Primary Site >> Colorectal Cancer

Gene >> NUMB

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Ref: Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer.
PMID: 21041478
Ref: Notch post-translationally regulates beta-catenin protein in stem and progenitor cells.
PMID: 21841793
Ref: [Numb expression in colon cancer and its significance].
PMID: 22455121
Ref: Progastrin stimulates colonic cell proliferation via CCK2R- and beta-arrestin-dependent suppression of BMP2.
PMID: 23891976
Ref: NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.
PMID: 24525742
Ref: MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.
PMID: 24561623
Ref: A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions.
PMID: 24576899
Ref: HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.
PMID: 24833610
Ref: Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
PMID: 25933687
Ref: Alternative splicing of VEGFA, APP and NUMB genes in colorectal cancer.
PMID: 26074693
Ref: A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.
PMID: 26849305
Ref: A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1.
PMID: 26860615
Ref: Numb is involved in the non-random segregation of subcellular vesicles in colorectal cancer stem cells.
PMID: 27580100
Ref: Asymmetric division: An antitumor player?
PMID: 27652318
Ref: miR-146a Polymorphism (rs2910164) Predicts Colorectal Cancer Patients' Susceptibility to Liver Metastasis.
PMID: 27824903
Ref: Numb chin with mandibular pain or masticatory weakness as indicator for systemic malignancy - A case series study.
PMID: 28728749
Ref: Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma.
PMID: 29190716
Ref: Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins.
PMID: 30097032
Ref: Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p.
PMID: 30220706