Primary Site >> Colorectal Cancer

Gene >> NUDT1

Journal: Biochem Biophys Res Commun. 1995 Sep 25;214(3):1239-45.
Title: Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer.
Author: Wu, C|Nagasaki, H|Maruyama, K|Nakabeppu, Y|Sekiguchi, M|Yuasa, Y
PMID: 7575536
Journal: Int J Oncol. 2000 Sep;17(3):467-71.
Title: Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer.
Author: Takama, F|Kanuma, T|Wang, D|Nishida, J I|Nakabeppu, Y|Wake, N|Mizunuma, H
PMID: 10938385
Journal: Am J Pathol. 2003 May;162(5):1545-8.
Title: Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
Author: Halford, Sarah E R|Rowan, Andrew J|Lipton, Lara|Sieber, Oliver M|Pack, Kevin|Thomas, Huw J W|Hodgson, Shirley V|Bodmer, Walter F|Tomlinson, Ian P M
PMID: 12707038
Journal: Hepatogastroenterology. 2004 May-Jun;51(57):638-42.
Title: Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer.
Author: Koketsu, Shinichiro|Watanabe, Toshiaki|Nagawa, Hirokazu
PMID: 15143881
Journal: Hum Genet. 2004 Nov;115(6):498-503. Epub 2004 Sep 24.
Title: Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients.
Author: Kim, I-J|Ku, J-L|Kang, H C|Park, J-H|Yoon, K-A|Shin, Y|Park, H-W|Jang, S G|Lim, S-K|Han, S Y|Shin, Y-K|Lee, M R|Jeong, S-Y|Shin, H-R|Lee, J S|Kim, W-H|Park, J-G
PMID: 15449173
Journal: Am J Hum Genet. 2005 Jul;77(1):112-9. Epub 2005 May 3.
Title: Germline susceptibility to colorectal cancer due to base-excision repair gene defects.
Author: Farrington, Susan M|Tenesa, Albert|Barnetson, Rebecca|Wiltshire, Alice|Prendergast, James|Porteous, Mary|Campbell, Harry|Dunlop, Malcolm G
PMID: 15931596
Journal: Int J Cancer. 2007 Aug 1;121(3):555-8.
Title: Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.
Author: Schafmayer, Clemens|Buch, Stephan|Egberts, Jan Hendrik|Franke, Andre|Brosch, Mario|El Sharawy, Abdou|Conring, Mareike|Koschnick, Maralde|Schwiedernoch, Sven|Katalinic, Alexander|Kremer, Bernd|Folsch, Ulrich R|Krawczak, Michael|Fandrich, Fred|Schreiber, St
PMID: 17417778
Journal: Genet Med. 2007 Dec;9(12):836-41.
Title: Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
Author: Cattaneo, Francesca|Molatore, Sara|Mihalatos, Markos|Apessos, Angela|Venesio, Tiziana|Bione, Silvia|Grignani, Pierangela|Nasioulas, Georgios|Ranzani, Guglielmina Nadia
PMID: 18091433
Journal: Gut. 2008 Sep;57(9):1252-5.
Title: Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3.
Author: Dallosso, A R|Dolwani, S|Jones, N|Jones, S|Colley, J|Maynard, J|Idziaszczyk, S|Humphreys, V|Arnold, J|Donaldson, A|Eccles, D|Ellis, A|Evans, D G|Frayling, I M|Hes, F J|Houlston, R S|Maher, E R|Nielsen, M|Parry, S|Tyler, E|Moskvina, V|Cheadle, J P|Sampson,
PMID: 18515411
Journal: Mutagenesis. 2010 Sep;25(5):463-71.
Title: Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients.
Author: Obtulowicz, Tomasz|Swoboda, Maja|Speina, Elzbieta|Gackowski, Daniel|Rozalski, Rafal|Siomek, Agnieszka|Janik, Justyna|Janowska, Beata|Ciesla, Jaroslaw M|Jawien, Arkadiusz|Banaszkiewicz, Zbigniew|Guz, Jolanta|Dziaman, Tomasz|Szpila, Anna|Olinski, Ryszard|Tu
PMID: 20534734
Journal: Eur J Cancer. 2011 May;47(7):1046-55.
Title: First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes.
Author: Morak, Monika|Massdorf, Trisari|Sykora, Helena|Kerscher, Martina|Holinski-Feder, Elke
PMID: 21195604
Journal: Clin Cancer Res. 2011 Apr 1;17(7):1701-12.
Title: Analysis of the oxidative damage repair genes NUDT1, OGG1, and MUTYH in patients from mismatch repair proficient HNPCC families (MSS-HNPCC).
Author: Garre, Pilar|Briceno, Veronica|Xicola, Rosa M|Doyle, Brian J|de la Hoya, Miguel|Sanz, Julian|Llovet, Patricia|Pescador, Paula|Puente, Javier|Diaz-Rubio, Eduardo|Llor, Xavier|Caldes, Trinidad
PMID: 21355073
Journal: Nature. 2014 Apr 10;508(7495):222-7.
Title: Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Author: Huber, Kilian V M|Salah, Eidarus|Radic, Branka|Gridling, Manuela|Elkins, Jonathan M|Stukalov, Alexey|Jemth, Ann-Sofie|Gokturk, Camilla|Sanjiv, Kumar|Stromberg, Kia|Pham, Therese|Berglund, Ulrika Warpman|Colinge, Jacques|Bennett, Keiryn L|Loizou, Joanna I|
PMID: 24695225
Journal: World J Gastroenterol. 2015 Dec 28;21(48):13447-56.
Title: Hypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer.
Author: Qiu, Yuan|Zheng, Hong|Sun, Li-Hua|Peng, Ke|Xiao, Wei-Dong|Yang, Hua
PMID: 26730155
Journal: J Am Chem Soc. 2016 Jul 27;138(29):9005-8.
Title: A Chimeric ATP-Linked Nucleotide Enables Luminescence Signaling of Damage Surveillance by MTH1, a Cancer Target.
Author: Ji, Debin|Beharry, Andrew A|Ford, James M|Kool, Eric T
PMID: 27413803
Journal: Oncotarget. 2017 Nov 11;8(62):105714-105726.
Title: MutT-related proteins are novel progression and prognostic markers for colorectal cancer.
Author: Li, Jin|Yang, Cheng-Cheng|Tian, Xin-Yuan|Li, Yun-Xuan|Cui, Ju|Chen, Zhe|Deng, Zhou-Lu|Chen, Fu-Jun|Hayakawa, Hiroshi|Sekiguchi, Mutsuo|Cai, Jian-Ping
PMID: 29285286
Journal: Mol Genet Genomic Med. 2018 Apr 17.
Title: Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.
Author: Kamiza, Abram B|Hsieh, Ling-Ling|Tang, Reiping|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|You, Jeng-Fu|Wang, Wen-Chang|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 29664240
Journal: Genes Dev. 2018 May 1;32(9-10):597-599.
Title: Telomerase can't handle the stress.
Author: Smith, Susan
PMID: 29802121
Journal: Hum Mutat. 2018 Sep;39(9):1214-1225.
Title: Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis.
Author: Mur, Pilar|Jemth, Ann-Sofie|Bevc, Luka|Amaral, Nuno|Navarro, Matilde|Valdes-Mas, Rafael|Pons, Tirso|Aiza, Gemma|Urioste, Miguel|Valencia, Alfonso|Lazaro, Conxi|Moreno, Victor|Puente, Xose S|Stenmark, Pal|Warpman-Berglund, Ulrika|Capella, Gabriel|Helleday,
PMID: 29900613