Primary Site >> Liver Cancer
Gene >> NQO1
| 1. | |||||||||||
| Journal: | Biochem Pharmacol. 1991 Aug 8;42(5):1021-7. | ||||||||||
| Title: | High levels of expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin. | ||||||||||
| Author: | Cresteil, T|Jaiswal, A K | ||||||||||
| PMID: | 1651729 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochemistry. 1997 Nov 18;36(46):14128-36. | ||||||||||
| Title: | Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C. | ||||||||||
| Author: | Suresh Kumar, G|Lipman, R|Cummings, J|Tomasz, M | ||||||||||
| PMID: | 9369485 | ||||||||||
| 3. | |||||||||||
| Journal: | Curr Pharm Des. 2003;9(26):2091-104. | ||||||||||
| Title: | CB 1954: from the Walker tumor to NQO2 and VDEPT. | ||||||||||
| Author: | Knox, Richard J|Burke, Philip J|Chen, Shiuan|Kerr, David J | ||||||||||
| PMID: | 14529407 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Treat Rev. 2004 Aug;30(5):437-49. | ||||||||||
| Title: | DT-diaphorase: a target for new anticancer drugs. | ||||||||||
| Author: | Danson, S|Ward, T H|Butler, J|Ranson, M | ||||||||||
| PMID: | 15245776 | ||||||||||
| 5. | |||||||||||
| Journal: | J Hepatol. 2005 Apr;42(4):511-9. | ||||||||||
| Title: | Hypermethylation of NAD(P)H: quinone oxidoreductase 1 (NQO1) gene in human hepatocellular carcinoma. | ||||||||||
| Author: | Tada, Motohisa|Yokosuka, Osamu|Fukai, Kenichi|Chiba, Tetsuhiro|Imazeki, Fumio|Tokuhisa, Takeshi|Saisho, Hiromitsu | ||||||||||
| PMID: | 15763338 | ||||||||||
| 6. | |||||||||||
| Journal: | Histol Histopathol. 2009 Oct;24(10):1223-32. | ||||||||||
| Title: | Analysis of NQO1 polymorphisms and p53 protein expression in patients with hepatocellular carcinoma. | ||||||||||
| Author: | Chiu, Mei-Miao|Ko, Ying-Ju|Tsou, Ann-Ping|Chau, Gar-Yang|Chau, Yat-Pang | ||||||||||
| PMID: | 19688691 | ||||||||||
| 7. | |||||||||||
| Journal: | Arch Toxicol. 2010 Feb;84(2):155-64. | ||||||||||
| Title: | Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice. | ||||||||||
| Author: | Kawai, Masaomi|Saegusa, Yukie|Dewa, Yasuaki|Nishimura, Jihei|Kemmochi, Sayaka|Harada, Tomoaki|Ishii, Yuji|Umemura, Takashi|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 20101389 | ||||||||||
| 8. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2010;11(4):1051-8. | ||||||||||
| Title: | No association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and risk of hepatocellular carcinoma development in Turkish subjects. | ||||||||||
| Author: | Akkiz, Hikmet|Bayram, Suleyman|Bekar, Aynur|Akgollu, Ersin|Ulger, Yakup|Kaya, Berrin Yalinbas|Sandikci, Macit|Ozdil, Burhan | ||||||||||
| PMID: | 21133623 | ||||||||||
| 9. | |||||||||||
| Journal: | Arch Toxicol. 2011 Sep;85(9):1159-66. | ||||||||||
| Title: | Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats. | ||||||||||
| Author: | Shimamoto, Keisuke|Dewa, Yasuaki|Kemmochi, Sayaka|Taniai, Eriko|Hayashi, Hitomi|Imaoka, Masako|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 21203749 | ||||||||||
| 10. | |||||||||||
| Journal: | Toxicology. 2011 Apr 28;283(1):8-17. | ||||||||||
| Title: | Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by beta-naphthoflavone involving TNFalpha-signaling due to oxidative cellular stress in rats. | ||||||||||
| Author: | Kuwata, Kazunori|Shibutani, Makoto|Hayashi, Hitomi|Shimamoto, Keisuke|Hayashi, Shim-Mo|Suzuki, Kazuhiko|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 21295105 | ||||||||||
| 11. | |||||||||||
| Journal: | Free Radic Biol Med. 2011 Nov 1;51(9):1675-85. | ||||||||||
| Title: | Transcriptional modulation of the NAD(P)H:quinone oxidoreductase 1 by mercury in human hepatoma HepG2 cells. | ||||||||||
| Author: | Amara, Issa E A|El-Kadi, Ayman O S | ||||||||||
| PMID: | 21843634 | ||||||||||
| 12. | |||||||||||
| Journal: | J Toxicol Sci. 2012;37(3):517-26. | ||||||||||
| Title: | Threshold dose of liver tumor promoting effect of beta-naphthoflavone in rats. | ||||||||||
| Author: | Hayashi, Hitomi|Taniai, Eriko|Morita, Reiko|Yafune, Atsunori|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22687991 | ||||||||||
| 13. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13 Suppl:131-6. | ||||||||||
| Title: | NQO1 expression correlates with cholangiocarcinoma prognosis. | ||||||||||
| Author: | Buranrat, Benjaporn|Chau-in, Siri|Prawan, Auemduan|Puapairoj, Anucha|Zeekpudsa, Pornsilp|Kukongviriyapan, Veerapol | ||||||||||
| PMID: | 23480754 | ||||||||||
| 14. | |||||||||||
| Journal: | J Ethnopharmacol. 2012 Nov 21;144(2):416-24. | ||||||||||
| Title: | Induction of quinone oxidoreductase 1 enzyme by Rhazya stricta through Nrf2-dependent mechanism. | ||||||||||
| Author: | El Gendy, Mohamed A M|Ali, Badreldin H|Michail, Karim|Siraki, Arno G|El-Kadi, Ayman O S | ||||||||||
| PMID: | 23026305 | ||||||||||
| 15. | |||||||||||
| Journal: | J Toxicol Sci. 2012;37(3):491-501. | ||||||||||
| Title: | Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action. | ||||||||||
| Author: | Hayashi, Hitomi|Shimamoto, Keisuke|Taniai, Eriko|Ishii, Yuji|Morita, Reiko|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22687989 | ||||||||||
| 16. | |||||||||||
| Journal: | Immunol Res. 2012 Jun;52(3):258-68. | ||||||||||
| Title: | Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by biocomputation. | ||||||||||
| Author: | Wang, Lin|Huang, Juxiang|Jiang, Minghu|Lin, Hong | ||||||||||
| PMID: | 22528125 | ||||||||||
| 17. | |||||||||||
| Journal: | J Toxicol Sci. 2012;37(2):297-306. | ||||||||||
| Title: | Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action. | ||||||||||
| Author: | Hojo, Yuri|Shiraki, Ayako|Tsuchiya, Takuma|Shimamoto, Keisuke|Ishii, Yuji|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22467020 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Biol Rep. 2012 Jun;39(6):6641-6. | ||||||||||
| Title: | Interactions between CYP1A1 polymorphisms and cigarette smoking are associated with the risk of hepatocellular carcinoma: evidence from epidemiological studies. | ||||||||||
| Author: | Yu, Lei|Sun, Lei|Jiang, Yang-Fang|Lu, Bao-Ling|Sun, De-Rong|Zhu, Li-Ying | ||||||||||
| PMID: | 22297691 | ||||||||||
| 19. | |||||||||||
| Journal: | Arch Toxicol. 2012 Mar;86(3):497-507. | ||||||||||
| Title: | Mechanistic study on liver tumor promoting effects of flutamide in rats. | ||||||||||
| Author: | Tawfeeq, Mohammad Monir|Hayashi, Hitomi|Shimamoto, Keisuke|Suzuki, Kazuhiko|Shibutani, Makoto|Inokuma, Hisashi|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22076107 | ||||||||||
| 20. | |||||||||||
| Journal: | J Biomed Biotechnol. 2012;2012:782642. | ||||||||||
| Title: | Camel milk modulates the expression of aryl hydrocarbon receptor-regulated genes, Cyp1a1, Nqo1, and Gsta1, in murine hepatoma Hepa 1c1c7 cells. | ||||||||||
| Author: | Korashy, Hesham M|El Gendy, Mohamed A M|Alhaider, Abdulqader A|El-Kadi, Ayman O | ||||||||||
| PMID: | 22570534 | ||||||||||
| 21. | |||||||||||
| Journal: | Tumour Biol. 2013 Feb;34(1):47-53. | ||||||||||
| Title: | A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population. | ||||||||||
| Author: | Liu, Fei|Luo, Limei|Wei, Yonggang|Wang, Wentao|Li, Bo|Yan, Lvnan|Wen, Tianfu | ||||||||||
| PMID: | 22972504 | ||||||||||
| 22. | |||||||||||
| Journal: | Chem Res Toxicol. 2013 Feb 18;26(2):290-9. | ||||||||||
| Title: | Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I). | ||||||||||
| Author: | Stiborova, Marie|Dracinska, Helena|Martinek, Vaclav|Svaskova, Dagmar|Hodek, Petr|Milichovsky, Jan|Hejdukova, Zaneta|Brotanek, Jaroslav|Schmeiser, Heinz H|Frei, Eva | ||||||||||
| PMID: | 23289503 | ||||||||||
| 23. | |||||||||||
| Journal: | Free Radic Biol Med. 2013 Dec;65:632-644. | ||||||||||
| Title: | Epigenetic silencing of NAD(P)H:quinone oxidoreductase 1 by hepatitis B virus X protein increases mitochondrial injury and cellular susceptibility to oxidative stress in hepatoma cells. | ||||||||||
| Author: | Wu, Yun-Li|Wang, Dong|Peng, Xian-E|Chen, Yan-Ling|Zheng, Da-Li|Chen, Wan-Nan|Lin, Xu | ||||||||||
| PMID: | 23920313 | ||||||||||
| 24. | |||||||||||
| Journal: | J Toxicol Sci. 2013;38(5):679-88. | ||||||||||
| Title: | Suppressive effect of liver tumor-promoting activities in rats subjected to combined administration of phenobarbital and piperonyl butoxide. | ||||||||||
| Author: | Morita, Reiko|Yafune, Atsunori|Shiraki, Ayako|Itahashi, Megu|Akane, Hirotoshi|Nakane, Fumiyuki|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 24025784 | ||||||||||
| 25. | |||||||||||
| Journal: | J Toxicol Sci. 2014 Feb;39(1):129-40. | ||||||||||
| Title: | Modifying effects of liver tumor promotion in rats subjected to co-administration of indole-3-carbinol and phenobarbital. | ||||||||||
| Author: | Segawa, Risa|Hayashi, Hitomi|Morita, Reiko|Ogawa, Takashi|Takimoto, Norifumi|Hara, Shintaro|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 24418717 | ||||||||||
| 26. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2014 Dec 15;281(3):285-93. | ||||||||||
| Title: | Mechanistic studies of cancer cell mitochondria- and NQO1-mediated redox activation of beta-lapachone, a potentially novel anticancer agent. | ||||||||||
| Author: | Li, Jason Z|Ke, Yuebin|Misra, Hara P|Trush, Michael A|Li, Y Robert|Zhu, Hong|Jia, Zhenquan | ||||||||||
| PMID: | 25448047 | ||||||||||
| 27. | |||||||||||
| Journal: | Mol Pharm. 2015 Nov 2;12(11):3999-4010. | ||||||||||
| Title: | beta-Lapachone and Paclitaxel Combination Micelles with Improved Drug Encapsulation and Therapeutic Synergy as Novel Nanotherapeutics for NQO1-Targeted Cancer Therapy. | ||||||||||
| Author: | Zhang, Ling|Chen, Zhen|Yang, Kuan|Liu, Chun|Gao, Jinming|Qian, Feng | ||||||||||
| PMID: | 26415823 | ||||||||||
| 28. | |||||||||||
| Journal: | Hepatobiliary Pancreat Dis Int. 2015 Oct;14(5):485-91. | ||||||||||
| Title: | Liver expression of Nrf2-related genes in different liver diseases. | ||||||||||
| Author: | Cheng, Ming-Liang|Lu, Yuan-Fu|Chen, Hong|Shen, Zhong-Yang|Liu, Jie | ||||||||||
| PMID: | 26459724 | ||||||||||
| 29. | |||||||||||
| Journal: | Biochim Biophys Acta. 2016 Feb;1864(2):219-32. | ||||||||||
| Title: | Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma. | ||||||||||
| Author: | Ger, Marija|Kaupinis, Algirdas|Nemeikaite-Ceniene, Ausra|Sarlauskas, Jonas|Cicenas, Jonas|Cenas, Narimantas|Valius, Mindaugas | ||||||||||
| PMID: | 26596252 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Mol Sci. 2016 May 19;17(5). pii: ijms17050775. | ||||||||||
| Title: | Ruthenium Complexes Induce HepG2 Human Hepatocellular Carcinoma Cell Apoptosis and Inhibit Cell Migration and Invasion through Regulation of the Nrf2 Pathway. | ||||||||||
| Author: | Lu, Yiyu|Shen, Ting|Yang, Hua|Gu, Weiguang | ||||||||||
| PMID: | 27213353 | ||||||||||
| 31. | |||||||||||
| Journal: | Acta Pharm. 2016 Dec 1;66(4):491-502. | ||||||||||
| Title: | Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells. | ||||||||||
| Author: | Karakurt, Sedar | ||||||||||
| PMID: | 27749250 | ||||||||||
| 32. | |||||||||||
| Journal: | DNA Cell Biol. 2017 Apr;36(4):256-263. | ||||||||||
| Title: | Overexpression of NAD(P)H: Quinone Oxidoreductase 1 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induced Apoptosis by Activating AMPK/PGC-1alpha Pathway. | ||||||||||
| Author: | Zhang, Xin|Han, Kun|Yuan, Dong-Hong|Meng, Cun-Ying | ||||||||||
| PMID: | 28191864 | ||||||||||
| 33. | |||||||||||
| Journal: | Toxicol Sci. 2018 Jun 1;163(2):397-408. | ||||||||||
| Title: | Epalrestat Stimulated Oxidative Stress, Inflammation, and Fibrogenesis in Mouse Liver. | ||||||||||
| Author: | Le, Yuan|Chen, Liming|Zhang, Yue|Bu, Pengli|Dai, Guoli|Cheng, Xingguo | ||||||||||
| PMID: | 28204799 | ||||||||||
| 34. | |||||||||||
| Journal: | Arch Toxicol. 2018 Jun;92(6):2109-2118. | ||||||||||
| Title: | Dysregulation of autophagy in rat liver with mitochondrial DNA depletion induced by the nucleoside analogue zidovudine. | ||||||||||
| Author: | Santos-Llamas, Ana|Monte, Maria J|Marin, Jose J G|Perez, Maria J | ||||||||||
| PMID: | 29594326 | ||||||||||