Primary Site >> Colorectal Cancer

Gene >> NTRK2

Journal: Princess Takamatsu Symp. 1991;22:153-70.
Title: The trk family of oncogenes and neurotrophin receptors.
Author: Lamballe, F|Klein, R|Barbacid, M
PMID: 1844238
Journal: Oncogene. 2007 Mar 29;26(14):2133-5. Epub 2006 Oct 2.
Title: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.
Author: Shao, R-X|Kato, N|Lin, L-J|Muroyama, R|Moriyama, M|Ikenoue, T|Watabe, H|Otsuka, M|Guleng, B|Ohta, M|Tanaka, Y|Kondo, S|Dharel, N|Chang, J-H|Yoshida, H|Kawabe, T|Omata, M
PMID: 17016444
Journal: J Neurochem. 2008 Oct;107(2):398-417.
Title: Depolarization recruits DCC to the plasma membrane of embryonic cortical neurons and enhances axon extension in response to netrin-1.
Author: Bouchard, Jean-Francois|Horn, Katherine E|Stroh, Thomas|Kennedy, Timothy E
PMID: 18691385
Journal: APMIS. 2010 Mar;118(3):188-95.
Title: Overexpression of TrkB promotes the progression of colon cancer.
Author: Yu, Yingjiao|Zhang, Siyang|Wang, Xuemei|Yang, Zhiwei|Ou, Guocheng
PMID: 20132184
Journal: Oncology. 2010;79(5-6):430-9.
Title: BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer.
Author: Brunetto de Farias, Caroline|Rosemberg, Denis Broock|Heinen, Tiago Elias|Koehler-Santos, Patricia|Abujamra, Ana Lucia|Kapczinski, Flavio|Brunetto, Algemir Lunardi|Ashton-Prolla, Patricia|Meurer, Luise|Reis Bogo, Mauricio|Damin, Daniel C|Schwartsmann, Gilb
PMID: 21474968
Journal: PLoS One. 2011 Feb 17;6(2):e16871.
Title: Functional characterization of human cancer-derived TRKB mutations.
Author: Geiger, Thomas R|Song, Ji-Ying|Rosado, Aranzazu|Peeper, Daniel S
PMID: 21379385
Journal: PLoS One. 2011;6(9):e25097.
Title: Fine-tuning roles of endogenous brain-derived neurotrophic factor, TrkB and sortilin in colorectal cancer cell survival.
Author: Akil, Hussein|Perraud, Aurelie|Melin, Carole|Jauberteau, Marie-Odile|Mathonnet, Muriel
PMID: 21966426
Journal: Biochem Biophys Res Commun. 2012 Aug 24;425(2):328-32. Epub 2012 Jul 25.
Title: BDNF/TrkB signaling protects HT-29 human colon cancer cells from EGFR inhibition.
Author: de Farias, Caroline Brunetto|Heinen, Tiago Elias|dos Santos, Rafael Pereira|Abujamra, Ana Lucia|Schwartsmann, Gilberto|Roesler, Rafael
PMID: 22842573
Journal: Clin Transl Gastroenterol. 2012 Dec 6;3:e27.
Title: A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors.
Author: Ahmed, Deeqa|Danielsen, Stine A|Aagesen, Trude H|Bretthauer, Michael|Thiis-Evensen, Espen|Hoff, Geir|Rognum, Torleiv O|Nesbakken, Arild|Lothe, Ragnhild A|Lind, Guro E
PMID: 23324654
Journal: Hum Pathol. 2013 Jun;44(6):1098-106.
Title: Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma.
Author: Sasahira, Tomonori|Ueda, Nobuhiro|Kurihara, Miyako|Matsushima, Sayako|Ohmori, Hitoshi|Fujii, Kiyomu|Bhawal, Ujjal K|Yamamoto, Kazuhiko|Kirita, Tadaaki|Kuniyasu, Hiroki
PMID: 23332094
Journal: Apoptosis. 2014 May;19(5):860-70.
Title: Tropomyosin-related kinase B promotes distant metastasis of colorectal cancer through protein kinase B-mediated anoikis suppression and correlates with poor prognosis.
Author: Fan, Meng|Sun, Jianyong|Wang, Wei|Fan, Jing|Wang, Lei|Zhang, Xiang|Yang, Angang|Wang, Weizhong|Zhang, Rui|Li, Jipeng
PMID: 24549576
Journal: PLoS One. 2014 May 6;9(5):e96410.
Title: Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer.
Author: Tanaka, Koji|Okugawa, Yoshinaga|Toiyama, Yuji|Inoue, Yasuhiro|Saigusa, Susumu|Kawamura, Mikio|Araki, Toshimitsu|Uchida, Keiichi|Mohri, Yasuhiko|Kusunoki, Masato
PMID: 24801982
Journal: Mol Clin Oncol. 2014 Sep;2(5):725-730.
Title: Investigation of neurotrophic tyrosine kinase receptor 1 fusions and neurotrophic tyrosine kinase receptor family expression in non-small-cell lung cancer and sensitivity to AZD7451 in vitro.
Author: Tatematsu, Tsutomu|Sasaki, Hidefumi|Shimizu, Shigeki|Okuda, Katsuhiro|Shitara, Masayuki|Hikosaka, Yu|Moriyama, Satoru|Yano, Motoki|Brown, Jeffrey|Fujii, Yoshitaka
PMID: 25054037
Journal: Histopathology. 2015 Apr;66(5):715-25.
Title: Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells.
Author: Dawson, Heather|Grundmann, Sandra|Koelzer, Viktor H|Galvan, Jose A|Kirsch, Richard|Karamitopoulou, Eva|Lugli, Alessandro|Inderbitzin, Daniel|Zlobec, Inti
PMID: 25382057
Journal: World J Gastroenterol. 2016 Jan 14;22(2):490-500.
Title: Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancer.
Author: Akil, Hussein|Perraud, Aurelie|Jauberteau, Marie-Odile|Mathonnet, Muriel
PMID: 26811602
Journal: Pharmacol Ther. 2017 May;173:58-66.
Title: Targeting TRK family proteins in cancer.
Author: Khotskaya, Yekaterina B|Holla, Vijaykumar R|Farago, Anna F|Mills Shaw, Kenna R|Meric-Bernstam, Funda|Hong, David S
PMID: 28174090
Journal: Oncotarget. 2017 Jun 20;8(25):39945-39962.
Title: BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
Author: Deihimi, Safoora|Lev, Avital|Slifker, Michael|Shagisultanova, Elena|Xu, Qifang|Jung, Kyungsuk|Vijayvergia, Namrata|Ross, Eric A|Xiu, Joanne|Swensen, Jeffrey|Gatalica, Zoran|Andrake, Mark|Dunbrack, Roland L|El-Deiry, Wafik S
PMID: 28591715
Journal: J Cell Mol Med. 2017 Oct;21(10):2610-2622.
Title: Dual inhibition of BDNF/TrkB and autophagy: a promising therapeutic approach for colorectal cancer.
Author: Mazouffre, Clement|Geyl, Sophie|Perraud, Aurelie|Blondy, Sabrina|Jauberteau, Marie-Odile|Mathonnet, Muriel|Verdier, Mireille
PMID: 28597984
Journal: Tumour Biol. 2017 Jul;39(7):1010428317714899.
Title: Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing.
Author: Liu, Jixi|Liu, Fang|Li, Xiaoou|Song, Xin|Zhou, Lei|Jie, Jianzheng
PMID: 28714374