Primary Site >> Pancreatic Cancer

Gene >> NFKBIA

Journal: J Surg Res. 1999 May 1;83(1):56-61.
Title: Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells.
Author: McDade, T P|Perugini, R A|Vittimberga, F J Jr|Carrigan, R C|Callery, M P
PMID: 10210643
Journal: Clin Cancer Res. 1999 Jan;5(1):119-27.
Title: The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.
Author: Wang, W|Abbruzzese, J L|Evans, D B|Larry, L|Cleary, K R|Chiao, P J
PMID: 9918209
Journal: Oncogene. 1999 Aug 12;18(32):4554-63.
Title: Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA.
Author: Wang, W|Abbruzzese, J L|Evans, D B|Chiao, P J
PMID: 10467400
Journal: Oncogene. 2000 Apr 27;19(18):2233-9.
Title: Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kappaB.
Author: Kajino, S|Suganuma, M|Teranishi, F|Takahashi, N|Tetsuka, T|Ohara, H|Itoh, M|Okamoto, T
PMID: 10822373
Journal: J Interferon Cytokine Res. 2000 Nov;20(11):935-46.
Title: Molecular regulation of constitutive expression of interleukin-8 in human pancreatic adenocarcinoma.
Author: Le, X|Shi, Q|Wang, B|Xiong, Q|Qian, C|Peng, Z|Li, X C|Tang, H|Abbruzzese, J L|Xie, K
PMID: 11096450
Journal: Oncogene. 2001 Feb 15;20(7):859-68.
Title: Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin.
Author: Arlt, A|Vorndamm, J|Breitenbroich, M|Folsch, U R|Kalthoff, H|Schmidt, W E|Schafer, H
PMID: 11314019
Journal: Biochem J. 2001 Jun 1;356(Pt 2):525-30.
Title: Inhibitor of nuclear factor-kappaB induction by cAMP antagonizes interleukin-1-induced human macrophage-colony-stimulating-factor expression.
Author: Kamthong, P J|Wu , M
PMID: 11368781
Journal: J Gastrointest Surg. 2001 Nov-Dec;5(6):603-12; discussion 612-3.
Title: PI-3' kinase and NF-kappaB cross-signaling in human pancreatic cancer cells.
Author: Shah, S A|Potter, M W|Hedeshian, M H|Kim, R D|Chari, R S|Callery, M P
PMID: 12086898
Journal: Cancer Res. 2002 Feb 1;62(3):910-6.
Title: Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines.
Author: Arlt, Alexander|Vorndamm, Jens|Muerkoster, Susanne|Yu, Honggang|Schmidt, Wolfgang E|Folsch, Ulrich R|Schafer, Heiner
PMID: 11830551
Journal: Surgery. 2002 Aug;132(2):127-34.
Title: Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death.
Author: Thomas, Robert P|Farrow, Buckminster J|Kim, Sunghoon|May, Michael J|Hellmich, Mark R|Evers, B Mark
PMID: 12219002
Journal: Ai Zheng. 2002 Jun;21(6):663-7.
Title: [Expression of NF-kappa B in human bladder cancer and its clinical significance].
Author: Xie, Dong-hua|Tang, Xiao-da|Xia, Shu-jie|Tan, Jian-ming|Wang, Xiang-hui|Cai, Yong
PMID: 12452071
Journal: Oncogene. 2003 Mar 6;22(9):1365-70.
Title: Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.
Author: Fujioka, Shuichi|Sclabas, Guido M|Schmidt, Christian|Niu, Jiangong|Frederick, Wayne A|Dong, Qiang G|Abbruzzese, James L|Evans, Douglas B|Baker, Cheryl|Chiao, Paul J
PMID: 12618762
Journal: Oncogene. 2003 May 22;22(21):3243-51.
Title: Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death.
Author: Arlt, Alexander|Gehrz, Andre|Muerkoster, Susanne|Vorndamm, Jens|Kruse, Marie-Luise|Folsch, Ulrich R|Schafer, Heiner
PMID: 12761494
Journal: Int J Cancer. 2003 Jul 20;105(6):735-46.
Title: Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer.
Author: Liptay, Susanne|Weber, Christoph K|Ludwig, Leopold|Wagner, Martin|Adler, Guido|Schmid, Roland M
PMID: 12767057
Journal: Cancer Sci. 2003 May;94(5):467-72.
Title: Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor.
Author: Sato, Toshiyuki|Odagiri, Hiroki|Ikenaga, Shojiro-Kazunori|Maruyama, Masateru|Sasaki, Mutsuo
PMID: 12824895
Journal: Int J Cancer. 2004 Jan 10;108(2):181-8.
Title: NF-kappaB activity blockade impairs the angiogenic potential of human pancreatic cancer cells.
Author: Xiong, Henry Q|Abbruzzese, James L|Lin, Edward|Wang, Liwei|Zheng, Leizhen|Xie, Keping
PMID: 14639600
Journal: J Surg Res. 2004 May 1;118(1):9-14.
Title: Increased expression of NF-kappa B subunits in human pancreatic cancer cells.
Author: Chandler, Nicole M|Canete, Jonathan J|Callery, Mark P
PMID: 15093710
Journal: J Biol Chem. 2004 Nov 26;279(48):50455-64.
Title: N-Acetyl-L-cysteine enhances apoptosis through inhibition of nuclear factor-kappaB in hypoxic murine embryonic fibroblasts.
Author: Qanungo, Suparna|Wang, Mi|Nieminen, Anna-Liisa
PMID: 15375156
Journal: Mol Cancer Ther. 2005 Apr;4(4):587-94.
Title: Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells.
Author: Yip-Schneider, Michele T|Nakshatri, Harikrishna|Sweeney, Christopher J|Marshall, Mark S|Wiebke, Eric A|Schmidt, C Max
PMID: 15827332
Journal: Int J Cancer. 2006 May 15;118(10):2405-11.
Title: GADD45alpha is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability.
Author: Schneider, Gunter|Weber, Andreas|Zechner, Ulrich|Oswald, Franz|Friess, Helmut M|Schmid, Roland M|Liptay, Susanne
PMID: 16353139
Journal: Mol Cancer Ther. 2006 Sep;5(9):2251-60.
Title: Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.
Author: Khanbolooki, Sanaz|Nawrocki, Steffan T|Arumugam, Thiruvengadam|Andtbacka, Robert|Pino, Maria S|Kurzrock, Razelle|Logsdon, Craig D|Abbruzzese, James L|McConkey, David J
PMID: 16985059
Journal: Mol Cancer Res. 2006 Oct;4(10):715-28.
Title: Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.
Author: Braeuer, Susanne J|Buneker, Chirlei|Mohr, Andrea|Zwacka, Ralf Michael
PMID: 17050666
Journal: J Biol Chem. 2007 Mar 2;282(9):6001-11.
Title: Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors.
Author: Niu, Jiangong|Chang, Zhe|Peng, Bailu|Xia, Qianghua|Lu, Weiqin|Huang, Peng|Tsao, Ming-Sound|Chiao, Paul J
PMID: 17200110
Journal: Cancer. 2007 May 15;109(10):2142-53.
Title: Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
Author: Uwagawa, Tadashi|Li, Zhongkui|Chang, Zhe|Xia, Qianghua|Peng, Bailu|Sclabas, Guido M|Ishiyama, Satoshi|Hung, Mien-Chie|Evans, Douglas B|Abbruzzese, James L|Chiao, Paul J
PMID: 17410536
Journal: Cancer Res. 2007 Aug 1;67(15):7266-74.
Title: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.
Author: Rengifo-Cam, William|Umar, Shahid|Sarkar, Shubhashish|Singh, Pomila
PMID: 17671195
Journal: Cancer Res. 2008 Nov 15;68(22):9519-24.
Title: IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model.
Author: Zhang, Yixian|Gavriil, Maria|Lucas, Judy|Mandiyan, Sreekala|Follettie, Max|Diesl, Veronica|Sum, Fuk-Wah|Powell, Dennis|Haney, Steve|Abraham, Robert|Arndt, Kim
PMID: 19010928
Journal: J Immunol. 2008 Dec 15;181(12):8441-9.
Title: Decoy receptor 3 expression in AsPC-1 human pancreatic adenocarcinoma cells via the phosphatidylinositol 3-kinase-, Akt-, and NF-kappa B-dependent pathway.
Author: Chen, Pei-Hsuan|Yang, Chia-Ron
PMID: 19050262
Journal: Cancer Res. 2009 Jun 15;69(12):4983-91.
Title: N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression.
Author: Hosoi, Fumihito|Izumi, Hiroto|Kawahara, Akihiko|Murakami, Yuichi|Kinoshita, Hisafumi|Kage, Masayoshi|Nishio, Kazuto|Kohno, Kimitoshi|Kuwano, Michihiko|Ono, Mayumi
PMID: 19491262
Journal: Int J Cancer. 2009 Nov 15;125(10):2465-73.
Title: Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB.
Author: Murtaza, Imtiyaz|Adhami, Vaqar Mustafa|Hafeez, Bilal Bin|Saleem, Mohammad|Mukhtar, Hasan
PMID: 19670328
Journal: J Surg Oncol. 2009 Dec 15;100(8):725-31.
Title: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway.
Author: Ikebe, Mio|Kitaura, Yoshiki|Nakamura, Masafumi|Tanaka, Haruo|Yamasaki, Akio|Nagai, Shuntaro|Wada, Junji|Yanai, Kosuke|Koga, Kenichiro|Sato, Norihiro|Kubo, Makoto|Tanaka, Masao|Onishi, Hideya|Katano, Mitsuo
PMID: 19722233
Journal: Cancer Res. 2010 Apr 15;70(8 Suppl):5703.
Title: Up-regulation of miR-146a contributes to the inhibition of invasion of pancreatic cancer cells.
Author: Li, Yiwei|VandenBoom, Timothy G 2nd|Wang, Zhiwei|Kong, Dejuan|Ali, Shadan|Philip, Philip A|Sarkar, Fazlul H
PMID: 25242818
Journal: Cancer Prev Res (Phila). 2010 Nov;3(11):1427-34.
Title: Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.
Author: Liby, Karen T|Royce, Darlene B|Risingsong, Renee|Williams, Charlotte R|Maitra, Anirban|Hruban, Ralph H|Sporn, Michael B
PMID: 20959520
Journal: Oncol Rep. 2010 Oct;24(4):843-50.
Title: Anti-tumor effect by inhibition of NF-kappaB activation using nafamostat mesilate for pancreatic cancer in a mouse model.
Author: Furukawa, Kenei|Iida, Tomonori|Shiba, Hiroaki|Fujiwara, Yuki|Uwagawa, Tadashi|Shimada, Yohta|Misawa, Takeyuki|Ohashi, Toya|Yanaga, Katsuhiko
PMID: 20811662
Journal: Biol Pharm Bull. 2010;33(8):1261-7.
Title: Gemcitabine resistance induced by interaction between alternatively spliced segment of tenascin-C and annexin A2 in pancreatic cancer cells.
Author: Gong, Xiao-Guang|Lv, Yun-Fu|Li, Xin-Qiu|Xu, Fu-Guo|Ma, Qing-Yong
PMID: 20686216
Journal: Biochem Biophys Res Commun. 2010 May 28;396(2):376-81.
Title: Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells.
Author: Murakami, Yuichi|Hosoi, Fumihito|Izumi, Hiroto|Maruyama, Yuichiro|Ureshino, Hiroki|Watari, Kosuke|Kohno, Kimitoshi|Kuwano, Michihiko|Ono, Mayumi
PMID: 20416281
Journal: Mol Cancer. 2010 Apr 6;9:73.
Title: Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway.
Author: Li, Chenghai|Yang, Zhengfeng|Zhai, Chunyan|Qiu, Wenwei|Li, Dali|Yi, Zhengfang|Wang, Lei|Tang, Jie|Qian, Min|Luo, Jian|Liu, Mingyao
PMID: 20367887
Journal: Cancer Lett. 2010 Sep 28;295(2):214-28.
Title: NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.
Author: Maier, Harald J|Schmidt-Strassburger, Uta|Huber, Margit A|Wiedemann, Eva M|Beug, Hartmut|Wirth, Thomas
PMID: 20350779
Journal: Cancer Res. 2010 Feb 15;70(4):1486-95.
Title: miR-146a suppresses invasion of pancreatic cancer cells.
Author: Li, Yiwei|Vandenboom, Timothy G 2nd|Wang, Zhiwei|Kong, Dejuan|Ali, Shadan|Philip, Philip A|Sarkar, Fazlul H
PMID: 20124483
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G275-82.
Title: TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells.
Author: Chow, Jimmy Y C|Ban, Makiko|Wu, Helen L|Nguyen, Flang|Huang, Mei|Chung, Heekyung|Dong, Hui|Carethers, John M
PMID: 19940030
Journal: Acta Pharmacol Sin. 2010 Jun;31(6):741-5.
Title: Gemcitabine combined with gum mastic causes potent growth inhibition and apoptosis of pancreatic cancer cells.
Author: Huang, Xin-yu|Wang, Hong-cheng|Yuan, Zhou|Li, Ang|He, Mei-lan|Ai, Kai-xing|Zheng, Qi|Qin, Huan-long
PMID: 20523344
Journal: J Cell Physiol. 2011 Feb;226(2):456-68.
Title: Altered intracellular calcium fluxes in pancreatic cancer induced diabetes mellitus: Relevance of the S100A8 N-terminal peptide (NT-S100A8).
Author: Basso, Daniela|Greco, Eliana|Padoan, Andrea|Fogar, Paola|Scorzeto, Michele|Fadi, Elisa|Bozzato, Dania|Moz, Stefania|Navaglia, Filippo|Zambon, Carlo-Federico|Seraglia, Roberta|De Carlo, Eugenio|Valerio, Anna|Reggiani, Carlo|Pedrazzoli, Sergio|Plebani, Mari
PMID: 20717964
Journal: Cancer Lett. 2011 May 28;304(2):117-27.
Title: PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKalpha and sustained activation of the NF-kappaB pathway.
Author: Li, Wei|Chen, Zheng|Zong, Yang|Gong, Feiran|Zhu, Yi|Zhu, Yunxia|Lv, Jinghuan|Zhang, Jingjing|Xie, Li|Sun, Yujie|Miao, Yi|Tao, Min|Han, Xiao|Xu, Zekuan
PMID: 21376459
Journal: J Hepatobiliary Pancreat Sci. 2011 Sep;18(5):731-9.
Title: Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition.
Author: Fujiwara, Yuki|Furukawa, Kenei|Haruki, Koichiro|Shimada, Yohta|Iida, Tomonori|Shiba, Hiroaki|Uwagawa, Tadashi|Ohashi, Toya|Yanaga, Katsuhiko
PMID: 21484229
Journal: Neoplasia. 2011 Dec;13(12):1162-70.
Title: Requirement of nuclear factor kappaB for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-induced apoptosis.
Author: Stadel, Dominic|Cristofanon, Silvia|Abhari, Behnaz Ahangarian|Deshayes, Kurt|Zobel, Kerry|Vucic, Domagoj|Debatin, Klaus-Michael|Fulda, Simone
PMID: 22241962
Journal: Cancer Lett. 2011 May 28;304(2):117-27.
Title: PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKalpha and sustained activation of the NF-kappaB pathway.
Author: Li, Wei|Chen, Zheng|Zong, Yang|Gong, Feiran|Zhu, Yi|Zhu, Yunxia|Lv, Jinghuan|Zhang, Jingjing|Xie, Li|Sun, Yujie|Miao, Yi|Tao, Min|Han, Xiao|Xu, Zekuan
PMID: 26904954
Journal: J Gastrointest Surg. 2012 Jul;16(7):1333-40.
Title: Dimethylamino parthenolide enhances the inhibitory effects of gemcitabine in human pancreatic cancer cells.
Author: Holcomb, Bryan K|Yip-Schneider, Michele T|Waters, Joshua A|Beane, Joal D|Crooks, Peter A|Schmidt, C Max
PMID: 22618517
Journal: J Biol Chem. 2012 Nov 9;287(46):39115-24.
Title: CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor kappaB: implications for bidirectional tumor-stromal interactions.
Author: Singh, Ajay P|Arora, Sumit|Bhardwaj, Arun|Srivastava, Sanjeev K|Kadakia, Madhavi P|Wang, Bin|Grizzle, William E|Owen, Laurie B|Singh, Seema
PMID: 22995914
Journal: Cancer Gene Ther. 2013 Feb;20(2):133-40.
Title: Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis.
Author: Kulu, Y|Kawasaki, H|Donahue, J M|Kasuya, H|Cusack, J C|Choi, E W|Kuruppu, D K|Fuchs, B C|Tanabe, K K
PMID: 23348635
Journal: Cancer Lett. 2013 Jun 1;333(1):89-95.
Title: Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-kappaB activation for pancreatic cancer.
Author: Gocho, Takeshi|Uwagawa, Tadashi|Furukawa, Kenei|Haruki, Koichiro|Fujiwara, Yuki|Iwase, Ryota|Misawa, Takeyuki|Ohashi, Toya|Yanaga, Katsuhiko
PMID: 23348695
Journal: Clin Cancer Res. 2013 Apr 15;19(8):2025-35.
Title: Targeting the NF-kappaB and mTOR pathways with a quinoxaline urea analog that inhibits IKKbeta for pancreas cancer therapy.
Author: Radhakrishnan, Prakash|Bryant, Vashti C|Blowers, Elizabeth C|Rajule, Rajkumar N|Gautam, Nagsen|Anwar, Muhammad M|Mohr, Ashley M|Grandgenett, Paul M|Bunt, Stephanie K|Arnst, Jamie L|Lele, Subodh M|Alnouti, Yazen|Hollingsworth, Michael A|Natarajan, Amarnath
PMID: 23444213
Journal: J Biol Chem. 2013 Jul 19;288(29):21197-207.
Title: An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor kappaB- and hypoxia-inducible factor 1alpha-mediated up-regulation of CXCR4.
Author: Arora, Sumit|Bhardwaj, Arun|Singh, Seema|Srivastava, Sanjeev K|McClellan, Steven|Nirodi, Chaitanya S|Piazza, Gary A|Grizzle, William E|Owen, Laurie B|Singh, Ajay P
PMID: 23740244
Journal: PLoS One. 2013 Oct 11;8(10):e77126.
Title: Digitoflavone inhibits IkappaBalpha kinase and enhances apoptosis induced by TNFalpha through downregulation of expression of nuclear factor kappaB-regulated gene products in human pancreatic cancer cells.
Author: Cai, Xueting|Lu, Wuguang|Yang, Yang|Yang, Jie|Ye, Juan|Gu, Zhenhua|Hu, Chunping|Wang, Xiaoning|Cao, Peng
PMID: 24146961
Journal: PLoS One. 2014 Feb 4;9(2):e87897.
Title: MiR-196a promotes pancreatic cancer progression by targeting nuclear factor kappa-B-inhibitor alpha.
Author: Huang, Fengting|Tang, Jian|Zhuang, Xiaohong|Zhuang, Yanyan|Cheng, Wenjie|Chen, Wenbo|Yao, Herui|Zhang, Shineng
PMID: 24504166
Journal: Oncotarget. 2014 Sep 30;5(18):8778-89.
Title: p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-kappaB pathway.
Author: Tyagi, Nikhil|Bhardwaj, Arun|Singh, Ajay P|McClellan, Steven|Carter, James E|Singh, Seema
PMID: 25238288
Journal: Can J Physiol Pharmacol. 2014 Apr;92(4):324-9.
Title: Apoptosis induced by microwave radiation in pancreatic cancer JF305 cells.
Author: Zhu, Wenhe|Zhang, Wei|Wang, Huiyan|Xu, Junjie|Li, Yan|Lv, Shijie
PMID: 24708215
Journal: Cell Death Dis. 2014 Mar 27;5:e1142.
Title: Differential activity of GSK-3 isoforms regulates NF-kappaB and TRAIL- or TNFalpha induced apoptosis in pancreatic cancer cells.
Author: Zhang, J-S|Herreros-Villanueva, M|Koenig, A|Deng, Z|de Narvajas, A A-M|Gomez, T S|Meng, X|Bujanda, L|Ellenrieder, V|Li, X K|Kaufmann, S H|Billadeau, D D
PMID: 24675460
Journal: Oncogenesis. 2014 Mar 17;3:e92.
Title: S100P antibody-mediated therapy as a new promising strategy for the treatment of pancreatic cancer.
Author: Dakhel, S|Padilla, L|Adan, J|Masa, M|Martinez, J M|Roque, L|Coll, T|Hervas, R|Calvis, C|Messeguer, R|Mitjans, F|Hernandez, J L
PMID: 24637492
Journal: Surgery. 2015 Oct;158(4):881-8; discussion 888-9.
Title: Targeted nuclear factor-kappaB suppression enhances gemcitabine response in human pancreatic tumor cell line murine xenografts.
Author: Waters, Joshua A|Matos, Jesus|Yip-Schneider, Michele|Aguilar-Saavedra, Juan R|Crean, Colin D|Beane, Joal D|Dumas, Ryan P|Suvannasankha, Attaya|Schmidt, C Max
PMID: 26209568
Journal: J Pineal Res. 2016 Jan;60(1):27-38.
Title: Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-kappaB activation.
Author: Ju, Huai-Qiang|Li, Hao|Tian, Tian|Lu, Yun-Xin|Bai, Long|Chen, Le-Zong|Sheng, Hui|Mo, Hai-Yu|Zeng, Jun-Bo|Deng, Wuguo|Chiao, Paul J|Xu, Rui-Hua
PMID: 26445000
Journal: Oncogene. 2016 Dec 8;35(49):6319-6329.
Title: RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.
Author: Hein, A L|Post, C M|Sheinin, Y M|Lakshmanan, I|Natarajan, A|Enke, C A|Batra, S K|Ouellette, M M|Yan, Y
PMID: 27181206
Journal: Cancer Lett. 2016 Sep 28;380(1):87-97.
Title: Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis.
Author: Lu, Yun-Xin|Ju, Huai-Qiang|Wang, Feng|Chen, Le-Zong|Wu, Qi-Nian|Sheng, Hui|Mo, Hai-Yu|Pan, Zhi-Zhong|Xie, Dan|Kang, Tie-Bang|Chen, Gong|Yun, Jing-Ping|Zeng, Zhao-Lei|Xu, Rui-Hua
PMID: 27322737
Journal: J Nanobiotechnology. 2016 Jul 11;14(1):57.
Title: A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies.
Author: Bisht, Savita|Schlesinger, Martin|Rupp, Alexander|Schubert, Rolf|Nolting, Jens|Wenzel, Jorg|Holdenrieder, Stefan|Brossart, Peter|Bendas, Gerd|Feldmann, Georg
PMID: 27401816
Journal: Cell Signal. 2016 Nov;28(11):1652-62.
Title: Negative control of TRAIL-R1 signaling by transforming growth factor beta1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.
Author: Radke, David I|Ungefroren, Hendrik|Helm, Ole|Voigt, Susann|Alp, Gokhan|Braun, Hendrik|Hubner, Sebastian|Dilchert, Janine|Sebens, Susanne|Adam, Dieter|Kalthoff, Holger|Trauzold, Anna
PMID: 27492861
Journal: ACS Appl Mater Interfaces. 2016 Nov 23;8(46):31806-31812.
Title: Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Human Cancer Cells through Reactive Oxygen Species-Mediated NF-kappaB Activations.
Author: Yuan, Ru|Xu, Huanli|Liu, Xiaohui|Tian, Ye|Li, Cong|Chen, Xiaoliang|Su, Shuonan|Perelshtein, Ilana|Gedanken, Aharon|Lin, Xiukun
PMID: 27791350
Journal: PLoS One. 2017 Feb 24;12(2):e0172689.
Title: RAC1b overexpression stimulates proliferation and NF-kB-mediated anti-apoptotic signaling in thyroid cancer cells.
Author: Faria, Marcia|Matos, Paulo|Pereira, Teresa|Cabrera, Rafael|Cardoso, Bruno A|Bugalho, Maria Joao|Silva, Ana Luisa
PMID: 28234980
Journal: Tumour Biol. 2017 Jul;39(7):1010428317706917.
Title: Sporamin induces apoptosis and inhibits NF-kappaB activation in human pancreatic cancer cells.
Author: Qian, Cuijuan|Chen, Xiaoying|Qi, Yongxiao|Zhong, Sheng|Gao, Xinyan|Zheng, Wenjun|Mao, Zhixiang|Yao, Jun
PMID: 28714369
Journal: Sci Rep. 2017 Jul 19;7(1):5925.
Title: Centrosomal protein 55 activates NF-kappaB signalling and promotes pancreatic cancer cells aggressiveness.
Author: Peng, Tao|Zhou, Wei|Guo, Feng|Wu, He-Shui|Wang, Chun-You|Wang, Li|Yang, Zhi-Yong
PMID: 28724890
Journal: Oncogene. 2018 Feb 15;37(7):912-923.
Title: SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer.
Author: Zhou, H|Qin, Y|Ji, S|Ling, J|Fu, J|Zhuang, Z|Fan, X|Song, L|Yu, X|Chiao, P J
PMID: 29059173
Journal: Life Sci. 2018 Jan 1;192:55-61.
Title: Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-kappaB/MMPs pathway.
Author: Huang, Minna|Xin, Wen
PMID: 29155301