Primary Site >> Liver Cancer
Gene >> NOX4
| 1. | |||||||||||
| Journal: | J Hepatol. 2008 Dec;49(6):965-76. | ||||||||||
| Title: | Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity. | ||||||||||
| Author: | Carmona-Cuenca, Irene|Roncero, Cesar|Sancho, Patricia|Caja, Laia|Fausto, Nelson|Fernandez, Margarita|Fabregat, Isabel | ||||||||||
| PMID: | 18845355 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Pharmacol. 2008 May 15;75(10):1935-45. | ||||||||||
| Title: | Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion. | ||||||||||
| Author: | Ortiz, Conrad|Caja, Laia|Sancho, Patricia|Bertran, Esther|Fabregat, Isabel | ||||||||||
| PMID: | 18371937 | ||||||||||
| 3. | |||||||||||
| Journal: | Carcinogenesis. 2009 Jul;30(7):1106-14. | ||||||||||
| Title: | Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells. | ||||||||||
| Author: | Song, In-Sung|Kim, Sun-Uk|Oh, Nang-Su|Kim, Jiyoung|Yu, Dae-Yeul|Huang, Song Mei|Kim, Jin-Man|Lee, Dong-Seok|Kim, Nam-Soon | ||||||||||
| PMID: | 19406930 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2009 Oct 1;69(19):7595-602. | ||||||||||
| Title: | Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4. | ||||||||||
| Author: | Caja, Laia|Sancho, Patricia|Bertran, Esther|Iglesias-Serret, Daniel|Gil, Joan|Fabregat, Isabel | ||||||||||
| PMID: | 19773433 | ||||||||||
| 5. | |||||||||||
| Journal: | Hepatology. 2010 Sep;52(3):966-74. | ||||||||||
| Title: | Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth. | ||||||||||
| Author: | Senturk, Serif|Mumcuoglu, Mine|Gursoy-Yuzugullu, Ozge|Cingoz, Burcu|Akcali, Kamil Can|Ozturk, Mehmet | ||||||||||
| PMID: | 20583212 | ||||||||||
| 6. | |||||||||||
| Journal: | J Mol Endocrinol. 2010 Dec;45(6):379-90. | ||||||||||
| Title: | Testosterone-induced permanent changes of hepatic gene expression in female mice sustained during Plasmodium chabaudi malaria infection. | ||||||||||
| Author: | Delic, Denis|Gailus, Nicole|Vohr, Hans-Werner|Dkhil, Mohamed|Al-Quraishy, Saleh|Wunderlich, Frank | ||||||||||
| PMID: | 20844152 | ||||||||||
| 7. | |||||||||||
| Journal: | J Hepatol. 2011 Aug;55(2):351-8. | ||||||||||
| Title: | Dissecting the effect of targeting the epidermal growth factor receptor on TGF-beta-induced-apoptosis in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Caja, Laia|Sancho, Patricia|Bertran, Esther|Fabregat, Isabel | ||||||||||
| PMID: | 21147185 | ||||||||||
| 8. | |||||||||||
| Journal: | Tumour Biol. 2011 Dec;32(6):1173-82. | ||||||||||
| Title: | NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy. | ||||||||||
| Author: | Lu, Can-Liang|Qiu, Ji-Liang|Huang, Pin-Zhu|Zou, Ru-Hai|Hong, Jian|Li, Bin-Kui|Chen, Gui-Hua|Yuan, Yun-Fei | ||||||||||
| PMID: | 21915726 | ||||||||||
| 9. | |||||||||||
| Journal: | Hepatology. 2012 Dec;56(6):2375-86. | ||||||||||
| Title: | The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice. | ||||||||||
| Author: | Yu, Ji Hoon|Zhu, Bing-Mei|Riedlinger, Gregory|Kang, Keunsoo|Hennighausen, Lothar | ||||||||||
| PMID: | 22711600 | ||||||||||
| 10. | |||||||||||
| Journal: | Free Radic Biol Med. 2014 Apr;69:338-47. | ||||||||||
| Title: | The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression. | ||||||||||
| Author: | Crosas-Molist, Eva|Bertran, Esther|Sancho, Patricia|Lopez-Luque, Judit|Fernando, Joan|Sanchez, Aranzazu|Fernandez, Margarita|Navarro, Estanis|Fabregat, Isabel | ||||||||||
| PMID: | 24509161 | ||||||||||
| 11. | |||||||||||
| Journal: | Free Radic Biol Med. 2014 Jul;72:267-84. | ||||||||||
| Title: | Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma. | ||||||||||
| Author: | Choi, Jinah|Corder, Nicole L B|Koduru, Bhargav|Wang, Yiyan | ||||||||||
| PMID: | 24816297 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Med Rep. 2015 Mar;11(3):1609-14. | ||||||||||
| Title: | Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-beta pathway. | ||||||||||
| Author: | Liu, Bin|Zhou, Wei|Chen, Xiaofeng|Xu, Fengming|Chen, Yinqin|Liu, Jie|Zhang, Qingyu|Bao, Shiting|Chen, Nianping|Li, Mingyi|Zhu, Runzhi | ||||||||||
| PMID: | 25376731 | ||||||||||
| 13. | |||||||||||
| Journal: | Biomed Res Int. 2015;2015:491205. | ||||||||||
| Title: | {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acet ic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3. | ||||||||||
| Author: | Li, Ye|Wang, Wenjing|Xu, Xiaoxue|Sun, Shiyue|Xu, Xiaoyu|Qu, Xian-jun | ||||||||||
| PMID: | 25961022 | ||||||||||
| 14. | |||||||||||
| Journal: | Free Radic Biol Med. 2015 Jul;84:54-64. | ||||||||||
| Title: | Transforming growth factor beta-interacting factor-induced malignant progression of hepatocellular carcinoma cells depends on superoxide production from Nox4. | ||||||||||
| Author: | Liu, Zi-Miao|Tseng, Hong-Yu|Tsai, Hung-Wen|Su, Fang-Cheng|Huang, Huei-Sheng | ||||||||||
| PMID: | 25841779 | ||||||||||
| 15. | |||||||||||
| Journal: | Gut Liver. 2016 Sep 15;10(5):826-35. | ||||||||||
| Title: | NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy. | ||||||||||
| Author: | Ha, Sang Yun|Paik, Yong-Han|Yang, Jung Wook|Lee, Min Ju|Bae, Hyunsik|Park, Cheol-Keun | ||||||||||
| PMID: | 27282266 | ||||||||||
| 16. | |||||||||||
| Journal: | J Mol Med (Berl). 2016 Oct;94(10):1153-1166. | ||||||||||
| Title: | Differential transcriptional regulation of hypoxia-inducible factor-1alpha by arsenite under normoxia and hypoxia: involvement of Nrf2. | ||||||||||
| Author: | Al Taleb, Zukaa|Petry, Andreas|Chi, Tabughang Franklin|Mennerich, Daniela|Gorlach, Agnes|Dimova, Elitsa Y|Kietzmann, Thomas | ||||||||||
| PMID: | 27286880 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncogene. 2017 May 25;36(21):3002-3014. | ||||||||||
| Title: | The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. | ||||||||||
| Author: | Crosas-Molist, E|Bertran, E|Rodriguez-Hernandez, I|Herraiz, C|Cantelli, G|Fabra, A|Sanz-Moreno, V|Fabregat, I | ||||||||||
| PMID: | 27941881 | ||||||||||
| 18. | |||||||||||
| Journal: | Sci Rep. 2017 Sep 11;7(1):11060. | ||||||||||
| Title: | Gene expression of NOX family members and their clinical significance in hepatocellular carcinoma. | ||||||||||
| Author: | Eun, Hyuk Soo|Cho, Sang Yeon|Joo, Jong Seok|Kang, Sun Hyung|Moon, Hee Seok|Lee, Eaum Seok|Kim, Seok Hyun|Lee, Byung Seok | ||||||||||
| PMID: | 28894215 | ||||||||||
| 19. | |||||||||||
| Journal: | Cell Death Dis. 2017 Oct 12;8(10):e3098. | ||||||||||
| Title: | The level of caveolin-1 expression determines response to TGF-beta as a tumour suppressor in hepatocellular carcinoma cells. | ||||||||||
| Author: | Moreno-Caceres, Joaquim|Caballero-Diaz, Daniel|Nwosu, Zeribe Chike|Meyer, Christoph|Lopez-Luque, Judit|Malfettone, Andrea|Lastra, Raquel|Serrano, Teresa|Ramos, Emilio|Dooley, Steven|Fabregat, Isabel | ||||||||||
| PMID: | 29022911 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancers (Basel). 2017 Oct 25;9(11). pii: cancers9110145. | ||||||||||
| Title: | Does Hypoxia Cause Carcinogenic Iron Accumulation in Alcoholic Liver Disease (ALD)? | ||||||||||
| Author: | Silva, Ines|Rausch, Vanessa|Seitz, Helmut-Karl|Mueller, Sebastian | ||||||||||
| PMID: | 29068390 | ||||||||||
| 21. | |||||||||||
| Journal: | Sci Rep. 2017 Oct 30;7(1):14346. | ||||||||||
| Title: | NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4. | ||||||||||
| Author: | Singh, Anand|Koduru, Bhargav|Carlisle, Cameron|Akhter, Hasina|Liu, Rui-Ming|Schroder, Katrin|Brandes, Ralf P|Ojcius, David M | ||||||||||
| PMID: | 29085012 | ||||||||||
| 22. | |||||||||||
| Journal: | Cell Physiol Biochem. 2017;44(5):1856-1868. | ||||||||||
| Title: | Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling. | ||||||||||
| Author: | Liu, Zhikui|Tu, Kangsheng|Wang, Yufeng|Yao, Bowen|Li, Qing|Wang, Liang|Dou, Changwei|Liu, Qingguang|Zheng, Xin | ||||||||||
| PMID: | 29237157 | ||||||||||
| 23. | |||||||||||
| Journal: | Antiviral Res. 2018 Feb;150:47-59. | ||||||||||
| Title: | A natural small molecule inhibitor corilagin blocks HCV replication and modulates oxidative stress to reduce liver damage. | ||||||||||
| Author: | Reddy, B Uma|Mullick, Ranajoy|Kumar, Anuj|Sharma, Geetika|Bag, Paromita|Roy, Chaitrali Laha|Sudha, Govindarajan|Tandon, Himani|Dave, Pratik|Shukla, Ashutosh|Srinivasan, Priyanka|Nandhitha, Madhusudhan|Srinivasan, Narayanaswamy|Das, Saumitra | ||||||||||
| PMID: | 29224736 | ||||||||||