Primary Site >> Colorectal Cancer
Gene >> NRP1
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis. PMID: 15161648 |
Ref: The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer. PMID: 16391856 Ref: [Mechanisms of metastasis and molecular markers of malignant tumor progression. I. Colorectal cancer]. PMID: 17013365 |
Ref: Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients. PMID: 18086000 |
Ref: No functional and transductional significance of specific neuropilin 1 siRNA inhibition in colon carcinoma cell lines lacking VEGF receptor 2. PMID: 19360289 Ref: Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. PMID: 19826039 |
Ref: Semaphorin 3E, an exception to the rule. PMID: 20664165 Ref: Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation. PMID: 20950431 Ref: Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study). PMID: 21036743 |
Ref: Short-chain fatty acid level and field cancerization show opposing associations with enteroendocrine cell number and neuropilin expression in patients with colorectal adenoma. PMID: 21401950 Ref: NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells. PMID: 21483694 |
Ref: microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer. PMID: 22134529 Ref: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo. PMID: 23259795 |
Ref: Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer. PMID: 23551578 Ref: Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy. PMID: 24149180 |
Ref: A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors. PMID: 24604265 |
Ref: Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases. PMID: 25351619 Ref: Neuropilin-1 as Therapeutic Target for Malignant Melanoma. PMID: 26090340 |
Ref: VEGF121 and VEGF165 differentially promote vessel maturation and tumor growth in mice and humans. PMID: 27033458 Ref: Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting. PMID: 27083053 Ref: BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer. PMID: 27401244 Ref: DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling. PMID: 27517319 Ref: The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems. PMID: 27736304 |
Ref: Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression. PMID: 26824338 Ref: Immunotherapy for the treatment of colorectal tumors: focus on approved and in-clinical-trial monoclonal antibodies. PMID: 28138221 |
Ref: VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells. PMID: 29532881 Ref: (99m)Tc labeled D(LPR): A novel retro-inverso peptide for VEGF receptor-1 targeted tumor imaging. PMID: 29885559 Ref: Neuropilin 1 (NRP1) is a novel tumor marker in hepatocellular carcinoma. PMID: 29966621 Ref: Cancer Exacerbates Ischemic Brain Injury Via Nrp1 (Neuropilin 1)-Mediated Accumulation of Regulatory T Cells Within the Tumor. PMID: 30355201 |