Primary Site >> Liver Cancer
Gene >> NOTCH3
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Notch3 intracellular domain accumulates in HepG2 cell line. PMID: 16827154 |
Ref: Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor. PMID: 17393521 Ref: Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma. PMID: 17696940 |
Ref: Deregulated expression of Notch receptors in human hepatocellular carcinoma. PMID: 17920003 |
Ref: Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism. PMID: 19304334 |
Ref: The epigenetic regulation of stem cell factors in hepatic stellate cells. PMID: 21219128 |
Ref: CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma. PMID: 22705236 Ref: Inhibited PTHLH downstream leukocyte adhesion-mediated protein amino acid N-linked glycosylation coupling Notch and JAK-STAT cascade to iron-sulfur cluster assembly-induced aging network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by sy PMID: 22955522 |
Ref: Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation. PMID: 23426651 Ref: The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma. PMID: 23468978 Ref: Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma. PMID: 23742774 Ref: C/EBPalpha inhibits hepatocellular carcinoma by reducing Notch3/Hes1/p27 cascades. PMID: 23816696 Ref: Aberrant expression of Notch3 predicts poor survival for hepatocellular carcinomas. PMID: 23836039 Ref: Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma. PMID: 24113128 |
Ref: MicroRNA-206 overexpression promotes apoptosis, induces cell cycle arrest and inhibits the migration of human hepatocellular carcinoma HepG2 cells. PMID: 24919811 Ref: Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma. PMID: 25031748 Ref: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells]. PMID: 25180870 Ref: Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. PMID: 25431954 |
Ref: Differential effects of targeting Notch receptors in a mouse model of liver cancer. PMID: 25311838 Ref: DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma. PMID: 25645722 Ref: Notch3 functions as a regulator of cell self-renewal by interacting with the beta-catenin pathway in hepatocellular carcinoma. PMID: 25668819 Ref: PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells. PMID: 26420065 |
Ref: [Extracellular Y-box binding protein-1 promotes proliferation and metastasis of HepG2 cells through Notch3 receptor]. PMID: 27095764 Ref: Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives. PMID: 28036048 Ref: Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-kappaB pathway in HepG2 cells. PMID: 28101238 Ref: Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis. PMID: 28337100 |
Ref: Hepatitis B virus X protein and hypoxiainducible factor-1alpha stimulate Notch gene expression in liver cancer cells. PMID: 27840976 Ref: Prognostic value of Notch receptors in postsurgical patients with hepatitis B virus-related hepatocellular carcinoma. PMID: 28568708 Ref: Expression of Wnt3a in hepatocellular carcinoma and its effects on cell cycle and metastasis. PMID: 28902357 Ref: Combination of sorafenib and Valproic acid synergistically induces cell apoptosis and inhibits hepatocellular carcinoma growth via down-regulating Notch3 and pAkt. PMID: 29312803 |
Ref: Notch3 as a novel therapeutic target in metastatic medullary thyroid cancer. PMID: 29128180 Ref: LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem-like Cells. PMID: 29259010 |