Primary Site >> Colorectal Cancer

Gene >> NOS3

Journal: Carcinogenesis. 1996 May;17(5):1171-4.
Title: Nitric oxide synthase activity and expression in human colorectal cancer.
Author: Moochhala, S|Chhatwal, V J|Chan, S T|Ngoi, S S|Chia, Y W|Rauff, A
PMID: 8640931
Journal: Cancer Res. 1997 Apr 1;57(7):1233-7.
Title: Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane.
Author: Takahashi, M|Fukuda, K|Ohata, T|Sugimura, T|Wakabayashi, K
PMID: 9102204
Journal: Biol Res. 2002;35(2):169-76.
Title: Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells.
Author: Felley-Bosco, Emanuela|Bender, Florent|Quest, Andrew F G
PMID: 12415733
Journal: Cancer Lett. 2004 Dec 8;216(1):109-14.
Title: High expression of endothelial cell nitric oxide synthase in peritumoral microvessels predicts increased disease-free survival in colorectal cancer.
Author: Mortensen, Kirsten|Christensen, Ib Jarle|Nielsen, Hans Jorgen|Hansen, Ulla|Larsson, Lars-Inge
PMID: 15500954
Journal: Mol Carcinog. 2006 Feb;45(2):93-105.
Title: The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.
Author: Yerushalmi, Hagit F|Besselsen, David G|Ignatenko, Natalia A|Blohm-Mangone, Karen A|Padilla-Torres, Jose L|Stringer, David E|Cui, Haiyan|Holubec, Hana|Payne, Claire M|Gerner, Eugene W
PMID: 16329147
Journal: Oncol Rep. 2006 Aug;16(2):353-9.
Title: Genetic analysis of caveolin-1 and eNOS genes in colorectal cancer.
Author: Conde, Manuel Chaves|Ramirez-Lorca, Reposo|Lopez-Jamar, Jose Miguel Esteban|Molero, Eva|Ramirez-Armengol, Juan Andres|Moreno Nogueira, Jose Andres|Pascual, Manuel Hidalgo|Ruiz, Agustin|Martin-Cordova, Carlos Garcia|Real, Luis Miguel|Royo, Jose Luis
PMID: 16820915
Journal: Stem Cells. 2006 Dec;24(12):2733-43.
Title: Endothelial differentiation potential of human monocyte-derived multipotential cells.
Author: Kuwana, Masataka|Okazaki, Yuka|Kodama, Hiroaki|Satoh, Takashi|Kawakami, Yutaka|Ikeda, Yasuo
PMID: 16888284
Journal: Mol Carcinog. 2007 May;46(5):341-53.
Title: Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis.
Author: Seril, Darren N|Liao, Jie|Yang, Guang-Yu
PMID: 17219424
Journal: Cancer Res. 2008 Mar 15;68(6):2043-50.
Title: Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Author: Singh, Rana P|Gu, Mallikarjuna|Agarwal, Rajesh
PMID: 18339887
Journal: Int J Cancer. 2009 Apr 1;124(7):1565-71.
Title: An intron 4 VNTR polymorphism of the endothelial nitric oxide synthase gene is associated with early-onset colorectal cancer.
Author: Yeh, Chih-Ching|Santella, Regina M|Hsieh, Ling-Ling|Sung, Fung-Chang|Tang, Reiping
PMID: 19115208
Journal: In Vitro Cell Dev Biol Anim. 2009 Oct;45(9):543-50.
Title: Transforming growth factor-beta1 (TGF-beta1) and acetylcholine (ACh) alter nitric oxide (NO) and interleukin-1beta (IL-1beta) secretion in human colon adenocarcinoma cells.
Author: Paduch, Roman|Kandefer-Szerszen, Martyna
PMID: 19551451
Journal: J Cancer Epidemiol. 2009;2009:302047.
Title: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy.
Author: Funke, Silvia|Risch, Angela|Nieters, Alexandra|Hoffmeister, Michael|Stegmaier, Christa|Seiler, Christoph M|Brenner, Hermann|Chang-Claude, Jenny
PMID: 20445800
Journal: Med Oncol. 2011 Dec;28(4):1075-9.
Title: No association of the eNOS gene polymorphisms with survival in patients with colorectal cancer.
Author: Kim, Yun Jeong|Lee, Soo Jung|Kim, Jong Gwang|Sohn, Sang Kyun|Chae, Yee Soo|Moon, Joon Ho|Kang, Byung Woog|Park, Jin Young|Park, Jun Seok|Choi, Gyu Seog
PMID: 20706876
Journal: Mol Biol Rep. 2012 Mar;39(3):3245-9.
Title: The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression in Turkish population.
Author: Arikan, Soykan|Cacina, Canan|Guler, Erkan|Culcu, Serdar|Tuna, Gulay|Yaylim-Eraltan, Ilhan
PMID: 21706163
Journal: Oncol Rep. 2013 Oct;30(4):1701-6.
Title: Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathways.
Author: Shen, Aling|Lin, Jiumao|Chen, Youqin|Lin, Wei|Liu, Liya|Hong, Zhenfeng|Sferra, Thomas J|Peng, Jun
PMID: 23843018
Journal: Chin J Cancer Res. 2013 Oct;25(5):572-84.
Title: Effects of tyrosine kinase inhibitor E7080 and eNOS inhibitor L-NIO on colorectal cancer alone and in combination.
Author: Altun, Ahmet|Temiz, Tijen Kaya|Balci, Ezgi|Polat, Zubeyde Akin|Turan, Mustafa
PMID: 24255582
Journal: Gene. 2013 Jan 10;512(2):275-81.
Title: Association of eNOS polymorphisms (-786T>C, 4a4b, 894G>T) with colorectal cancer susceptibility in the Korean population.
Author: Jang, Moon Ju|Jeon, Young Joo|Kim, Jong Woo|Chong, So Young|Hong, Sung Pyo|Oh, Doyeun|Cho, Yun Kyung|Chung, Ki Wha|Kim, Nam Keun
PMID: 23137631
Journal: Oncol Rep. 2013 Aug;30(2):952-60.
Title: Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats.
Author: Janakiram, Naveena B|Mohammed, Altaf|Ravillah, Durgadevi|Choi, Chang In|Zhang, Yuting|Desai, Dhimant|Amin, Shantu|Rao, Chinthalapally V
PMID: 23708609
Journal: Asian Pac J Cancer Prev. 2014;15(8):3811-5.
Title: Nitric oxide synthase 3 gene variants and colorectal cancer: a meta-analysis.
Author: Chen, Yang|Li, Jie|Guo, Yun|Guo, Xiao-Yun
PMID: 24870799
Journal: Int J Mol Sci. 2014 Jul 30;15(8):13333-43.
Title: Discrepancies between VEGF -1154 G>A polymorphism analysis performed in peripheral blood samples and FFPE tissue.
Author: Marisi, Giorgia|Passardi, Alessandro|Calistri, Daniele|Zoli, Wainer|Amadori, Dino|Ulivi, Paola
PMID: 25079441
Journal: Acta Pol Pharm. 2015 Jul-Aug;72(4):705-11.
Title: DOWN-REGULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION BY INOSITOL HEXAPHOSPHATE IN HUMAN COLON CANCER CELLS.
Author: Kapral, Malgorzata|Wawszczyk, Joanna|Sosnicki, Stanislaw|Weglarz, Ludmila
PMID: 26647627
Journal: J Transl Med. 2015 Aug 11;13:258.
Title: eNOS polymorphisms as predictors of efficacy of bevacizumab-based chemotherapy in metastatic colorectal cancer: data from a randomized clinical trial.
Author: Ulivi, Paola|Scarpi, Emanuela|Passardi, Alessandro|Marisi, Giorgia|Calistri, Daniele|Zoli, Wainer|Del Re, Marzia|Frassineti, Giovanni Luca|Tassinari, Davide|Tamberi, Stefano|Vertogen, Bernadette|Amadori, Dino
PMID: 26259598
Journal: Oncol Rep. 2015 Sep;34(3):1178-84.
Title: Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
Author: Jin, Soojung|Yun, Hee Jung|Jeong, Hyun Young|Oh, You Na|Park, Hyun-Jin|Yun, Seung-Geun|Kim, Byung Woo|Kwon, Hyun Ju
PMID: 26133679
Journal: Arch Pharm Res. 2015 Nov;38(11):1983-91.
Title: Immune modulation of glycosaminoglycan derived from P. lewisi in TNF-alpha stimulated cells.
Author: Ahn, Mi-Young|Kim, Soon-Ja|Kim, NamJung|Hwang, Jae Sam|Yun, Eun Young
PMID: 25981821
Journal: Biochim Biophys Acta. 2015 Feb;1852(2):277-89.
Title: Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy.
Author: Bouhidel, Jalaleddinne Omar|Wang, Ping|Siu, Kin Lung|Li, Hong|Youn, Ji Youn|Cai, Hua
PMID: 24928309
Journal: Cancer Res Treat. 2016 Jul;48(3):990-7.
Title: Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX.
Author: Kim, Mi-Jung|Han, Sae-Won|Lee, Dae-Won|Cha, Yongjun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Kim, Se Hyung|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 26790967
Journal: Vascul Pharmacol. 2017 Mar;90:27-35.
Title: Camptothecin promotes the production of nitric oxide that triggers subsequent S-nitrosoproteome-mediated signaling cascades in endothelial cells.
Author: Huang, Bin|Cheng, Jen-Kun|Wu, Chien-Yi|Chen, Ping-Ho|Tu, Po-Shu|Fu, Yaw-Syan|Wu, Chien-Hsing
PMID: 26239883
Journal: Oncotarget. 2017 Mar 7;8(10):16887-16898.
Title: IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients.
Author: Di Salvatore, Mariantonietta|Pietrantonio, Filippo|Orlandi, Armando|Del Re, Marzia|Berenato, Rosa|Rossi, Ernesto|Caporale, Marta|Guarino, Donatella|Martinetti, Antonia|Basso, Michele|Mennitto, Roberta|Santonocito, Concetta|Mennitto, Alessia|Schinzari, Gio
PMID: 28129643
Journal: Crit Rev Oncol Hematol. 2017 May;113:71-78.
Title: Kallistatin suppresses cancer development by multi-factorial actions.
Author: Chao, Julie|Li, Pengfei|Chao, Lee
PMID: 28427524
Journal: Int J Mol Sci. 2017 Jun 9;18(6). pii: ijms18061240.
Title: Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.
Author: Ulivi, Paola|Scarpi, Emanuela|Chiadini, Elisa|Marisi, Giorgia|Valgiusti, Martina|Capelli, Laura|Casadei Gardini, Andrea|Monti, Manlio|Ruscelli, Silvia|Frassineti, Giovanni Luca|Calistri, Daniele|Amadori, Dino|Passardi, Alessandro
PMID: 28598398
Journal: Mech Ageing Dev. 2018 Mar;170:22-29.
Title: Oxidative stress and inhibition of nitric oxide generation underlie methotrexate-induced senescence in human colon cancer cells.
Author: Dabrowska, Magdalena|Uram, Lukasz|Zielinski, Zbigniew|Rode, Wojciech|Sikora, Ewa
PMID: 28739375
Journal: BMC Biol. 2018 Jan 10;16(1):3.
Title: A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer.
Author: Penarando, Jon|Lopez-Sanchez, Laura M|Mena, Rafael|Guil-Luna, Silvia|Conde, Francisco|Hernandez, Vanessa|Toledano, Marta|Gudino, Victoria|Raponi, Michela|Billard, Caroline|Villar, Carlos|Diaz, Cesar|Gomez-Barbadillo, Jose|De la Haba-Rodriguez, Juan|Myant,
PMID: 29329541
Journal: Biochem Pharmacol. 2018 Apr;150:181-190.
Title: Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction.
Author: Sonowal, Himangshu|Pal, Pabitra|Shukla, Kirtikar|Saxena, Ashish|Srivastava, Satish K|Ramana, Kota V
PMID: 29458045