Primary Site >> Colorectal Cancer

Gene >> PAH

Journal: Adv Enzyme Regul. 1998;38:207-22.
Title: AH receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms.
Author: Bock, K W|Gschaidmeier, H|Heel, H|Lehmkoster, T|Munzel, P A|Raschko, F|Bock-Hennig, B
PMID: 9762354
Journal: Cancer Res. 1999 Feb 1;59(3):607-14.
Title: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
Author: Burczynski, M E|Lin, H K|Penning, T M
PMID: 9973208
Journal: Arch Toxicol. 2002 Jun;76(5-6):287-98. Epub 2002 Apr 10.
Title: Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
Author: Iwanari, Masashi|Nakajima, Miki|Kizu, Ryoichi|Hayakawa, Kazuichi|Yokoi, Tsuyoshi
PMID: 12107646
Journal: Toxicol Sci. 2003 Apr;72(2):253-9. Epub 2003 Mar 7.
Title: Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines.
Author: Tsuchiya, Yuki|Nakajima, Miki|Itoh, Satsuki|Iwanari, Masashi|Yokoi, Tsuyoshi
PMID: 12655030
Journal: J Nutr. 2004 Apr;134(4):776-84.
Title: Meat consumption patterns and preparation, genetic variants of metabolic enzymes, and their association with rectal cancer in men and women.
Author: Murtaugh, Maureen A|Ma, Khe-Ni|Sweeney, Carol|Caan, Bette J|Slattery, Martha L
PMID: 15051825
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1626-32.
Title: Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer.
Author: Butler, Lesley M|Duguay, Yannick|Millikan, Robert C|Sinha, Rashmi|Gagne, Jean-Francois|Sandler, Robert S|Guillemette, Chantal
PMID: 16030093
Journal: Anticancer Res. 2007 Jul-Aug;27(4C):2931-7.
Title: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Author: Kiss, Istvan|Orsos, Zsuzsa|Gombos, Katalin|Bogner, Barna|Csejtei, Andras|Tibold, Antal|Varga, Zsuzsa|Pazsit, Emese|Magda, Ingrid|Zolyomi, Annamaria|Ember, Istvan
PMID: 17695473
Journal: Mutat Res. 2008 Sep 26;644(1-2):56-63.
Title: UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
Author: Girard, Hugo|Butler, Lesley M|Villeneuve, Lyne|Millikan, Robert C|Sinha, Rashmi|Sandler, Robert S|Guillemette, Chantal
PMID: 18675828
Journal: BMC Cancer. 2009 Nov 21;9:407.
Title: Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.
Author: Andersen, Vibeke|Ostergaard, Mette|Christensen, Jane|Overvad, Kim|Tjonneland, Anne|Vogel, Ulla
PMID: 19930591
Journal: Carcinogenesis. 2011 Feb;32(2):203-9.
Title: Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia.
Author: Wang, Hansong|Yamamoto, Jennifer F|Caberto, Christian|Saltzman, Barbara|Decker, Robert|Vogt, Thomas M|Yokochi, Lance|Chanock, Stephen|Wilkens, Lynne R|Le Marchand, Loic
PMID: 21081473
Journal: Toxicol In Vitro. 2011 Apr;25(3):671-83.
Title: Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2.
Author: Niestroy, Jeanette|Barbara, Alfonso|Herbst, Kathrin|Rode, Sandra|van Liempt, Manuela|Roos, Peter H
PMID: 21256954
Journal: PLoS One. 2013;8(3):e58591.
Title: Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis.
Author: Jamin, Emilien L|Riu, Anne|Douki, Thierry|Debrauwer, Laurent|Cravedi, Jean-Pierre|Zalko, Daniel|Audebert, Marc
PMID: 23484039