Primary Site >> Colorectal Cancer

Gene >> PAH

  • 1998
  • 1999
  • 2002
  • 2003
  • 2004
  • 2005
  • 2007
  • 2008
  • 2009
  • 2011
  • 2013
Ref: AH receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms.
PMID: 9762354
 Ref: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
PMID: 9973208
 Ref: Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
PMID: 12107646
 Ref: Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines.
PMID: 12655030
 Ref: Meat consumption patterns and preparation, genetic variants of metabolic enzymes, and their association with rectal cancer in men and women.
PMID: 15051825
 Ref: Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer.
PMID: 16030093
 Ref: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
PMID: 17695473
 Ref: UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
PMID: 18675828
 Ref: Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.
PMID: 19930591
 Ref: Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia.
PMID: 21081473
Ref: Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2.
PMID: 21256954
 Ref: Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis.
PMID: 23484039