Primary Site >> Pancreatic Cancer

Gene >> NTRK1

Journal: Diabetes. 1993 Dec;42(12):1829-36.
Title: Expression of functional nerve growth factor receptors in pancreatic beta-cell lines and fetal rat islets in primary culture.
Author: Scharfmann, R|Tazi, A|Polak, M|Kanaka, C|Czernichow, P
PMID: 8243829
Journal: Crit Rev Oncog. 1996;7(1-2):89-100.
Title: Neurotrophin-Trk receptor interactions in neoplasia: a possible role in interstitial and perineural invasion in ductal pancreatic cancer.
Author: Miknyoczki, S J|Klein-Szanto, A J|Ruggeri, B A
PMID: 9109499
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:252-62.
Title: The novel Trk receptor tyrosine kinase inhibitor CEP-701 (KT-5555) exhibits antitumor efficacy against human pancreatic carcinoma (Panc1) xenograft growth and in vivo invasiveness.
Author: Miknyoczki, S J|Dionne, C A|Klein-Szanto, A J|Ruggeri, B A
PMID: 10415871
Journal: J Clin Oncol. 1999 Aug;17(8):2419-28.
Title: Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer.
Author: Zhu, Z|Friess, H|diMola, F F|Zimmermann, A|Graber, H U|Korc, M|Buchler, M W
PMID: 10561305
Journal: Clin Cancer Res. 2001 Jan;7(1):105-12.
Title: Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
Author: Zhu, Z W|Friess, H|Wang, L|Bogardus, T|Korc, M|Kleeff, J|Buchler, M W
PMID: 11205897
Journal: J Histochem Cytochem. 2001 Oct;49(10):1205-10.
Title: Expression of nerve growth factors in pancreatic neural tissue and pancreatic cancer.
Author: Schneider, M B|Standop, J|Ulrich, A|Wittel, U|Friess, H|Andren-Sandberg, A|Pour, P M
PMID: 11561004
Journal: Int J Mol Med. 2002 May;9(5):509-13.
Title: Expression of human GIPC1 in normal tissues, cancer cell lines, and primary tumors.
Author: Kirikoshi, Hiroyuki|Katoh, Masaru
PMID: 11956658
Journal: Clin Cancer Res. 2002 Jun;8(6):1924-31.
Title: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice.
Author: Miknyoczki, Sheila J|Wan, Weihua|Chang, Hong|Dobrzanski, Pawel|Ruggeri, Bruce A|Dionne, Craig A|Buchkovich, Karen
PMID: 12060637
Journal: Clin Exp Metastasis. 2004;21(4):285-92.
Title: Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells.
Author: Okada, Yuji|Eibl, Guido|Guha, Sushovan|Duffy, John P|Reber, Howard A|Hines, Oscar J
PMID: 15554384
Journal: Oncogene. 2005 Jul 28;24(32):5108-18.
Title: Methylation adjacent to negatively regulating AP-1 site reactivates TrkA gene expression during cancer progression.
Author: Fujimoto, Masayo|Kitazawa, Riko|Maeda, Sakan|Kitazawa, Sohei
PMID: 15870692
Journal: Oncol Rep. 2005 Jul;14(1):161-71.
Title: Expression of nerve growth factor receptors and their prognostic value in human pancreatic cancer.
Author: Zhang, Yong|Dang, Chengxue|Ma, Qingyong|Shimahara, Yasuyuki
PMID: 15944784
Journal: J Gastroenterol Hepatol. 2006 May;21(5):850-8.
Title: Expression of nerve growth factor receptors is correlated with progression and prognosis of human pancreatic cancer.
Author: Dang, Chengxue|Zhang, Yong|Ma, Qingyong|Shimahara, Yasuyuki
PMID: 16704535
Journal: Oncol Rep. 2007 Sep;18(3):673-7.
Title: siRNA directed against TrkA sensitizes human pancreatic cancer cells to apoptosis induced by gemcitabine through an inactivation of PI3K/Akt-dependent pathway.
Author: Liu, Dapeng|Zhang, Yong|Dang, Chengxue|Ma, Qingyong|Lee, Woo|Chen, Wuke
PMID: 17671718
Journal: Invest New Drugs. 2008 Jun;26(3):241-7.
Title: A phase I trial of CEP-701 + gemcitabine in patients with advanced adenocarcinoma of the pancreas.
Author: Chan, Emily|Mulkerin, Daniel|Rothenberg, Mace|Holen, Kyle D|Lockhart, A Craig|Thomas, James|Berlin, Jordan
PMID: 18217204
Journal: J Gastroenterol Hepatol. 2008 Dec;23(12):1852-9.
Title: Expression of nerve growth factor and tyrosine kinase receptor A and correlation with perineural invasion in pancreatic cancer.
Author: Ma, Jun|Jiang, Yumei|Jiang, Yuhua|Sun, Yan|Zhao, Xueming
PMID: 19120874
Journal: Zhonghua Nei Ke Za Zhi. 2009 Jul;48(7):562-5.
Title: [The expression and significance of nerve growth factor and its receptors in pancreatic ductal adenocarcinoma].
Author: Meng, Ling-Xin|Ding, Zhao-Jun|Chen, Xi-Ping|Fei, Li-Sheng|Chi, Yu-Hua|Zhao, Zhi-Gang|Wang, Xiao-Fang|Hao, Xi-Shan
PMID: 19957796
Journal: J Oral Maxillofac Surg. 2010 Jun;68(6):1290-5.
Title: Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion?
Author: Kolokythas, Antonia|Cox, Darren P|Dekker, Nusi|Schmidt, Brian L
PMID: 20363547
Journal: Mol Med Rep. 2010 Jan-Feb;3(1):103-9.
Title: Nerve growth factor and receptors are significantly affected by histamine stimulus through H1 receptor in pancreatic carcinoma cells.
Author: Wang, Zhi-Yu|Ding, Yan|Miki, Takanori|Warita, Katsuhiko|Matsumoto, Yoshiki|Takeuchi, Yoshiki|Wang, Shi-Jie|Feng, Jian-Gang|Liu, Wei|Wang, Ya-Di|Wang, Xiao-Ling|Wang, Yu-Hua|Liu, Ya|Shan, Bao-En
PMID: 21472207
Journal: PLoS One. 2011 Feb 28;6(2):e17385.
Title: Relationship between neural alteration and perineural invasion in pancreatic cancer patients with hyperglycemia.
Author: Li, Junhui|Ma, Qingyong|Liu, Han|Guo, Kun|Li, Feng|Li, Wei|Han, Liang|Wang, Fengfei|Wu, Erxi
PMID: 21386984
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2012 Mar;32(3):296-300.
Title: [Responses of pancreatic cancer cells to stimulations by nerve growth factor and the role of Trk-A expression].
Author: Diao, Dong-Mei|Song, Yong-Chun|Hou, Ni|Xu, Hai-Fei|Wang, Jian-Guang|Dang, Cheng-Xue
PMID: 22445970
Journal: Int J Med Sci. 2013;10(5):634-40.
Title: Proliferation enhanced by NGF-NTRK1 signaling makes pancreatic cancer cells more sensitive to 2DG-induced apoptosis.
Author: Cheng, Yao|Diao, Dong-mei|Zhang, Hao|Song, Yong-Chun|Dang, Cheng-Xue
PMID: 23569426
Journal: Cancer Lett. 2013 Sep 28;338(2):271-81.
Title: Anti-cancer effect of HS-345, a new tropomyosin-related kinase A inhibitor, on human pancreatic cancer.
Author: Seo, Ju Hyeon|Jung, Kyung Hee|Son, Mi Kwon|Yan, Hong Hua|Ryu, Ye-Lim|Kim, Jinhee|Lee, Jung Kyun|Hong, Sungwoo|Hong, Soon-Sun
PMID: 23587795
Journal: Exp Mol Med. 2013 Jun 7;45:e26.
Title: Functional proteomics, human genetics and cancer biology of GIPC family members.
Author: Katoh, Masaru
PMID: 23743496
Journal: Mol Cell Biol. 2016 Sep 26;36(20):2596-611.
Title: Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
Author: Li, Chunhui|MacDonald, James I S|Talebian, Asghar|Leuenberger, Jennifer|Seah, Claudia|Pasternak, Stephen H|Michnick, Stephen W|Meakin, Susan O
PMID: 27503856
Journal: PLoS One. 2016 Oct 28;11(10):e0165586.
Title: Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells.
Author: Bapat, Aditi A|Munoz, Ruben M|Von Hoff, Daniel D|Han, Haiyong
PMID: 27792755
Journal: J Gene Med. 2017 Jan;19(1-2).
Title: MicroRNA-4656 is a prognostic factor and tumor suppressor in human pancreatic cancer through a downstream target of TrkA.
Author: Tan, Xianglong|Lv, Jinyong|Zhao, Guodong|Zhao, Zhiming|Li, Chenggang|Xu, Yong|Hu, Minggen
PMID: 27936486
Journal: Tumour Biol. 2017 Feb;39(2):1010428317692256.
Title: The significance of Trk receptors in pancreatic cancer.
Author: Johnson, Matthew D|Stone, Brandon|Thibodeau, Bryan J|Baschnagel, Andrew M|Galoforo, Sandra|Fortier, Laura E|Ketelsen, Billie|Ahmed, Samreen|Kelley, Zakiya|Hana, Alaa|Wilson, Thomas G|Robertson, John M|Jury, Robert P|Wilson, George D
PMID: 28218045
Journal: Oncotarget. 2017 Jun 20;8(25):39945-39962.
Title: BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
Author: Deihimi, Safoora|Lev, Avital|Slifker, Michael|Shagisultanova, Elena|Xu, Qifang|Jung, Kyungsuk|Vijayvergia, Namrata|Ross, Eric A|Xiu, Joanne|Swensen, Jeffrey|Gatalica, Zoran|Andrake, Mark|Dunbrack, Roland L|El-Deiry, Wafik S
PMID: 28591715
Journal: J Gene Med. 2017 Jun;19(6-7).
Title: Retraction: 'MicroRNA-4656 is a prognostic factor and tumor suppressor in human pancreatic cancer through a downstream target of TrkA' by Xianglong Tan, Jinyong Lv, Guodong Zhao, Zhiming Zhao, Chenggang Li, Yong Xu and Minggen Hu.
Author:
PMID: 28749040
Journal: Cancer Cell. 2018 Jan 8;33(1):75-90.e7.
Title: beta2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Author: Renz, Bernhard W|Takahashi, Ryota|Tanaka, Takayuki|Macchini, Marina|Hayakawa, Yoku|Dantes, Zahra|Maurer, H Carlo|Chen, Xiaowei|Jiang, Zhengyu|Westphalen, C Benedikt|Ilmer, Matthias|Valenti, Giovanni|Mohanta, Sarajo K|Habenicht, Andreas J R|Middelhoff, Mor
PMID: 29249692
Journal: Cancer Lett. 2018 Jul 10;426:25-36.
Title: A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer.
Author: Fang, Zhenghuan|Han, Boreum|Jung, Kyung Hee|Lee, Ju-Hyeon|El-Damasy, Ashraf Kareem|Gadhe, Changdev G|Kim, Soo Jung|Yan, Hong Hua|Park, Jung Hee|Lee, Ji Eun|Kang, Yeo Wool|Pae, Ae Nim|Keum, Gyochang|Hong, Soon-Sun
PMID: 29605512
Journal: Curr Treat Options Oncol. 2018 Aug 20;19(10):48.
Title: Harnessing the Immune System in Pancreatic Cancer.
Author: Das, Satya|Berlin, Jordan|Cardin, Dana
PMID: 30128712