Primary Site >> Liver Cancer
Gene >> NOTCH3
| 1. | |||||||||||
| Journal: | Anticancer Res. 2006 May-Jun;26(3A):2123-7. | ||||||||||
| Title: | Notch3 intracellular domain accumulates in HepG2 cell line. | ||||||||||
| Author: | Giovannini, Catia|Lacchini, Michela|Gramantieri, Laura|Chieco, Pasquale|Bolondi, Luigi | ||||||||||
| PMID: | 16827154 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 2007 Apr;45(4):957-67. | ||||||||||
| Title: | Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor. | ||||||||||
| Author: | Cerec, Virginie|Glaise, Denise|Garnier, Delphine|Morosan, Serban|Turlin, Bruno|Drenou, Bernard|Gripon, Philippe|Kremsdorf, Dina|Guguen-Guillouzo, Christiane|Corlu, Anne | ||||||||||
| PMID: | 17393521 | ||||||||||
| 3. | |||||||||||
| Journal: | Liver Int. 2007 Sep;27(7):997-1007. | ||||||||||
| Title: | Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma. | ||||||||||
| Author: | Gramantieri, Laura|Giovannini, Catia|Lanzi, Arianna|Chieco, Pasquale|Ravaioli, Matteo|Venturi, Annamaria|Grazi, Gian Luca|Bolondi, Luigi | ||||||||||
| PMID: | 17696940 | ||||||||||
| 4. | |||||||||||
| Journal: | Dig Liver Dis. 2008 Feb;40(2):114-21. | ||||||||||
| Title: | Deregulated expression of Notch receptors in human hepatocellular carcinoma. | ||||||||||
| Author: | Gao, J|Song, Z|Chen, Y|Xia, L|Wang, J|Fan, R|Du, R|Zhang, F|Hong, L|Song, J|Zou, X|Xu, H|Zheng, G|Liu, J|Fan, D | ||||||||||
| PMID: | 17920003 | ||||||||||
| 5. | |||||||||||
| Journal: | J Hepatol. 2009 May;50(5):969-79. | ||||||||||
| Title: | Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism. | ||||||||||
| Author: | Giovannini, Catia|Gramantieri, Laura|Chieco, Pasquale|Minguzzi, Manuela|Lago, Federica|Pianetti, Simona|Ramazzotti, Eric|Marcu, Kenneth B|Bolondi, Luigi | ||||||||||
| PMID: | 19304334 | ||||||||||
| 6. | |||||||||||
| Journal: | Stem Cells Dev. 2011 Oct;20(10):1687-99. | ||||||||||
| Title: | The epigenetic regulation of stem cell factors in hepatic stellate cells. | ||||||||||
| Author: | Reister, Sven|Kordes, Claus|Sawitza, Iris|Haussinger, Dieter | ||||||||||
| PMID: | 21219128 | ||||||||||
| 7. | |||||||||||
| Journal: | Am J Pathol. 2012 Aug;181(2):413-22. | ||||||||||
| Title: | CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma. | ||||||||||
| Author: | Giovannini, Catia|Gramantieri, Laura|Minguzzi, Manuela|Fornari, Francesca|Chieco, Pasquale|Grazi, Gian Luca|Bolondi, Luigi | ||||||||||
| PMID: | 22705236 | ||||||||||
| 8. | |||||||||||
| Journal: | Integr Biol (Camb). 2012 Oct;4(10):1256-62. | ||||||||||
| Title: | Inhibited PTHLH downstream leukocyte adhesion-mediated protein amino acid N-linked glycosylation coupling Notch and JAK-STAT cascade to iron-sulfur cluster assembly-induced aging network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by sy | ||||||||||
| Author: | Wang, Lin|Huang, Juxiang|Jiang, Minghu|Lin, Hong|Qi, Lianxiu|Diao, Haizhen | ||||||||||
| PMID: | 22955522 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncol Lett. 2013 Mar;5(3):1075-1079. | ||||||||||
| Title: | Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation. | ||||||||||
| Author: | Qi, Lianxiu|Wang, Lin|Huang, Juxiang|Jiang, Minghu|Diao, Haizhen|Zhou, Huilei|Li, Xiaohe|Jiang, Zhenfu | ||||||||||
| PMID: | 23426651 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2013;8(2):e57382. | ||||||||||
| Title: | The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma. | ||||||||||
| Author: | Zhou, Liang|Zhang, Ning|Song, Wenjie|You, Nan|Li, Qingjun|Sun, Wei|Zhang, Yong|Wang, Desheng|Dou, Kefeng | ||||||||||
| PMID: | 23468978 | ||||||||||
| 11. | |||||||||||
| Journal: | Hepatobiliary Pancreat Dis Int. 2013 Jun;12(3):286-94. | ||||||||||
| Title: | Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Ahn, Soomin|Hyeon, Jiyeon|Park, Cheol-Keun | ||||||||||
| PMID: | 23742774 | ||||||||||
| 12. | |||||||||||
| Journal: | Dig Liver Dis. 2013 Oct;45(10):844-51. | ||||||||||
| Title: | C/EBPalpha inhibits hepatocellular carcinoma by reducing Notch3/Hes1/p27 cascades. | ||||||||||
| Author: | Shi, Yi-Chao|Zhao, Hong|Yin, Chuan|Zeng, Xin|Zhang, Qing|Xu, Wen-Ping|Wei, Ji|Chen, Fei|Xie, Wei-Fen | ||||||||||
| PMID: | 23816696 | ||||||||||
| 13. | |||||||||||
| Journal: | Biosci Trends. 2013 Jun;7(3):152-6. | ||||||||||
| Title: | Aberrant expression of Notch3 predicts poor survival for hepatocellular carcinomas. | ||||||||||
| Author: | Hu, Lei|Xue, Feng|Shao, Minhua|Deng, Anmei|Wei, Gongtian | ||||||||||
| PMID: | 23836039 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2013 Oct;4(10):1618-31. | ||||||||||
| Title: | Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma. | ||||||||||
| Author: | Giovannini, Catia|Baglioni, Michele|Baron Toaldo, Marco|Ventrucci, Cristiano|D'Adamo, Stefania|Cipone, Mario|Chieco, Pasquale|Gramantieri, Laura|Bolondi, Luigi | ||||||||||
| PMID: | 24113128 | ||||||||||
| 15. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2014 May;22(5):354-7. | ||||||||||
| Title: | [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells]. | ||||||||||
| Author: | Li, Jianfang|Ding, Shixiong|Ying, Liping|Hu, Airong|Hu, Yaoren|Liang, Xiaoyue | ||||||||||
| PMID: | 25180870 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncotarget. 2014 Nov 15;5(21):10607-20. | ||||||||||
| Title: | Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. | ||||||||||
| Author: | Giovannini, Catia|Minguzzi, Manuela|Baglioni, Michele|Fornari, Francesca|Giannone, Ferdinando|Ravaioli, Matteo|Cescon, Matteo|Chieco, Pasquale|Bolondi, Luigi|Gramantieri, Laura | ||||||||||
| PMID: | 25431954 | ||||||||||
| 17. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2014 May 15;7(6):3272-9. eCollection 2014. | ||||||||||
| Title: | Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Wu, Wen-Rui|Shi, Xiang-De|Zhang, Rui|Zhu, Man-Sheng|Xu, Lei-Bo|Yu, Xian-Huan|Zeng, Hong|Wang, Jie|Liu, Chao | ||||||||||
| PMID: | 25031748 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Mol Med. 2014 Aug;34(2):420-8. | ||||||||||
| Title: | MicroRNA-206 overexpression promotes apoptosis, induces cell cycle arrest and inhibits the migration of human hepatocellular carcinoma HepG2 cells. | ||||||||||
| Author: | Liu, Weiwei|Xu, Chuanming|Wan, Huifang|Liu, Chunju|Wen, Can|Lu, Hongfei|Wan, Fusheng | ||||||||||
| PMID: | 24919811 | ||||||||||
| 19. | |||||||||||
| Journal: | Hepatology. 2015 Mar;61(3):942-52. | ||||||||||
| Title: | Differential effects of targeting Notch receptors in a mouse model of liver cancer. | ||||||||||
| Author: | Huntzicker, Erik G|Hotzel, Kathy|Choy, Lisa|Che, Li|Ross, Jed|Pau, Gregoire|Sharma, Neeraj|Siebel, Christian W|Chen, Xin|French, Dorothy M | ||||||||||
| PMID: | 25311838 | ||||||||||
| 20. | |||||||||||
| Journal: | Hepatology. 2015 Jun;61(6):1945-56. | ||||||||||
| Title: | DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma. | ||||||||||
| Author: | Villanueva, Augusto|Portela, Anna|Sayols, Sergi|Battiston, Carlo|Hoshida, Yujin|Mendez-Gonzalez, Jesus|Imbeaud, Sandrine|Letouze, Eric|Hernandez-Gea, Virginia|Cornella, Helena|Pinyol, Roser|Sole, Manel|Fuster, Josep|Zucman-Rossi, Jessica|Mazzaferro, Vince | ||||||||||
| PMID: | 25645722 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2015 Feb 28;6(6):3669-79. | ||||||||||
| Title: | Notch3 functions as a regulator of cell self-renewal by interacting with the beta-catenin pathway in hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Qingyu|Lu, Caijie|Fang, Tao|Wang, Yongcun|Hu, Wenhua|Qiao, Jie|Liu, Bin|Liu, Jie|Chen, Nianping|Li, Mingyi|Zhu, Runzhi | ||||||||||
| PMID: | 25668819 | ||||||||||
| 22. | |||||||||||
| Journal: | Nat Commun. 2015 Sep 30;6:8271. | ||||||||||
| Title: | PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells. | ||||||||||
| Author: | Han, Haibo|Du, Yantao|Zhao, Wei|Li, Sheng|Chen, Dongji|Zhang, Jing|Liu, Jiang|Suo, Zhenhe|Bian, Xiuwu|Xing, Baocai|Zhang, Zhiqian | ||||||||||
| PMID: | 26420065 | ||||||||||
| 23. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2016 Mar 20;24(3):202-6. | ||||||||||
| Title: | [Extracellular Y-box binding protein-1 promotes proliferation and metastasis of HepG2 cells through Notch3 receptor]. | ||||||||||
| Author: | Shi, J|Li, P|Zou, L|Chen, P|Zhang, L P | ||||||||||
| PMID: | 27095764 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Mol Sci. 2016 Dec 28;18(1). pii: ijms18010056. | ||||||||||
| Title: | Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives. | ||||||||||
| Author: | Giovannini, Catia|Bolondi, Luigi|Gramantieri, Laura | ||||||||||
| PMID: | 28036048 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncol Lett. 2016 Dec;12(6):5122-5128. | ||||||||||
| Title: | Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-kappaB pathway in HepG2 cells. | ||||||||||
| Author: | Qiao, Jie|Liu, Jie|Jia, Kaiqiao|Li, Ning|Liu, Bin|Zhang, Qingyu|Zhu, Runzhi | ||||||||||
| PMID: | 28101238 | ||||||||||
| 26. | |||||||||||
| Journal: | EXCLI J. 2016 Nov 11;15:687-698. | ||||||||||
| Title: | Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis. | ||||||||||
| Author: | Bogaerts, Eliene|Paridaens, Annelies|Verhelst, Xavier|Carmeliet, Peter|Geerts, Anja|Van Vlierberghe, Hans|Devisscher, Lindsey | ||||||||||
| PMID: | 28337100 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncol Rep. 2017 Jan;37(1):348-356. | ||||||||||
| Title: | Hepatitis B virus X protein and hypoxiainducible factor-1alpha stimulate Notch gene expression in liver cancer cells. | ||||||||||
| Author: | Yang, Sheng-Li|Ren, Quan-Guang|Zhang, Tao|Pan, Xiaoli|Wen, Lu|Hu, Jian-Li|Yu, Chao|He, Qian-Jin | ||||||||||
| PMID: | 27840976 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Med. 2017 Jul;6(7):1587-1600. | ||||||||||
| Title: | Prognostic value of Notch receptors in postsurgical patients with hepatitis B virus-related hepatocellular carcinoma. | ||||||||||
| Author: | Yu, Tingdong|Han, Chuangye|Zhu, Guangzhi|Liao, Xiwen|Qin, Wei|Yang, Chengkun|Liu, Zhen|Su, Hao|Liu, Xiaoguang|Yu, Long|Liu, Zhengtao|Lu, Sicong|Chen, Zhiwei|Liang, Yu|Huang, Jianlu|Qin, Xue|Gui, Ying|Li, Jiaquan|Peng, Tao | ||||||||||
| PMID: | 28568708 | ||||||||||
| 29. | |||||||||||
| Journal: | Int J Oncol. 2017 Oct;51(4):1135-1145. | ||||||||||
| Title: | Expression of Wnt3a in hepatocellular carcinoma and its effects on cell cycle and metastasis. | ||||||||||
| Author: | Lu, Caijie|He, Yifeng|Duan, Juan|Yang, Yongguang|Zhong, Chunqiang|Zhang, Jian|Liao, Weiguo|Huang, Xiaojie|Zhu, Runzhi|Li, Mingyi | ||||||||||
| PMID: | 28902357 | ||||||||||
| 30. | |||||||||||
| Journal: | Am J Cancer Res. 2017 Dec 1;7(12):2503-2514. eCollection 2017. | ||||||||||
| Title: | Combination of sorafenib and Valproic acid synergistically induces cell apoptosis and inhibits hepatocellular carcinoma growth via down-regulating Notch3 and pAkt. | ||||||||||
| Author: | Zhu, Wanhu|Liang, Qing|Yang, Xu|Yu, Yan|Shen, Xiaoying|Sun, Guangchun | ||||||||||
| PMID: | 29312803 | ||||||||||
| 31. | |||||||||||
| Journal: | Surgery. 2018 Jan;163(1):104-111. | ||||||||||
| Title: | Notch3 as a novel therapeutic target in metastatic medullary thyroid cancer. | ||||||||||
| Author: | Lou, Irene|Odorico, Scott|Yu, Xiao-Min|Harrison, April|Jaskula-Sztul, Renata|Chen, Herbert | ||||||||||
| PMID: | 29128180 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Res. 2018 Feb 15;78(4):938-949. | ||||||||||
| Title: | LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem-like Cells. | ||||||||||
| Author: | Liu, Chungang|Liu, Limei|Chen, Xuejiao|Cheng, Jiamin|Zhang, Heng|Zhang, Chengcheng|Shan, Juanjuan|Shen, Junjie|Qian, Cheng | ||||||||||
| PMID: | 29259010 | ||||||||||