Primary Site >> Colorectal Cancer

Gene >> NUMB

Journal: Nat Cell Biol. 2011 Aug 14;13(10):1244-51.
Title: Notch post-translationally regulates beta-catenin protein in stem and progenitor cells.
Author: Kwon, Chulan|Cheng, Paul|King, Isabelle N|Andersen, Peter|Shenje, Lincoln|Nigam, Vishal|Srivastava, Deepak
PMID: 21841793
Journal: Mol Cell Biol. 2011 Jan;31(1):138-50.
Title: Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer.
Author: Misquitta-Ali, Christine M|Cheng, Edith|O'Hanlon, Dave|Liu, Ni|McGlade, C Jane|Tsao, Ming Sound|Blencowe, Benjamin J
PMID: 21041478
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Jan;43(1):6-8, 14.
Title: [Numb expression in colon cancer and its significance].
Author: Zeng, Yun-Lin|Shao, Xi-Meng|Li, Hua-Shun
PMID: 22455121
Journal: Gastroenterology. 2013 Oct;145(4):820-30.e10.
Title: Progastrin stimulates colonic cell proliferation via CCK2R- and beta-arrestin-dependent suppression of BMP2.
Author: Jin, Guangchun|Westphalen, C Benedikt|Hayakawa, Yoku|Worthley, Daniel L|Asfaha, Samuel|Yang, Xiangdong|Chen, Xiaowei|Si, Yiling|Wang, Hongshan|Tailor, Yagnesh|Friedman, Richard A|Wang, Timothy C
PMID: 23891976
Journal: Cancer Res. 2014 Apr 1;74(7):2106-18.
Title: NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.
Author: Pasto, Anna|Serafin, Valentina|Pilotto, Giorgia|Lago, Claudia|Bellio, Chiara|Trusolino, Livio|Bertotti, Andrea|Hoey, Timothy|Plateroti, Michelina|Esposito, Giovanni|Pinazza, Marica|Agostini, Marco|Nitti, Donato|Amadori, Alberto|Indraccolo, Stefano
PMID: 24525742
Journal: Nat Cell Biol. 2014 Mar;16(3):268-80.
Title: MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.
Author: Hwang, Wei-Lun|Jiang, Jeng-Kae|Yang, Shung-Haur|Huang, Tse-Shun|Lan, Hsin-Yi|Teng, Hao-Wei|Yang, Chih-Yung|Tsai, Ya-Ping|Lin, Chi-Hung|Wang, Hsei-Wei|Yang, Muh-Hwa
PMID: 24561623
Journal: Nat Cell Biol. 2014 Mar;16(3):212-4.
Title: A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions.
Author: Lerner, Robin G|Petritsch, Claudia
PMID: 24576899
Journal: Oncotarget. 2014 May 30;5(10):3234-45.
Title: HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.
Author: Puca, Francesca|Colamaio, Marianna|Federico, Antonella|Gemei, Marica|Tosti, Nadia|Bastos, Andre Uchimura|Del Vecchio, Luigi|Pece, Salvatore|Battista, Sabrina|Fusco, Alfredo
PMID: 24833610
Journal: World J Gastroenterol. 2015 Jun 7;21(21):6550-60.
Title: Alternative splicing of VEGFA, APP and NUMB genes in colorectal cancer.
Author: Zhao, Yi-Jun|Han, Hua-Zhong|Liang, Yong|Shi, Chen-Zhang|Zhu, Qing-Chao|Yang, Jun
PMID: 26074693
Journal: Mol Oncol. 2015 Aug;9(7):1406-20.
Title: Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Author: Lan, Lan|Appelman, Carl|Smith, Amber R|Yu, Jia|Larsen, Sarah|Marquez, Rebecca T|Liu, Hao|Wu, Xiaoqing|Gao, Philip|Roy, Anuradha|Anbanandam, Asokan|Gowthaman, Ragul|Karanicolas, John|De Guzman, Roberto N|Rogers, Steven|Aube, Jeffrey|Ji, Min|Cohen, Robert S
PMID: 25933687
Journal: Cell Stem Cell. 2016 Feb 4;18(2):189-202.
Title: A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.
Author: Bu, Pengcheng|Wang, Lihua|Chen, Kai-Yuan|Srinivasan, Tara|Murthy, Preetish Kadur Lakshminarasimha|Tung, Kuei-Ling|Varanko, Anastasia Kristine|Chen, Huanhuan Joyce|Ai, Yiwei|King, Sarah|Lipkin, Steven M|Shen, Xiling
PMID: 26849305
Journal: Genome Res. 2016 Apr;26(4):541-53.
Title: A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1.
Author: Hollander, Dror|Donyo, Maya|Atias, Nir|Mekahel, Keren|Melamed, Zeev|Yannai, Sivan|Lev-Maor, Galit|Shilo, Asaf|Schwartz, Schraga|Barshack, Iris|Sharan, Roded|Ast, Gil
PMID: 26860615
Journal: Cell Cycle. 2016 Oct 17;15(20):2697-703.
Title: Numb is involved in the non-random segregation of subcellular vesicles in colorectal cancer stem cells.
Author: Hwang, Wei-Lun|Yang, Muh-Hwa
PMID: 27580100
Journal: Mol Cell Oncol. 2016 May 19;3(4):e1164279.
Title: Asymmetric division: An antitumor player?
Author: Wang, Lihua|Bu, Pengcheng|Shen, Xiling
PMID: 27652318
Journal: PLoS One. 2016 Nov 8;11(11):e0165912.
Title: miR-146a Polymorphism (rs2910164) Predicts Colorectal Cancer Patients' Susceptibility to Liver Metastasis.
Author: Iguchi, Tomohiro|Nambara, Sho|Masuda, Takaaki|Komatsu, Hisateru|Ueda, Masami|Kidogami, Shinya|Ogawa, Yushi|Hu, Qingjiang|Sato, Kuniaki|Saito, Tomoko|Hirata, Hidenari|Sakimura, Shotaro|Uchi, Ryutaro|Hayashi, Naoki|Ito, Shuhei|Eguchi, Hidetoshi|Sugimachi, K
PMID: 27824903
Journal: J Formos Med Assoc. 2017 Nov;116(11):897-906.
Title: Numb chin with mandibular pain or masticatory weakness as indicator for systemic malignancy - A case series study.
Author: Lu, Shin-Yu|Huang, Shu-Hua|Chen, Yen-Hao
PMID: 28728749
Journal: PLoS One. 2017 Nov 30;12(11):e0188665.
Title: Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma.
Author: Ma, Lin|Wang, Lan|Shan, Yating|Nafees, Muhammad|Ihab, Elshoura|Zhang, Ruhui|Wang, Fangjun|Yin, Wu
PMID: 29190716
Journal: BMC Cancer. 2018 Aug 10;18(1):809.
Title: Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins.
Author: Lan, Lan|Liu, Hao|Smith, Amber R|Appelman, Carl|Yu, Jia|Larsen, Sarah|Marquez, Rebecca T|Wu, Xiaoqing|Liu, Frank Y|Gao, Philip|Gowthaman, Ragul|Karanicolas, John|De Guzman, Roberto N|Rogers, Steven|Aube, Jeffrey|Neufeld, Kristi L|Xu, Liang
PMID: 30097032
Journal: Br J Cancer. 2018 Sep 17. pii: 10.1038/s41416-018-0254-z.
Title: Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p.
Author: Li, Hongdan|Li, Feng
PMID: 30220706