Primary Site >> Colorectal Cancer
Gene >> NR4A1
| 1. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 1984;108(3):345-50. | ||||||||||
| Title: | Effects of steroid hormone therapy on primarily xenotransplanted human colorectal adenocarcinomas. | ||||||||||
| Author: | Izbicki, J R|Schmitz, R|Hoppen, H O|Izbicki, W|Troidl, H | ||||||||||
| PMID: | 6511808 | ||||||||||
| 2. | |||||||||||
| Journal: | Br J Cancer. 1988 Aug;58(2):189-90. | ||||||||||
| Title: | The efficacy of 5-fluorouracil in human colorectal cancer is not enhanced by thymidylate synthetase inhibition with CB3717 (N10-propargyl-5,8 dideazafolic acid). | ||||||||||
| Author: | Cantwell, B M|Harris, A L | ||||||||||
| PMID: | 3166908 | ||||||||||
| 3. | |||||||||||
| Journal: | Br J Cancer. 1988 Jun;57(6):628-9. | ||||||||||
| Title: | Phase II study of the thymidylate synthetase inhibitor CB3717 (N10-propargyl-5,8-dideazafolic acid) in colorectal cancer. | ||||||||||
| Author: | Harding, M J|Cantwell, B M|Milstead, R A|Harris, A L|Kaye, S B | ||||||||||
| PMID: | 3408648 | ||||||||||
| 4. | |||||||||||
| Journal: | Ann Oncol. 1995 Nov;6(9):871-81. | ||||||||||
| Title: | Folate-based thymidylate synthase inhibitors as anticancer drugs. | ||||||||||
| Author: | Jackman, A L|Calvert, A H | ||||||||||
| PMID: | 8624289 | ||||||||||
| 5. | |||||||||||
| Journal: | Biol Pharm Bull. 2000 Jul;23(7):815-9. | ||||||||||
| Title: | Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells. | ||||||||||
| Author: | Kang, H J|Song, M J|Choung, S Y|Kim, S J|Le, M O | ||||||||||
| PMID: | 10919358 | ||||||||||
| 6. | |||||||||||
| Journal: | Curr Opin Investig Drugs. 2000 Sep;1(1):135-40. | ||||||||||
| Title: | Tezacitabine Hoechst Marion Roussel. | ||||||||||
| Author: | Seley, K L | ||||||||||
| PMID: | 11249589 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Treat Rev. 2002 Feb;28(1):27-47. | ||||||||||
| Title: | Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer. | ||||||||||
| Author: | Aschele, C|Lonardi, S|Monfardini, S | ||||||||||
| PMID: | 12027413 | ||||||||||
| 8. | |||||||||||
| Journal: | Thromb Haemost. 2003 Jun;89(6):1098-106. | ||||||||||
| Title: | Impact of pretreatment thrombocytosis on survival in primary breast cancer. | ||||||||||
| Author: | Taucher, Susanne|Salat, Andreas|Gnant, Michael|Kwasny, Werner|Mlineritsch, Brigitte|Menzel, Rainer-Christian|Schmid, Marianne|Smola, Michael G|Stierer, Michael|Tausch, Christoph|Galid, Arik|Steger, Gunther|Jakesz, Raimund | ||||||||||
| PMID: | 12783124 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2003 Sep 1;63(17):5401-7. | ||||||||||
| Title: | TR3/Nur77 in colon cancer cell apoptosis. | ||||||||||
| Author: | Wilson, Andrew J|Arango, Diego|Mariadason, John M|Heerdt, Barbara G|Augenlicht, Leonard H | ||||||||||
| PMID: | 14500374 | ||||||||||
| 10. | |||||||||||
| Journal: | J Clin Oncol. 2003 Oct 1;21(19):3594-600. | ||||||||||
| Title: | High p27Kip1 expression predicts superior relapse-free and overall survival for premenopausal women with early-stage breast cancer receiving adjuvant treatment with tamoxifen plus goserelin. | ||||||||||
| Author: | Pohl, Gudrun|Rudas, Margaretha|Dietze, Otto|Lax, Sigurd|Markis, Eva|Pirker, Robert|Zielinski, Christoph C|Hausmaninger, Hubert|Kubista, Ernst|Samonigg, Hellmut|Jakesz, Raimund|Filipits, Martin | ||||||||||
| PMID: | 14512390 | ||||||||||
| 11. | |||||||||||
| Journal: | J Clin Oncol. 2005 Feb 20;23(6):1161-8. | ||||||||||
| Title: | Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group. | ||||||||||
| Author: | Filipits, Martin|Pohl, Gudrun|Rudas, Margaretha|Dietze, Otto|Lax, Sigurd|Grill, Renate|Pirker, Robert|Zielinski, Christoph C|Hausmaninger, Hubert|Kubista, Ernst|Samonigg, Hellmut|Jakesz, Raimund | ||||||||||
| PMID: | 15718312 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2007 Jan 15;67(2):674-83. | ||||||||||
| Title: | Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways. | ||||||||||
| Author: | Cho, Sung Dae|Yoon, Kyungsil|Chintharlapalli, Sudhakar|Abdelrahim, Maen|Lei, Ping|Hamilton, Stanley|Khan, Shaheen|Ramaiah, Shashi K|Safe, Stephen | ||||||||||
| PMID: | 17234778 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Carcinog. 2008 Apr;47(4):252-63. | ||||||||||
| Title: | 1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells. | ||||||||||
| Author: | Cho, Sung Dae|Lei, Ping|Abdelrahim, Maen|Yoon, Kyungsil|Liu, Shengxi|Guo, Jingjing|Papineni, Sabitha|Chintharlapalli, Sudhakar|Safe, Stephen | ||||||||||
| PMID: | 17957723 | ||||||||||
| 14. | |||||||||||
| Journal: | Breast Cancer Res Treat. 2008 Nov;112(1):203-13. Epub 2007 Dec 22. | ||||||||||
| Title: | Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: a phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17). | ||||||||||
| Author: | Mlineritsch, Brigitte|Tausch, Christoph|Singer, Christian|Luschin-Ebengreuth, Gero|Jakesz, Raimund|Ploner, Ferdinand|Stierer, Michael|Melbinger, Elisabeth|Menzel, Christian|Urbania, Andrea|Fridrik, Michael|Steger, Gunther|Wohlmuth, Peter|Gnant, Michael|Gr | ||||||||||
| PMID: | 18158620 | ||||||||||
| 15. | |||||||||||
| Journal: | Carcinogenesis. 2008 Jun;29(6):1139-47. | ||||||||||
| Title: | 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase. | ||||||||||
| Author: | Lei, Ping|Abdelrahim, Maen|Cho, Sung Dae|Liu, Shengxi|Chintharlapalli, Sudhakar|Safe, Stephen | ||||||||||
| PMID: | 18460448 | ||||||||||
| 16. | |||||||||||
| Journal: | Clin Cancer Res. 2008 May 15;14(10):3011-21. | ||||||||||
| Title: | Bcl-B expression in human epithelial and nonepithelial malignancies. | ||||||||||
| Author: | Krajewska, Maryla|Kitada, Shinichi|Winter, Jane N|Variakojis, Daina|Lichtenstein, Alan|Zhai, Dayong|Cuddy, Michael|Huang, Xianshu|Luciano, Frederic|Baker, Cheryl H|Kim, Hoguen|Shin, Eunah|Kennedy, Susan|Olson, Allen H|Badzio, Andrzej|Jassem, Jacek|Meinhol | ||||||||||
| PMID: | 18483366 | ||||||||||
| 17. | |||||||||||
| Journal: | Expert Opin Pharmacother. 2008 Jun;9(9):1619-22. | ||||||||||
| Title: | Is long-term adjuvant treatment of breast cancer with anastrozole indicated? | ||||||||||
| Author: | Doggrell, Sheila A | ||||||||||
| PMID: | 18518790 | ||||||||||
| 18. | |||||||||||
| Journal: | J Clin Oncol. 2008 Jul 20;26(21):3631-7. | ||||||||||
| Title: | American Society of Clinical Oncology/National Comprehensive Cancer Network Quality Measures. | ||||||||||
| Author: | Desch, Christopher E|McNiff, Kristen K|Schneider, Eric C|Schrag, Deborah|McClure, Joan|Lepisto, Eva|Donaldson, Molla S|Kahn, Katherine L|Weeks, Jane C|Ko, Clifford Y|Stewart, Andrew K|Edge, Stephen B | ||||||||||
| PMID: | 18640941 | ||||||||||
| 19. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Sep 15;15(18):5888-94. | ||||||||||
| Title: | Low p27 expression predicts early relapse and death in postmenopausal hormone receptor-positive breast cancer patients receiving adjuvant tamoxifen therapy. | ||||||||||
| Author: | Filipits, Martin|Rudas, Margaretha|Heinzl, Harald|Jakesz, Raimund|Kubista, Ernst|Lax, Sigurd|Schippinger, Walter|Dietze, Otto|Greil, Richard|Stiglbauer, Wolfgang|Kwasny, Werner|Nader, Alexander|Stierer, Michael|Gnant, Michael F X | ||||||||||
| PMID: | 19723645 | ||||||||||
| 20. | |||||||||||
| Journal: | J Biol Chem. 2009 Nov 13;284(46):32178-87. | ||||||||||
| Title: | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. | ||||||||||
| Author: | Zhao, Ming|Wan, Zhu-li|Whittaker, Linda|Xu, Bin|Phillips, Nelson B|Katsoyannis, Panayotis G|Ismail-Beigi, Faramarz|Whittaker, Jonathan|Weiss, Michael A | ||||||||||
| PMID: | 19773552 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 May;66(1):141-50. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells. | ||||||||||
| Author: | Guo, Jingjing|Chintharlapalli, Sudhakar|Lee, Syng-ook|Cho, Sung Dae|Lei, Ping|Papineni, Sabitha|Safe, Stephen | ||||||||||
| PMID: | 19823826 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2010 Jan 15;70(2):609-20. | ||||||||||
| Title: | Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction. | ||||||||||
| Author: | Wilson, Andrew J|Chueh, Anderly C|Togel, Lars|Corner, Georgia A|Ahmed, Naseem|Goel, Sanjay|Byun, Do-Sun|Nasser, Shannon|Houston, Michele A|Jhawer, Minaxi|Smartt, Helena J M|Murray, Lucas B|Nicholas, Courtney|Heerdt, Barbara G|Arango, Diego|Augenlicht, Leo | ||||||||||
| PMID: | 20068171 | ||||||||||
| 23. | |||||||||||
| Journal: | FASEB J. 2011 Jan;25(1):192-205. | ||||||||||
| Title: | Regulation of Nur77 expression by beta-catenin and its mitogenic effect in colon cancer cells. | ||||||||||
| Author: | Wu, Hua|Lin, Yayu|Li, Wengang|Sun, Zhe|Gao, Weiwei|Zhang, Haiping|Xie, Lei|Jiang, Fuquan|Qin, Bin|Yan, Tingdong|Chen, Liqun|Zhao, Yi|Cao, Xihua|Wu, Yin|Lin, Bingzhen|Zhou, Hu|Wong, Alice Sze-Tsai|Zhang, Xiao-Kun|Zeng, Jin-Zhang | ||||||||||
| PMID: | 20847229 | ||||||||||
| 24. | |||||||||||
| Journal: | Biochem Soc Trans. 2011 Apr;39(2):688-93. | ||||||||||
| Title: | Inflammation: a role for NR4A orphan nuclear receptors? | ||||||||||
| Author: | McMorrow, Jason P|Murphy, Evelyn P | ||||||||||
| PMID: | 21428963 | ||||||||||
| 25. | |||||||||||
| Journal: | J Biol Chem. 2011 Aug 26;286(34):30003-9. | ||||||||||
| Title: | Nuclear orphan receptor NR4A2 modulates fatty acid oxidation pathways in colorectal cancer. | ||||||||||
| Author: | Holla, Vijaykumar R|Wu, Hong|Shi, Qiong|Menter, David G|DuBois, Raymond N | ||||||||||
| PMID: | 21757690 | ||||||||||
| 26. | |||||||||||
| Journal: | Gut. 2012 May;61(5):714-24. | ||||||||||
| Title: | The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling. | ||||||||||
| Author: | Chen, Hang-Zi|Liu, Qing-Feng|Li, Li|Wang, Wei-Jia|Yao, Lu-Ming|Yang, Meng|Liu, Bo|Chen, Wei|Zhan, Yan-Yan|Zhang, Ming-Qing|Cai, Jian-Chun|Zheng, Zhong-hui|Lin, Sheng-Cai|Li, Bo-An|Wu, Qiao | ||||||||||
| PMID: | 21873734 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2012 May 24;31(21):2653-67. | ||||||||||
| Title: | Inhibition of beta-catenin signaling by nongenomic action of orphan nuclear receptor Nur77. | ||||||||||
| Author: | Sun, Z|Cao, X|Jiang, M-M|Qiu, Y|Zhou, H|Chen, L|Qin, B|Wu, H|Jiang, F|Chen, J|Liu, J|Dai, Y|Chen, H-F|Hu, Q-Y|Wu, Z|Zeng, J-Z|Yao, X-S|Zhang, X-K | ||||||||||
| PMID: | 21986938 | ||||||||||
| 28. | |||||||||||
| Journal: | Carcinogenesis. 2012 Feb;33(2):301-11. | ||||||||||
| Title: | Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis. | ||||||||||
| Author: | Yao, Lu-ming|He, Jian-ping|Chen, Hang-zi|Wang, Yuan|Wang, Wei-jia|Wu, Rong|Yu, Chun-dong|Wu, Qiao | ||||||||||
| PMID: | 22159226 | ||||||||||
| 29. | |||||||||||
| Journal: | Mol Endocrinol. 2014 Oct;28(10):1729-39. | ||||||||||
| Title: | Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells. | ||||||||||
| Author: | Lee, Syng-Ook|Li, Xi|Hedrick, Erik|Jin, Un-Ho|Tjalkens, Ronald B|Backos, Donald S|Li, Li|Zhang, Yi|Wu, Qiao|Safe, Stephen | ||||||||||
| PMID: | 25099012 | ||||||||||
| 30. | |||||||||||
| Journal: | Carcinogenesis. 2014 Nov;35(11):2474-84. | ||||||||||
| Title: | Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin. | ||||||||||
| Author: | Wang, Jing-Ru|Gan, Wen-Juan|Li, Xiu-Ming|Zhao, Yuan-Yuan|Li, Ying|Lu, Xing-Xing|Li, Jian-Ming|Wu, Hua | ||||||||||
| PMID: | 25064356 | ||||||||||
| 31. | |||||||||||
| Journal: | Br J Cancer. 2014 Feb 18;110(4):935-45. | ||||||||||
| Title: | Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells. | ||||||||||
| Author: | To, S K Y|Zeng, W-J|Zeng, J-Z|Wong, A S T | ||||||||||
| PMID: | 24423919 | ||||||||||
| 32. | |||||||||||
| Journal: | Mol Cancer Res. 2015 Feb;13(2):281-92. | ||||||||||
| Title: | Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis. | ||||||||||
| Author: | Hu, Ying|Chau, Thinh|Liu, Hui-Xin|Liao, Degui|Keane, Ryan|Nie, Yuqiang|Yang, Hui|Wan, Yu-Jui Yvonne | ||||||||||
| PMID: | 25232032 | ||||||||||
| 33. | |||||||||||
| Journal: | Steroids. 2015 Mar;95:1-6. | ||||||||||
| Title: | Non-genomic effects of the NR4A1/Nur77/TR3/NGFIB orphan nuclear receptor. | ||||||||||
| Author: | Pawlak, Alicja|Strzadala, Leon|Kalas, Wojciech | ||||||||||
| PMID: | 25555471 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncology (Williston Park). 2015 Jul;29(7):473-8, 481. | ||||||||||
| Title: | The Role of Ovarian Suppression in Premenopausal Women With Hormone Receptor-Positive Early-Stage Breast Cancer. | ||||||||||
| Author: | Jain, Sarika|Santa-Maria, Cesar Augusto|Gradishar, William J | ||||||||||
| PMID: | 26178334 | ||||||||||
| 35. | |||||||||||
| Journal: | Endocr Relat Cancer. 2015 Oct;22(5):831-40. | ||||||||||
| Title: | Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy. | ||||||||||
| Author: | Hedrick, Erik|Lee, Syng-Ook|Doddapaneni, Ravi|Singh, Mandip|Safe, Stephen | ||||||||||
| PMID: | 26229035 | ||||||||||
| 36. | |||||||||||
| Journal: | Tumour Biol. 2016 Nov;37(11):14885-14894. | ||||||||||
| Title: | gamma-Aminobutyric acid inhibits the proliferation and increases oxaliplatin sensitivity in human colon cancer cells. | ||||||||||
| Author: | Song, Lihua|Du, Aiying|Xiong, Ying|Jiang, Jing|Zhang, Yao|Tian, Zhaofeng|Yan, Hongli | ||||||||||
| PMID: | 27644246 | ||||||||||
| 37. | |||||||||||
| Journal: | Mol Carcinog. 2017 Sep;56(9):2066-2075. | ||||||||||
| Title: | The nuclear orphan receptor NR4A1 regulates beta1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists. | ||||||||||
| Author: | Hedrick, Erik|Lee, Syng-Ook|Safe, Stephen | ||||||||||
| PMID: | 28418095 | ||||||||||
| 38. | |||||||||||
| Journal: | Nutr Rev. 2017 Jun 1;75(6):405-419. | ||||||||||
| Title: | Possible role of diet in cancer: systematic review and multiple meta-analyses of dietary patterns, lifestyle factors, and cancer risk. | ||||||||||
| Author: | Grosso, Giuseppe|Bella, Francesca|Godos, Justyna|Sciacca, Salvatore|Del Rio, Daniele|Ray, Sumantra|Galvano, Fabio|Giovannucci, Edward L | ||||||||||
| PMID: | 28969358 | ||||||||||
| 39. | |||||||||||
| Journal: | FASEB J. 2018 Sep 25:fj201801390R. | ||||||||||
| Title: | RARbeta acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells. | ||||||||||
| Author: | Hu, Ying|French, Samuel W|Chau, Thinh|Liu, Hui-Xin|Sheng, Lili|Wei, Fang|Stondell, Jesse|Garcia, Juan C|Du, Yanlei|Bowlus, Christopher L|Wan, Yu-Jui Yvonne | ||||||||||
| PMID: | 30252536 | ||||||||||
| 40. | |||||||||||
| Journal: | Gynecol Obstet Fertil Senol. 2018 Oct 29. pii: S2468-7189(18)30265-4. | ||||||||||
| Title: | [Contraception and cancer: CNGOF Contraception Guidelines]. | ||||||||||
| Author: | Pragout, D|Laurence, V|Baffet, H|Raccah-Tebeka, B|Rousset-Jablonski, C | ||||||||||
| PMID: | 30385358 | ||||||||||