Primary Site >> Colorectal Cancer

Gene >> PAK4

Journal: J Biol Chem. 2002 Jan 4;277(1):550-8. Epub 2001 Oct 19.
Title: Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.
Author: Callow, Marinella G|Clairvoyant, Felix|Zhu, Shirley|Schryver, Brian|Whyte, David B|Bischoff, James R|Jallal, Bahija|Smeal, Tod
PMID: 11668177
Journal: Biochem Biophys Res Commun. 2012 Oct 26;427(3):444-9.
Title: MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells.
Author: Wang, Zhigang|Zhang, Xiaoping|Yang, Zhili|Du, Hangxiang|Wu, Zhenqian|Gong, Jianfeng|Yan, Jun|Zheng, Qi
PMID: 22766504
Journal: Mol Cancer Res. 2013 Feb;11(2):109-21.
Title: Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author: Tabusa, Hana|Brooks, Teresa|Massey, Andrew J
PMID: 23233484
Journal: Cancer Lett. 2013 Jul 28;335(2):332-42.
Title: Tumor-suppressive microRNA-145 targets catenin delta-1 to regulate Wnt/beta-catenin signaling in human colon cancer cells.
Author: Yamada, Nami|Noguchi, Shunsuke|Mori, Takashi|Naoe, Tomoki|Maruo, Kohji|Akao, Yukihiro
PMID: 23499891
Journal: Carcinogenesis. 2014 Mar;35(3):624-34.
Title: SH3RF2 functions as an oncogene by mediating PAK4 protein stability.
Author: Kim, Tae Woo|Kang, Yun Kyung|Park, Zee Yong|Kim, Young-Ho|Hong, Seong Woo|Oh, Su Jin|Sohn, Hyun Ahm|Yang, Suk-Jin|Jang, Ye Jin|Lee, Dong Chul|Kim, Se-Yong|Yoo, Hyang-Sook|Kim, Eunhee|Yeom, Young Il|Park, Kyung Chan
PMID: 24130170
Journal: J Cell Sci. 2014 Jul 15;127(Pt 14):3116-30.
Title: The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of beta-catenin through mechanisms involving FRAT1 and PAK4.
Author: Jin, Runsen|Liu, Wensheng|Menezes, Sharleen|Yue, Fei|Zheng, Minhua|Kovacevic, Zaklina|Richardson, Des R
PMID: 24829151
Journal: J Surg Res. 2015 Jun 1;196(1):130-5.
Title: P21-activated kinase 1 and 4 were associated with colorectal cancer metastasis and infiltration.
Author: Song, Bao|Wang, Wei|Zheng, Yan|Yang, Jianshu|Xu, Zhongfa
PMID: 25791829
Journal: Cancer Med. 2017 Jun;6(6):1331-1340.
Title: MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
Author: Sheng, Nengquan|Tan, Gewen|You, Weiqiang|Chen, Hongqi|Gong, Jianfeng|Chen, Di|Zhang, Huizhen|Wang, Zhigang
PMID: 28440035
Journal: Cell Death Dis. 2017 May 25;8(5):e2820.
Title: PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth.
Author: Zhang, Xiumei|Zhang, Xia|Li, Yang|Shao, Yangguang|Xiao, Jianying|Zhu, Ge|Li, Feng
PMID: 28542136