Primary Site >> Colorectal Cancer
Gene >> NUDT1
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Ref: Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer. PMID: 7575536 |
Ref: Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer. PMID: 10938385 |
Ref: Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. PMID: 12707038 |
Ref: Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer. PMID: 15143881 Ref: Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients. PMID: 15449173 |
Ref: Germline susceptibility to colorectal cancer due to base-excision repair gene defects. PMID: 15931596 |
Ref: Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer. PMID: 17417778 Ref: Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis. PMID: 18091433 |
Ref: Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3. PMID: 18515411 |
Ref: Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. PMID: 20534734 |
Ref: First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes. PMID: 21195604 Ref: Analysis of the oxidative damage repair genes NUDT1, OGG1, and MUTYH in patients from mismatch repair proficient HNPCC families (MSS-HNPCC). PMID: 21355073 |
Ref: Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. PMID: 24695225 |
Ref: Hypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer. PMID: 26730155 |
Ref: A Chimeric ATP-Linked Nucleotide Enables Luminescence Signaling of Damage Surveillance by MTH1, a Cancer Target. PMID: 27413803 |
Ref: MutT-related proteins are novel progression and prognostic markers for colorectal cancer. PMID: 29285286 |
Ref: Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome. PMID: 29664240 Ref: Telomerase can't handle the stress. PMID: 29802121 Ref: Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis. PMID: 29900613 |