Primary Site >> Colorectal Cancer

Gene >> NOS3

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Ref: Nitric oxide synthase activity and expression in human colorectal cancer.
PMID: 8640931
Ref: Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane.
PMID: 9102204
Ref: Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells.
PMID: 12415733
Ref: High expression of endothelial cell nitric oxide synthase in peritumoral microvessels predicts increased disease-free survival in colorectal cancer.
PMID: 15500954
Ref: The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.
PMID: 16329147
Ref: Genetic analysis of caveolin-1 and eNOS genes in colorectal cancer.
PMID: 16820915
Ref: Endothelial differentiation potential of human monocyte-derived multipotential cells.
PMID: 16888284
Ref: Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis.
PMID: 17219424
Ref: Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
PMID: 18339887
Ref: An intron 4 VNTR polymorphism of the endothelial nitric oxide synthase gene is associated with early-onset colorectal cancer.
PMID: 19115208
Ref: Transforming growth factor-beta1 (TGF-beta1) and acetylcholine (ACh) alter nitric oxide (NO) and interleukin-1beta (IL-1beta) secretion in human colon adenocarcinoma cells.
PMID: 19551451
Ref: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy.
PMID: 20445800
Ref: No association of the eNOS gene polymorphisms with survival in patients with colorectal cancer.
PMID: 20706876
Ref: The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression in Turkish population.
PMID: 21706163
Ref: Association of eNOS polymorphisms (-786T>C, 4a4b, 894G>T) with colorectal cancer susceptibility in the Korean population.
PMID: 23137631
Ref: Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats.
PMID: 23708609
Ref: Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathways.
PMID: 23843018
Ref: Effects of tyrosine kinase inhibitor E7080 and eNOS inhibitor L-NIO on colorectal cancer alone and in combination.
PMID: 24255582
Ref: Nitric oxide synthase 3 gene variants and colorectal cancer: a meta-analysis.
PMID: 24870799
Ref: Discrepancies between VEGF -1154 G>A polymorphism analysis performed in peripheral blood samples and FFPE tissue.
PMID: 25079441
Ref: Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy.
PMID: 24928309
Ref: Immune modulation of glycosaminoglycan derived from P. lewisi in TNF-alpha stimulated cells.
PMID: 25981821
Ref: Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
PMID: 26133679
Ref: eNOS polymorphisms as predictors of efficacy of bevacizumab-based chemotherapy in metastatic colorectal cancer: data from a randomized clinical trial.
PMID: 26259598
Ref: DOWN-REGULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION BY INOSITOL HEXAPHOSPHATE IN HUMAN COLON CANCER CELLS.
PMID: 26647627
Ref: Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX.
PMID: 26790967
Ref: Camptothecin promotes the production of nitric oxide that triggers subsequent S-nitrosoproteome-mediated signaling cascades in endothelial cells.
PMID: 26239883
Ref: IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients.
PMID: 28129643
Ref: Kallistatin suppresses cancer development by multi-factorial actions.
PMID: 28427524
Ref: Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.
PMID: 28598398
Ref: Oxidative stress and inhibition of nitric oxide generation underlie methotrexate-induced senescence in human colon cancer cells.
PMID: 28739375
Ref: A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer.
PMID: 29329541
Ref: Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction.
PMID: 29458045