Literatures

Primary Site >> Liver Cancer

Gene >> NOTCH1

1.
Journal:	Cancer Res. 2003 Dec 1;63(23):8323-9.
Title:	Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.
Author:	Qi, Runzi\|An, Huazhang\|Yu, Yizhi\|Zhang, Minghui\|Liu, Shuxun\|Xu, Hongmei\|Guo, Zhenghong\|Cheng, Tao\|Cao, Xuetao
PMID:	14678992

2.
Journal:	Dig Liver Dis. 2008 Feb;40(2):114-21.
Title:	Deregulated expression of Notch receptors in human hepatocellular carcinoma.
Author:	Gao, J\|Song, Z\|Chen, Y\|Xia, L\|Wang, J\|Fan, R\|Du, R\|Zhang, F\|Hong, L\|Song, J\|Zou, X\|Xu, H\|Zheng, G\|Liu, J\|Fan, D
PMID:	17920003

3.
Journal:	Anticancer Drugs. 2008 Jun;19(5):477-86.
Title:	Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling.
Author:	Suwanjunee, Saipin\|Wongchana, Wipawee\|Palaga, Tanapat
PMID:	18418214

4.
Journal:	Mol Carcinog. 2009 Jun;48(6):479-87.
Title:	Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet.
Author:	Tryndyak, Volodymyr P\|Ross, Sharon A\|Beland, Frederick A\|Pogribny, Igor P
PMID:	18942116

5.
Journal:	J Hepatol. 2009 May;50(5):969-79.
Title:	Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism.
Author:	Giovannini, Catia\|Gramantieri, Laura\|Chieco, Pasquale\|Minguzzi, Manuela\|Lago, Federica\|Pianetti, Simona\|Ramazzotti, Eric\|Marcu, Kenneth B\|Bolondi, Luigi
PMID:	19304334

6.
Journal:	J Biol Chem. 2009 Jun 12;284(24):16183-90.
Title:	Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression.
Author:	Wang, Chunmei\|Qi, Runzi\|Li, Nan\|Wang, Zhengxin\|An, Huazhang\|Zhang, Qinghua\|Yu, Yizhi\|Cao, Xuetao
PMID:	19376776

7.
Journal:	Neoplasma. 2009;56(6):533-41.
Title:	Expression of Notch1, Jagged1 and beta-catenin and their clinicopathological significance in hepatocellular carcinoma.
Author:	Wang, M\|Xue, L\|Cao, Q\|Lin, Y\|Ding, Y\|Yang, P\|Che, L
PMID:	19728763

8.
Journal:	Am J Transl Res. 2009 Jul 10;1(4):358-66.
Title:	Down-regulation of Notch1 signaling inhibits tumor growth in human hepatocellular carcinoma.
Author:	Ning, Li\|Wentworth, Lucy\|Chen, Herbert\|Weber, Sharon M
PMID:	19956448

9.
Journal:	Exp Cell Res. 2010 Jan 15;316(2):149-57.
Title:	RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells.
Author:	Gao, Juan\|Chen, Yu\|Wu, Kai-Chun\|Liu, Jie\|Zhao, Yan-Qiu\|Pan, Yang-Lin\|Du, Rui\|Zheng, Guo-Rong\|Xiong, Yi-Min\|Xu, Hua-Lin\|Fan, Dai-Ming
PMID:	19800882

10.
Journal:	Hepatology. 2010 Jul;52(1):142-54.
Title:	Hepatitis B virus X protein blunts senescence-like growth arrest of human hepatocellular carcinoma by reducing Notch1 cleavage.
Author:	Xu, Jiejie\|Yun, Xiaojing\|Jiang, Jianhai\|Wei, Yuanyan\|Wu, Yihong\|Zhang, Wei\|Liu, Yeheng\|Wang, Wenzhong\|Wen, Yumei\|Gu, Jianxin
PMID:	20578140

11.
Journal:	Stem Cells Dev. 2011 Oct;20(10):1687-99.
Title:	The epigenetic regulation of stem cell factors in hepatic stellate cells.
Author:	Reister, Sven\|Kordes, Claus\|Sawitza, Iris\|Haussinger, Dieter
PMID:	21219128

12.
Journal:	Hepatology. 2011 Apr;53(4):1352-62.
Title:	Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma.
Author:	Lim, Seung-Oe\|Park, Young Min\|Kim, Hyeon Seop\|Quan, Xiaoyuan\|Yoo, Jeong Eun\|Park, Young Nyun\|Choi, Gi Hong\|Jung, Guhung
PMID:	21480340

13.
Journal:	World J Gastroenterol. 2011 Aug 7;17(29):3420-30.
Title:	Late SV40 factor: a key mediator of Notch signaling in human hepatocarcinogenesis.
Author:	Fan, Ren-Hua\|Li, Jing\|Wu, Nan\|Chen, Ping-Sheng
PMID:	21876634

14.
Journal:	J Mol Histol. 2011 Oct;42(5):473-81.
Title:	Cooperation of deregulated Notch signaling and Ras pathway in human hepatocarcinogenesis.
Author:	Fan, Renhua\|Chen, Pingsheng\|Zhao, Di\|Tong, Jing Long\|Li, Jing\|Liu, Feng
PMID:	21892768

15.
Journal:	BMC Biol. 2011 Nov 30;9:83.
Title:	Notch1 binds and induces degradation of Snail in hepatocellular carcinoma.
Author:	Lim, Seung-Oe\|Kim, Hyeon Seop\|Quan, Xiaoyuan\|Ahn, Sun-Min\|Kim, Hongtae\|Hsieh, David\|Seong, Je Kyung\|Jung, Guhung
PMID:	22128911

16.
Journal:	Int J Cancer. 2012 Aug 1;131(3):E163-72.
Title:	Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma.
Author:	Wang, Xiao Qi\|Zhang, Wu\|Lui, Eric L H\|Zhu, Yongqiang\|Lu, Ping\|Yu, Xiaoming\|Sun, Jisan\|Yang, Sitian\|Poon, Ronnie T P\|Fan, Sheung Tat
PMID:	22052196

17.
Journal:	Mol Cell. 2012 Jan 27;45(2):171-84.
Title:	IKKalpha activation of NOTCH links tumorigenesis via FOXA2 suppression.
Author:	Liu, Mo\|Lee, Dung-Fang\|Chen, Chun-Te\|Yen, Chia-Jui\|Li, Long-Yuan\|Lee, Hong-Jen\|Chang, Chun-Ju\|Chang, Wei-Chao\|Hsu, Jung-Mao\|Kuo, Hsu-Ping\|Xia, Weiya\|Wei, Yongkun\|Chiu, Pei-Chun\|Chou, Chao-Kai\|Du, Yi\|Dhar, Debanjan\|Karin, Michael\|Chen, Chung-Hsuan\|Hung, Mi
PMID:	22196886

18.
Journal:	Korean J Hepatol. 2012 Mar;18(1):63-74.
Title:	Co-expression patterns of Notch1, Snail, and p53 in grade III hepatocellular carcinoma with postoperative recurrence: a preliminary study.
Author:	Jang, Sun Kyung\|Choi, Gi Hong\|Choi, Junjeong\|Quan, Xiaoyuan\|Jang, Jeong Won\|Kim, Bo Hyun\|Jung, Guhung\|Park, Young Min
PMID:	22511905

19.
Journal:	Biochem Pharmacol. 2012 Aug 15;84(4):507-12.
Title:	beta,beta-Dimethylacrylshikonin exerts antitumor activity via Notch-1 signaling pathway in vitro and in vivo.
Author:	Zhen-Jun, Shao\|Yuan-Yuan, Zhang\|Ying-Ying, Fan\|Shao-Ju, Jin\|Jiao, Yan\|Xiao-Wei, Zheng\|Jian, Chen\|Yao, Xiong\|Li-Ming, Zhou
PMID:	22634048

20.
Journal:	Am J Pathol. 2012 Aug;181(2):413-22.
Title:	CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.
Author:	Giovannini, Catia\|Gramantieri, Laura\|Minguzzi, Manuela\|Fornari, Francesca\|Chieco, Pasquale\|Grazi, Gian Luca\|Bolondi, Luigi
PMID:	22705236

21.
Journal:	Int J Oncol. 2012 Nov;41(5):1773-81.
Title:	Notch1 activation contributes to tumor cell growth and proliferation in human hepatocellular carcinoma HepG2 and SMMC7721 cells.
Author:	Gao, Juan\|Dong, Yongqiang\|Zhang, Bicheng\|Xiong, Yimin\|Xu, Weitian\|Cheng, Yi\|Dai, Meng\|Yu, Zhao\|Xu, Hualin\|Zheng, Guorong
PMID:	22922832

22.
Journal:	Gastroenterology. 2012 Dec;143(6):1660-1669.e7.
Title:	Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice.
Author:	Villanueva, Augusto\|Alsinet, Clara\|Yanger, Kilangsungla\|Hoshida, Yujin\|Zong, Yiwei\|Toffanin, Sara\|Rodriguez-Carunchio, Leonardo\|Sole, Manel\|Thung, Swan\|Stanger, Ben Z\|Llovet, Josep M
PMID:	22974708

23.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2012 Aug;20(8):628-9.
Title:	[Expression and clinical significance of Notch1 in human hepatocellular carcinoma].
Author:	Mi, Li-li\|Yin, Fei\|Du, Shao-bo\|Yao, Shu-kun
PMID:	23227533

24.
Journal:	Clin Transl Gastroenterol. 2012 Oct 4;3:e23.
Title:	Analysis of Notch and TGF-beta Signaling Expression in Different Stages of Disease Progression During Hepatitis B Virus Infection.
Author:	Trehanpati, Nirupama\|Shrivastav, Shikha\|Shivakumar, Bhavana\|Khosla, Ritu\|Bhardwaj, Suvercha\|Chaturvedi, Jaya\|Sukriti\|Kumar, Binayak\|Bose, Sujoy\|Mani Tripathi, Dinesh\|Das, Trinath\|Sakhuja, Puja\|Rastogi, Archana\|Bhihari, Chagan\|Singh, Shivender\|Gupta, Subha
PMID:	23238065

25.
Journal:	Biotechnol Lett. 2013 Jan;35(1):29-37.
Title:	Notch1 signaling contributes to the oncogenic effect of HBx on human hepatic cells.
Author:	Wang, Fan\|Xia, Xiumei\|Wang, Jinling\|Sun, Qian\|Luo, Jin\|Cheng, Bin
PMID:	22986536

26.
Journal:	Oncol Rep. 2013 Jan;29(1):362-70.
Title:	The Notch1/cyclooxygenase-2/Snail/E-cadherin pathway is associated with hypoxia-induced hepatocellular carcinoma cell invasion and migration.
Author:	Yu, Ling-Xiang\|Zhou, Liang\|Li, Mo\|Li, Zhi-Wei\|Wang, De-Sheng\|Zhang, Shao-Geng
PMID:	23124652

27.
Journal:	Tumour Biol. 2013 Feb;34(1):543-53.
Title:	Associations between high levels of Notch1 expression and high invasion and poor overall survival in hepatocellular carcinoma.
Author:	Zhou, Liang\|Zhang, Ning\|Li, Qing-Jun\|Sun, Wei\|Zhang, Yong\|Wang, De-Sheng\|Dou, Ke-Feng
PMID:	23179396

28.
Journal:	Int J Oncol. 2013 May;42(5):1636-43.
Title:	The hepatitis B virus X protein downregulates NF-kappaB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Author:	Luo, Jing\|Zhou, Haiyan\|Wang, Fan\|Xia, Xiumei\|Sun, Qian\|Wang, Ronghua\|Cheng, Bin
PMID:	23450368

29.
Journal:	PLoS One. 2013;8(2):e57382.
Title:	The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma.
Author:	Zhou, Liang\|Zhang, Ning\|Song, Wenjie\|You, Nan\|Li, Qingjun\|Sun, Wei\|Zhang, Yong\|Wang, Desheng\|Dou, Kefeng
PMID:	23468978

30.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2013 Apr;33(4):590-2, 597.
Title:	[Relationship between glypican-3 and Notch1 expressions in hepatocellular carcinoma].
Author:	Peng, Fanli\|Wu, Ziqing\|Li, Xuenong
PMID:	23644127

31.
Journal:	Hepatobiliary Pancreat Dis Int. 2013 Jun;12(3):286-94.
Title:	Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma.
Author:	Ahn, Soomin\|Hyeon, Jiyeon\|Park, Cheol-Keun
PMID:	23742774

32.
Journal:	Int J Surg Pathol. 2013 Oct;21(5):449-54.
Title:	Elevated expression of notch1 is associated with metastasis of human malignancies.
Author:	Zhu, He\|Zhou, Xinchun\|Redfield, Samantha\|He, Zhi\|Lewin, Jack\|Miele, Lucio
PMID:	23883974

33.
Journal:	PLoS One. 2013 Dec 27;8(12):e83699.
Title:	Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells.
Author:	Zhang, Song\|Yang, Yang\|Liang, Zhenxing\|Duan, Weixun\|Yang, Jian\|Yan, Juanjuan\|Wang, Ning\|Feng, Wenqiang\|Ding, Meiling\|Nie, Yongzhan\|Jin, Zhenxiao
PMID:	24386256

34.
Journal:	Oncol Rep. 2014 Feb;31(2):933-9.
Title:	Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Author:	Sun, Qian\|Wang, Ronghua\|Wang, Yan\|Luo, Jing\|Wang, Peng\|Cheng, Bin
PMID:	24336972

35.
Journal:	Free Radic Res. 2014 Jul;48(7):806-13.
Title:	Notch1 increases Snail expression under high reactive oxygen species conditions in hepatocellular carcinoma cells.
Author:	Kim, H S\|Jung, G
PMID:	24684482

36.
Journal:	Int J Oncol. 2014 Oct;45(4):1638-48.
Title:	Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/beta-catenin pathway.
Author:	Sun, Qian\|Wang, Ronghua\|Luo, Jing\|Wang, Peng\|Xiong, Si\|Liu, Man\|Cheng, Bin
PMID:	25017705

37.
Journal:	Int J Clin Exp Pathol. 2014 May 15;7(6):3272-9. eCollection 2014.
Title:	Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.
Author:	Wu, Wen-Rui\|Shi, Xiang-De\|Zhang, Rui\|Zhu, Man-Sheng\|Xu, Lei-Bo\|Yu, Xian-Huan\|Zeng, Hong\|Wang, Jie\|Liu, Chao
PMID:	25031748

38.
Journal:	Biomed Pharmacother. 2014 Jul;68(6):785-90.
Title:	Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling.
Author:	Annani-Akollor, Max Efui\|Wang, Shujing\|Fan, Jianhui\|Liu, Linhua\|Padhiar, Arshad Ahmed\|Zhang, Jianing
PMID:	25107841

39.
Journal:	Int J Mol Med. 2014 Oct;34(4):1081-6.
Title:	Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK.
Author:	Hu, Yan-Jian\|Li, Hong-Ying\|Qiu, Kai-Jie\|Li, Da-Chuan\|Zhou, Jia-Hui\|Hu, Yan-Hua\|Zhang, Feng-Min
PMID:	25110169

40.
Journal:	Int J Oncol. 2014 Nov;45(5):1883-90.
Title:	Spatial localization of the JAG1/Notch1/osteopontin cascade modulates extrahepatic metastasis in hepatocellular carcinoma.
Author:	Xue, Tong-Chun\|Zou, Jing-Huai\|Chen, Rong-Xin\|Cui, Jie-Feng\|Tang, Zhao-You\|Ye, Sheng-Long
PMID:	25176314

41.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2014 May;22(5):354-7.
Title:	[Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells].
Author:	Li, Jianfang\|Ding, Shixiong\|Ying, Liping\|Hu, Airong\|Hu, Yaoren\|Liang, Xiaoyue
PMID:	25180870

42.
Journal:	Biomed Pharmacother. 2014 Oct;68(8):943-9.
Title:	miR-429 represses cell proliferation and induces apoptosis in HBV-related HCC.
Author:	Gao, Huijie\|Liu, Chao
PMID:	25312821

43.
Journal:	Int J Clin Exp Pathol. 2014 Aug 15;7(9):5782-91. eCollection 2014.
Title:	Association of Notch1 with vasculogenic mimicry in human hepatocellular carcinoma cell lines.
Author:	Zhu, Man-Sheng\|Xu, Lei-Bo\|Zeng, Hong\|Shi, Xiang-De\|Wu, Wen-Rui\|Liu, Chao
PMID:	25337219

44.
Journal:	Mol Cytogenet. 2014 Nov 25;7(1):81.
Title:	Recurrent genetic alterations in hepatitis C-associated hepatocellular carcinoma detected by genomic microarray: a genetic, clinical and pathological correlation study.
Author:	Liu, Yajuan J\|Zhou, Yang\|Yeh, Matthew M
PMID:	25469175

45.
Journal:	Hepatology. 2015 Mar;61(3):942-52.
Title:	Differential effects of targeting Notch receptors in a mouse model of liver cancer.
Author:	Huntzicker, Erik G\|Hotzel, Kathy\|Choy, Lisa\|Che, Li\|Ross, Jed\|Pau, Gregoire\|Sharma, Neeraj\|Siebel, Christian W\|Chen, Xin\|French, Dorothy M
PMID:	25311838

46.
Journal:	Mol Med Rep. 2015 Jan;11(1):357-61.
Title:	Total alkaloids of Rubus alceifolius Poir inhibit tumor angiogenesis through suppression of the Notch signaling pathway in a mouse model of hepatocellular carcinoma.
Author:	Zhao, Jinyan\|Lin, Wei\|Cao, Zhiyun\|Zhuang, Qunchuan\|Zheng, Liangpu\|Peng, Jun\|Hong, Zhenfeng
PMID:	25333354

47.
Journal:	Mol Med Rep. 2015 Mar;11(3):2334-40.
Title:	Simvastatin induces growth inhibition and apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells via upregulation of Notch1 expression.
Author:	Huang, Xin\|Ma, Jiancang\|Xu, Jinkai\|Su, Qinghua\|Zhao, Jun
PMID:	25412322

48.
Journal:	Oncotarget. 2015 Mar 10;6(7):5102-17.
Title:	Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
Author:	Matsushita, Kazuyuki\|Kitamura, Kouichi\|Rahmutulla, Bahityar\|Tanaka, Nobuko\|Ishige, Takayuki\|Satoh, Mamoru\|Hoshino, Tyuji\|Miyagi, Satoru\|Mori, Takeshi\|Itoga, Sakae\|Shimada, Hideaki\|Tomonaga, Takeshi\|Kito, Minoru\|Nakajima-Takagi, Yaeko\|Kubo, Shuji\|Nakaseko,
PMID:	25671302

49.
Journal:	J Transl Med. 2015 Mar 26;13:100.
Title:	Ganoderma lucidum polysaccharide extract inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation and function by inducing microRNA-125b.
Author:	Li, Aimei\|Shuai, Xuanyu\|Jia, Zhijun\|Li, Hangyu\|Liang, Xiubin\|Su, Dongming\|Guo, Wanhua
PMID:	25889022

50.
Journal:	Int J Oncol. 2015 Jul;47(1):231-43.
Title:	Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway.
Author:	Wang, Xing\|Zhang, Juan\|Zhou, Liang\|Sun, Wei\|Zheng, Zhi-Gang\|Lu, Peng\|Gao, Yuan\|Yang, Xi-Sheng\|Zhang, Zhuo-Chao\|Tao, Kai-Shan\|Dou, Ke-Feng
PMID:	25955618

51.
Journal:	PLoS One. 2015 May 26;10(5):e0127464.
Title:	Xanthohumol inhibits Notch signaling and induces apoptosis in hepatocellular carcinoma.
Author:	Kunnimalaiyaan, Selvi\|Sokolowski, Kevin M\|Balamurugan, Mariappan\|Gamblin, T Clark\|Kunnimalaiyaan, Muthusamy
PMID:	26011160

52.
Journal:	Oncol Rep. 2015 Oct;34(4):1650-8.
Title:	NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells.
Author:	Hayashi, Yoshihiro\|Osanai, Makoto\|Lee, Gang-Hong
PMID:	26252838

53.
Journal:	Biomaterials. 2015 Nov;70:71-83.
Title:	Co-delivery of platinum drug and siNotch1 with micelleplex for enhanced hepatocellular carcinoma therapy.
Author:	Shen, Song\|Sun, Chun-Yang\|Du, Xiao-Jiao\|Li, Hong-Jun\|Liu, Yang\|Xia, Jin-Xing\|Zhu, Yan-Hua\|Wang, Jun
PMID:	26302232

54.
Journal:	J Cancer. 2015 Aug 22;6(10):996-1004.
Title:	The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.
Author:	Sun, Guangchun\|Mackey, Lily V\|Coy, David H\|Yu, Cui-Yun\|Sun, Lichun
PMID:	26366213

55.
Journal:	Oncol Rep. 2015 Dec;34(6):3174-86.
Title:	Loss of function of Notch1 identifies a poor prognosis group of early stage hepatocellular carcinoma following hepatectomy.
Author:	Liu, Jian\|Liu, Jing-Feng\|Wang, Kui\|Yan, Zhen-Lin\|Wan, Xu-Ying\|Huang, Ai-Min\|Wang, Yi-Zhou\|Li, Jun\|Xia, Yong\|Shi, Le-Hua\|Jiao, Bing-Hua\|Zhang, Yongjie\|Shen, Feng
PMID:	26398566

56.
Journal:	Life Sci. 2015 Dec 15;143:18-26.
Title:	Interferon-alpha2b gene-modified human bone marrow mesenchymal stem cells inhibit hepatocellular carcinoma by reducing the Notch1 levels.
Author:	Su, Yanjun\|Cheng, Ruochuan\|Zhang, Jianming\|Qian, Jun\|Diao, Chang\|Ran, Jianghua\|Zhang, Hongqing\|Li, Li
PMID:	26518164

57.
Journal:	Int J Clin Exp Med. 2015 Sep 15;8(9):16880-9. eCollection 2015.
Title:	KRT6B, a key mediator of notch signaling in honokiol-induced human hepatoma cell apoptosis.
Author:	Zhang, Haoxuan\|Huo, Mingsheng\|Jia, Yin\|Xu, Ao
PMID:	26629239

58.
Journal:	Gut. 2016 Oct;65(10):1765-75.
Title:	LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Author:	Scarzello, Anthony J\|Jiang, Qun\|Back, Timothy\|Dang, Hien\|Hodge, Deborah\|Hanson, Charlotte\|Subleski, Jeffrey\|Weiss, Jonathan M\|Stauffer, Jimmy K\|Chaisaingmongkol, Jitti\|Rabibhadana, Siritida\|Ruchirawat, Mathuros\|Ortaldo, John\|Wang, Xin Wei\|Norris, Paula S\|
PMID:	26206664

59.
Journal:	Tumour Biol. 2016 Mar;37(3):3675-81.
Title:	TGF-beta1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells.
Author:	Wang, Xin-Hong\|Liu, Ming-Na\|Sun, Xun\|Xu, Chun-Huan\|Liu, Jing\|Chen, Jing\|Xu, Rui-Ling\|Li, Bao-Xin
PMID:	26462837

60.
Journal:	Mol Cell Biochem. 2016 Jan;411(1-2):307-15.
Title:	Inhibition of perillyl alcohol on cell invasion and migration depends on the Notch signaling pathway in hepatoma cells.
Author:	Ma, Yong\|Bian, Jianmin\|Zhang, Feng
PMID:	26475687

61.
Journal:	Int J Oncol. 2016 Jan;48(1):329-37.
Title:	Hepatitis B virus X protein activates Notch signaling by its effects on Notch1 and Notch4 in human hepatocellular carcinoma.
Author:	Gao, Juan\|Xiong, Yimin\|Wang, Yan\|Wang, Yiming\|Zheng, Guorong\|Xu, Hualin
PMID:	26530164

62.
Journal:	Tumour Biol. 2016 May;37(5):6073-84.
Title:	CD24 promotes HCC progression via triggering Notch-related EMT and modulation of tumor microenvironment.
Author:	Wan, Xin\|Cheng, Ci\|Shao, Qing\|Lin, Zhe\|Lu, Shuai\|Chen, Yun
PMID:	26608371

63.
Journal:	Hepatology. 2016 Apr;63(4):1256-71.
Title:	Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition.
Author:	Xiao, Shuai\|Chang, Rui-Min\|Yang, Ming-Yang\|Lei, Xiong\|Liu, Xiao\|Gao, Wen-Bin\|Xiao, Jing-Lei\|Yang, Lian-Yue
PMID:	26698646

64.
Journal:	Oncotarget. 2016 Feb 2;7(5):5754-68.
Title:	Notch and Wnt/beta-catenin signaling pathway play important roles in activating liver cancer stem cells.
Author:	Wang, Ronghua\|Sun, Qian\|Wang, Peng\|Liu, Man\|Xiong, Si\|Luo, Jing\|Huang, Hai\|Du, Qiang\|Geller, David A\|Cheng, Bin
PMID:	26735577

65.
Journal:	PLoS One. 2016 Jan 14;11(1):e0146696.
Title:	Hepatitis B Virus HBx Activates Notch Signaling via Delta-Like 4/Notch1 in Hepatocellular Carcinoma.
Author:	Kongkavitoon, Pornrat\|Tangkijvanich, Pisit\|Hirankarn, Nattiya\|Palaga, Tanapat
PMID:	26766040

66.
Journal:	Am J Surg. 2016 Apr;211(4):755-60.
Title:	Role of Akt inhibition on Notch1 expression in hepatocellular carcinoma: potential role for dual targeted therapy.
Author:	Sokolowski, Kevin M\|Balamurugan, Mariappan\|Kunnimalaiyaan, Selvi\|Wilson, Jacob\|Gamblin, Thomas Clark\|Kunnimalaiyaan, Muthusamy
PMID:	26850133

67.
Journal:	World J Gastroenterol. 2016 Feb 14;22(6):2071-80.
Title:	Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice.
Author:	Ding, Ning\|Che, Li\|Li, Xiao-Lei\|Liu, Yan\|Jiang, Li-Jie\|Fan, Biao\|Tao, Jun-Yan\|Chen, Xin\|Ji, Jia-Fu
PMID:	26877611

68.
Journal:	Int J Oncol. 2016 May;48(5):1868-76.
Title:	Corilagin suppresses cholangiocarcinoma progression through Notch signaling pathway in vitro and in vivo.
Author:	Gu, Yue\|Xiao, Linfeng\|Ming, Yanlin\|Zheng, Zhizhong\|Li, Wengang
PMID:	26935808

69.
Journal:	Biol Cell. 2016 Apr;108(4):113.
Title:	Corrigendum.
Author:
PMID:	27038038

70.
Journal:	Oncotarget. 2016 Jun 28;7(26):39609-39626.
Title:	Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma.
Author:	Giovannini, Catia\|Minguzzi, Manuela\|Genovese, Filippo\|Baglioni, Michele\|Gualandi, Alessandra\|Ravaioli, Matteo\|Milazzo, Maddalena\|Tavolari, Simona\|Bolondi, Luigi\|Gramantieri, Laura
PMID:	27167202

71.
Journal:	Sci Rep. 2016 May 17;6:25975.
Title:	A systems biology pipeline identifies new immune and disease related molecular signatures and networks in human cells during microgravity exposure.
Author:	Mukhopadhyay, Sayak\|Saha, Rohini\|Palanisamy, Anbarasi\|Ghosh, Madhurima\|Biswas, Anupriya\|Roy, Saheli\|Pal, Arijit\|Sarkar, Kathakali\|Bagh, Sangram
PMID:	27185415

72.
Journal:	Int J Mol Med. 2016 Aug;38(2):551-7.
Title:	Astragalus polysaccharide induces the apoptosis of human hepatocellular carcinoma cells by decreasing the expression of Notch1.
Author:	Huang, Wen-Hai\|Liao, Wei-Rong\|Sun, Rong-Xun
PMID:	27279598

73.
Journal:	Cancer Res. 2016 Dec 1;76(23):7059-7071.
Title:	NRBP2 Overexpression Increases the Chemosensitivity of Hepatocellular Carcinoma Cells via Akt Signaling.
Author:	Zhang, Lixing\|Ge, Chao\|Zhao, Fangyu\|Zhang, Yang\|Wang, Xin\|Yao, Ming\|Li, Jinjun
PMID:	27634758

74.
Journal:	Oncotarget. 2016 Nov 22;7(47):77987-77997.
Title:	Vasculogenic mimicry in hepatocellular carcinoma contributes to portal vein invasion.
Author:	Jue, Chen\|Zhifeng, Wu\|Zhisheng, Zhang\|Lin, Cui\|Yayun, Qian\|Feng, Jin\|Hao, Gu\|Shintaro, Ishikawa\|Hisamitsu, Tadashi\|Shiyu, Guo\|Yanqing, Liu
PMID:	27793002

75.
Journal:	J Exp Clin Cancer Res. 2016 Nov 7;35(1):172.
Title:	Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-kappaB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells.
Author:	Kong, Fanyun\|Hu, Wei\|Zhou, Kai\|Wei, Xiao\|Kou, Yanbo\|You, Hongjuan\|Zheng, Kuiyang\|Tang, Renxian
PMID:	27821177

76.
Journal:	Eur Rev Med Pharmacol Sci. 2016 Oct;20(20):4266-4273.
Title:	A personalized approach identifies disturbed pathways and key genes in hepatitis C virus-cirrhosis with hepatocellular carcinoma.
Author:	Li, Y-L\|Zheng, M-X\|Wang, G
PMID:	27831648

77.
Journal:	Oncotarget. 2017 Jan 10;8(2):2501-2513.
Title:	Notch1 promotes vasculogenic mimicry in hepatocellular carcinoma by inducing EMT signaling.
Author:	Jue, Chen\|Lin, Cui\|Zhisheng, Zhang\|Yayun, Qian\|Feng, Jin\|Min, Zhao\|Haibo, Wang\|Youyang, Shi\|Hisamitsu, Tadashi\|Shintaro, Ishikawa\|Shiyu, Guo\|Yanqing, Liu
PMID:	27705934

78.
Journal:	Oncol Rep. 2017 Jan;37(1):348-356.
Title:	Hepatitis B virus X protein and hypoxiainducible factor-1alpha stimulate Notch gene expression in liver cancer cells.
Author:	Yang, Sheng-Li\|Ren, Quan-Guang\|Zhang, Tao\|Pan, Xiaoli\|Wen, Lu\|Hu, Jian-Li\|Yu, Chao\|He, Qian-Jin
PMID:	27840976

79.
Journal:	Peptides. 2017 Feb;88:62-66.
Title:	Increased FNDC5/Irisin expression in human hepatocellular carcinoma.
Author:	Gaggini, Melania\|Cabiati, Manuela\|Del Turco, Serena\|Navarra, Teresa\|De Simone, Paolo\|Filipponi, Franco\|Del Ry, Silvia\|Gastaldelli, Amalia\|Basta, Giuseppina
PMID:	28012856

80.
Journal:	Oncotarget. 2017 Feb 21;8(8):13264-13276.
Title:	MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway.
Author:	Wang, Xiao-Ping\|Zhou, Jian\|Han, Ming\|Chen, Chuan-Bao\|Zheng, Yi-Tao\|He, Xiao-Shun\|Yuan, Xiao-Peng
PMID:	28129650

81.
Journal:	Exp Cell Res. 2017 Mar 15;352(2):375-381.
Title:	NOR1 promotes hepatocellular carcinoma cell proliferation and migration through modulating the Notch signaling pathway.
Author:	You, Kun\|Sun, Peisheng\|Yue, Zhongyi\|Li, Jian\|Xiong, Wancheng\|Wang, Jianguo
PMID:	28232113

82.
Journal:	Oncotarget. 2017 Apr 4;8(14):23289-23302.
Title:	Activated Notch signaling augments cell growth in hepatocellular carcinoma via up-regulating the nuclear receptor NR4A2.
Author:	Zhu, Bo\|Sun, Lichun\|Luo, Wei\|Li, Min\|Coy, David H\|Yu, Long\|Yu, Wenbo
PMID:	28423575

83.
Journal:	Oncotarget. 2017 Jul 11;8(28):45837-45847.
Title:	Notch1 regulates the JNK signaling pathway and increases apoptosis in hepatocellular carcinoma.
Author:	Sui, Chengxu\|Zhuang, Chengjun\|Sun, Deguang\|Yang, Li\|Zhang, Liang\|Song, Lei
PMID:	28507277

84.
Journal:	Mol Cancer Ther. 2017 Aug;16(8):1531-1543.
Title:	Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3.
Author:	Wu, Chuan Xing\|Xu, Aimin\|Zhang, Cathy C\|Olson, Peter\|Chen, Lin\|Lee, Terence K\|Cheung, Tan To\|Lo, Chung Mau\|Wang, Xiao Qi
PMID:	28522590

85.
Journal:	Cell Death Differ. 2017 Sep;24(9):1577-1587.
Title:	Hepatitis B virus X protein promotes CREB-mediated activation of miR-3188 and Notch signaling in hepatocellular carcinoma.
Author:	Zhou, Shao-Jun\|Deng, Yue-Ling\|Liang, Hui-Fang\|Jaoude, Jonathan C\|Liu, Fu-Yao
PMID:	28574502

86.
Journal:	J Ethnopharmacol. 2017 Aug 17;208:165-173.
Title:	COE inhibits vasculogenic mimicry in hepatocellular carcinoma via suppressing Notch1 signaling.
Author:	Jue, Chen\|Min, Zhao\|Zhisheng, Zhang\|Lin, Cui\|Yayun, Qian\|Xuanyi, Wang\|Feng, Jin\|Haibo, Wang\|Youyang, Shi\|Tadashi, Hisamitsu\|Shintaro, Ishikawa\|Shiyu, Guo\|Yanqing, Liu
PMID:	28694103

87.
Journal:	J Virol. 2017 Oct 13;91(21). pii: JVI.01235-17.
Title:	Hepatitis C Virus Core Protein Modulates Endoglin (CD105) Signaling Pathway for Liver Pathogenesis.
Author:	Kwon, Young-Chan\|Sasaki, Reina\|Meyer, Keith\|Ray, Ranjit
PMID:	28794048

88.
Journal:	Oncol Lett. 2017 Sep;14(3):3616-3622.
Title:	The role of Jagged1/Notch pathway-mediated angiogenesis of hepatocarcinoma cells in vitro, and the effects of the spleen-invigorating and blood stasis-removing recipe.
Author:	Lin, Juze\|Lin, Yongxin\|Su, Le\|Su, Qiao\|Guo, Wei\|Huang, Xuhui\|Wang, Changjun\|Lin, Lizhu
PMID:	28927121

89.
Journal:	Clin Cancer Res. 2017 Dec 1;23(23):7209-7216.
Title:	Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer.
Author:	Joung, Je-Gun\|Oh, Bo Young\|Hong, Hye Kyung\|Al-Khalidi, Hisham\|Al-Alem, Faisal\|Lee, Hae-Ock\|Bae, Joon Seol\|Kim, Jinho\|Cha, Hong-Ui\|Alotaibi, Maram\|Cho, Yong Beom\|Hassanain, Mazen\|Park, Woong-Yang\|Lee, Woo Yong
PMID:	28939741

90.
Journal:	World J Gastroenterol. 2017 Sep 14;23(34):6242-6251.
Title:	Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells.
Author:	Lu, Cai-Jie\|He, Yi-Feng\|Yuan, Wei-Zhuang\|Xiang, Li-Jun\|Zhang, Jian\|Liang, Yan-Rui\|Duan, Juan\|He, Yun-He\|Li, Ming-Yi
PMID:	28974890

91.
Journal:	Int J Oncol. 2017 Nov;51(5):1449-1459.
Title:	Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
Author:	Liao, Bo\|Zhou, Honghao\|Liang, Huifang\|Li, Changhai
PMID:	29048612

92.
Journal:	Oncol Lett. 2017 Dec;14(6):7889-7895.
Title:	Lidamycin decreases CD133 expression in hepatocellular carcinoma via the Notch signaling pathway.
Author:	Chen, Yi\|Sun, Wenwei\|He, Ran\|Zhang, Feiyan\|Wang, Hongyu\|Li, Panhong\|Shao, Rong-Guang\|Xu, Xiaoyu
PMID:	29344233

93.
Journal:	Curr Drug Targets. 2018;19(2):128-143.
Title:	Notch Signalling Pathways and Their Importance in the Treatment of Cancers.
Author:	Teoh, Seong Lin\|Das, Srijit
PMID:	28294046

94.
Journal:	Immunobiology. 2018 Jan;223(1):73-80.
Title:	Hepatic leukemia-associated macrophages exhibit a pro-inflammatory phenotype in Notch1-induced acute T cell leukemia.
Author:	Yang, Xiao\|Feng, Wenli\|Wang, Rong\|Yang, Feifei\|Wang, Lina\|Chen, Shayan\|Chen, Chong\|Ren, Qian\|Zheng, Guoguang
PMID:	29030004

95.
Journal:	Acta Histochem. 2018 Feb;120(2):95-102.
Title:	MiR-199-3p replacement affects E-cadherin expression through Notch1 targeting in hepatocellular carcinoma.
Author:	Giovannini, Catia\|Fornari, Francesca\|Dallo, Rossella\|Gagliardi, Martina\|Nipoti, Elisa\|Vasuri, Francesco\|Coada, Camelia Alexandra\|Ravaioli, Matteo\|Bolondi, Luigi\|Gramantieri, Laura
PMID:	29249451

96.
Journal:	Cancer Biomark. 2018 Feb 14;21(3):575-582.
Title:	LINC00261 suppresses cell proliferation, invasion and Notch signaling pathway in hepatocellular carcinoma.
Author:	Zhang, Hai-Feng\|Li, Wei\|Han, Yi-Di
PMID:	29278875

97.
Journal:	Oncol Res. 2018 Feb 22.
Title:	Long non-coding RNA CCAL promotes papillary thyroid cancer progression by activation of NOTCH1 pathway.
Author:	Ye, Ying\|Song, Yanan\|Zhuang, Juhua\|He, Saifei\|Ni, Jing\|Xia, Wei
PMID:	29471887

98.
Journal:	Am J Cancer Res. 2018 Feb 1;8(2):302-316. eCollection 2018.
Title:	Cancer-associated fibroblasts promote stem cell-like properties of hepatocellular carcinoma cells through IL-6/STAT3/Notch signaling.
Author:	Xiong, Si\|Wang, Ronghua\|Chen, Qian\|Luo, Jing\|Wang, Jinlin\|Zhao, Zhenxiong\|Li, Yawen\|Wang, Yun\|Wang, Xiju\|Cheng, Bin
PMID:	29511600

99.
Journal:	Oncogene. 2018 Jun;37(24):3229-3242.
Title:	Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
Author:	Wang, Jingxiao\|Dong, Mingjie\|Xu, Zhong\|Song, Xinhua\|Zhang, Shanshan\|Qiao, Yu\|Che, Li\|Gordan, John\|Hu, Kaiwen\|Liu, Yan\|Calvisi, Diego F\|Chen, Xin
PMID:	29545603

100.
Journal:	Mol Cancer. 2018 Jun 12;17(1):94.
Title:	Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a.
Author:	Xin, Xiaoru\|Wu, Mengying\|Meng, Qiuyu\|Wang, Chen\|Lu, Yanan\|Yang, Yuxin\|Li, Xiaonan\|Zheng, Qidi\|Pu, Hu\|Gui, Xin\|Li, Tianming\|Li, Jiao\|Jia, Song\|Lu, Dongdong
PMID:	29895332

101.
Journal:	Exp Cell Res. 2018 Sep 15;370(2):373-382.
Title:	ADAM17 promotes cell migration and invasion through the integrin beta1 pathway in hepatocellular carcinoma.
Author:	Li, Yong\|Ren, Zhen\|Wang, Yu\|Dang, Ya-Zheng\|Meng, Bo-Xiang\|Wang, Guo-Dong\|Zhang, Jing\|Wu, Jiao\|Wen, Ning
PMID:	29966664

102.
Journal:	J Biochem Mol Toxicol. 2018 Aug;32(8):e22167.
Title:	MicroRNA-760 Inhibits Doxorubicin Resistance in Hepatocellular Carcinoma through Regulating Notch1/Hes1-PTEN/Akt Signaling Pathway.
Author:	Tian, Tao\|Fu, Xiao\|Lu, Jun\|Ruan, Zhiping\|Nan, Kejun\|Yao, Yu\|Yang, Yujuan
PMID:	29968951

103.
Journal:	Int J Cancer. 2018 Jul 7.
Title:	Modification of alpha2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Author:	Yuan, Qingmin\|Chen, Xixi\|Han, Yang\|Lei, Ting\|Wu, Qiang\|Yu, Xiao\|Wang, Liping\|Fan, Zhe\|Wang, Shujing
PMID:	29981167

104.
Journal:	Oncol Rep. 2018 Sep;40(3):1515-1524.
Title:	Combined antitumor effects of 1,25dihydroxy vitamin D3 and Notch inhibitor in liver cancer.
Author:	Cai, Lijing\|Luo, Lifang\|Tang, Zhimou\|Meng, Xiaohui
PMID:	30015939

105.
Journal:	J Cancer. 2018 Jun 23;9(15):2678-2686.
Title:	Mutations in NOTCH1 and nucleotide excision repair genes are correlated with prognosis of hepatitis B virus-associated hepatocellular carcinoma.
Author:	Su, Wen-Hui\|Jou, Yuh-Shan\|Zhang, Jia-Hao\|Ho, Chun-Ming\|Tai, Dar-In
PMID:	30087708

106.
Journal:	Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10127-E10136.
Title:	iNOS promotes CD24(+)CD133(+) liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway.
Author:	Wang, Ronghua\|Li, Yawen\|Tsung, Allan\|Huang, Hai\|Du, Qiang\|Yang, Muqing\|Deng, Meihong\|Xiong, Si\|Wang, Xiju\|Zhang, Liyong\|Geller, David A\|Cheng, Bin\|Billiar, Timothy R
PMID:	30297396

107.
Journal:	Biochem Biophys Res Commun. 2018 Oct 29. pii: S0006-291X(18)32310-6.
Title:	Regulation of periostin expression by Notch signaling in hepatocytes and liver cancer cell lines.
Author:	Kongkavitoon, Pornrat\|Butta, Patcharavadee\|Sanpavat, Anapat\|Bhattarakosol, Pattarasinee\|Tangtanatakul, Pattarin\|Wongprom, Benjawan\|Tangkijvanich, Pisit\|Hirankarn, Nattiya\|Palaga, Tanapat
PMID:	30384995