Primary Site >> Colorectal Cancer

Gene >> NRP1

Journal: Am J Pathol. 2004 Jun;164(6):2139-51.
Title: Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis.
Author: Parikh, Alexander A|Fan, Fan|Liu, Wen Biao|Ahmad, Syed A|Stoeltzing, Oliver|Reinmuth, Niels|Bielenberg, Diane|Bucana, Corazon D|Klagsbrun, Michael|Ellis, Lee M
PMID: 15161648
Journal: Oncol Rep. 2006 Feb;15(2):369-73.
Title: The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer.
Author: Kamiya, Takashi|Kawakami, Tsutomu|Abe, Yoshiyuki|Nishi, Masatake|Onoda, Noboru|Miyazaki, Noriyuki|Oida, Yasuhisa|Yamazaki, Hitoshi|Ueyama, Yoshito|Nakamura, Masato
PMID: 16391856
Journal: Postepy Hig Med Dosw (Online). 2006;60:453-70.
Title: [Mechanisms of metastasis and molecular markers of malignant tumor progression. I. Colorectal cancer].
Author: Widel, Maciej S|Widel, Maria
PMID: 17013365
Journal: Pharmacogenomics. 2007 Dec;8(12):1705-13.
Title: Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients.
Author: Azuma, Mizutomo|Shi, Michael|Danenberg, Kathleen D|Gardner, Humphrey|Barrett, Carl|Jacques, Christian J|Sherod, Andrew|Iqbal, Syma|El-Khoueiry, Anthony|Yang, Dongyun|Zhang, Wu|Danenberg, Peter V|Lenz, Heinz-Josef
PMID: 18086000
Journal: Oncol Rep. 2009 May;21(5):1161-8.
Title: No functional and transductional significance of specific neuropilin 1 siRNA inhibition in colon carcinoma cell lines lacking VEGF receptor 2.
Author: Quante, Michael|Raskopf, Esther|Stahl, Sebastian|Vogt, Annabelle|Sauerbruch, Tilman|Schmitz, Volker
PMID: 19360289
Journal: Cancer Res. 2009 Oct 15;69(20):7905-10.
Title: Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer.
Author: Xu, Lei|Duda, Dan G|di Tomaso, Emmanuelle|Ancukiewicz, Marek|Chung, Daniel C|Lauwers, Gregory Y|Samuel, Rekha|Shellito, Paul|Czito, Brian G|Lin, Pei-Chun|Poleski, Martin|Bentley, Rex|Clark, Jeffrey W|Willett, Christopher G|Jain, Rakesh K
PMID: 19826039
Journal: J Clin Invest. 2010 Aug;120(8):2658-60.
Title: Semaphorin 3E, an exception to the rule.
Author: Klagsbrun, Michael|Shimizu, Akio
PMID: 20664165
Journal: Mol Cancer. 2010 Oct 15;9:276.
Title: Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation.
Author: Yu, Danny C W|Waby, Jennifer S|Chirakkal, Haridasan|Staton, Carolyn A|Corfe, Bernard M
PMID: 20950431
Journal: Anticancer Res. 2010 Oct;30(10):4209-17.
Title: Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study).
Author: Zhang, Wu|Azuma, Mizutomo|Lurje, Georg|Gordon, Michael A|Yang, Dongyun|Pohl, Alexandra|Ning, Yan|Bohanes, Pierre|Gerger, Armin|Winder, Thomas|Hollywood, Ellen|Danenberg, Kathleen D|Saltz, Leonard|Lenz, Heinz-Josef
PMID: 21036743
Journal: Mol Cancer. 2011 Mar 14;10:27.
Title: Short-chain fatty acid level and field cancerization show opposing associations with enteroendocrine cell number and neuropilin expression in patients with colorectal adenoma.
Author: Yu, Danny C W|Bury, Jonathan P|Tiernan, James|Waby, Jennifer S|Staton, Carolyn A|Corfe, Bernard M
PMID: 21401950
Journal: PLoS One. 2011 Apr 4;6(4):e18306.
Title: NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.
Author: Savas, Sevtap|Azorsa, David O|Jarjanazi, Hamdi|Ibrahim-Zada, Irada|Gonzales, Irma M|Arora, Shilpi|Henderson, Meredith C|Choi, Yun Hee|Briollais, Laurent|Ozcelik, Hilmi|Tuzmen, Sukru
PMID: 21483694
Journal: Oncol Rep. 2012 Mar;27(3):685-94.
Title: microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer.
Author: Zhang, Yujun|He, Xiangjun|Liu, Yulan|Ye, Yingjiang|Zhang, Hui|He, Peiying|Zhang, Qi|Dong, Lingyi|Liu, Yujing|Dong, Jianqiang
PMID: 22134529
Journal: J Transl Med. 2012 Dec 24;10:254.
Title: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo.
Author: Fan, Chung-Wei|Chen, Chun-Yu|Chen, Kuei-Tien|Shen, Chia-Rui|Kuo, Yung-Bin|Chen, Ya-Shan|Chou, Yeh-Pin|Wei, Wei-Shan|Chan, Err-Cheng
PMID: 23259795
Journal: Br J Cancer. 2013 Nov 26;109(11):2765-73.
Title: Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy.
Author: Spencer, S K M|Pommier, A J C|Morgan, S R|Barry, S T|Robertson, J D|Hoff, P M|Jurgensmeier, J M
PMID: 24149180
Journal: Histopathology. 2013 May;62(6):908-15.
Title: Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer.
Author: Staton, Carolyn A|Koay, Ivan|Wu, Jessie M|Hoh, Leslie|Reed, Malcolm W R|Brown, Nicola J
PMID: 23551578
Journal: Invest New Drugs. 2014 Aug;32(4):653-60.
Title: A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors.
Author: Weekes, Colin D|Beeram, Muralidhar|Tolcher, Anthony W|Papadopoulos, Kyriakos P|Gore, Lia|Hegde, Priti|Xin, Yan|Yu, Ron|Shih, L Mason|Xiang, Hong|Brachmann, Rainer K|Patnaik, Amita
PMID: 24604265
Journal: Expert Opin Ther Targets. 2015 Feb;19(2):147-61.
Title: Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases.
Author: Chaudhary, Belal|Elkord, Eyad
PMID: 25351619
Journal: Front Oncol. 2015 Jun 3;5:125.
Title: Neuropilin-1 as Therapeutic Target for Malignant Melanoma.
Author: Graziani, Grazia|Lacal, Pedro M
PMID: 26090340
Journal: Cancer Gene Ther. 2016 May;23(5):125-32.
Title: VEGF121 and VEGF165 differentially promote vessel maturation and tumor growth in mice and humans.
Author: Kazemi, M|Carrer, A|Moimas, S|Zandona, L|Bussani, R|Casagranda, B|Palmisano, S|Prelazzi, P|Giacca, M|Zentilin, L|De Manzini, N|Giacca, M|Zacchigna, S
PMID: 27033458
Journal: Oncotarget. 2016 May 31;7(22):32449-61.
Title: Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting.
Author: Kim, Ji-Young|Han, Ji-Hae|Park, Geon|Seo, Young-Woo|Yun, Cheol-Won|Lee, Byung-Chul|Bae, Jeehyeon|Moon, Ae Ran|Kim, Tae-Hyoung
PMID: 27083053
Journal: Clin Cancer Res. 2016 Oct 15;22(20):5058-5067.
Title: BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer.
Author: Benson, Al B 3rd|Kiss, Igor|Bridgewater, John|Eskens, Ferry A L M|Sasse, Carolyn|Vossen, Sandra|Chen, Jihong|Van Sant, Chip|Ball, Howard A|Keating, Anne|Krivoshik, Andrew
PMID: 27401244
Journal: Oncotarget. 2016 Sep 27;7(39):63124-63137.
Title: DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling.
Author: Huang, Shiu-Wen|Lien, Jin-Cherng|Kuo, Sheng-Chu|Huang, Tur-Fu
PMID: 27517319
Journal: Cell Adh Migr. 2016 Nov;10(6):692-699.
Title: The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems.
Author: Ito, Daisuke|Kumanogoh, Atsushi
PMID: 27736304
Journal: Mol Carcinog. 2017 Jan;56(1):18-35.
Title: Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.
Author: Zakraoui, Ons|Marcinkiewicz, Cezary|Aloui, Zohra|Othman, Houcemeddine|Grepin, Renaud|Haoues, Meriam|Essafi, Makram|Srairi-Abid, Najet|Gasmi, Ammar|Karoui, Habib|Pages, Gilles|Essafi-Benkhadir, Khadija
PMID: 26824338
Journal: Drug Des Devel Ther. 2017 Jan 11;11:177-184.
Title: Immunotherapy for the treatment of colorectal tumors: focus on approved and in-clinical-trial monoclonal antibodies.
Author: Francoso, Alex|Simioni, Patricia Ucelli
PMID: 28138221
Journal: Int J Oncol. 2018 Apr;52(4):1350-1362.
Title: VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells.
Author: Tomida, Chisato|Yamagishi, Naoko|Nagano, Hikaru|Uchida, Takayuki|Ohno, Ayako|Hirasaka, Katsuya|Nikawa, Takeshi|Teshima-Kondo, Shigetada
PMID: 29532881
Journal: Nucl Med Biol. 2018 Jul - Aug;62-63:54-62.
Title: (99m)Tc labeled D(LPR): A novel retro-inverso peptide for VEGF receptor-1 targeted tumor imaging.
Author: Rezazadeh, Farzaneh|Sadeghzadeh, Nourollah|Abedi, Seyed Mohammad|Abediankenari, Saeid
PMID: 29885559
Journal: Clin Chim Acta. 2018 Oct;485:158-165.
Title: Neuropilin 1 (NRP1) is a novel tumor marker in hepatocellular carcinoma.
Author: Lin, Jiafei|Zhang, Yingwei|Wu, Jiemin|Li, Li|Chen, Ning|Ni, Peihua|Song, Lihua|Liu, Xiangfan
PMID: 29966621
Journal: Stroke. 2018 Nov;49(11):2733-2742.
Title: Cancer Exacerbates Ischemic Brain Injury Via Nrp1 (Neuropilin 1)-Mediated Accumulation of Regulatory T Cells Within the Tumor.
Author: Wang, Long|Zhou, Yuxi|Yin, Jiemin|Gan, Yu|Wang, Xin|Wen, Daxiang|Thomson, Angus W|Hu, Xiaoming|Yang, Liqun|Stetler, R Anne|Li, Peiying|Yu, Weifeng
PMID: 30355201