Primary Site >> Liver Cancer
Gene >> NRAS
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Ref: Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse. PMID: 16286660 |
Ref: Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system. PMID: 21374658 Ref: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. PMID: 22080947 |
Ref: New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. PMID: 24563076 Ref: BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma. PMID: 24573550 Ref: Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation. PMID: 24798046 Ref: Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing. PMID: 24931142 Ref: Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma. PMID: 25120700 |
Ref: Differential effects of targeting Notch receptors in a mouse model of liver cancer. PMID: 25311838 Ref: Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. PMID: 25621566 Ref: Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. PMID: 26409325 Ref: Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression. PMID: 26464624 |
Ref: Stamping out RAF and MEK1/2 to inhibit the ERK1/2 pathway: an emerging threat to anticancer therapy. PMID: 26364606 Ref: Monocytes promote liver carcinogenesis in an oncogene-specific manner. PMID: 26639397 Ref: Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. PMID: 26844528 Ref: A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. PMID: 27213815 Ref: IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells. PMID: 27488117 |
Ref: Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation. PMID: 28486549 Ref: CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. PMID: 28513320 Ref: The construction of intrahepatic cholangiocarcinoma model in zebrafish. PMID: 29042681 Ref: Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy. PMID: 29094026 Ref: Down-regulation of miR-26a-5p in hepatocellular carcinoma: A qRT-PCR and bioinformatics study. PMID: 29113686 |
Ref: Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. PMID: 29290764 Ref: Study of promoter hypomethylation profiles of RAS oncogenes in hepatocellular carcinoma derived from hepatitis C virus genotype 3a in Pakistani population. PMID: 29742286 Ref: Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach. PMID: 30344942 |