Primary Site >> Biliary tract Cancer
Gene >> NRAS
| 1. | |||||||||||
| Journal: | Int J Cancer. 1994 Oct 1;59(1):39-42. | ||||||||||
| Title: | ras-family gene mutations in neoplasia of the ampulla of Vater. | ||||||||||
| Author: | Scarpa, A|Zamboni, G|Achille, A|Capelli, P|Bogina, G|Iacono, C|Serio, G|Accolla, R S | ||||||||||
| PMID: | 7927901 | ||||||||||
| 2. | |||||||||||
| Journal: | Hum Pathol. 1999 Jan;30(1):21-5. | ||||||||||
| Title: | Gallbladder adenomas have molecular abnormalities different from those present in gallbladder carcinomas. | ||||||||||
| Author: | Wistuba, I I|Miquel, J F|Gazdar, A F|Albores-Saavedra, J | ||||||||||
| PMID: | 9923922 | ||||||||||
| 3. | |||||||||||
| Journal: | J Gastrointest Surg. 2009 Aug;13(8):1510-6. | ||||||||||
| Title: | Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas. | ||||||||||
| Author: | Schonleben, Frank|Qiu, Wanglong|Allendorf, John D|Chabot, John A|Remotti, Helen E|Su, Gloria H | ||||||||||
| PMID: | 19440799 | ||||||||||
| 4. | |||||||||||
| Journal: | BMC Cancer. 2011 Feb 8;11:60. | ||||||||||
| Title: | Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma. | ||||||||||
| Author: | Deshpande, Vikram|Nduaguba, Afamefuna|Zimmerman, Stephanie M|Kehoe, Sarah M|Macconaill, Laura E|Lauwers, Gregory Y|Ferrone, Cristina|Bardeesy, Nabeel|Zhu, Andrew X|Hezel, Aram F | ||||||||||
| PMID: | 21303542 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncologist. 2012;17(1):72-9. | ||||||||||
| Title: | Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. | ||||||||||
| Author: | Borger, Darrell R|Tanabe, Kenneth K|Fan, Kenneth C|Lopez, Hector U|Fantin, Valeria R|Straley, Kimberly S|Schenkein, David P|Hezel, Aram F|Ancukiewicz, Marek|Liebman, Hannah M|Kwak, Eunice L|Clark, Jeffrey W|Ryan, David P|Deshpande, Vikram|Dias-Santagata, | ||||||||||
| PMID: | 22180306 | ||||||||||
| 6. | |||||||||||
| Journal: | Hum Pathol. 2013 Jul;44(7):1216-22. | ||||||||||
| Title: | Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. | ||||||||||
| Author: | Voss, Jesse S|Holtegaard, Leonard M|Kerr, Sarah E|Fritcher, Emily G Barr|Roberts, Lewis R|Gores, Gregory J|Zhang, Jun|Highsmith, W Edward|Halling, Kevin C|Kipp, Benjamin R | ||||||||||
| PMID: | 23391413 | ||||||||||
| 7. | |||||||||||
| Journal: | Mod Pathol. 2014 May;27(5):731-9. | ||||||||||
| Title: | High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases. | ||||||||||
| Author: | Jang, Sejin|Chun, Sung-Min|Hong, Seoung-Mo|Sung, Chang Ohk|Park, Hosub|Kang, Hyo Jeong|Kim, Kyu-pyo|Lee, Young Joo|Yu, Eunsil | ||||||||||
| PMID: | 24186137 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncologist. 2014 Mar;19(3):235-42. | ||||||||||
| Title: | New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. | ||||||||||
| Author: | Ross, Jeffrey S|Wang, Kai|Gay, Laurie|Al-Rohil, Rami|Rand, Janne V|Jones, David M|Lee, Hwa J|Sheehan, Christine E|Otto, Geoff A|Palmer, Gary|Yelensky, Roman|Lipson, Doron|Morosini, Deborah|Hawryluk, Matthew|Catenacci, Daniel V T|Miller, Vincent A|Churi, C | ||||||||||
| PMID: | 24563076 | ||||||||||
| 9. | |||||||||||
| Journal: | Ann Surg Oncol. 2014 Nov;21(12):3827-34. | ||||||||||
| Title: | Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets. | ||||||||||
| Author: | Zhu, Andrew X|Borger, Darrell R|Kim, Yuhree|Cosgrove, David|Ejaz, Aslam|Alexandrescu, Sorin|Groeschl, Ryan Thomas|Deshpande, Vikram|Lindberg, James M|Ferrone, Cristina|Sempoux, Christine|Yau, Thomas|Poon, Ronnie|Popescu, Irinel|Bauer, Todd W|Gamblin, T Cl | ||||||||||
| PMID: | 24889489 | ||||||||||
| 10. | |||||||||||
| Journal: | Virchows Arch. 2015 Apr;466(4):393-402. | ||||||||||
| Title: | Microsatellite instability in gallbladder carcinoma. | ||||||||||
| Author: | Moy, Andrea P|Shahid, Mohammad|Ferrone, Cristina R|Borger, Darrell R|Zhu, Andrew X|Ting, David|Deshpande, Vikram | ||||||||||
| PMID: | 25680569 | ||||||||||
| 11. | |||||||||||
| Journal: | Exp Mol Pathol. 2015 Oct;99(2):240-4. | ||||||||||
| Title: | Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing. | ||||||||||
| Author: | Putra, Juan|de Abreu, Francine B|Peterson, Jason D|Pipas, J Marc|Mody, Kabir|Amos, Christopher I|Tsongalis, Gregory J|Suriawinata, Arief A | ||||||||||
| PMID: | 26189129 | ||||||||||
| 12. | |||||||||||
| Journal: | Mod Pathol. 2015 Aug;28(8):1123-9. | ||||||||||
| Title: | Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2). | ||||||||||
| Author: | Hechtman, Jaclyn F|Liu, Weiguo|Sadowska, Justyna|Zhen, Lisa|Borsu, Laetitia|Arcila, Maria E|Won, Helen H|Shah, Ronak H|Berger, Michael F|Vakiani, Efsevia|Shia, Jinru|Klimstra, David S | ||||||||||
| PMID: | 25975284 | ||||||||||
| 13. | |||||||||||
| Journal: | J Clin Pathol. 2016 May;69(5):403-8. | ||||||||||
| Title: | Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets. | ||||||||||
| Author: | Lee, Hwajeong|Wang, Kai|Johnson, Adrienne|Jones, David M|Ali, Siraj M|Elvin, Julia A|Yelensky, Roman|Lipson, Doron|Miller, Vincent A|Stephens, Philip J|Javle, Milind|Ross, Jeffrey S | ||||||||||
| PMID: | 26500333 | ||||||||||
| 14. | |||||||||||
| Journal: | Ann Surg Oncol. 2016 May;23(5):1699-707. | ||||||||||
| Title: | Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients. | ||||||||||
| Author: | Ruzzenente, Andrea|Fassan, Matteo|Conci, Simone|Simbolo, Michele|Lawlor, Rita T|Pedrazzani, Corrado|Capelli, Paola|D'Onofrio, Mirko|Iacono, Calogero|Scarpa, Aldo|Guglielmi, Alfredo | ||||||||||
| PMID: | 26717940 | ||||||||||
| 15. | |||||||||||
| Journal: | Transl Oncol. 2016 Jun;9(3):173-8. | ||||||||||
| Title: | Genomic Alterations in Biliary Tract Cancer Using Targeted Sequencing. | ||||||||||
| Author: | Yoo, Kwai Han|Kim, Nayoung K D|Kwon, Woo Il|Lee, Chung|Kim, Sun Young|Jang, Jiryeon|Ahn, Jungmi|Kang, Mihyun|Jang, Hyojin|Kim, Seung Tae|Ahn, Soomin|Jang, Kee-Taek|Park, Young Suk|Park, Woong-Yang|Lee, Jeeyun|Heo, Jin Seok|Park, Joon Oh | ||||||||||
| PMID: | 27267833 | ||||||||||
| 16. | |||||||||||
| Journal: | Pathol Res Pract. 2017 Aug;213(8):1010-1013. | ||||||||||
| Title: | Adenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components. | ||||||||||
| Author: | Galuppini, Francesca|Salmaso, Roberta|Valentini, Elisa|Lanza, Cristiano|Maretto, Isacco|Nitti, Donato|Rugge, Massimo|Fassan, Matteo | ||||||||||
| PMID: | 28698100 | ||||||||||
| 17. | |||||||||||
| Journal: | Ecancermedicalscience. 2017 Aug 7;11:757. | ||||||||||
| Title: | Mutational frequency of KRAS, NRAS, IDH2, PIK3CA, and EGFR in North Indian gallbladder cancer patients. | ||||||||||
| Author: | Sharma, Aarti|Kumar, Ashok|Kumari, Niraj|Krishnani, Narendra|Rastogi, Neeraj | ||||||||||
| PMID: | 28900470 | ||||||||||
| 18. | |||||||||||
| Journal: | Sci Rep. 2017 Oct 17;7(1):13419. | ||||||||||
| Title: | The construction of intrahepatic cholangiocarcinoma model in zebrafish. | ||||||||||
| Author: | Wang, Jing|Leng, Xiaoqian|Wang, Guiping|Wan, Xiaoyang|Cao, Hong | ||||||||||
| PMID: | 29042681 | ||||||||||
| 19. | |||||||||||
| Journal: | Invest New Drugs. 2018 May 22. pii: 10.1007/s10637-018-0600-2. | ||||||||||
| Title: | Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer. | ||||||||||
| Author: | Finn, R S|Ahn, D H|Javle, M M|Tan, B R Jr|Weekes, C D|Bendell, J C|Patnaik, A|Khan, G N|Laheru, D|Chavira, R|Christy-Bittel, J|Barrett, E|Sawyer, M B|Bekaii-Saab, Tanios S | ||||||||||
| PMID: | 29785570 | ||||||||||