois
PMID: 20004835
Journal: Photochem Photobiol Sci. 2009 Dec;8(12):1716-23.
Title: Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.
Author: Jendzelovsky, Rastislav|Mikes, Jaromir|Koval', Jan|Soucek, Karel|Prochazkova, Jirina|Kello, Martin|Sackova, Veronika|Hofmanova, Jirina|Kozubik, Alois|Fedorocko, Peter
PMID: 20024169
Journal: J Nutrigenet Nutrigenomics. 2009;2(6):273-9.
Title: Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study.
Author: Stern, Mariana C|Butler, Lesley M|Corral, Roman|Joshi, Amit D|Yuan, Jian-Min|Koh, Woon-Puay|Yu, Mimi C
PMID: 20559012
Journal: Cancer Lett. 2010 Jul 1;293(1):23-30.
Title: Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
Author: Choi, Sujin|Choi, Yunjin|Dat, Nguyen Tien|Hwangbo, Cheol|Lee, Jung Joon|Lee, Jeong-Hyung
PMID: 20056314
Journal: Cancer Biol Ther. 2010 May 1;9(9):699-709. Epub 2010 May 8.
Title: Stathmin/oncoprotein 18, a microtubule regulatory protein, is required for survival of both normal and cancer cell lines lacking the tumor suppressor, p53.
Author: Carney, Bruce K|Cassimeris, Lynne
PMID: 20200495
Journal: Endocr Relat Cancer. 2010 Jun 1;17(2):351-60.
Title: Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.
Author: Algire, Carolyn|Amrein, Lilian|Zakikhani, Mahvash|Panasci, Lawrence|Pollak, Michael
PMID: 20228137
Journal: Cell Signal. 2010 Aug;22(8):1214-21.
Title: RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance.
Author: Hadj-Slimane, Reda|Pamonsinlapatham, Perayot|Herbeuval, Jean-Philippe|Garbay, Christiane|Lepelletier, Yves|Raynaud, Francoise
PMID: 20362665
Journal: Anticancer Res. 2010 Mar;30(3):785-92.
Title: Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
Author: Gao, Xiaohua|Deeb, Dorrah|Hao, Jiang|Liu, Yongbo|Arbab, Ali S|Dulchavsky, Scott A|Gautam, Subhash C
PMID: 20392997
Journal: Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S244-52.
Title: Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells.
Author: Qiu, Peiju|Dong, Ping|Guan, Huashi|Li, Shiming|Ho, Chi-Tang|Pan, Min-Hsiung|McClements, David Julian|Xiao, Hang
PMID: 20397199
Journal: Eur J Pharmacol. 2010 Jul 10;637(1-3):55-61.
Title: 3,3',4,5,5'-Pentahydroxy-trans-stilbene, a resveratrol derivative, induces apoptosis in colorectal carcinoma cells via oxidative stress.
Author: Li, Haitao|Wu, William Ka Kei|Zheng, Zongping|Che, Chun Tao|Li, Zhi Jie|Xu, Dan Dan|Wong, Clover Ching Man|Ye, Cai Guo|Sung, Joseph Jao Yiu|Cho, Chi Hin|Wang, Mingfu
PMID: 20399769
Journal: Anticancer Res. 2010 Apr;30(4):1183-8.
Title: LA-12 overcomes confluence-dependent resistance of HT-29 colon cancer cells to Pt (II) compounds.
Author: Svihalkova-Sindlerova, Lenka|Foltinova, Vendula|Vaculova, Alena|Horvath, Viktor|Soucek, Karel|Sova, Petr|Hofmanova, Jirina|Kozubik, Alois
PMID: 20530425
Journal: J Cell Biochem. 2010 Aug 1;110(5):1073-81.
Title: Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors.
Author: Alcala, Marco A Jr|Park, Kyungsoo|Yoo, Jinsang|Lee, Dae-Hee|Park, Bae-Hang|Lee, Byeong-Chel|Bartlett, David L|Lee, Yong J
PMID: 20544795
Journal: Toxicol In Vitro. 2010 Sep;24(6):1599-609.
Title: Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa.
Author: Pal, Harish Chandra|Sehar, Irum|Bhushan, Shashi|Gupta, Bishan Dutt|Saxena, Ajit Kumar
PMID: 20600805
Journal: Toxicol In Vitro. 2010 Sep;24(6):1546-53.
Title: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells.
Author: Go, Hiroe|Hwang, Hye-Jung|Nam, Taek-Jeong
PMID: 20615460
Journal: J Ethnopharmacol. 2010 Sep 15;131(2):396-403.
Title: Cytotoxicity and bioavailability studies on a decoction of Oldenlandia diffusa and its fractions separated by HPLC.
Author: Ganbold, Munkhchimeg|Barker, James|Ma, Ren|Jones, Lucy|Carew, Mark
PMID: 20633624
Journal: Surgery. 2010 Aug;148(2):346-53.
Title: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
Author: Huerta, Sergio|Gao, Xiaohuan|Livingston, Edward H|Kapur, Payal|Sun, Haizhou|Anthony, Thomas
PMID: 20633731
Journal: Biochem Pharmacol. 2010 Nov 1;80(9):1356-64.
Title: Inhibition of cell growth and potentiation of tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis by a phenanthroindolizidine alkaloid antofine in human colon cancer cells.
Author: Min, Hye-Young|Chung, Hwa-Jin|Kim, Eun-Hye|Kim, Sanghee|Park, Eun-Jung|Lee, Sang Kook
PMID: 20674553
Journal: Anticancer Res. 2010 Jul;30(7):2531-8.
Title: Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells.
Author: Seetharam, Raviraja N|Sood, Arjun|Basu-Mallick, Atrayee|Augenlicht, Leonard H|Mariadason, John M|Goel, Sanjay
PMID: 20682979
Journal: BMC Gastroenterol. 2010 Aug 22;10:96.
Title: Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
Author: Kim, Eun Ji|Park, So Young|Lee, Jae-Yong|Park, Jung Han Yoon
PMID: 20727207
Journal: Bioorg Med Chem Lett. 2010 Dec 1;20(23):7110-5.
Title: Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities.
Author: Liang, Chun|Ding, Yan|Nguyen, Huu Tung|Kim, Jeong-Ah|Boo, Hye-Jin|Kang, Hee-Kyoung|Nguyen, Mahn Cuong|Kim, Young Ho
PMID: 20951582
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Dec;19(12):3167-73.
Title: Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.
Author: Brevik, Asgeir|Joshi, Amit D|Corral, Roman|Onland-Moret, N Charlotte|Siegmund, Kimberly D|Le Marchand, Loic|Baron, John A|Martinez, Maria Elena|Haile, Robert W|Ahnen, Dennis J|Sandler, Robert S|Lance, Peter|Stern, Mariana C
PMID: 21037106
Journal: Oncol Rep. 2010 Dec;24(6):1509-14.
Title: Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts.
Author: Na, Young-Soon|Kim, Seung-Mi|Jung, Kyung-Ah|Yang, Soo-Jin|Hong, Yong Sang|Ryu, Min-Hee|Ro, Seonggu|Cho, Dong-Hyung|Kim, Jin Cheon|Jin, Dong-Hoon|Lee, Jung Shin|Kim, Tae Won
PMID: 21042746
Journal: Korean J Physiol Pharmacol. 2010 Dec;14(6):391-7.
Title: Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT116 Human Colon Cancer Cells; Involvement of Reactive Oxygen Species.
Author: Kim, Kyung-Chan|Lee, Chuhee
PMID: 21311680
Journal: Mol Med Rep. 2010 Sep-Oct;3(5):825-31.
Title: 20(S)-Ginsenoside Rg3-induced apoptosis in HT-29 colon cancer cells is associated with AMPK signaling pathway.
Author: Yuan, Hai-Dan|Quan, Hai-Yan|Zhang, Ya|Kim, Sung Hoon|Chung, Sung-Hyun
PMID: 21472321
Journal: Int J Mol Sci. 2010;11(12):4916-31.
Title: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells.
Author: Lee, In Kyung|Kang, Kyoung Ah|Lim, Chae Moon|Kim, Ki Cheon|Kim, Hee Sun|Kim, Dong Hyun|Kim, Bum Joon|Chang, Weon Young|Choi, Jae Hyuck|Hyun, Jin Won
PMID: 21614182
Journal: Cancer Lett. 2011 Jan 1;300(1):96-104.
Title: Securin depletion sensitizes human colon cancer cells to fisetin-induced apoptosis.
Author: Yu, Sz-Hsien|Yang, Pei-Ming|Peng, Chih-Wen|Yu, Yi-Chu|Chiu, Shu-Jun
PMID: 20974518
Journal: Cell Biol Int. 2011 Jun;35(6):607-15.
Title: Apoptotic effect of eugenol in human colon cancer cell lines.
Author: Jaganathan, Saravana Kumar|Mazumdar, Abhijit|Mondhe, Dilip|Mandal, Mahitosh
PMID: 21044050
Journal: Oncogene. 2011 Mar 10;30(10):1205-12.
Title: Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells.
Author: Samuel, S|Fan, F|Dang, L H|Xia, L|Gaur, P|Ellis, L M
PMID: 21057529
Journal: J Appl Microbiol. 2011 Jan;110(1):304-13.
Title: Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines.
Author: Choi, E J|Park, J-S|Kim, Y-J|Jung, J-H|Lee, J K|Kwon, H C|Yang, H O
PMID: 21122037
Journal: Technol Cancer Res Treat. 2011 Feb;10(1):85-93.
Title: High energy shock waves and 5-aminolevulinic for sonodynamic therapy: effects in a syngeneic model of colon cancer.
Author: Serpe, L|Canaparo, R|Berta, L|Bargoni, A|Zara, G P|Frairia, R
PMID: 21214291
Journal: JOP. 2011 Mar 9;12(2):120-2.
Title: Translational research in pancreatic cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011.
Author: Strimpakos, Alexios S|Syrigos, Konstantinos N|Saif, Muhammad Wasif
PMID: 21386635
Journal: Mol Carcinog. 2011 Nov;50(11):884-900.
Title: Functional characterization of peroxisome proliferator-activated receptor-beta/delta expression in colon cancer.
Author: Foreman, Jennifer E|Chang, Wen-Chi L|Palkar, Prajakta S|Zhu, Bokai|Borland, Michael G|Williams, Jennie L|Kramer, Lance R|Clapper, Margie L|Gonzalez, Frank J|Peters, Jeffrey M
PMID: 21400612
Journal: Mol Nutr Food Res. 2011 Apr;55(4):613-22.
Title: The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones.
Author: Qiu, Peiju|Guan, Huashi|Dong, Ping|Li, Shiming|Ho, Chi-Tang|Pan, Min-Hsiung|McClements, David Julian|Xiao, Hang
PMID: 21462329
Journal: Mutat Res. 2011 Jul 1;712(1-2):40-8.
Title: Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1.
Author: Vernole, Patrizia|Muzi, Alessia|Volpi, Antonio|Terrinoni, Alessandro|Dorio, Annalisa Susanna|Tentori, Lucio|Shah, Girish M|Graziani, Grazia
PMID: 21570414
Journal: J Exp Clin Cancer Res. 2011 May 17;30:59.
Title: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity.
Author: Ritchie, Shawn A|Jayasinghe, Dushmanthi|Davies, Gerald F|Ahiahonu, Pearson|Ma, Hong|Goodenowe, Dayan B
PMID: 21586136
Journal: Hum Mol Genet. 2011 Aug 15;20(16):3241-55.
Title: DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.
Author: Loughery, Jayne E P|Dunne, Philip D|O'Neill, Karla M|Meehan, Richard R|McDaid, Jennifer R|Walsh, Colum P
PMID: 21636528
Journal: J Exp Ther Oncol. 2011;9(2):119-27.
Title: Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.
Author: Gao, Xiaohua|Deeb, Dorrah|Liu, Patricia|Liu, Yongbo|Arbab-Ali, Syed|Dulchavsky, Scott A|Gautam, Subhash C
PMID: 21699019
Journal: Hum Cell. 2011 Sep;24(3):121-6.
Title: Enormous influence of TNIK knockdown on intracellular signals and cell survival.
Author: Gui, Jinghua|Yang, Baotian|Wu, Jinyun|Zhou, Xiumei
PMID: 21710359
Journal: Int J Oncol. 2011 Oct;39(4):821-31.
Title: Photolon --photosensitization induces apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes.
Author: Ali-Seyed, Mohamed|Bhuvaneswari, Ramaswamy|Soo, Khee Chee|Olivo, Malini
PMID: 21725591
Journal: Biosci Biotechnol Biochem. 2011;75(7):1306-11.
Title: Isoegomaketone induces apoptosis through caspase-dependent and caspase-independent pathways in human DLD1 cells.
Author: Cho, Byoung Ok|Jin, Chang Hyun|Park, Yong Dae|Ryu, Hyung Won|Byun, Myung Woo|Seo, Kwon Il|Jeong, Il Yun
PMID: 21737934
Journal: Food Chem Toxicol. 2011 Sep;49(9):2445-52.
Title: A novel non-aromatic B-ring flavonoid: isolation, structure elucidation and its induction of apoptosis in human colon HT-29 tumor cell via the reactive oxygen species-mitochondrial dysfunction and MAPK activation.
Author: Wei, Anhua|Zhou, Daonian|Xiong, Chaomei|Cai, Yaling|Ruan, Jinlan
PMID: 21741427
Journal: Hered Cancer Clin Pract. 2011 Aug 6;9(1):5.
Title: Drug therapy for hereditary cancers.
Author: Imyanitov, Evgeny N|Moiseyenko, Vladimir M
PMID: 21819606
Journal: J Proteomics. 2011 Dec 21;75(2):384-97.
Title: Proteomic analysis of 1alpha,25-dihydroxyvitamin D3 action on human colon cancer cells reveals a link to splicing regulation.
Author: Cristobo, Ivan|Larriba, Maria Jesus|de los Rios, Vivian|Garcia, Francisco|Munoz, Alberto|Casal, J Ignacio
PMID: 21864731
Journal: J Nat Prod. 2011 Sep 23;74(9):1851-61.
Title: An unfractionated fucoidan from Ascophyllum nodosum: extraction, characterization, and apoptotic effects in vitro.
Author: Foley, Sarah A|Szegezdi, Eva|Mulloy, Barbara|Samali, Afshin|Tuohy, Maria G
PMID: 21875034
Journal: Biol Pharm Bull. 2011;34(10):1553-8.
Title: Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells.
Author: Khanal, Prem|Kang, Bong Seok|Yun, Hyo Jeong|Cho, Hae-Guk|Makarieva, Tatyana Nikolaevna|Choi, Hong Seok
PMID: 21963494
Journal: Anticancer Res. 2011 Nov;31(11):3799-807.
Title: Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Author: Sreevalsan, Sandeep|Joseph, Sonia|Jutooru, Indira|Chadalapaka, Gayathri|Safe, Stephen H
PMID: 22110202
Journal: PLoS One. 2011;6(12):e28862.
Title: Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
Author: Geng, Liyi|Huehls, Amelia M|Wagner, Jill M|Huntoon, Catherine J|Karnitz, Larry M
PMID: 22194930
Journal: Oncol Lett. 2011 Jul;2(4):643-647.
Title: Rapamycin synergizes with low-dose oxaliplatin in the HCT116 colon cancer cell line by inducing enhanced apoptosis.
Author: Lu, Xueying|Wei, Haibo|Zhang, Xiaojin|Zheng, Wenxin|Chang, Cheng|Gu, Jinyu
PMID: 22848242
Journal: Pathol Oncol Res. 2012 Apr;18(2):191-9.
Title: Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFkappa-B pathway.
Author: Fauzee, Nilufer Jasmine Selimah|Li, Qiaozhuan|Wang, Ya-Lan|Pan, Juan
PMID: 21713600
Journal: Dig Dis Sci. 2012 Feb;57(2):371-80.
Title: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells.
Author: Chung, Cho-Yun|Park, Young-Lan|Song, Young-A|Myung, Eun|Kim, Kyu-Yeol|Lee, Gi-Hoon|Ki, Ho-Seok|Park, Kang-Jin|Cho, Sung-Bum|Lee, Wan-Sik|Jung, Young-Do|Kim, Kyung-Keun|Joo, Young-Eun
PMID: 21901254
Journal: J Cell Mol Med. 2012 Aug;16(8):1878-88.
Title: Inhibition of JAK2/STAT3 signalling induces colorectal cancer cell apoptosis via mitochondrial pathway.
Author: Du, Wan|Hong, Jie|Wang, Ying-Chao|Zhang, Yan-Jie|Wang, Ping|Su, Wen-Yu|Lin, Yan-Wei|Lu, Rong|Zou, Wei-Ping|Xiong, Hua|Fang, Jing-Yuan
PMID: 22050790
Journal: Curr Cancer Drug Targets. 2012 May;12(4):329-38.
Title: Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.
Author: Soncini, D|Caffa, I|Patrone, F|Ballestrero, A|Nencioni, A
PMID: 22385509
Journal: Curr Cancer Drug Targets. 2012 May;12(4):356-71.
Title: DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.
Author: Solier, S|Zhang, Y-W|Ballestrero, A|Pommier, Y|Zoppoli, G
PMID: 22385513
Journal: Oncol Rep. 2012 Jun;27(6):2023-30.
Title: Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis.
Author: Lim, Soo-Jeong|Lee, Eunmyong|Lee, Eun-Hye|Kim, Soo-Yeon|Cha, Jun Hyung|Choi, Hwanho|Park, Wanseo|Choi, Hyeon Kyeom|Ko, Seong-Hee|Kim, So Hee
PMID: 22395735
Journal: Am J Cancer Res. 2012;2(2):168-77. Epub 2012 Feb 15.
Title: Tumor growth is suppressed in mice expressing a truncated XRCC1 protein.
Author: Pettan-Brewer, Christina|Morton, John|Cullen, Sarah|Enns, Linda|Kehrli, Keffy Rm|Sidorova, Julia|Goh, Jorming|Coil, Rebecca|Ladiges, Warren C
PMID: 22432057
Journal: Cell Physiol Biochem. 2012;29(3-4):361-72.
Title: RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway.
Author: Li, Qiaozhuan|Li, Ming|Wang, Ya-Lan|Fauzee, Nilufer Jasmine Selimah|Yang, Yi|Pan, Juan|Yang, Lian|Lazar, Alexander
PMID: 22508044
Journal: Radiat Oncol. 2012 Apr 23;7:62.
Title: The combination of olaparib and camptothecin for effective radiosensitization.
Author: Miura, Katsutoshi|Sakata, Koh-ichi|Someya, Masanori|Matsumoto, Yoshihisa|Matsumoto, Hideki|Takahashi, Akihisa|Hareyama, Masato
PMID: 22524618
Journal: J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):280-286.
Title: Down-regulation of p110beta expression increases chemosensitivity of colon cancer cell lines to oxaliplatin.
Author: Liu, Weicheng|Wang, Guihua|Cao, Xiaonian|Luo, Xuelai|Li, Zhaoming|Deng, Yu|Li, Xiaolan|Wang, Shijia|Liu, Mengfei|Hu, Junbo|Wang, Jing
PMID: 22528234
Journal: PLoS One. 2012;7(5):e36418.
Title: Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor.
Author: Wang, Lihong|Liu, Liping|Shi, Yan|Cao, Hanwei|Chaturvedi, Rupesh|Calcutt, M Wade|Hu, Tianhui|Ren, Xiubao|Wilson, Keith T|Polk, D Brent|Yan, Fang
PMID: 22574158
Journal: Eur J Pharmacol. 2012 Aug 5;688(1-3):14-21.
Title: The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells.
Author: Chidambara Murthy, Kotamballi N|Jayaprakasha, Guddadarangavvanahally K|Patil, Bhimanagouda S
PMID: 22617025
Journal: Toxicol Appl Pharmacol. 2012 Aug 1;262(3):293-300.
Title: SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine.
Author: Zhao, Cuirong|Yue, Bin|Liu, Huiping|Sun, Cuicui|Li, Wenbao|Qu, Xianjun
PMID: 22617428
Journal: Mol Cells. 2012 Jul;34(1):61-9.
Title: Protein kinase Calpha protects against multidrug resistance in human colon cancer cells.
Author: Lee, Se-Kyoung|Shehzad, Adeeb|Jung, Jae-Chang|Sonn, Jong-Kyung|Lee, Jae-Tae|Park, Jeen-Woo|Lee, Young-Sup
PMID: 22639047
Journal: J Surg Oncol. 2012 Nov;106(6):680-8.
Title: AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells.
Author: Yang, Weng-Lang|Perillo, William|Liou, Deanna|Marambaud, Philippe|Wang, Ping
PMID: 22674626
Journal: Toxicol In Vitro. 2012 Sep;26(6):775-82.
Title: Inhibition of GSK-3beta reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.
Author: Jendzelovsky, Rastislav|Koval, Jan|Mikes, Jaromir|Papcova, Zuzana|Plsikova, Jana|Fedorocko, Peter
PMID: 22683934
Journal: Toxicol In Vitro. 2012 Oct;26(7):1216-23.
Title: Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
Author: Kim, Jinhee|Jayaprakasha, Guddadarangavvanahally K|Vikram, Amit|Patil, Bhimanagouda S
PMID: 22728232
Journal: Oncol Lett. 2012 Feb;3(2):441-444.
Title: MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3'-deoxyadenosine) in vitro.
Author: Imesch, Patrick|Goerens, Anouk|Fink, Daniel|Fedier, Andre
PMID: 22740928
Journal: Curr Med Chem. 2012;19(23):3874-85.
Title: DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets.
Author: Alagoz, M|Gilbert, D C|El-Khamisy, S|Chalmers, A J
PMID: 22788763
Journal: Biol Pharm Bull. 2012;35(7):1054-63.
Title: (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation.
Author: Hong, Ji-Young|Boo, Hye-Jin|Kang, Jung-Il|Kim, Min-Kyoung|Yoo, Eun-Sook|Hyun, Jin-Won|Koh, Young-Sang|Kim, Gi Young|Maeng, Young Hee|Hyun, Chang Lim|Chang, Weon Young|Kim, Young Ho|Kim, Young Ree|Kang, Hee-Kyoung
PMID: 22791152
Journal: Eur J Pharm Sci. 2012 Sep 29;47(2):464-73.
Title: A novel steroidal saponin glycoside from Fagonia indica induces cell-selective apoptosis or necrosis in cancer cells.
Author: Waheed, Abdul|Barker, James|Barton, Stephen J|Owen, Caroline P|Ahmed, Sabbir|Carew, Mark A
PMID: 22800968
Journal: Neoplasma. 2012;59(6):676-84.
Title: Enhanced chemosensitivity to CPT-11 in colorectal carcinoma xenografts by small hairpin RNA interference targeting PLK1.
Author: Fan, P|Zhang, S|Tian, H|Yan, N|Dai, L|Zhang, X|Cheng, L|Li, C|Li, Y|Chen, X|Shi, G|Yang, Y|Wei, Y|Deng, H
PMID: 22862168
Journal: Pol J Pathol. 2012 Jun;63(2):87-92.
Title: Colorectal cancers differ in respect of PARP-1 protein expression.
Author: Sulzyc-Bielicka, Violetta|Domagala, Pawel|Hybiak, Jolanta|Majewicz-Broda, Anna|Safranow, Krzysztof|Domagala, Wenecjanusz
PMID: 22864776
Journal: Cancer Gene Ther. 2012 Oct;19(10):715-22.
Title: Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation.
Author: Pan, J|Fauzee, N J S|Wang, Y-l|Sheng, Y-T|Tang, Y|Wang, J-Q|Wu, W-q|Yan, J-x|Xu, J
PMID: 22918473
Journal: Oncol Rep. 2012 Nov;28(5):1719-26.
Title: Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells.
Author: Ren, Jie|Cheng, Hong|Xin, Wen Qun|Chen, Xin|Hu, Kun
PMID: 22948973
Journal: Clin Cancer Res. 2012 Nov 1;18(21):5878-87.
Title: Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas.
Author: Slyskova, Jana|Korenkova, Vlasta|Collins, Andrew R|Prochazka, Pavel|Vodickova, Ludmila|Svec, Jiri|Lipska, Ludmila|Levy, Miroslav|Schneiderova, Michaela|Liska, Vaclav|Holubec, Lubos|Kumar, Rajiv|Soucek, Pavel|Naccarati, Alessio|Vodicka, Pavel
PMID: 22966016
Journal: J Ethnopharmacol. 2012 Oct 11;143(3):914-9.
Title: Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
Author: Tsai, Yu-Ling|Chiu, Chien-Chih|Yi-Fu Chen, Jeff|Chan, Kung-Chi|Lin, Sheng-Dun
PMID: 22971663
Journal: Apoptosis. 2012 Dec;17(12):1300-15.
Title: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.
Author: Gandesiri, Muktheshwar|Chakilam, Saritha|Ivanovska, Jelena|Benderska, Natalya|Ocker, Matthias|Di Fazio, Pietro|Feoktistova, Maria|Gali-Muhtasib, Hala|Rave-Frank, Margret|Prante, Olaf|Christiansen, Hans|Leverkus, Martin|Hartmann, Arndt|Schneider-Stock, Reg
PMID: 23011180
Journal: Int J Oncol. 2012 Dec;41(6):2079-86.
Title: PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development.
Author: Tuncel, Handan|Tanaka, Shinji|Oka, Shiro|Nakai, Shiro|Fukutomi, Ryuichiro|Okamoto, Mayumi|Ota, Takahide|Kaneko, Hiroshi|Tatsuka, Masaaki|Shimamoto, Fumio
PMID: 23042038
Journal: Arch Pharm Res. 2012 Sep;35(9):1559-65.
Title: Cytotoxic caffeic acid derivatives from the rhizomes of Cimicifuga heracleifolia.
Author: Yim, Soon-Ho|Kim, Hyun Jung|Park, Si-Hwan|Kim, Jinmi|Williams, Darren R|Jung, Da-Woon|Lee, Ik-Soo
PMID: 23054712
Journal: Life Sci. 2012 Dec 17;91(25-26):1295-303.
Title: Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo.
Author: Liang, Lei|Wang, Xiao-Yan|Zhang, Xu-Hui|Ji, Bo|Yan, Hua-Cheng|Deng, Hong-Zhu|Wu, Xin-Rong
PMID: 23069582
Journal: Oncol Res. 2012;20(2-3):81-91.
Title: Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism.
Author: Mohapatra, Purusottam|Preet, Ranjan|Das, Dipon|Satapathy, Shakti Ranjan|Choudhuri, Tathagata|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 23193914
Journal: BMC Cancer. 2012 Dec 17;12:601.
Title: Up-regulated expression of l-caldesmon associated with malignancy of colorectal cancer.
Author: Kim, Kyung-Hee|Yeo, Seung-Gu|Kim, Won Ki|Kim, Dae Yong|Yeo, Hyun Yang|Hong, Jun Pyu|Chang, Hee Jin|Park, Ji Won|Kim, Sun Young|Kim, Byung Chang|Yoo, Byong Chul
PMID: 23241148
Journal: Int J Cancer. 2013 Feb 1;132(3):707-16.
Title: Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
Author: Kan, Winnie Lai Ting|Yin, Chun|Xu, Hong Xi|Xu, Gang|To, Kenneth Kin Wah|Cho, Chi Hin|Rudd, John Anthony|Lin, Ge
PMID: 22733377
Journal: Invest New Drugs. 2013 Apr;31(2):461-8.
Title: The PARP inhibitor ABT-888 synergizes irinotecan treatment of colon cancer cell lines.
Author: Davidson, David|Wang, Yunzhe|Aloyz, Raquel|Panasci, Lawrence
PMID: 23054213
Journal: Bioorg Med Chem Lett. 2013 Jan 1;23(1):158-62.
Title: Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines.
Author: Tung, Nguyen Huu|Uto, Takuhiro|Sakamoto, Ayana|Hayashida, Yuka|Hidaka, Yuuki|Morinaga, Osamu|Lhieochaiphant, Sorasak|Shoyama, Yukihiro
PMID: 23206866
Journal: Biochem Pharmacol. 2013 Apr 15;85(8):1057-65.
Title: Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.
Author: Morad, Samy A F|Madigan, James P|Levin, Jonathan C|Abdelmageed, Noha|Karimi, Ramin|Rosenberg, Daniel W|Kester, Mark|Shanmugavelandy, Sriram S|Cabot, Myles C
PMID: 23353700
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jan;16(1):84-8.
Title: [Influence of oxaliplatin combined with LCP on proliferation and apoptosis of colon cancer cell line HT29].
Author: Lu, Wei-qun|Wang, Feng|Liu, Hai-ying
PMID: 23355248
Journal: Anticancer Drugs. 2013 Apr;24(4):355-65.
Title: Induction of apoptosis and suppression of ERCC1 expression by the potent amonafide analogue 8-c in human colorectal carcinoma cells.
Author: Wang, Ziyuan|Liang, Xin|Cheng, Zhuoan|Xu, Yufang|Yin, Peihao|Zhu, Huirong|Li, Qi|Qian, Xuhong|Liu, Jianwen
PMID: 23426174
Journal: Med Oncol. 2013 Jun;30(2):505.
Title: Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a northeast Chinese population.
Author: Li, Ye|Li, Shuying|Wu, Zhiwei|Hu, Fulan|Zhu, Lin|Zhao, Xiaojuan|Cui, Binbin|Dong, Xinshu|Tian, Suli|Wang, Fan|Zhao, Yashuang
PMID: 23430444
Journal: PLoS One. 2013;8(2):e57218.
Title: Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
Author: Shakibaei, Mehdi|Mobasheri, Ali|Lueders, Cora|Busch, Franziska|Shayan, Paviz|Goel, Ajay
PMID: 23451189
Journal: PLoS One. 2013;8(2):e57871.
Title: ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability.
Author: Errami, Youssef|Brim, Hassan|Oumouna-Benachour, Karine|Oumouna, Mustapha|Naura, Amarjit S|Kim, Hogyoung|Ju, Jihang|Davis, Christian J|Kim, Jong G|Ashktorab, Hassan|Fallon, Kenneth|Xu, Ming|Zhang, Jianhua|Del Valle, Luis|Boulares, A Hamid
PMID: 23451280
Journal: Arch Pharm Res. 2013 Aug;36(8):1023-8.
Title: Methoxyphenylcipro induces antitumor activity in human cancer cells.
Author: Mhaidat, Nizar M|Qandil, Amjad M|Al-Balas, Qosay A|Hassan, Mohammad A|Jaradat, Saied A|Matalkah, Ahmad M|Thorne, Rick T
PMID: 23508743
Journal: Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):469-76.
Title: In vitro and in vivo enhancement of chemoradiation using the oral PARP inhibitor ABT-888 in colorectal cancer cells.
Author: Shelton, Joseph W|Waxweiler, Timothy V|Landry, Jerome|Gao, Huiying|Xu, Yanbo|Wang, Lanfang|El-Rayes, Bassel|Shu, Hui-Kuo G
PMID: 23540347
Journal: Mol Cell Biochem. 2013 Jul;379(1-2):171-80.
Title: Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFkappaB activity.
Author: Han, Peng|Luan, Ying|Liu, Yanlong|Yu, Zhiwei|Li, Jingwen|Sun, Zicheng|Chen, Gang|Cui, Binbin
PMID: 23559092
Journal: J Physiol Pharmacol. 2013 Feb;64(1):115-23.
Title: Evaluation of apoptotic activity of new condensed pyrazole derivatives.
Author: Toton, E|Ignatowicz, E|Bernard, M K|Kujawski, J|Rybczynska, M
PMID: 23568979
Journal: Cancer Chemother Pharmacol. 2013 Jul;72(1):117-25.
Title: MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.
Author: Tentori, Lucio|Muzi, Alessia|Dorio, Annalisa Susanna|Dolci, Susanna|Campolo, Federica|Vernole, Patrizia|Lacal, Pedro Miguel|Praz, Francoise|Graziani, Grazia
PMID: 23636450
Journal: Int J Mol Med. 2013 Jul;32(1):130-6.
Title: Inhibition of arginine ADP-ribosyltransferase 1 reduces the expression of poly(ADP-ribose) polymerase-1 in colon carcinoma.
Author: Tang, Yi|Wang, Ya-Lan|Yang, Lian|Xu, Jian-Xia|Xiong, Wei|Xiao, Ming|Li, Ming
PMID: 23652727
Journal: Int J Oncol. 2013 Jul;43(1):210-8.
Title: Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.
Author: Tentori, Lucio|Leonetti, Carlo|Muzi, Alessia|Dorio, Annalisa Susanna|Porru, Manuela|Dolci, Susanna|Campolo, Federica|Vernole, Patrizia|Lacal, Pedro Miguel|Praz, Francoise|Graziani, Grazia
PMID: 23653048
Journal: Clin Cancer Res. 2013 Jul 15;19(14):3820-31.
Title: Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy.
Author: Grassilli, Emanuela|Narloch, Robert|Federzoni, Elena|Ianzano, Leonarda|Pisano, Fabio|Giovannoni, Roberto|Romano, Gabriele|Masiero, Laura|Leone, Biagio Eugenio|Bonin, Serena|Donada, Marisa|Stanta, Giorgio|Helin, Kristian|Lavitrano, Marialuisa
PMID: 23729362
Journal: J Pharmacol Sci. 2013;122(2):153-7. Epub 2013 Jun 5.
Title: Influence of novel supramolecular substance, [2] rotaxane, on the caspase signaling pathway in melanoma and colon cancer cells in vitro.
Author: Hara, Kazuki|Beppu, Tatsuya|Kimura, Masahiko|Fujita, Yoshihiko|Takata, Toshikazu|Nishio, Kazuto|Ono, Nobufumi
PMID: 23739594
Journal: BMC Complement Altern Med. 2013 Jun 8;13:128.
Title: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
Author: Deng, Shan|Hu, Bing|An, Hong-Mei|Du, Qin|Xu, Ling|Shen, Ke-Ping|Shi, Xiu-Feng|Wei, Meng-Meng|Wu, Yang
PMID: 23758730
Journal: Ukr Biokhim Zh (1999). 2013 Mar-Apr;85(2):33-44.
Title: [Effect of free and polymer carrier encapsulated doxorubicin towards HCT116 cells of human colorectal carcinoma].
Author: Sen'kiv, Iu V|Heffeter, P|Riabtseva, A O|Boiko, N M|Mitina, N Ie|Zaichenko, O S|Berger, W|Stoika, R S
PMID: 23808308
Journal: Pharm Biol. 2013 Dec;51(12):1508-14.
Title: Cleome arabica leaf extract has anticancer properties in human cancer cells.
Author: Tigrine, Chafia|Bulzomi, Pamela|Leone, Stefano|Bouriche, Hamama|Kameli, Abdelkarim|Marino, Maria
PMID: 23862683
Journal: Life Sci. 2013 Sep 3;93(8):344-51.
Title: Dihydrotanshinone induces p53-independent but ROS-dependent apoptosis in colon cancer cells.
Author: Wang, L|Yeung, J H K|Hu, T|Lee, W Y|Lu, L|Zhang, L|Shen, J|Chan, R L Y|Wu, W K K|Cho, C H
PMID: 23871989
Journal: Eur J Pharmacol. 2013 Aug 15;714(1-3):379-87.
Title: PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.
Author: Gangemi, Giuseppina|Gazzerro, Patrizia|Fiore, Donatella|Proto, Maria Chiara|Butini, Stefania|Gemma, Sandra|Casagni, Alice|Laezza, Chiara|Vitale, Mario|Ligresti, Alessia|Di Marzo, Vincenzo|Zisterer, Daniela M|Nathwani, Seema|Clive Williams, D|Campiani, Giu
PMID: 23872382
Journal: J Agric Food Chem. 2013 Sep 11;61(36):8533-40.
Title: Inhibitory effects of different forms of tocopherols, tocopherol phosphates, and tocopherol quinones on growth of colon cancer cells.
Author: Dolfi, Sonia C|Yang, Zhihong|Lee, Mao-Jung|Guan, Fei|Hong, Jungil|Yang, Chung S
PMID: 23898832
Journal: Cancer Gene Ther. 2013 Sep;20(9):487-92.
Title: Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets.
Author: Yan, J|Li, M|Threadgill, M D|Wang, Y|Fu, W
PMID: 23949281
Journal: Apoptosis. 2013 Dec;18(12):1586-98.
Title: Multiple effects of the Na(+)/H (+) antiporter inhibitor HMA on cancer cells.
Author: Aredia, Francesca|Giansanti, Vincenzo|Mazzini, Giuliano|Savio, Monica|Ortiz, Luis Miguel Guaman|Jaadane, Imene|Zaffaroni, Nadia|Forlino, Antonella|Torriglia, Alicia|Scovassi, Anna Ivana
PMID: 23996609
Journal: PLoS One. 2013 Sep 2;8(9):e73262.
Title: Expression of Livin in colorectal cancer and its relationship to tumor cell behavior and prognosis.
Author: Myung, Dae-Seong|Park, Young-Lan|Chung, Cho-Yun|Park, Hyung-Chul|Kim, Jong-Sun|Cho, Sung-Bum|Lee, Wan-Sik|Lee, Kyung-Hwa|Lee, Jae-Hyuk|Joo, Young-Eun
PMID: 24023847
Journal: Oncol Rep. 2013 Dec;30(6):2647-52.
Title: Antitumor effect of 1, 8-cineole against colon cancer.
Author: Murata, Soichiro|Shiragami, Risa|Kosugi, Chihiro|Tezuka, Tohru|Yamazaki, Masato|Hirano, Atsushi|Yoshimura, Yukino|Suzuki, Masato|Shuto, Kiyohiko|Ohkohchi, Nobuhiro|Koda, Keiji
PMID: 24085263
Journal: Toxicol In Vitro. 2013 Dec;27(8):2256-63.
Title: Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs.
Author: Dinicola, Simona|Morini, Veronica|Coluccia, Pierpaolo|Proietti, Sara|D'Anselmi, Fabrizio|Pasqualato, Alessia|Masiello, Maria Grazia|Palombo, Alessandro|De Toma, Giorgio|Bizzarri, Mariano|Cucina, Alessandra
PMID: 24095863
Journal: J Drug Target. 2013 Nov 13.
Title: Characterization of oleanolic acid derivative for colon cancer targeting with positron emission tomography.
Author: Kim, Sung-Min|Jeong, Il Ha|Yim, Min Su|Chae, Min Kyung|Kim, Hak Nam|Kim, Dong Kue|Kang, Choong Mo|Choe, Yearn Seong|Lee, Chulhyun|Ryu, Eun Kyoung
PMID: 24219340
Journal: Iran J Pharm Res. 2013 Spring;12(2):453-60.
Title: 5-Fluorouracil Induce the Expression of TLR4 on HCT116 Colorectal Cancer Cell Line Expressing Different Variants of TLR4.
Author: Davoodi, Homa|Hashemi, Seyed Reza|Seow, Heng Fong
PMID: 24250621
Journal: J Med Chem. 2013 Dec 27;56(24):10003-15.
Title: Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Author: Hua, Zihao|Bregman, Howard|Buchanan, John L|Chakka, Nagasree|Guzman-Perez, Angel|Gunaydin, Hakan|Huang, Xin|Gu, Yan|Berry, Virginia|Liu, Jingzhou|Teffera, Yohannes|Huang, Liyue|Egge, Bryan|Emkey, Renee|Mullady, Erin L|Schneider, Steve|Andrews, Paul S|Acqu
PMID: 24294969
Journal: ACS Med Chem Lett. 2013 Oct 21;4(12):1218-23.
Title: Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors.
Author: Huang, Hongbing|Guzman-Perez, Angel|Acquaviva, Lisa|Berry, Virginia|Bregman, Howard|Dovey, Jennifer|Gunaydin, Hakan|Huang, Xin|Huang, Liyue|Saffran, Doug|Serafino, Randy|Schneider, Steve|Wilson, Cindy|DiMauro, Erin F
PMID: 24900633
Journal: Int J Cancer. 2014 Jan 15;134(2):376-83.
Title: 8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients.
Author: Dziaman, Tomasz|Banaszkiewicz, Zbigniew|Roszkowski, Krzysztof|Gackowski, Daniel|Wisniewska, Ewa|Rozalski, Rafal|Foksinski, Marek|Siomek, Agnieszka|Speina, Elzbieta|Winczura, Alicja|Marszalek, Andrzej|Tudek, Barbara|Olinski, Ryszard
PMID: 23832862
Journal: Tumour Biol. 2014 Mar;35(3):1715-25.
Title: Two DNA repair gene polymorphisms on the risk of gastrointestinal cancers: a meta-analysis.
Author: Hu, Yue|Zhou, Min|Li, Kang|Zhang, Kai|Kong, Xiangquan|Zheng, Yamei|Li, Jianxu|Liu, Li
PMID: 24203816
Journal: Cancer Lett. 2014 Feb 28;343(2):217-23.
Title: Poly (ADP-ribose) polymerase inhibitor LT-626: Sensitivity correlates with MRE11 mutations and synergizes with platinums and irinotecan in colorectal cancer cells.
Author: McPherson, Lisa A|Shen, Yuqiao|Ford, James M
PMID: 24215868
Journal: Curr Cancer Drug Targets. 2014;14(2):156-66.
Title: Anticancer effect of a curcumin derivative B63: ROS production and mitochondrial dysfunction.
Author: Zheng, Adi|Li, Hao|Wang, Xun|Feng, Zhihui|Xu, Jie|Cao, Ke|Zhou, Bo|Wu, Jing|Liu, Jiankang
PMID: 24274397
Journal: Cell Biol Int. 2014 Mar;38(3):343-54.
Title: DMPPQA, a novel angiogenesis inhibitor, induces apoptosis in human colon cancer HCT-116 cells and HUVECs.
Author: Ren, Jie|Jiang, Hefei|Zhao, Juan|Xin, Wenqun|Xu, Yuanyuan|Chen, Xin|Hu, Kun
PMID: 24293112
Journal: Eur J Cancer. 2014 Feb;50(3):663-74.
Title: Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas.
Author: Picault, Francois-Xavier|Chaves-Almagro, Carline|Projetti, Fabrice|Prats, Herve|Masri, Bernard|Audigier, Yves
PMID: 24316062
Journal: Biochem Biophys Res Commun. 2014 Jan 17;443(3):852-7.
Title: AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Author: Igarashi, Maki|Hippo, Yoshitaka|Ochiai, Masako|Fukuda, Hirokazu|Nakagama, Hitoshi
PMID: 24342614
Journal: PLoS One. 2014 Jan 8;9(1):e84627.
Title: Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-kappaB signaling in colorectal cancer.
Author: Kansal, Shevali|Bhatnagar, Archana|Agnihotri, Navneet
PMID: 24416253
Journal: Acta Pharmacol Sin. 2014 Mar;35(3):394-400.
Title: OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
Author: Arafa, El-shaimaa A|Abdelazeem, Ahmed H|Arab, Hany H|Omar, Hany A
PMID: 24464048
Journal: Int J Mol Med. 2014 Apr;33(4):943-9.
Title: Corosolic acid induces apoptotic cell death in HCT116 human colon cancer cells through a caspase-dependent pathway.
Author: Sung, Bokyung|Kang, Yong Jung|Kim, Dong Hwan|Hwang, Seong Yeon|Lee, Yujin|Kim, Minjeong|Yoon, Jeong-Hyun|Kim, Cheol Min|Chung, Hae Young|Kim, Nam Deuk
PMID: 24481288
Journal: Int J Oncol. 2014 Apr;44(4):1309-15.
Title: Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
Author: Park, Ki-Woong|Kundu, Juthika|Chae, In-Gyeong|Kim, Do-Hee|Yu, Mi-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24481553
Journal: Mol Cancer Ther. 2014 May;13(5):1170-80.
Title: The use of Olaparib (AZD2281) potentiates SN-38 cytotoxicity in colon cancer cells by indirect inhibition of Rad51-mediated repair of DNA double-strand breaks.
Author: Tahara, Makiko|Inoue, Takeshi|Sato, Futoshi|Miyakura, Yasuyuki|Horie, Hisanaga|Yasuda, Yoshikazu|Fujii, Hirofumi|Kotake, Kenjiro|Sugano, Kokichi
PMID: 24577941
Journal: Int J Oncol. 2014 May;44(5):1599-606.
Title: Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells.
Author: Lee, Yujin|Sung, Bokyung|Kang, Yong Jung|Kim, Dong Hwan|Jang, Jung-Yoon|Hwang, Seong Yeon|Kim, Minjung|Lim, Hyun Sook|Yoon, Jeong-Hyun|Chung, Hae Young|Kim, Nam Deuk
PMID: 24626522
Journal: Oncol Rep. 2014 May;31(5):2335-43.
Title: Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Author: Kuang, Jing|Wang, Ya-Lan|Xiao, Ming|Tang, Yi|Chen, Wen-Wen|Song, Guang-Lin|Yang, Xi|Li, Ming
PMID: 24676941
Journal: Am J Chin Med. 2014;42(2):465-83.
Title: Flavonoids identified from Korean Scutellaria baicalensis induce apoptosis by ROS generation and caspase activation on human fibrosarcoma cells.
Author: Zhang, Jue|Park, Hyeon-Soo|Kim, Jin-A|Hong, Gyeong-Eun|Nagappan, Arulkumar|Park, Kwang-Il|Kim, Gon-Sup
PMID: 24707875
Journal: Int J Oncol. 2014 Jun;44(6):2077-84.
Title: HIF-1alpha activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Author: Nishimoto, Arata|Kugimiya, Naruji|Hosoyama, Tohru|Enoki, Tadahiko|Li, Tao-Sheng|Hamano, Kimikazu
PMID: 24718784
Journal: Oncotarget. 2014 May 15;5(9):2807-19.
Title: Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan.
Author: Maitra, Radhashree|Seetharam, Raviraja|Tesfa, Lydia|Augustine, Titto A|Klampfer, Lidija|Coffey, Matthew C|Mariadason, John M|Goel, Sanjay
PMID: 24798549
Journal: Chem Biol Interact. 2014 Jul 25;218:42-9.
Title: Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells.
Author: Lin, Mei-Hsiang|Cheng, Chia-Hsiung|Chen, Ku-Chung|Lee, Wai-Theng|Wang, Yen-Fang|Xiao, Cai-Qin|Lin, Cheng-Wei
PMID: 24812029
Journal: Tumour Biol. 2014 Aug;35(8):7877-85.
Title: Limoniastrum guyonianum aqueous gall extract induces apoptosis in colorectal cancer cells by inhibiting calpain activity.
Author: Krifa, Mounira|Pizzi, Antonio|Mousli, Marc|Chekir-Ghedira, Leila|Leloup, Ludovic|Ghedira, Kamel
PMID: 24828012
Journal: PLoS One. 2014 May 14;9(5):e92786.
Title: The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells.
Author: Chung, Tae-Wook|Choi, Hee-Jung|Kim, Seok-Jo|Kwak, Choong-Hwan|Song, Kwon-Ho|Jin, Un-Ho|Chang, Young-Chae|Chang, Hyeun Wook|Lee, Young-Choon|Ha, Ki-Tae|Kim, Cheorl-Ho
PMID: 24829158
Journal: J Cancer. 2014 Apr 25;5(6):406-16.
Title: Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms.
Author: Doudican, Nicole A|Mazumder, Amitabha|Kapoor, Shweta|Sultana, Zeba|Kumar, Ansu|Talawdekar, Anay|Basu, Kabya|Agrawal, Ashish|Aggarwal, Aditi|Shetty, Krithika|Singh, Neeraj K|Kumar, Chandan|Tyagi, Anuj|Singh, Neeraj Kumar|Darlybai, Janitha C|Abbasi, Taher|V
PMID: 24847381
Journal: Int J Mol Sci. 2014 May 22;15(5):9103-16.
Title: Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Author: Liang, Zengenni|Yi, Youjin|Guo, Yutong|Wang, Rencai|Hu, Qiulong|Xiong, Xingyao
PMID: 24857920
Journal: Asian Pac J Cancer Prev. 2014;15(8):3667-73.
Title: Novel mutations of the PARP-1 gene associated with colorectal cancer in the Saudi population.
Author: Alshammari, Atika Hazzaa|Shalaby, Manal Aly|Alanazi, Mohammad Saud|Saeed, Hesham Mahmoud
PMID: 24870775
Journal: Mol Cancer. 2014 May 26;13:124.
Title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.
Author: Zhang, Lijing|Dong, Yujuan|Zhu, Nana|Tsoi, Ho|Zhao, Zengren|Wu, Chung Wah|Wang, Kunning|Zheng, Shu|Ng, Simon Sm|Chan, Francis Kl|Sung, Joseph Jy|Yu, Jun
PMID: 24885920
Journal: Oncol Rep. 2014 Aug;32(2):821-8.
Title: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author: Kundu, Juthika|Choi, Bu Young|Jeong, Chul-Ho|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24890449
Journal: J Cell Biochem. 2014 Nov;115(11):1888-99.
Title: Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells.
Author: Lai, Ying-Jiun|Lin, Chien-I|Wang, Chia-Lin|Chao, Jui-I
PMID: 24905183
Journal: Chem Biol Interact. 2014 Sep 5;220:41-50.
Title: The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer.
Author: Huang, Yu-Tin|Lin, Chien-I|Chien, Pei-Hsuan|Tang, Tsai-Tai|Lin, Johnson|Chao, Jui-I
PMID: 24931875
Journal: Oncol Lett. 2014 Jun;7(6):1992-1996.
Title: Sorbitol induces apoptosis of human colorectal cancer cells via p38 MAPK signal transduction.
Author: Lu, Xue|Li, Chun|Wang, Yong-Kun|Jiang, Kun|Gai, Xiao-Dong
PMID: 24932277
Journal: PLoS One. 2014 Jun 24;9(6):e99729.
Title: Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine.
Author: Chien, Chih-Chiang|Wu, Ming-Shun|Shen, Shing-Chuan|Ko, Ching-Huai|Chen, Chih-Hung|Yang, Ling-Ling|Chen, Yen-Chou
PMID: 24959718
Journal: PLoS One. 2014 Jul 3;9(7):e101303.
Title: Investigating migration inhibition and apoptotic effects of Fomitopsis pinicola chloroform extract on human colorectal cancer SW-480 cells.
Author: Wang, Yaqin|Cheng, Xiaoxia|Wang, Pan|Wang, Lu|Fan, Jianping|Wang, Xiaobing|Liu, Quanhong
PMID: 24992193
Journal: Br J Cancer. 2014 Sep 23;111(7):1319-26.
Title: Preferential potentiation of topoisomerase I poison cytotoxicity by PARP inhibition in S phase.
Author: Znojek, P|Willmore, E|Curtin, N J
PMID: 25003660
Journal: Tumour Biol. 2014 Oct;35(10):9967-75.
Title: Benzylidenetetralones, cyclic chalcone analogues, induce cell cycle arrest and apoptosis in HCT116 colorectal cancer cells.
Author: Drutovic, David|Chripkova, Martina|Pilatova, Martina|Kruzliak, Peter|Perjesi, Pal|Sarissky, Marek|Lupi, Monica|Damia, Giovanna|Broggini, Massimo|Mojzis, Jan
PMID: 25008568
Journal: Oncol Lett. 2014 Sep;8(3):1222-1228.
Title: XRCC2 rs3218536 polymorphism decreases the sensitivity of colorectal cancer cells to poly(ADP-ribose) polymerase 1 inhibitor.
Author: Xu, Kaiwu|Song, Xinming|Chen, Zhihui|Qin, Changjiang|He, Yulong
PMID: 25120693
Journal: PLoS One. 2014 Aug 19;9(8):e105405.
Title: Combination effect of epigenetic regulation and ionizing radiation in colorectal cancer cells.
Author: Kim, Joong-Gook|Bae, Jin-Han|Kim, Jin-Ah|Heo, Kyu|Yang, Kwangmo|Yi, Joo Mi
PMID: 25136811
Journal: Cancer Prev Res (Phila). 2014 Nov;7(11):1138-48.
Title: Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer.
Author: Vasudevan, Anita|Yu, Yingjie|Banerjee, Sanjeev|Woods, James|Farhana, Lulu|Rajendra, Sindhu G|Patel, Aamil|Dyson, Gregory|Levi, Edi|Maddipati, Krishna Rao|Majumdar, Adhip P N|Nangia-Makker, Pratima
PMID: 25193342
Journal: J Hematol Oncol. 2014 Sep 9;7:56.
Title: Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes.
Author: Edwards, Shanique K E|Baron, Jacqueline|Moore, Carissa R|Liu, Yan|Perlman, David H|Hart, Ronald P|Xie, Ping
PMID: 25200342
Journal: Nutr Cancer. 2014;66(7):1220-7.
Title: Luteolin induces apoptosis in BE colorectal cancer cells by downregulating calpain, UHRF1, and DNMT1 expressions.
Author: Krifa, Mounira|Leloup, Ludovic|Ghedira, Kamel|Mousli, Marc|Chekir-Ghedira, Leila
PMID: 25207720
Journal: ScientificWorldJournal. 2014;2014:703804.
Title: Myotubularin-related phosphatase 3 promotes growth of colorectal cancer cells.
Author: Zheng, Bo'an|Yu, Xiaojun|Chai, Rui
PMID: 25215329
Journal: Int J Mol Sci. 2014 Sep 29;15(10):17333-43.
Title: Effect of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in patients with colorectal cancer.
Author: Santos, Juliana C|Funck, Alexandre|Silva-Fernandes, Isabelle J L|Rabenhorst, Silvia H B|Martinez, Carlos A R|Ribeiro, Marcelo L
PMID: 25268610
Journal: Oncogenesis. 2014 Oct 13;3:e121.
Title: MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death.
Author: Oka, S|Leon, J|Tsuchimoto, D|Sakumi, K|Nakabeppu, Y
PMID: 25310643
Journal: Nutr Cancer. 2014;66(8):1394-405.
Title: Pro-apoptotic activities of polyphenolics from acai (Euterpe oleracea Martius) in human SW-480 colon cancer cells.
Author: Dias, Manoela Maciel dos Santos|Noratto, Giuliana|Martino, Hercia Stampini Duarte|Arbizu, Shirley|Peluzio, Maria do Carmo Gouveia|Talcott, Stephen|Ramos, Afonso Mota|Mertens-Talcott, Susanne U
PMID: 25329001
Journal: BMC Complement Altern Med. 2014 Oct 24;14:412.
Title: Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
Author: Liu, Bao-Xin-Zi|Zhou, Jin-Yong|Li, Yu|Zou, Xi|Wu, Jian|Gu, Jun-Fei|Yuan, Jia-Rui|Zhao, Bing-Jie|Feng, Liang|Jia, Xiao-Bin|Wang, Rui-Ping
PMID: 25342273
Journal: Biosci Rep. 2014 Dec 12;34(6):e00161.
Title: Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells.
Author: Yu, Xiaojun|Zheng, Bo'an|Chai, Rui
PMID: 25370813
Journal: BMC Cancer. 2014 Dec 15;14:949.
Title: CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha-induced apoptosis by tumor-associated macrophages.
Author: Kee, Ji-Ye|Ito, Aya|Hojo, Shozo|Hashimoto, Isaya|Igarashi, Yoshiko|Tsuneyama, Koichi|Tsukada, Kazuhiro|Irimura, Tatsuro|Shibahara, Naotoshi|Takasaki, Ichiro|Inujima, Akiko|Nakayama, Takashi|Yoshie, Osamu|Sakurai, Hiroaki|Saiki, Ikuo|Koizumi, Keiichi
PMID: 25495942
Journal: Medicine (Baltimore). 2014 Dec;93(28):e294.
Title: XRCC2 promotes colorectal cancer cell growth, regulates cell cycle progression, and apoptosis.
Author: Xu, Kaiwu|Song, Xinming|Chen, Zhihui|Qin, Changjiang|He, Yulong|Zhan, Wenhua
PMID: 25526472
Journal: PLoS One. 2014 Dec 19;9(12):e115558.
Title: PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1.
Author: Dziaman, Tomasz|Ludwiczak, Hubert|Ciesla, Jaroslaw M|Banaszkiewicz, Zbigniew|Winczura, Alicja|Chmielarczyk, Mateusz|Wisniewska, Ewa|Marszalek, Andrzej|Tudek, Barbara|Olinski, Ryszard
PMID: 25526641
Journal: Mol Pharm. 2015 Jan 5;12(1):287-97.
Title: Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.
Author: Peterson, Erica J|Menon, Vijay R|Gatti, Laura|Kipping, Ralph|Dewasinghe, Dilhara|Perego, Paola|Povirk, Lawrence F|Farrell, Nicholas P
PMID: 25407898
Journal: Phytother Res. 2015 Mar;29(3):357-65.
Title: Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis.
Author: Guo, Li-da|Shen, Yong-qing|Zhao, Xiao-han|Guo, Li-jian|Yu, Zhi-jun|Wang, Duo|Liu, Li-meng|Liu, Jing-ze
PMID: 25418925
Journal: Oncotarget. 2015 Jan 1;6(1):355-67.
Title: PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5-FU based chemotherapy.
Author: Chen, Jian|Lu, Huijun|Yan, Dongwang|Cui, Feifei|Wang, Xiaoliang|Yu, Fudong|Xue, Yingming|Feng, Xiaodong|Wang, Jingtao|Wang, Xiao|Jiang, Tao|Zhang, Meng|Zhao, Senlin|Yu, Yang|Tang, Huamei|Peng, Zhihai
PMID: 25426562
Journal: Eur J Med Chem. 2015 Jan 7;89:851-62.
Title: Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents.
Author: Bandyopadhyay, Debasish|Sanchez, Jorge L|Guerrero, Adrian M|Chang, Fang-Mei|Granados, Jose C|Short, John D|Banik, Bimal K
PMID: 25462285
Journal: J Agric Food Chem. 2015 Jan 14;63(1):150-9.
Title: Water stress proteins from Nostoc commune Vauch. exhibit anti-colon cancer activities in vitro and in vivo.
Author: Guo, Songjia|Shan, Shuhua|Jin, Xiaoting|Li, Zongwei|Li, Zhuoyu|Zhao, Liangqi|An, Quan|Zhang, Wei
PMID: 25524246
Journal: Arch Toxicol. 2015 Oct;89(10):1829-46.
Title: Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil.
Author: Dorsam, Bastian|Goder, Anja|Seiwert, Nina|Kaina, Bernd|Fahrer, Jorg
PMID: 25526924
Journal: Tumour Biol. 2015 May;36(5):3447-55.
Title: The small-molecule compound BM-1197 inhibits the antiapoptotic regulators Bcl-2/Bcl-xL and triggers apoptotic cell death in human colorectal cancer cells.
Author: Ye, Lijun|Yuan, Gang|Xu, Fei|Sun, Yueli|Chen, Ziyan|Chen, Miaohong|Li, Tianxiao|Sun, Pingping|Li, Shuxia|Sun, Jian
PMID: 25542230
Journal: Oncotarget. 2015 Mar 10;6(7):4745-56.
Title: The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells.
Author: Wei, Ning|Chu, Edward|Wu, Shao-yu|Wipf, Peter|Schmitz, John C
PMID: 25544765
Journal: Anticancer Res. 2015 Jan;35(1):229-37.
Title: Discovery of PAT-1102, a novel, potent and orally active histone deacetylase inhibitor with antitumor activity in cancer mouse models.
Author: Hiriyan, Jagadheshan|Shivarudraiah, Prasad|Gavara, Govindarajulu|Annamalai, Pazhanimuthu|Natesan, Selvakumar|Sambasivam, Ganesh|Sukumaran, Sunil K
PMID: 25550555
Journal: Gene. 2015 Apr 15;560(2):237-44.
Title: Lentiviral DDX46 knockdown inhibits growth and induces apoptosis in human colorectal cancer cells.
Author: Li, Ming|Ma, Yanchao|Huang, Pei|Du, Aonan|Yang, Xiaodong|Zhang, Shuyu|Xing, Chungen|Liu, Fenju|Cao, Jianping
PMID: 25680556
Journal: Cancer Cell Int. 2015 Feb 4;15(1):14.
Title: Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status.
Author: Genther Williams, Sybil M|Kuznicki, Apryle M|Andrade, Paula|Dolinski, Brian M|Elbi, Cem|O'Hagan, Ronan C|Toniatti, Carlo
PMID: 25685067
Journal: Int J Mol Med. 2015 May;35(5):1317-22.
Title: Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways.
Author: Zheng, Bo'an|Chai, Rui|Yu, Xiaojun
PMID: 25738796
Journal: Biomol Ther (Seoul). 2015 Mar;23(2):134-40.
Title: ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells.
Author: Kim, Kui-Jin|Lee, Jihye|Park, Yeonhwa|Lee, Seong-Ho
PMID: 25767681
Journal: ChemMedChem. 2015 May;10(5):827-35.
Title: Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells.
Author: Jun, Kyu-Yeon|Park, So-Eun|Liang, Jing Lu|Jahng, Yurngdong|Kwon, Youngjoo
PMID: 25809558
Journal: Biochem Biophys Res Commun. 2015 May 8;460(3):759-65.
Title: Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells.
Author: Yu, Shunji|Hou, Daisen|Chen, Ping|Zhang, Qi|Lv, Bin|Ma, Yunfang|Liu, Fuchen|Liu, Hui|Song, Evelyn J|Yang, Dongqin|Liu, Jie
PMID: 25817730
Journal: Acta Pharmacol Sin. 2015 Apr;36(4):517-27.
Title: Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
Author: Ma, Yi-ming|Han, Wei|Li, Jia|Hu, Li-hong|Zhou, Yu-bo
PMID: 25832431
Journal: Cell Physiol Biochem. 2015;35(5):1821-30.
Title: Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
Author: Yun, Miyong|Lee, Duckgue|Park, Moon-Nyeo|Kim, Eun-Ok|Sohn, Eun Jung|Kwon, Byung-Mog|Kim, Sung-Hoon
PMID: 25833196
Journal: Int J Mol Sci. 2015 Apr 3;16(4):7577-86.
Title: Poly-gamma-glutamic acid induces apoptosis via reduction of COX-2 expression in TPA-induced HT-29 human colorectal cancer cells.
Author: Shin, Eun Ju|Sung, Mi Jeong|Park, Jae Ho|Yang, Hye Jeong|Kim, Myung Sunny|Hur, Haeng Jeon|Hwang, Jin-Taek
PMID: 25854428
Journal: J Ethnopharmacol. 2015 Jun 20;168:291-304.
Title: Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells.
Author: Chan, Chim Kei|Supriady, Hadi|Goh, Bey Hing|Kadir, Habsah Abdul
PMID: 25861953
Journal: J Nanobiotechnology. 2015 Mar 3;13:18.
Title: Biocompatible iota-carrageenan-gamma-maghemite nanocomposite for biomedical applications - synthesis, characterization and in vitro anticancer efficacy.
Author: Raman, Maya|Devi, Viswambari|Doble, Mukesh
PMID: 25890231
Journal: Food Funct. 2015 May;6(5):1675-83.
Title: Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells.
Author: Cho, Hyunnho|Jung, Hana|Lee, Heejae|Yi, Hae Chang|Kwak, Ho-kyung|Hwang, Keum Taek
PMID: 25906041
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Apr;35(4):511-5.
Title: [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells].
Author: Liu, Jin-Kun|Hao, Ya-Juan|Huang, Jia-Wei|Li, Xin|Cai, Hong-Bing|Peng, Kang
PMID: 25907934
Journal: Int J Nanomedicine. 2015 Apr 8;10:2823-46.
Title: Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene.
Author: Huang, Rwei-Fen S|Wei, Yi-Jun|Inbaraj, Baskaran Stephen|Chen, Bing-Huei
PMID: 25914533
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Apr;18(4):370-5.
Title: [Co-inhibition effect of 17-DMAG and oxaliplatin on proliferation and invasion of colorectal cancer cells].
Author: Zhou, Jianping|Wang, Weimin|Deng, Jianliang|Zhou, Yan|Wu, Lulu|Guo, Zhiyuan|Shi, Jianneng|Shi, Jun|Zhou, Sujun|Xu, Zekuan
PMID: 25940182
Journal: Toxicol In Vitro. 2015 Aug;29(5):1156-65.
Title: Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis.
Author: Demoulin, Benjamin|Hermant, Maryse|Castrogiovanni, Cedric|Staudt, Catherine|Dumont, Patrick
PMID: 25952326
Journal: Am J Cancer Res. 2015 Jan 15;5(2):498-513. eCollection 2015.
Title: ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma.
Author: Tang, Yi|Li, Ming|Wang, Ya-Lan|Threadgill, Michael D|Xiao, Ming|Mou, Chun-Feng|Song, Guang-Lin|Kuang, Jing|Yang, Xi|Yang, Li|Gao, Xing-Jie|Wang, Ya-Ping|Meng, Yun-Peng
PMID: 25973293
Journal: BMC Cancer. 2015 May 16;15:411.
Title: The glutamate transport inhibitor DL-Threo-beta-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.
Author: Pedraz-Cuesta, Elena|Christensen, Sandra|Jensen, Anders A|Jensen, Niels Frank|Bunch, Lennart|Romer, Maria Unni|Brunner, Nils|Stenvang, Jan|Pedersen, Stine Falsig
PMID: 25981639
Journal: Int J Oncol. 2015 Aug;47(2):563-72.
Title: MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells.
Author: Choi, Pyoung Rak|Kang, Yong Jung|Sung, Bokyung|Kim, Jae Hyun|Moon, Hyung Ryong|Chung, Hae Young|Kim, Sung Eun|Park, Moo In|Park, Seun Ja|Kim, Nam Deuk
PMID: 26043797
Journal: Dalton Trans. 2015 Jul 14;44(26):11911-8.
Title: Exploring the potential of gold(III) cyclometallated compounds as cytotoxic agents: variations on the C^N theme.
Author: Bertrand, B|Spreckelmeyer, S|Bodio, E|Cocco, F|Picquet, M|Richard, P|Le Gendre, P|Orvig, C|Cinellu, M A|Casini, A
PMID: 26060937
Journal: Am J Chin Med. 2015;43(4):757-67.
Title: Antiproliferative and Pro-Apoptotic Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica in Human Leukemia Cell Lines.
Author: Uto, Takuhiro|Tung, Nguyen Huu|Appiah-Opong, Regina|Aning, Abigail|Morinaga, Osamu|Edoh, Dominic|Nyarko, Alexander K|Shoyama, Yukihiro
PMID: 26119959
Journal: Int J Mol Sci. 2015 Jun 29;16(7):14655-68.
Title: Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.
Author: Dong, Liwei|Yu, Debin|Wu, Nuoting|Wang, Hongge|Niu, Jiajing|Wang, Ye|Zou, Zhihua
PMID: 26132569
Journal: Lasers Med Sci. 2015 Sep;30(7):1967-75.
Title: Targeted inhibition of p38MAPK-enhanced autophagy in SW620 cells resistant to photodynamic therapy-induced apoptosis.
Author: Xue, Qin|Wang, Pan|Wang, Xiaobing|Zhang, Kun|Liu, Quanhong
PMID: 26254783
Journal: Front Pharmacol. 2015 Jul 22;6:147.
Title: Simultaneous inhibition of ATR and PARP sensitizes colon cancer cell lines to irinotecan.
Author: Abu-Sanad, Atlal|Wang, Yunzhe|Hasheminasab, Fatemeh|Panasci, Justin|Noe, Alycia|Rosca, Lorena|Davidson, David|Amrein, Lilian|Sharif-Askari, Bahram|Aloyz, Raquel|Panasci, Lawrence
PMID: 26257651
Journal: Int J Mol Sci. 2015 Aug 20;16(8):19851-67.
Title: Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway.
Author: Wang, Juan|Huang, Fengxiang|Bai, Zhun|Chi, Bixia|Wu, Jiacai|Chen, Xu
PMID: 26307972
Journal: Colloids Surf B Biointerfaces. 2015 Nov 1;135:793-801.
Title: Novel self-micellizing anticancer lipid nanoparticles induce cell death of colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Baskaran, Rengarajan|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Oh, Seung Hyun|Kyu Yoo, Bong|Kim, Hwan Mook
PMID: 26342325
Journal: PLoS One. 2015 Sep 14;10(9):e0137888.
Title: Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation.
Author: Kong, Lulu|Wang, Xiaobing|Zhang, Kun|Yuan, Wenjuan|Yang, Qiwen|Fan, Jianping|Wang, Pan|Liu, Quanhong
PMID: 26368019
Journal: EXCLI J. 2015 Feb 24;14:294-306.
Title: A sulfated polysaccharide of Ecklonia cava inhibits the growth of colon cancer cells by inducing apoptosis.
Author: Ahn, Ginnae|Lee, WonWon|Kim, Kil-Nam|Lee, Ji-Hyeok|Heo, Soo-Jin|Kang, Nalae|Lee, Seung-Hong|Ahn, Chang-Bum|Jeon, You-Jin
PMID: 26417363
Journal: Oncotarget. 2015 Dec 1;6(38):41307-23.
Title: E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.
Author: McGonigle, Sharon|Chen, Zhihong|Wu, Jiayi|Chang, Paul|Kolber-Simonds, Donna|Ackermann, Karen|Twine, Natalie C|Shie, Jue-Lon|Miu, Jingzang Tao|Huang, Kuan-Chun|Moniz, George A|Nomoto, Kenichi
PMID: 26513298
Journal: Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):1.
Title: Editorial.
Author: Farooqi, A A|Ismail, M
PMID: 26520390
Journal: Onco Targets Ther. 2015 Oct 20;8:3047-54.
Title: Combined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and gamma-H2AX foci formation in colorectal cancer.
Author: Xu, Kaiwu|Chen, Zhihui|Cui, Yi|Qin, Changjiang|He, Yulong|Song, Xinming
PMID: 26543375
Journal: Yao Xue Xue Bao. 2015 Jul;50(7):854-60.
Title: [The anti-tumor activity and molecular mechanisms of an Aurora kinase inhibitor ZLJ213 in suppressing colon cancer growth].
Author: Zhou, Wan-qi|Zhang, Li-jing|Yang, Han-ze|Feng, Zhi-qiang|Li, Yan
PMID: 26552147
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: Acta Pharmacol Sin. 2015 Dec;36(12):1514-9.
Title: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway.
Author: Su, Li-ya|Shi, Ying-xu|Yan, Mei-rong|Xi, Yaguang|Su, Xiu-lan
PMID: 26592508
Journal: Am J Cancer Res. 2015 Oct 15;5(11):3311-24. eCollection 2015.
Title: Sildenafil inhibits the growth of human colorectal cancer in vitro and in vivo.
Author: Mei, Xiao-Long|Yang, Yang|Zhang, Yao-Jun|Li, Yong|Zhao, Jin-Ming|Qiu, Jian-Ge|Zhang, Wen-Ji|Jiang, Qi-Wei|Xue, You-Qiu|Zheng, Di-Wei|Chen, Yao|Qin, Wu-Ming|Wei, Meng-Ning|Shi, Zhi
PMID: 26807313
Journal: Mol Carcinog. 2016 Jun;55(6):1096-110.
Title: Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells.
Author: Kim, Do-Hee|Park, Ki-Woong|Chae, In Gyeong|Kundu, Juthika|Kim, Eun-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 26152521
Journal: J Cell Biochem. 2016 May;117(5):1262-72.
Title: Crataegus azarolus Leaves Induce Antiproliferative Activity, Cell Cycle Arrest, and Apoptosis in Human HT-29 and HCT-116 Colorectal Cancer Cells.
Author: Mustapha, Nadia|Pinon, Aline|Limami, Youness|Simon, Alain|Ghedira, Kamel|Hennebelle, Thierry|Chekir-Ghedira, Leila
PMID: 26495895
Journal: Oncotarget. 2016 Jan 5;7(1):622-37.
Title: Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer.
Author: Thorenoor, Nithyananda|Faltejskova-Vychytilova, Petra|Hombach, Sonja|Mlcochova, Jitka|Kretz, Markus|Svoboda, Marek|Slaby, Ondrej
PMID: 26506418
Journal: Food Chem Toxicol. 2016 Jan;87:1-11.
Title: A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells.
Author: Wani, Zahoor Ahmad|Guru, Santosh Kumar|Rao, A V Subba|Sharma, Sonia|Mahajan, Girish|Behl, Akanksha|Kumar, Ashok|Sharma, P R|Kamal, Ahmed|Bhushan, Shashi|Mondhe, Dilip M
PMID: 26615871
Journal: Oncotarget. 2016 Jan 19;7(3):3186-200.
Title: Combination of tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species.
Author: Sankpal, Umesh T|Nagaraju, Ganji Purnachandra|Gottipolu, Sriharika R|Hurtado, Myrna|Jordan, Christopher G|Simecka, Jerry W|Shoji, Mamoru|El-Rayes, Bassel|Basha, Riyaz
PMID: 26672603
Journal: J Enzyme Inhib Med Chem. 2016 Dec;31(6):1286-99.
Title: Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells.
Author: Malki, Ahmed|Ashour, Hayam M A|Elbayaa, Rasha Y|Issa, Doaa A E|Aziz, Hassan A|Chen, Xiaozhuo
PMID: 26677729
Journal: Oncol Rep. 2016 Feb;35(2):1091-100.
Title: Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
Author: Yousef, Bashir A|Guerram, Mounia|Hassan, Hozeifa M|Hamdi, Aida M|Zhang, Lu-Yong|Jiang, Zhen-Zhou
PMID: 26718323
Journal: J Nat Prod. 2016 Jan 22;79(1):2-12.
Title: Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria.
Author: Weidner, Christopher|Rousseau, Morten|Micikas, Robert J|Fischer, Cornelius|Plauth, Annabell|Wowro, Sylvia J|Siems, Karsten|Hetterling, Gregor|Kliem, Magdalena|Schroeder, Frank C|Sauer, Sascha
PMID: 26731300
Journal: Neoplasma. 2016;63(2):193-200.
Title: Chidamide and 5-flurouracil show a synergistic antitumor effect on human colon cancer xenografts in nude mice.
Author: Liu, L|Qiu, S|Liu, Y|Liu, Z|Zheng, Y|Su, X|Chen, B|Chen, H
PMID: 26774139
Journal: PLoS One. 2016 Jan 19;11(1):e0147218.
Title: Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis.
Author: Zhang, Jintao|Yi, Man|Zha, Longying|Chen, Siqiang|Li, Zhijia|Li, Cheng|Gong, Mingxing|Deng, Hong|Chu, Xinwei|Chen, Jiehua|Zhang, Zheqing|Mao, Limei|Sun, Suxia
PMID: 26784903
Journal: Oncologist. 2016 Feb;21(2):172-7.
Title: Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer.
Author: Leichman, Lawrence|Groshen, Susan|O'Neil, Bert H|Messersmith, Wells|Berlin, Jordan|Chan, Emily|Leichman, Cynthia G|Cohen, Steven J|Cohen, Deirdre|Lenz, Heinz-Josef|Gold, Philip|Boman, Bruce|Fielding, Anitra|Locker, Gershon|Cason, Ronald C|Hamilton, Stan R
PMID: 26786262
Journal: Biomol Ther (Seoul). 2016 Mar 1;24(2):140-6.
Title: Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer.
Author: Song, Hun Min|Park, Gwang Hun|Eo, Hyun Ji|Jeong, Jin Boo
PMID: 26797111
Journal: Chin J Integr Med. 2016 Jan 29. pii: 10.1007/s11655-015-2108-3.
Title: Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.
Author: Zhang, Lei-Lei|Si, Jian-Yong|Zhang, Li-Jing|Xiao-Wei, Huo|Lin, Li|Li, Ru-Yi|Chen, Dan|Cao, Li
PMID: 26825081
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Eur J Med Chem. 2016 Mar 23;111:183-92.
Title: Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity.
Author: He, Luwei|Han, Junjie|Li, Baowei|Huang, Li|Ma, Ke|Chen, Quan|Liu, Xinzhong|Bao, Li|Liu, Hongwei
PMID: 26871659
Journal: Fam Cancer. 2016 Jul;15(3):359-66.
Title: Hereditary cancer syndromes: utilizing DNA repair deficiency as therapeutic target.
Author: Goyal, Gaurav|Fan, Tiffany|Silberstein, Peter Todd
PMID: 26873719
Journal: Bull Cancer. 2016 Mar;103(3):227-35.
Title: [Dbait: An innovative concept to inhibit DNA repair and treat cancer].
Author: Biau, Julian|Devun, Flavien|Verrelle, Pierre|Dutreix, Marie
PMID: 26917468
Journal: PLoS One. 2016 Mar 1;11(3):e0150484.
Title: Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of beta-Catenin Degradation-Competent Axin Puncta.
Author: Martino-Echarri, Estefania|Brocardo, Mariana G|Mills, Kate M|Henderson, Beric R
PMID: 26930278
Journal: Oncotarget. 2016 Jun 14;7(24):37331-37346.
Title: The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer.
Author: Gao, Dan|Herman, James G|Guo, Mingzhou
PMID: 26967246
Journal: Cancer Res. 2016 May 15;76(10):2868-75.
Title: Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest.
Author: Schaaf, Lea|Schwab, Matthias|Ulmer, Christoph|Heine, Simon|Murdter, Thomas E|Schmid, Jens O|Sauer, Georg|Aulitzky, Walter E|van der Kuip, Heiko
PMID: 27013194
Journal: Toxicol Appl Pharmacol. 2016 Jun 1;300:1-12.
Title: Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line.
Author: Vendramini-Costa, Debora Barbosa|Alcaide, Antonio|Pelizzaro-Rocha, Karin Juliane|Talero, Elena|Avila-Roman, Javier|Garcia-Maurino, Sofia|Pilli, Ronaldo Aloise|de Carvalho, Joao Ernesto|Motilva, Virginia
PMID: 27016270
Journal: Colloids Surf B Biointerfaces. 2016 Jul 1;143:499-510.
Title: Polyphenol stabilized colloidal gold nanoparticles from Abutilon indicum leaf extract induce apoptosis in HT-29 colon cancer cells.
Author: Mata, Rani|Nakkala, Jayachandra Reddy|Sadras, Sudha Rani
PMID: 27038915
Journal: Mar Drugs. 2016 Mar 29;14(4). pii: md14040069.
Title: In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells.
Author: Eo, Hyun Ji|Kwon, Tae-Hyung|Park, Gwang Hun|Song, Hun Min|Lee, Su-Jin|Park, Nyun-Ho|Jeong, Jin Boo
PMID: 27043582
Journal: Colloids Surf B Biointerfaces. 2016 Aug 1;144:1-7.
Title: Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol.
Author: Summerlin, Natalie|Qu, Zhi|Pujara, Naisarg|Sheng, Yong|Jambhrunkar, Siddharth|McGuckin, Michael|Popat, Amirali
PMID: 27060664
Journal: J Nat Prod. 2016 Apr 22;79(4):1097-104.
Title: Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
Author: Kim, Won Kyung|Pyee, Yuna|Chung, Hwa-Jin|Park, Hyen Joo|Hong, Ji-Young|Son, Kun Ho|Lee, Sang Kook
PMID: 27064730
Journal: Cell Mol Biol (Noisy-le-grand). 2016 Mar 31;62(3):72-7.
Title: Human colon cancer HT-29 cell death responses to doxorubicin and Morus Alba leaves flavonoid extract.
Author: Fallah, S|Karimi, A|Panahi, G|Gerayesh Nejad, S|Fadaei, R|Seifi, M
PMID: 27064876
Journal: Invest New Drugs. 2016 Aug;34(4):450-7.
Title: A Phase I study of olaparib and irinotecan in patients with colorectal cancer: Canadian Cancer Trials Group IND 187.
Author: Chen, Eric X|Jonker, Derek J|Siu, Lillian L|McKeever, Karyn|Keller, Deborah|Wells, Julie|Hagerman, Linda|Seymour, Lesley
PMID: 27075016
Journal: Oncol Lett. 2016 May;11(5):3551-3557.
Title: 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane potentiates in vitro and in vivo antitumor effects of irinotecan on human colorectal cancer cells.
Author: Yang, Po-Sheng|Wang, Jane-Jen|Wang, Yea-Hwey|Jan, Woan-Ching|Cheng, Shih-Ping|Hsu, Yi-Chiung
PMID: 27123150
Journal: Mol Cancer Ther. 2016 Jul;15(7):1525-34.
Title: The Discovery and Characterization of K-756, a Novel Wnt/beta-Catenin Pathway Inhibitor Targeting Tankyrase.
Author: Okada-Iwasaki, Ryoko|Takahashi, Yuichi|Watanabe, Yasuo|Ishida, Hiroshi|Saito, Jun-Ichi|Nakai, Ryuichiro|Asai, Akira
PMID: 27196752
Journal: Sci Rep. 2016 May 20;6:26273.
Title: Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer.
Author: Ozden, Ozkan|Bishehsari, Faraz|Bauer, Jessica|Park, Seong-Hoon|Jana, Arundhati|Baik, Seung Hyun|Sporn, Judith C|Staudacher, Jonas J|Yazici, Cemal|Krett, Nancy|Jung, Barbara
PMID: 27197561
Journal: Chem Biol Interact. 2016 Aug 25;256:198-208.
Title: Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells.
Author: Shah, Aabid Manzoor|Wani, Abubakar|Qazi, Parvaiz H|Rehman, Shakeel-U|Mushtaq, Saleem|Ali, Shiekh Abid|Hussain, Aehtesham|Shah, Aiyatullah|Qazi, Asif Khurshid|Makhdoomi, Ubaid Sharif|Hamid, Abid|Kumar, Ajay
PMID: 27378626
Journal: Oncotarget. 2016 Jul 26;7(30):48027-48037.
Title: Dragon (RGMb) induces oxaliplatin resistance in colon cancer cells.
Author: Shi, Ying|Huang, Xiao-Xiao|Chen, Guo-Bin|Wang, Ying|Zhi, Qiang|Liu, Yuan-Sheng|Wu, Xiao-Ling|Wang, Li-Fen|Yang, Bing|Xiao, Chuan-Xing|Xing, Hui-Qin|Ren, Jian-Lin|Xia, Yin|Guleng, Bayasi
PMID: 27384995
Journal: Acta Biomater. 2016 Sep 15;42:220-231.
Title: Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Ramasamy, Thiruganesh|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Yong, Chul Soon|Kim, Jong Oh|Kim, Hwan Mook
PMID: 27395829
Journal: Ann Surg Oncol. 2016 Nov;23(12):3924-3933.
Title: Immature Colon Carcinoma Transcript-1 (ICT1) Expression Correlates with Unfavorable Prognosis and Survival in Patients with Colorectal Cancer.
Author: Lao, Xinyuan|Feng, Qingyang|He, Guodong|Ji, Meiling|Zhu, Dexiang|Xu, Pingping|Tang, Wentao|Xu, Jianmin|Qin, Xinyu
PMID: 27411551
Journal: Int J Mol Sci. 2016 Jul 15;17(7). pii: ijms17071123.
Title: Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells.
Author: Karabay, Arzu Zeynep|Koc, Asli|Ozkan, Tulin|Hekmatshoar, Yalda|Sunguroglu, Asuman|Aktan, Fugen|Buyukbingol, Zeliha
PMID: 27428957
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2016 Jun 20;36(7):921-6.
Title: [Mechanism of colon cancer cell apoptosis induced by telocinobufagin: role of oxidative stress and apoptosis pathway].
Author: Liang, Shun-Tian|Li, Yuan|Li, Xiao-Wu|Wang, Jun-Jiang|Tan, Fu-Xian|Han, Qin-Rui|Li, Lu|Yao, Xue-Qing|Sun, Xue-Gang
PMID: 27435769
Journal: PLoS One. 2016 Aug 10;11(8):e0160961.
Title: miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.
Author: Kang, Moo Rim|Park, Ki Hwan|Yang, Jeong-Ook|Lee, Chang Woo|Oh, Soo Jin|Yun, Jieun|Lee, Myeong Youl|Han, Sang-Bae|Kang, Jong Soon
PMID: 27509128
Journal: Hered Cancer Clin Pract. 2016 Aug 23;14(1):17.
Title: Cytotoxic and targeted therapy for hereditary cancers.
Author: Iyevleva, Aglaya G|Imyanitov, Evgeny N
PMID: 27555886
Journal: Med Sci Monit. 2016 Sep 11;22:3215-22.
Title: Dimethoxy Curcumin Induces Apoptosis by Suppressing Survivin and Inhibits Invasion by Enhancing E-Cadherin in Colon Cancer Cells.
Author: Chen, Dong|Dai, Fang|Chen, Zhehang|Wang, Saisai|Cheng, Xiaobin|Sheng, Qinsong|Lin, Jianjiang|Chen, Wenbin
PMID: 27614381
Journal: Int J Oncol. 2016 Oct;49(4):1505-1512.
Title: Downregulation of RLIP76 is associated with vincristine resistance in human colorectal cancer HCT-8/VCR cells.
Author: Wang, Wenwen|Liu, Juan|Qi, Jianni|Zhang, Junyong|Zhu, Qiang|Ma, Jincai|Qin, Chengyong
PMID: 27633085
Journal: Int J Oncol. 2016 Nov;49(5):1953-1962.
Title: Knockdown of RPL9 expression inhibits colorectal carcinoma growth via the inactivation of Id-1/NF-kappaB signaling axis.
Author: Baik, In Hye|Jo, Guk-Heui|Seo, Daekwan|Ko, Min Ji|Cho, Chi Heum|Lee, Min Goo|Lee, Yun-Han
PMID: 27633352
Journal: Inflamm Bowel Dis. 2016 Nov;22(11):2593-2606.
Title: Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes.
Author: Kruse, Marie-Luise|Friedrich, Martin|Arlt, Alexander|Rocken, Christoph|Egberts, Jan-Hendrik|Sebens, Susanne|Schafer, Heiner
PMID: 27661668
Journal: Nucleic Acids Res. 2016 Dec 1;44(21):10386-10405.
Title: Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.
Author: Rank, Lisa|Veith, Sebastian|Gwosch, Eva C|Demgenski, Janine|Ganz, Magdalena|Jongmans, Marjolijn C|Vogel, Christopher|Fischbach, Arthur|Buerger, Stefanie|Fischer, Jan M F|Zubel, Tabea|Stier, Anna|Renner, Christina|Schmalz, Michael|Beneke, Sascha|Groettrup,
PMID: 27694308
Journal: J Agric Food Chem. 2016 Oct 11.
Title: Stereoisomers of Astaxanthin Inhibit Human Colon Cancer Cell Growth by Inducing G2/M Cell Cycle Arrest and Apoptosis.
Author: Liu, Xiaojuan|Song, Mingyue|Gao, Zili|Cai, Xiaokun|Dixon, William|Chen, Xiaofeng|Cao, Yong|Xiao, Hang
PMID: 27726394
Journal: Dis Markers. 2016;2016:8289293.
Title: The Effect of Poly(ADP-ribose) Polymerase-1 Gene 3'Untranslated Region Polymorphism in Colorectal Cancer Risk among Saudi Cohort.
Author: Alhadheq, Abdullah M|Purusottapatnam Shaik, Jilani|Alamri, Abdullah|Aljebreen, Abdulrahman M|Alharbi, Othman|Almadi, Majid A|Alhadeq, Faten|Azzam, Nahla A|Semlali, Abdelhabib|Alanazi, Mohammad|Bazzi, Mohammad D|Reddy Parine, Narasimha
PMID: 27746584
Journal: Int J Mol Sci. 2016 Oct 18;17(10). pii: ijms17101653.
Title: Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-beta-Cyclodextrin (DEN-HPbetaCD).
Author: Ashwaq, Al-Abboodi Shakir|Al-Qubaisi, Mothanna Sadiq|Rasedee, Abdullah|Abdul, Ahmad Bustamam|Taufiq-Yap, Yun Hin|Yeap, Swee Keong
PMID: 27763535
Journal: Food Funct. 2016 Dec 7;7(12):4797-4803.
Title: The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-kappaB signaling pathway.
Author: Hsieh, Shu-Chen|Hsieh, Wang-Ju|Chiang, An-Na|Su, Nan-Wei|Yeh, Yu-Te|Liao, Yi-Chun
PMID: 27869910
Journal: Oncotarget. 2016 Dec 27;7(52):87417-87430.
Title: The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition.
Author: McAndrew, Erin N|Lepage, Chloe C|McManus, Kirk J
PMID: 27902462
Journal: J Cancer Prev. 2016 Dec;21(4):249-256.
Title: Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells.
Author: Oh, You Na|Jin, Soojung|Park, Hyun-Jin|Kwon, Hyun Ju|Kim, Byung Woo
PMID: 28053959
Journal: World J Gastroenterol. 2016 Dec 28;22(48):10680-10686.
Title: Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.
Author: Ghiringhelli, Francois|Richard, Corentin|Chevrier, Sandy|Vegran, Frederique|Boidot, Romain
PMID: 28082821
Journal: Oncol Lett. 2016 Dec;12(6):5211-5216.
Title: Naphthazarin suppresses cell proliferation and induces apoptosis in human colorectal cancer cells via the B-cell lymphoma 2/B-cell associated X protein signaling pathway.
Author: Chen, Ai-Dong|Li, Hui|Li, Yong-Chun|Zeng, Hai
PMID: 28101239
Journal: J Tradit Chin Med. 2016 Aug;36(4):514-21.
Title: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
Author: Shen, Li|Lou, Zhaohuan|Zhang, Guangshun|Xu, Guanhua|Zhang, Guangji
PMID: 28459519
Journal: J Inorg Biochem. 2017 Jan;166:34-48.
Title: New dibutyltin(IV) ladders: Syntheses, structures and, optimization and evaluation of cytotoxic potential employing A375 (melanoma) and HCT116 (colon carcinoma) cell lines in vitro.
Author: Basu Baul, Tushar S|Dutta, Dhrubajyoti|Duthie, Andrew|Guchhait, Nikhil|Rocha, Bruno G M|Guedes da Silva, M Fatima C|Mokhamatam, Raveendra B|Raviprakash, Nune|Manna, Sunil K
PMID: 27815980
Journal: Biochem Pharmacol. 2017 Feb 1;125:12-25.
Title: Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells.
Author: Tao, Lei|Wei, Libing|Liu, Yishi|Ding, Yang|Liu, Xiuting|Zhang, Xin|Wang, Xiaoping|Yao, Yuyuan|Lu, Jinrong|Wang, Qing|Hu, Rong
PMID: 27818240
Journal: Acta Pharmacol Sin. 2017 Feb;38(2):252-263.
Title: Oblongifolin C and guttiferone K extracted from Garcinia yunnanensis fruit synergistically induce apoptosis in human colorectal cancer cells in vitro.
Author: Li, Hui|Meng, Xiao-Xiao|Zhang, Li|Zhang, Bao-Jun|Liu, Xin-Yu|Fu, Wen-Wei|Tan, Hong-Sheng|Lao, Yuan-Zhi|Xu, Hong-Xi
PMID: 27840412
Journal: J Pineal Res. 2017 Mar;62(2).
Title: Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-kappaB/iNOS signaling pathways.
Author: Gao, Yue|Xiao, Xiangsheng|Zhang, Changlin|Yu, Wendan|Guo, Wei|Zhang, Zhifeng|Li, Zhenglin|Feng, Xu|Hao, Jiaojiao|Zhang, Kefang|Xiao, Bingyi|Chen, Miao|Huang, Wenlin|Xiong, Shunbin|Wu, Xiaojun|Deng, Wuguo
PMID: 27865009
Journal: Int J Oncol. 2017 Jan;50(1):283-289.
Title: 2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression.
Author: Nguyen, Hai-Anh|Kim, Soo-A
PMID: 27922674
Journal: Oncol Rep. 2017 Mar;37(3):1786-1792.
Title: Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells.
Author: Yang, Jai-Sing|Lin, Chia-An|Lu, Chi-Cheng|Wen, Yen-Fang|Tsai, Fuu-Jen|Tsai, Shih-Chang
PMID: 28098885
Journal: Mol Cancer Res. 2017 Feb;15(2):141-151.
Title: Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-kappaB Activation.
Author: Kim, Se-Lim|Kim, Seong Hun|Park, Young Ran|Liu, Yu-Chuan|Kim, Eun-Mi|Jeong, Hwan-Jeong|Kim, Yo Na|Seo, Seung Young|Kim, In Hee|Lee, Seung Ok|Lee, Soo Teik|Kim, Sang-Wook
PMID: 28108625
Journal: Mol Oncol. 2017 May;11(5):470-490.
Title: Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Author: Kalimutho, Murugan|Bain, Amanda L|Mukherjee, Bipasha|Nag, Purba|Nanayakkara, Devathri M|Harten, Sarah K|Harris, Janelle L|Subramanian, Goutham N|Sinha, Debottam|Shirasawa, Senji|Srihari, Sriganesh|Burma, Sandeep|Khanna, Kum Kum
PMID: 28173629
Journal: Transl Oncol. 2017 Apr;10(2):190-196.
Title: ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib.
Author: Wang, Chen|Jette, Nicholas|Moussienko, Daniel|Bebb, D Gwyn|Lees-Miller, Susan P
PMID: 28182994
Journal: Free Radic Biol Med. 2017 May;106:24-37.
Title: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author: Wang, Gangyang|Zhang, Tao|Sun, Wei|Wang, Hongsheng|Yin, Fei|Wang, Zhuoying|Zuo, Dongqing|Sun, Mengxiong|Zhou, Zifei|Lin, Binhui|Xu, Jing|Hua, Yingqi|Li, Haoqing|Cai, Zhengdong
PMID: 28188923
Journal: Cancer Lett. 2017 May 1;393:103-112.
Title: Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2.
Author: Badawi, Amel|Hehlgans, Stephanie|Pfeilschifter, Josef|Rodel, Franz|Eberhardt, Wolfgang
PMID: 28219770
Journal: Oncol Rep. 2017 Apr;37(4):2079-2086.
Title: A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells.
Author: Dai, Xiaoli|Liu, Jing|Nian, Yin|Qiu, Ming-Hua|Luo, Ying|Zhang, Jihong
PMID: 28260002
Journal: Curr Med Chem. 2017;24(20):2156-2173.
Title: Expression and Single Nucleotide Polymorphism of Poly (ADPRibose) Polymerase-1 in Gastrointestinal Tumours: Clinical Involvement.
Author: Martin-Guerrero, Sandra M|Leon, Josefa|Quiles-Perez, Rosa|Belmonte, Laura|Martin-Oliva, David|Ruiz-Extremera, Angeles|Salmeron, Javier|Munoz-Gamez, Jose Antonio
PMID: 28302009
Journal: Nutr Cancer. 2017 May-Jun;69(4):674-681.
Title: Antiproliferative Activity of Egg Yolk Peptides in Human Colon Cancer Cells.
Author: Yousr, Marwa N|Aloqbi, Akram A|Omar, Ulfat M|Howell, Nazlin K
PMID: 28323499
Journal: Eur J Pharmacol. 2017 Jul 15;807:21-31.
Title: In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor.
Author: Nishizawa, Satoru|Sumi, Hiroyuki|Satoh, Yoshihiko|Yamamoto, Yukiko|Kitazawa, Satoshi|Honda, Kohei|Araki, Hideo|Kakoi, Kazuyo|Imamura, Keisuke|Sasaki, Masako|Miyahisa, Ikuo|Satomi, Yoshinori|Nishigaki, Ryuuichi|Hirayama, Megumi|Aoyama, Kazunobu|Maezaki, Hi
PMID: 28442322
Journal: Int J Biochem Cell Biol. 2017 Jul;88:1-13.
Title: HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer.
Author: Mansour, Mohammed A|Senga, Takeshi
PMID: 28457970
Journal: Immune Netw. 2017 Apr;17(2):110-115.
Title: Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells.
Author: Ndolo, Karyn Muzinga|Park, Kyeong Ryang|Lee, Hyo Jeong|Yoon, Kyoung Bin|Kim, Yong-Chul|Han, Sun-Young
PMID: 28458622
Journal: BMC Pharmacol Toxicol. 2017 May 4;18(1):32.
Title: Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line.
Author: Kustiawan, Paula Mariana|Lirdprapamongkol, Kriengsak|Palaga, Tanapat|Puthong, Songchan|Phuwapraisirisan, Preecha|Svasti, Jisnuson|Chanchao, Chanpen
PMID: 28472978
Journal: Lancet Gastroenterol Hepatol. 2017 Jun;2(6):389-390.
Title: PARP inhibitors and chemoradiation for rectal cancer.
Author: Glynne-Jones, Rob|Hall, Marcia
PMID: 28497749
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 May;33(5):606-610.
Title: [Knock-down of cadherin 17 inhibits proliferation and promote apoptosis in noscapine-resistant human SW480 colon cancer cells].
Author: Han, Zheng|Huang, Xiaodong|Liu, Meng|Tan, Jie|Zhu, Qingxi|Wang, Yanfen|Cai, Yishan|Chen, Aifang|Tian, Xia
PMID: 28502297
Journal: J Med Food. 2017 May;20(5):485-490.
Title: Mammea longifolia Planch. and Triana Fruit Extract Induces Cell Death in the Human Colon Cancer Cell Line, SW480, via Mitochondria-Related Apoptosis and Activation of p53.
Author: Li, Chunmei|Jeong, Yoonhwa|Kim, Misook
PMID: 28504908
Journal: Anticancer Res. 2017 Jun;37(6):2975-2984.
Title: Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Author: Yun, Seungpil|Han, Yong-Seok|Lee, Jun Hee|Kim, Sangmin|Lee, Sang Hun
PMID: 28551635
Journal: BMC Genomics. 2017 May 30;18(1):421.
Title: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author: Cong, Wang|Meng, Xianglian|Li, Jin|Zhang, Qiushi|Chen, Feng|Liu, Wenjie|Wang, Ying|Cheng, Sipu|Yao, Xiaohui|Yan, Jingwen|Kim, Sungeun|Saykin, Andrew J|Liang, Hong|Shen, Li
PMID: 28558704
Journal: Oncotarget. 2017 Jul 18;8(29):47902-47915.
Title: mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Author: Mashima, Tetsuo|Taneda, Yoko|Jang, Myung-Kyu|Mizutani, Anna|Muramatsu, Yukiko|Yoshida, Haruka|Sato, Ayana|Tanaka, Noritaka|Sugimoto, Yoshikazu|Seimiya, Hiroyuki
PMID: 28615517
Journal: Int J Oncol. 2017 Aug;51(2):615-624.
Title: 18 beta-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Author: Wang, Saisai|Shen, Yong|Qiu, Runfeng|Chen, Zhiliang|Chen, Zhehang|Chen, Wenbin
PMID: 28656212
Journal: Nat Commun. 2017 Jun 28;8(1):40.
Title: Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells.
Author: Kang, Dong Hoon|Lee, Doo Jae|Lee, Sunmi|Lee, So-Young|Jun, Yukyung|Kim, Yerin|Kim, Youngeun|Lee, Ju-Seog|Lee, Dae-Kee|Lee, Sanghyuk|Jho, Eek-Hoon|Yu, Dae-Yeul|Kang, Sang Won
PMID: 28659575
Journal: BMB Rep. 2017 Aug;50(8):391-392.
Title: Survival of APC-mutant colorectal cancer cells requires interaction between tankyrase and a thiol peroxidase, peroxiredoxin II.
Author: Kang, Dong Hoon|Lee, Joanna H S|Kang, Sang Won
PMID: 28683851
Journal: World J Gastroenterol. 2017 Jun 28;23(24):4341-4353.
Title: Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells.
Author: Tischlerova, Viera|Kello, Martin|Budovska, Mariana|Mojzis, Jan
PMID: 28706417
Journal: Int J Oncol. 2017 Sep;51(3):959-966.
Title: Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway.
Author: Park, Sun-Young|Oh, Hyung-Hoon|Park, Young-Lan|Yu, Hyung-Min|Myung, Dae-Seong|Cho, Sung-Bum|Lee, Wan-Sik|Park, Daeho|Joo, Young-Eun
PMID: 28713983
Journal: Mar Drugs. 2017 Jul 20;15(7). pii: md15070221.
Title: Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-kappaB Signaling.
Author: Tarhouni-Jabberi, Safa|Zakraoui, Ons|Ioannou, Efstathia|Riahi-Chebbi, Ichrak|Haoues, Meriam|Roussis, Vassilios|Kharrat, Riadh|Essafi-Benkhadir, Khadija
PMID: 28726723
Journal: Oncol Rep. 2017 Sep;38(3):1783-1789.
Title: MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.
Author: Hwang, Na Lam|Kang, Yong Jung|Sung, Bokyung|Hwang, Seong Yeon|Jang, Jung Yoon|Oh, Hye Jin|Ahn, Yu Ra|Kim, Do Hyun|Kim, Su Jeong|Ullah, Sultan|Hossain, Mohammad Akbar|Moon, Hyung Ryong|Chung, Hae Young|Kim, Nam Deuk
PMID: 28731136
Journal: J Gastrointest Oncol. 2017 Jun;8(3):405-417.
Title: Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment.
Author: Verdaguer, Helena|Sauri, Tamara|Macarulla, Teresa
PMID: 28736628
Journal: Clin Transl Gastroenterol. 2017 Jul 27;8(7):e109.
Title: The Association of Low-Penetrance Variants in DNA Repair Genes with Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author: Aggarwal, Nikhil|Donald, Neil D|Malik, Salim|Selvendran, Subothini S|McPhail, Mark Jw|Monahan, Kevin J
PMID: 28749454
Journal: Chem Biol Interact. 2017 Sep 25;275:162-170.
Title: Antitumor activity of beta-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways.
Author: Daaboul, Hamid E|Daher, Costantine F|Bodman-Smith, Kikki|Taleb, Robin I|Shebaby, Wassim N|Boulos, Joelle|Dagher, Carole|Mroueh, Mohamad A|El-Sibai, Mirvat
PMID: 28782499
Journal: Oncol Rep. 2017 Oct;38(4):2480-2488.
Title: Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Author: Wu, Wei|Chen, Jingdi|Wu, Jicheng|Lin, Jun|Yang, Sheng|Yu, Honggang
PMID: 28849218
Journal: Oncotarget. 2017 Jan 31;8(33):54199-54214.
Title: Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy.
Author: Leguisamo, Natalia M|Gloria, Helena C|Kalil, Antonio N|Martins, Talita V|Azambuja, Daniel B|Meira, Lisiane B|Saffi, Jenifer
PMID: 28903334
Journal: J Inorg Biochem. 2017 Dec;177:27-38.
Title: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells.
Author: Dandash, Fatima|Leger, David Yannick|Fidanzi-Dugas, Chloe|Nasri, Soumaya|Bregier, Frederique|Granet, Robert|Karam, Walid|Diab-Assaf, Mona|Sol, Vincent|Liagre, Bertrand
PMID: 28923355
Journal: Nutrients. 2017 Sep 21;9(10). pii: nu9101051.
Title: Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression.
Author: Jaksevicius, Andrius|Carew, Mark|Mistry, Calli|Modjtahedi, Helmout|Opara, Elizabeth I
PMID: 28934138
Journal: Oncotarget. 2017 Apr 20;8(35):58587-58600.
Title: Targeting progastrin enhances radiosensitization of colorectal cancer cells.
Author: Kowalski-Chauvel, Aline|Gouaze-Andersson, Valerie|Vignolle-Vidoni, Alix|Delmas, Caroline|Toulas, Christine|Cohen-Jonathan-Moyal, Elizabeth|Seva, Catherine
PMID: 28938581
Journal: Sci Rep. 2017 Sep 29;7(1):12406.
Title: Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells.
Author: Wu, Tung-Yun|Cho, Ting-Yu|Lu, Chung-Kuang|Liou, Jing-Ping|Chen, Mei-Chuan
PMID: 28963527
Journal: Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):249-255.
Title: Improved chemoradiation treatment using trifluridine in human colorectal cancer cells in vitro.
Author: Matsuoka, Kazuaki|Kobunai, Takashi|Nukatsuka, Mamoru|Takechi, Teiji
PMID: 29024630
Journal: Mutagenesis. 2017 Oct 17;32(5):533-542.
Title: MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.
Author: Schneiderova, Michaela|Naccarati, Alessio|Pardini, Barbara|Rosa, Fabio|Gaetano, Cornelia Di|Jiraskova, Katerina|Opattova, Alena|Levy, Miroslav|Veskrna, Karel|Veskrnova, Veronika|Buchler, Tomas|Landi, Stefano|Vodicka, Pavel|Vymetalkova, Veronika
PMID: 29048575
Journal: Oncol Lett. 2017 Dec;14(6):8000-8006.
Title: In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway.
Author: Jin, Shao-Ju|Yang, Yun|Ma, Lei|Ma, Ben-Hui|Ren, Li-Ping|Guo, Liu-Cheng|Wang, Wen-Bao|Zhang, Yan-Xin|Zhao, Zhi-Jun|Cui, Mingchen
PMID: 29344242
Journal: Oncotarget. 2017 Dec 8;8(70):115164-115178.
Title: Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.
Author: Hong, Se Hoon|Lee, Dae-Hee|Lee, Young-Sun|Jo, Min Jee|Jeong, Yoon A|Kwon, William T|Choudry, Haroon A|Bartlett, David L|Lee, Yong J
PMID: 29383150
Journal: Anticancer Agents Med Chem. 2018 Feb 7;17(14):1942-1950.
Title: Thymol Elicits HCT-116 Colorectal Carcinoma Cell Death Through Induction of Oxidative Stress.
Author: Chauhan, Anil Kumar|Bahuguna, Ashutosh|Paul, Souren|Kang, Sun Chul
PMID: 28356011
Journal: Cell Cycle. 2018;17(5):557-567.
Title: CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.
Author: Hernandez-Borrero, Liz J|Zhang, Shengliang|Lulla, Amriti|Dicker, David T|El-Deiry, Wafik S
PMID: 28749203
Journal: Clin Cancer Res. 2018 Mar 1;24(5):1202-1215.
Title: NAMPT Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP.
Author: Lucena-Cacace, Antonio|Otero-Albiol, Daniel|Jimenez-Garcia, Manuel P|Munoz-Galvan, Sandra|Carnero, Amancio
PMID: 29203587
Journal: Oncol Rep. 2018 Mar;39(3):1387-1395.
Title: Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells.
Author: Zeng, Xianliang|Chen, Sizeng|Lin, Yanfeng|Ke, Zhao
PMID: 29328480
Journal: Eur J Med Chem. 2018 Feb 10;145:511-523.
Title: Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents.
Author: Gupta, Nidhi|Qayum, Arem|Raina, Arun|Shankar, Ravi|Gairola, Sumeet|Singh, Shashank|Sangwan, Payare L
PMID: 29335212
Journal: Biosci Rep. 2018 Feb 21;38(1). pii: BSR20171428.
Title: Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer.
Author: Hu, Hanqing|Wang, Meng|Guan, Xu|Yuan, Ziming|Liu, Zheng|Zou, Chaoxia|Wang, Guiyu|Gao, Xu|Wang, Xishan
PMID: 29371412
Journal: Anticancer Drugs. 2018 Mar;29(3):234-242.
Title: Dioscin inhibits colon cancer cells' growth by reactive oxygen species-mediated mitochondrial dysfunction and p38 and JNK pathways.
Author: Li, Shu|Cheng, Binbin|Hou, Lixin|Huang, Lanwei|Cui, Yongkang|Xu, Duo|Shen, Xiaoping|Li, Shuang
PMID: 29389802
Journal: Phytother Res. 2018 Apr;32(4):657-666.
Title: Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen).
Author: Uto, Takuhiro|Tung, Nguyen Huu|Ohta, Tomoe|Juengsanguanpornsuk, Wipawee|Hung, Le Quoc|Hai, Nguyen Thanh|Long, Dinh Doan|Thuong, Phuong Thien|Okubo, Shinya|Hirata, Sakiko|Shoyama, Yukihiro
PMID: 29464799
Journal: Biomed Pharmacother. 2018 May;101:414-421.
Title: A silyl andrographolide analogue suppresses Wnt/beta-catenin signaling pathway in colon cancer.
Author: Reabroi, Somrudee|Chairoungdua, Arthit|Saeeng, Rungnapha|Kasemsuk, Teerapich|Saengsawang, Witchuda|Zhu, Weiming|Piyachaturawat, Pawinee
PMID: 29501763
Journal: Int J Oncol. 2018 Mar 7.
Title: Apigenin induces apoptosis by suppressing Bcl-xl and Mcl-1 simultaneously via signal transducer and activator of transcription 3 signaling in colon cancer.
Author: Maeda, Yuzo|Takahashi, Hiroki|Nakai, Nozomu|Yanagita, Takeshi|Ando, Nanako|Okubo, Tomotaka|Saito, Kenta|Shiga, Kazuyoshi|Hirokawa, Takahisa|Hara, Masayasu|Ishiguro, Hideyuki|Matsuo, Yoichi|Takiguchi, Shuji
PMID: 29512707
Journal: Molecules. 2018 Mar 14;23(3). pii: molecules23030658.
Title: Anti-Cancer Activity of Lobaric Acid and Lobarstin Extracted from the Antarctic Lichen Stereocaulon alpnum.
Author: Hong, Ju-Mi|Suh, Sung-Suk|Kim, Tai Kyoung|Kim, Jung Eun|Han, Se Jong|Youn, Ui Joung|Yim, Joung Han|Kim, Il-Chan
PMID: 29538328
Journal: Molecules. 2018 Mar 22;23(4). pii: molecules23040723.
Title: Food Additive Sodium Benzoate (NaB) Activates NFkappaB and Induces Apoptosis in HCT116 Cells.
Author: Yilmaz, Betul|Karabay, Arzu Zeynep
PMID: 29565269
Journal: Mol Biol Rep. 2018 Jun;45(3):373-377.
Title: Anticancer effect of fermented Insampaedok-san in human colon cancer cells: a pilot study.
Author: Park, Hwayong|Kim, Kwang Dong
PMID: 29611024
Journal: Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070.
Title: PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.
Author: Dorsam, Bastian|Seiwert, Nina|Foersch, Sebastian|Stroh, Svenja|Nagel, Georg|Begaliew, Diana|Diehl, Erika|Kraus, Alexander|McKeague, Maureen|Minneker, Vera|Roukos, Vassilis|Reissig, Sonja|Waisman, Ari|Moehler, Markus|Stier, Anna|Mangerich, Aswin|Dantzer, F
PMID: 29632181
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2600-2609.
Title: Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells.
Author: Kawaguchi, Nao|Tashiro, Keitaro|Taniguchi, Kohei|Kawai, Masaru|Tanaka, Keitaro|Okuda, Junji|Hayashi, Michihiro|Uchiyama, Kazuhisa
PMID: 29684585
Journal: Nutrients. 2018 May 1;10(5). pii: nu10050560.
Title: Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells.
Author: Attoub, Samir|Arafat, Kholoud|Khalaf, Tamam|Sulaiman, Shahrazad|Iratni, Rabah
PMID: 29724012
Journal: PLoS One. 2018 May 17;13(5):e0197563.
Title: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol.
Author: Wang, Jingqiu|Fang, Xianying|Ge, Lin|Cao, Fuliang|Zhao, Linguo|Wang, Zhenzhong|Xiao, Wei
PMID: 29771951
Journal: BMC Cancer. 2018 May 21;18(1):578.
Title: Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK.
Author: Gong, Xianling|Chen, Zhihong|Han, Qinrui|Chen, Chunhui|Jing, Linlin|Liu, Yawei|Zhao, Liang|Yao, Xueqing|Sun, Xuegang
PMID: 29783958
Journal: Sci Rep. 2018 May 21;8(1):7924.
Title: The anti-cancer activity of an andrographolide analogue functions through a GSK-3beta-independent Wnt/beta-catenin signaling pathway in colorectal cancer cells.
Author: Reabroi, Somrudee|Saeeng, Rungnapha|Boonmuen, Nittaya|Kasemsuk, Teerapich|Saengsawang, Witchuda|Suksen, Kanoknetr|Zhu, Weiming|Piyachaturawat, Pawinee|Chairoungdua, Arthit
PMID: 29784906
Journal: Phytother Res. 2018 Jun 7.
Title: Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells.
Author: Kim, Dong Hee|Shin, Eun Ah|Kim, Bonglee|Shim, Bum Sang|Kim, Sung-Hoon
PMID: 29876988
Journal: Cancer Discov. 2018 Aug;8(8):988-1005.
Title: MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.
Author: Sakthianandeswaren, Anuratha|Parsons, Marie J|Mouradov, Dmitri|MacKinnon, Ruth N|Catimel, Bruno|Liu, Sheng|Palmieri, Michelle|Love, Christopher|Jorissen, Robert N|Li, Shan|Whitehead, Lachlan|Putoczki, Tracy L|Preaudet, Adele|Tsui, Cary|Nowell, Cameron J|W
PMID: 29880585
Journal: Int J Biol Macromol. 2018 Oct 1;117:1050-1057.
Title: Pea lectin inhibits cell growth by inducing apoptosis in SW480 and SW48 cell lines.
Author: Islam, Farhadul|Gopalan, Vinod|Lam, Alfred K-Y|Kabir, Syed Rashel
PMID: 29885391
Journal: Int J Mol Med. 2018 Sep;42(3):1295-1304.
Title: Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunateinduced apoptosis.
Author: Jiang, Feng|Zhou, Jin-Yong|Zhang, Dan|Liu, Ming-Hao|Chen, Yu-Gen
PMID: 29901098
Journal: Cancer Commun (Lond). 2018 Jul 3;38(1):43.
Title: Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo.
Author: Qiao, Xinran|Wang, Xiaofei|Shang, Yue|Li, Yi|Chen, Shu-Zhen
PMID: 29970185
Journal: Bioorg Med Chem Lett. 2018 Sep 15;28(17):2869-2874.
Title: Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer.
Author: Lu, Shan|Obianom, Obinna N|Ai, Yong
PMID: 30037494
Journal: Cancer Chemother Pharmacol. 2018 Oct;82(4):635-647.
Title: Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Author: Jain, Mukul R|Mohapatra, Jogeswar|Bandhyopadhyay, Debdutta|Chatterjee, Abhijit|Ghoshdastidar, Krishnarup|Patel, Dinesh|Patel, Ankit|Bhayani, Hitesh|Srivastava, Brijesh Kumar|Shedage, Sandeep A|Kadam, Pravin|Sundar, Rajesh|Patel, Harilal|Giri, Poonam|Patel
PMID: 30046848
Journal: Int J Biochem Cell Biol. 2018 Oct;103:89-98.
Title: Lysosomal permeabilization and endoplasmic reticulum stress mediate the apoptotic response induced after photoactivation of a lipophilic zinc(II) phthalocyanine.
Author: Chiarante, Nicolas|Garcia Vior, Maria C|Rey, Osvaldo|Marino, Julieta|Roguin, Leonor P
PMID: 30130653
Journal: Oncotarget. 2018 Aug 17;9(64):32305-32320.
Title: Terpenes from essential oils and hydrolate of Teucrium alopecurus triggered apoptotic events dependent on caspases activation and PARP cleavage in human colon cancer cells through decreased protein expressions.
Author: Guesmi, Fatma|Tyagi, Amit K|Prasad, Sahdeo|Landoulsi, Ahmed
PMID: 30190788
Journal: J Biomol Struct Dyn. 2018 Sep 11:1-29.
Title: In silico insights on Tankyrase protein: a potential target for colorectal cancer.
Author: Lakshmanan, Loganathan|Muthusamy, Karthikeyan|Marshal, Jayaraj John|Kajamaideen, Afrinrilwana|Balthasar, Josephine Julia
PMID: 30204055
Journal: J Agric Food Chem. 2018 Sep 26;66(38):9960-9967.
Title: Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells.
Author: Choi, Jhin-Baek|Kim, Ju-Ha|Lee, Hyemin|Pak, Ji-Na|Shim, Bum Sang|Kim, Sung-Hoon
PMID: 30211553
Journal: Pharmacology. 2018 Sep 18;102(5-6):262-271.
Title: MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells.
Author: Lee, Chih-Hsin|Lin, Yuan-Feng|Chen, Yen-Chou|Wong, Shuit-Mun|Juan, Shu-Hui|Huang, Huei-Mei
PMID: 30227438
Journal: Oncotarget. 2018 Sep 4;9(69):33056-33058.
Title: MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer.
Author: Sakthianandeswaren, Anuratha|Parsons, Marie J|Mouradov, Dmitri|Sieber, Oliver M
PMID: 30237848
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Sep 26;1864(12):3668-3678.
Title: Senescence marker protein 30 protects intestinal epithelial cells against inflammation-induced cell death by enhancing Nrf2 activity.
Author: Choo, Jieun|Heo, Gwangbeom|Kim, Su Jin|Lee, Yunna|Ishigami, Akihito|Maruyama, Naoki|Chung, Hae Young|Im, Eunok
PMID: 30266650
Journal: Bull Cancer. 2018 Oct 8. pii: S0007-4551(18)30275-3.
Title: PTBP1 promotes tumorigenesis by regulating apoptosis and cell cycle in colon cancer.
Author: Li, Xiaona|Han, Fei|Liu, Wenbin|Shi, Xiaoyan
PMID: 30309622
Journal: Gastroenterology. 2018 Oct 17. pii: S0016-5085(18)35161-8.
Title: Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
Author: Wang-Bishop, Lihong|Chen, Zheng|Gomaa, Ahmed|Lockhart, Albert Craig|Salaria, Safia|Wang, Jialiang|Lewis, Keeli B|Ecsedy, Jeffrey|Washington, Kay|Beauchamp, Robert Daniel|El-Rifai, Wael
PMID: 30342037
Journal: Stem Cells. 2018 Oct 23.
Title: PARP inhibition sensitizes colorectal cancer-initiating cells to chemotherapy.
Author: Jarrar, Awad|Lotti, Fiorenza|DeVecchio, Jennifer|Ferrandon, Sylvain|Gantt, Gerald|Mace, Adam|Karagkounis, Georgios|Orloff, Matthew|Venere, Monica|Hitomi, Masahiro|Lathia, Justin|Rich, Jeremy N|Kalady, Matthew F
PMID: 30353615
Journal: Oncol Rep. 2018 Oct 22.
Title: Galla Rhois water extract inhibits lung metastasis by inducing AMPKmediated apoptosis and suppressing metastatic properties of colorectal cancer cells.
Author: Mun, Jeong-Geon|Kee, Ji-Ye|Han, Yo-Han|Lee, Sullim|Park, Seong-Hwan|Jeon, Hee Dong|Hong, Seung-Heon
PMID: 30365120
Journal: Eur J Med Chem. 2018 Oct 23;161:456-467.
Title: ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
Author: Narayan, Satya|Ramisetti, Srinivasa|Jaiswal, Aruna S|Law, Brian K|Singh-Pillay, Ashona|Singh, Parvesh|Amin, Shantu|Sharma, Arun K
PMID: 30384048