Primary Site >> Pancreatic Cancer

Gene >> NTRK1

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Ref: Expression of functional nerve growth factor receptors in pancreatic beta-cell lines and fetal rat islets in primary culture.
PMID: 8243829
Ref: Neurotrophin-Trk receptor interactions in neoplasia: a possible role in interstitial and perineural invasion in ductal pancreatic cancer.
PMID: 9109499
Ref: The novel Trk receptor tyrosine kinase inhibitor CEP-701 (KT-5555) exhibits antitumor efficacy against human pancreatic carcinoma (Panc1) xenograft growth and in vivo invasiveness.
PMID: 10415871
Ref: Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer.
PMID: 10561305
Ref: Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
PMID: 11205897
Ref: Expression of nerve growth factors in pancreatic neural tissue and pancreatic cancer.
PMID: 11561004
Ref: Expression of human GIPC1 in normal tissues, cancer cell lines, and primary tumors.
PMID: 11956658
Ref: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice.
PMID: 12060637
Ref: Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells.
PMID: 15554384
Ref: Methylation adjacent to negatively regulating AP-1 site reactivates TrkA gene expression during cancer progression.
PMID: 15870692
Ref: Expression of nerve growth factor receptors and their prognostic value in human pancreatic cancer.
PMID: 15944784
Ref: Expression of nerve growth factor receptors is correlated with progression and prognosis of human pancreatic cancer.
PMID: 16704535
Ref: siRNA directed against TrkA sensitizes human pancreatic cancer cells to apoptosis induced by gemcitabine through an inactivation of PI3K/Akt-dependent pathway.
PMID: 17671718
Ref: A phase I trial of CEP-701 + gemcitabine in patients with advanced adenocarcinoma of the pancreas.
PMID: 18217204
Ref: Expression of nerve growth factor and tyrosine kinase receptor A and correlation with perineural invasion in pancreatic cancer.
PMID: 19120874
Ref: [The expression and significance of nerve growth factor and its receptors in pancreatic ductal adenocarcinoma].
PMID: 19957796
Ref: Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion?
PMID: 20363547
Ref: Nerve growth factor and receptors are significantly affected by histamine stimulus through H1 receptor in pancreatic carcinoma cells.
PMID: 21472207
Ref: Relationship between neural alteration and perineural invasion in pancreatic cancer patients with hyperglycemia.
PMID: 21386984
Ref: [Responses of pancreatic cancer cells to stimulations by nerve growth factor and the role of Trk-A expression].
PMID: 22445970
Ref: Proliferation enhanced by NGF-NTRK1 signaling makes pancreatic cancer cells more sensitive to 2DG-induced apoptosis.
PMID: 23569426
Ref: Anti-cancer effect of HS-345, a new tropomyosin-related kinase A inhibitor, on human pancreatic cancer.
PMID: 23587795
Ref: Functional proteomics, human genetics and cancer biology of GIPC family members.
PMID: 23743496
Ref: Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
PMID: 27503856
Ref: Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells.
PMID: 27792755
Ref: MicroRNA-4656 is a prognostic factor and tumor suppressor in human pancreatic cancer through a downstream target of TrkA.
PMID: 27936486
Ref: The significance of Trk receptors in pancreatic cancer.
PMID: 28218045
Ref: BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
PMID: 28591715
Ref: Retraction: 'MicroRNA-4656 is a prognostic factor and tumor suppressor in human pancreatic cancer through a downstream target of TrkA' by Xianglong Tan, Jinyong Lv, Guodong Zhao, Zhiming Zhao, Chenggang Li, Yong Xu and Minggen Hu.
PMID: 28749040
Ref: beta2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
PMID: 29249692
Ref: A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer.
PMID: 29605512
Ref: Harnessing the Immune System in Pancreatic Cancer.
PMID: 30128712