Primary Site >> Liver Cancer
Gene >> NRAS
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17059-64. | ||||||||||
| Title: | Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse. | ||||||||||
| Author: | Carlson, Corey M|Frandsen, Joel L|Kirchhof, Nicole|McIvor, R Scott|Largaespada, David A | ||||||||||
| PMID: | 16286660 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 2011 Mar;53(3):781-90. | ||||||||||
| Title: | Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system. | ||||||||||
| Author: | Keng, Vincent W|Tschida, Barbara R|Bell, Jason B|Largaespada, David A | ||||||||||
| PMID: | 21374658 | ||||||||||
| 3. | |||||||||||
| Journal: | Nature. 2011 Nov 9;479(7374):547-51. | ||||||||||
| Title: | Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. | ||||||||||
| Author: | Kang, Tae-Won|Yevsa, Tetyana|Woller, Norman|Hoenicke, Lisa|Wuestefeld, Torsten|Dauch, Daniel|Hohmeyer, Anja|Gereke, Marcus|Rudalska, Ramona|Potapova, Anna|Iken, Marcus|Vucur, Mihael|Weiss, Siegfried|Heikenwalder, Mathias|Khan, Sadaf|Gil, Jesus|Bruder, Dun | ||||||||||
| PMID: | 22080947 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncologist. 2014 Mar;19(3):235-42. | ||||||||||
| Title: | New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. | ||||||||||
| Author: | Ross, Jeffrey S|Wang, Kai|Gay, Laurie|Al-Rohil, Rami|Rand, Janne V|Jones, David M|Lee, Hwa J|Sheehan, Christine E|Otto, Geoff A|Palmer, Gary|Yelensky, Roman|Lipson, Doron|Morosini, Deborah|Hawryluk, Matthew|Catenacci, Daniel V T|Miller, Vincent A|Churi, C | ||||||||||
| PMID: | 24563076 | ||||||||||
| 5. | |||||||||||
| Journal: | Clin Cancer Res. 2014 May 1;20(9):2410-23. | ||||||||||
| Title: | BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma. | ||||||||||
| Author: | Breunig, Christian|Mueller, Bernadett J|Umansky, Ludmila|Wahl, Kristin|Hoffmann, Katrin|Lehner, Frank|Manns, Michael P|Bantel, Heike|Falk, Christine S | ||||||||||
| PMID: | 24573550 | ||||||||||
| 6. | |||||||||||
| Journal: | PLoS One. 2014 May 5;9(5):e95307. | ||||||||||
| Title: | Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation. | ||||||||||
| Author: | Ding, Xiao|Yang, Yuan|Han, Baoda|Du, Chengzhi|Xu, Naiqing|Huang, Huanwei|Cai, Tao|Zhang, Aiqun|Han, Ze-Guang|Zhou, Weiping|Chen, Liang | ||||||||||
| PMID: | 24798046 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncotarget. 2014 May 30;5(10):3012-22. | ||||||||||
| Title: | Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing. | ||||||||||
| Author: | Janku, Filip|Kaseb, Ahmed O|Tsimberidou, Apostolia M|Wolff, Robert A|Kurzrock, Razelle | ||||||||||
| PMID: | 24931142 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncol Lett. 2014 Sep;8(3):1249-1254. | ||||||||||
| Title: | Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma. | ||||||||||
| Author: | Hou, Wenmin|Liu, Jibin|Chen, Peizhan|Wang, Hui|Ye, Bang-Ce|Qiang, Fulin | ||||||||||
| PMID: | 25120700 | ||||||||||
| 9. | |||||||||||
| Journal: | Hepatology. 2015 Mar;61(3):942-52. | ||||||||||
| Title: | Differential effects of targeting Notch receptors in a mouse model of liver cancer. | ||||||||||
| Author: | Huntzicker, Erik G|Hotzel, Kathy|Choy, Lisa|Che, Li|Ross, Jed|Pau, Gregoire|Sharma, Neeraj|Siebel, Christian W|Chen, Xin|French, Dorothy M | ||||||||||
| PMID: | 25311838 | ||||||||||
| 10. | |||||||||||
| Journal: | Elife. 2015 Jan 26;4. | ||||||||||
| Title: | Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. | ||||||||||
| Author: | Raouf, Samrrah|Weston, Claire|Yucel, Nora | ||||||||||
| PMID: | 25621566 | ||||||||||
| 11. | |||||||||||
| Journal: | Chem Biol Interact. 2015 Dec 5;242:107-22. | ||||||||||
| Title: | Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Bhullar, Khushwant S|Jha, Amitabh|Rupasinghe, H P Vasantha | ||||||||||
| PMID: | 26409325 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Aug 1;8(8):8821-31. eCollection 2015. | ||||||||||
| Title: | Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression. | ||||||||||
| Author: | Zoheir, Khairy M A|Abd-Rabou, Ahmed A|Harisa, Gamaleldin I|Ashour, Abdelkader E|Ahmad, Sheikh Fayaz|Attia, Sabry M|Bakheet, Saleh A|Abdel-Hamied, Hala E|Abd-Allah, Adel R|Kumar, Ashok | ||||||||||
| PMID: | 26464624 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncogene. 2016 May 19;35(20):2547-61. | ||||||||||
| Title: | Stamping out RAF and MEK1/2 to inhibit the ERK1/2 pathway: an emerging threat to anticancer therapy. | ||||||||||
| Author: | Mandal, R|Becker, S|Strebhardt, K | ||||||||||
| PMID: | 26364606 | ||||||||||
| 14. | |||||||||||
| Journal: | Tumour Biol. 2016 Oct;37(10):13927-13939. | ||||||||||
| Title: | IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells. | ||||||||||
| Author: | Zoheir, Khairy Ma|Abd-Rabou, Ahmed A|Harisa, Gamaleldin I|Kumar, Ashok|Ahmad, Sheikh Fayaz|Ansari, Mushtaq Ahmad|Abd-Allah, Adel R | ||||||||||
| PMID: | 27488117 | ||||||||||
| 15. | |||||||||||
| Journal: | Nat Med. 2016 Jul;22(7):744-53. | ||||||||||
| Title: | A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. | ||||||||||
| Author: | Dauch, Daniel|Rudalska, Ramona|Cossa, Giacomo|Nault, Jean-Charles|Kang, Tae-Won|Wuestefeld, Torsten|Hohmeyer, Anja|Imbeaud, Sandrine|Yevsa, Tetyana|Hoenicke, Lisa|Pantsar, Tatu|Bozko, Przemyslaw|Malek, Nisar P|Longerich, Thomas|Laufer, Stefan|Poso, Antti| | ||||||||||
| PMID: | 27213815 | ||||||||||
| 16. | |||||||||||
| Journal: | Hepatology. 2016 Jun;63(6):1888-99. | ||||||||||
| Title: | Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. | ||||||||||
| Author: | Matter, Matthias S|Marquardt, Jens U|Andersen, Jesper B|Quintavalle, Cristina|Korokhov, Nikolay|Stauffer, Jim K|Kaji, Kosuke|Decaens, Thomas|Quagliata, Luca|Elloumi, Fathi|Hoang, Tanya|Molinolo, Alfredo|Conner, Elizabeth A|Weber, Achim|Heikenwalder, Mathi | ||||||||||
| PMID: | 26844528 | ||||||||||
| 17. | |||||||||||
| Journal: | J Hepatol. 2016 Apr;64(4):881-90. | ||||||||||
| Title: | Monocytes promote liver carcinogenesis in an oncogene-specific manner. | ||||||||||
| Author: | Juric, Vladislava|Ruffell, Brian|Evason, Kimberley J|Hu, Junjie|Che, Li|Wang, Linlin|Chen, Xin|Bishop, J Michael | ||||||||||
| PMID: | 26639397 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2017 May 9;12(5):e0176562. | ||||||||||
| Title: | Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation. | ||||||||||
| Author: | Sorenson, Eric C|Khanin, Raya|Bamboat, Zubin M|Cavnar, Michael J|Kim, Teresa S|Sadot, Eran|Zeng, Shan|Greer, Jonathan B|Seifert, Adrian M|Cohen, Noah A|Crawley, Megan H|Green, Benjamin L|Klimstra, David S|DeMatteo, Ronald P | ||||||||||
| PMID: | 28486549 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Biol Ther. 2017 Jul 3;18(7):505-512. | ||||||||||
| Title: | CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. | ||||||||||
| Author: | Gao, Mingming|Liu, Dexi | ||||||||||
| PMID: | 28513320 | ||||||||||
| 20. | |||||||||||
| Journal: | Sci Rep. 2017 Oct 17;7(1):13419. | ||||||||||
| Title: | The construction of intrahepatic cholangiocarcinoma model in zebrafish. | ||||||||||
| Author: | Wang, Jing|Leng, Xiaoqian|Wang, Guiping|Wan, Xiaoyang|Cao, Hong | ||||||||||
| PMID: | 29042681 | ||||||||||
| 21. | |||||||||||
| Journal: | Ann Surg Treat Res. 2017 Oct;93(4):173-180. | ||||||||||
| Title: | Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy. | ||||||||||
| Author: | Jung, Joohee|Kim, Jisup|Lim, Hyun Kyung|Kim, Kyoung Mee|Lee, Yun Sun|Park, Joon Seong|Yoon, Dong Sup | ||||||||||
| PMID: | 29094026 | ||||||||||
| 22. | |||||||||||
| Journal: | Pathol Res Pract. 2017 Dec;213(12):1494-1509. | ||||||||||
| Title: | Down-regulation of miR-26a-5p in hepatocellular carcinoma: A qRT-PCR and bioinformatics study. | ||||||||||
| Author: | Liang, Liang|Zeng, Jiang-Hui|Wang, Jie-Yu|He, Rong-Quan|Ma, Jie|Chen, Gang|Cai, Xiao-Yong|Hu, Xiao-Hua | ||||||||||
| PMID: | 29113686 | ||||||||||
| 23. | |||||||||||
| Journal: | J Cancer. 2018 Jan 1;9(1):1-12. | ||||||||||
| Title: | Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. | ||||||||||
| Author: | Tsirulnikov, Kirill|Duarte, Sergio|Ray, Anamika|Datta, Nakul|Zarrinpar, Ali|Hwang, Lin|Faull, Kym|Pushkin, Alexander|Kurtz, Ira | ||||||||||
| PMID: | 29290764 | ||||||||||
| 24. | |||||||||||
| Journal: | J Med Virol. 2018 Sep;90(9):1516-1523. | ||||||||||
| Title: | Study of promoter hypomethylation profiles of RAS oncogenes in hepatocellular carcinoma derived from hepatitis C virus genotype 3a in Pakistani population. | ||||||||||
| Author: | Maryam, Maria|Idrees, Muhammad | ||||||||||
| PMID: | 29742286 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2018 Sep 28;9(76):34279-34288. | ||||||||||
| Title: | Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach. | ||||||||||
| Author: | Del Carmen, Sofia|Sayagues, Jose Maria|Bengoechea, Oscar|Anduaga, Maria Fernanda|Alcazar, Jose Antonio|Gervas, Ruth|Garcia, Jacinto|Orfao, Alberto|Bellvis, Luis Munoz|Sarasquete, Maria Eugenia|Del Mar Abad, Maria | ||||||||||
| PMID: | 30344942 | ||||||||||