Primary Site >> Colorectal Cancer

Gene >> NLRP3

Journal: Acta Biochim Pol. 2009;56(3):465-9. Epub 2009 Jul 27.
Title: Arginase isoenzymes in human cirrhotic liver.
Author: Chrzanowska, Alicja|Gajewska, Beata|Baranczyk-Kuzma, Anna
PMID: 19636440
Journal: J Immunol. 2010 Oct 15;185(8):4912-20.
Title: IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.
Author: Zaki, Mohammad Hasan|Vogel, Peter|Body-Malapel, Mathilde|Lamkanfi, Mohamed|Kanneganti, Thirumala-Devi
PMID: 20855874
Journal: Trends Immunol. 2011 Apr;32(4):171-9.
Title: The Nlrp3 inflammasome: contributions to intestinal homeostasis.
Author: Zaki, Md Hasan|Lamkanfi, Mohamed|Kanneganti, Thirumala-Devi
PMID: 21388882
Journal: Carcinogenesis. 2012 Nov;33(11):2126-34.
Title: Genetic variation and alterations of genes involved in NFkappaB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer.
Author: Ungerback, Jonas|Belenki, Dimitri|Jawad ul-Hassan, Aksa|Fredrikson, Mats|Fransen, Karin|Elander, Nils|Verma, Deepti|Soderkvist, Peter
PMID: 22843550
Journal: Nature. 2012 Nov 8;491(7423):259-63.
Title: IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
Author: Huber, Samuel|Gagliani, Nicola|Zenewicz, Lauren A|Huber, Francis J|Bosurgi, Lidia|Hu, Bo|Hedl, Matija|Zhang, Wei|O'Connor, William Jr|Murphy, Andrew J|Valenzuela, David M|Yancopoulos, George D|Booth, Carmen J|Cho, Judy H|Ouyang, Wenjun|Abraham, Clara|Flav
PMID: 23075849
Journal: Cancer Biol Ther. 2014 Apr;15(4):452-62.
Title: Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer.
Author: Overley-Adamson, Beth|Artlett, Carol M|Stephens, Connie|Sassi-Gaha, Sihem|Weis, Ransome D|Thacker, James D
PMID: 24496016
Journal: J Pathol. 2014 Aug;233(4):321-30.
Title: NLRPs, microbiota, and gut homeostasis: unravelling the connection.
Author: Zambetti, Lia Paola|Mortellaro, Alessandra
PMID: 24740681
Journal: Bull Cancer. 2014 Jun;101(6):605-7.
Title: [Impact of chemotherapies on immunosuppression and discovery of new therapeutic targets].
Author: Bruchard, Melanie|Ghiringhelli, Francois
PMID: 24899072
Journal: Cell Death Differ. 2014 Dec;21(12):1914-24.
Title: Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells.
Author: Derangere, V|Chevriaux, A|Courtaut, F|Bruchard, M|Berger, H|Chalmin, F|Causse, S Z|Limagne, E|Vegran, F|Ladoire, S|Simon, B|Boireau, W|Hichami, A|Apetoh, L|Mignot, G|Ghiringhelli, F|Rebe, C
PMID: 25124554
Journal: Oncotarget. 2015 Oct 20;6(32):33456-69.
Title: Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components.
Author: Liu, Rongrong|Truax, Agnieszka D|Chen, Liang|Hu, Peizhen|Li, Zengshan|Chen, Jun|Song, Chaojun|Chen, Lihua|Ting, Jenny Pan-Yun
PMID: 26378020
Journal: Immunity. 2015 Oct 20;43(4):751-63.
Title: The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity.
Author: Dupaul-Chicoine, Jeremy|Arabzadeh, Azadeh|Dagenais, Maryse|Douglas, Todd|Champagne, Claudia|Morizot, Alexandre|Rodrigue-Gervais, Ian Gael|Breton, Valerie|Colpitts, Sara L|Beauchemin, Nicole|Saleh, Maya
PMID: 26384545
Journal: Genet Mol Res. 2015 Oct 30;14(4):13968-80.
Title: NLRP3 rs35829419 polymorphism is associated with increased susceptibility to multiple diseases in humans.
Author: Zhang, Q|Fan, H W|Zhang, J Z|Wang, Y M|Xing, H J
PMID: 26535712
Journal: Biochem Pharmacol. 2016 Apr 1;105:42-54.
Title: Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome.
Author: Du, Qianming|Wang, Qing|Fan, Huimin|Wang, Jianing|Liu, Xiuting|Wang, Hong|Wang, Yajing|Hu, Rong
PMID: 26921636
Journal: Exp Cell Res. 2016 Mar 15;342(2):184-92.
Title: Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells.
Author: Wang, Hong|Wang, Yajing|Du, Qianming|Lu, Ping|Fan, Huimin|Lu, Jinrong|Hu, Rong
PMID: 26968633
Journal: Curr Opin Oncol. 2017 Jan;29(1):35-40.
Title: The multifaceted roles of inflammasome proteins in cancer.
Author: Petrilli, Virginie
PMID: 27875342
Journal: Free Radic Biol Med. 2017 Mar;104:75-103.
Title: Redox signaling in the gastrointestinal tract.
Author: Perez, Salvador|Talens-Visconti, Raquel|Rius-Perez, Sergio|Finamor, Isabela|Sastre, Juan
PMID: 28062361
Journal: Cancer Immunol Res. 2017 Feb;5(2):94-99.
Title: Inflammasomes and Cancer.
Author: Karki, Rajendra|Man, Si Ming|Kanneganti, Thirumala-Devi
PMID: 28093447
Journal: Curr Pharm Des. 2017;23(16):2321-2327.
Title: NLRP3 Inhibitors as Potential Therapeutic Agents for Treatment of Inflammatory Bowel Disease.
Author: Perera, Agampodi Promoda|Kunde, Dale|Eri, Rajaraman
PMID: 28155620
Journal: Immunopharmacol Immunotoxicol. 2017 Aug;39(4):199-210.
Title: The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.
Author: Blom, Kristin|Senkowski, Wojciech|Jarvius, Malin|Berglund, Malin|Rubin, Jenny|Lenhammar, Lena|Parrow, Vendela|Andersson, Claes|Loskog, Angelica|Fryknas, Marten|Nygren, Peter|Larsson, Rolf
PMID: 28472897
Journal: Nat Commun. 2017 Dec 1;8(1):1896.
Title: Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis.
Author: Yao, Xiaomin|Zhang, Chenhong|Xing, Yue|Xue, Guang|Zhang, Qianpeng|Pan, Fengwei|Wu, Guojun|Hu, Yingxin|Guo, Qiuhong|Lu, Ailing|Zhang, Xiaoming|Zhou, Rongbin|Tian, Zhigang|Zeng, Benhua|Wei, Hong|Strober, Warren|Zhao, Liping|Meng, Guangxun
PMID: 29196621
Journal: Oncoimmunology. 2017 Sep 21;7(1):e1375640.
Title: Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.
Author: Zhao, Yue|Guo, Qinglong|Zhao, Kai|Zhou, Yuxin|Li, Wenjun|Pan, Chuyue|Qiang, Lei|Li, Zhiyu|Lu, Na
PMID: 29296531
Journal: Cancer Res Treat. 2018 Aug 1. pii: crt.2018.060.
Title: Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development.
Author: Son, Hee Jin|Sohn, Sung Hwa|Kim, Nayoung|Lee, Ha-Na|Lee, Sun Min|Nam, Ryoung Hee|Park, Ji Hyun|Song, Chin-Hee|Shin, Eun|Na, Hee Young|Kim, Joo Sung|Lee, Dong Ho|Surh, Young-Joon
PMID: 30064198
Journal: Mamm Genome. 2018 Sep 11. pii: 10.1007/s00335-018-9783-2.
Title: NLRP3 inflammasome in colitis and colitis-associated colorectal cancer.
Author: Perera, Agampodi Promoda|Sajnani, Karishma|Dickinson, Joanne|Eri, Rajaraman|Korner, Heinrich
PMID: 30206651
Journal: Food Funct. 2018 Oct 19.
Title: Deoxycholic acid disrupts the intestinal mucosal barrier and promotes intestinal tumorigenesis.
Author: Liu, Li|Dong, Wenxiao|Wang, Sinan|Zhang, Yujie|Liu, Tianyu|Xie, Runxiang|Wang, Bangmao|Cao, Hailong
PMID: 30339173