Primary Site >> Colorectal Cancer

Gene >> NFKBIA

Journal: Oncogene. 1998 Mar 5;16(9):1187-95.
Title: Nuclear factor - kappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug.
Author: Hellin, A C|Calmant, P|Gielen, J|Bours, V|Merville, M P
PMID: 9528861
Journal: J Clin Invest. 1999 Aug;104(4):383-9.
Title: A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response.
Author: Su, C G|Wen, X|Bailey, S T|Jiang, W|Rangwala, S M|Keilbaugh, S A|Flanigan, A|Murthy, S|Lazar, M A|Wu, G D
PMID: 10449430
Journal: Shock. 2000 Jan;13(1):8-13.
Title: IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling.
Author: Parikh, A A|Moon, M R|Pritts, T A|Fischer, J E|Szabo, C|Hasselgren, P O|Salzman, A L
PMID: 10638662
Journal: Cancer Res. 2000 Apr 1;60(7):2007-17.
Title: Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways.
Author: Remacle-Bonnet, M M|Garrouste, F L|Heller, S|Andre, F|Marvaldi, J L|Pommier, G J
PMID: 10766192
Journal: Biol Pharm Bull. 2000 Apr;23(4):420-6.
Title: Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis.
Author: Han, S Y|Choung, S Y|Paik, I S|Kang, H J|Choi, Y H|Kim, S J|Lee, M O
PMID: 10784420
Journal: Cancer Res. 2000 May 1;60(9):2323-30.
Title: Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation.
Author: Cusack, J C Jr|Liu, R|Baldwin, A S Jr
PMID: 10811101
Journal: Biochem Biophys Res Commun. 2000 Jul 14;273(3):853-8.
Title: Activation of NF-kappaB binding in HT-29 colon cancer cells by inhibition of phosphatidylinositol 3-kinase.
Author: Wang, Q|Kim, S|Wang, X|Evers, B M
PMID: 10891336
Journal: Mol Carcinog. 2000 Sep;29(1):25-36.
Title: IkappaBbeta-related proteins in normal and transformed colonic epithelial cells.
Author: Inan, M S|Place, R|Tolmacheva, V|Wang, Q S|Hubbard, A K|Rosenberg, D W|Giardina, C
PMID: 11020244
Journal: Cancer Res. 2001 Jan 15;61(2):433-8.
Title: Assessment of tumor necrosis factor receptor and Fas signaling pathways by transcriptional profiling.
Author: Manos, E J|Jones, D A
PMID: 11212226
Journal: Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):183-93.
Title: Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.
Author: Russo, S M|Tepper, J E|Baldwin, A S Jr|Liu, R|Adams, J|Elliott, P|Cusack, J C Jr
PMID: 11316563
Journal: J Biol Chem. 2001 May 25;276(21):18223-8. Epub 2001 Mar 16.
Title: IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal.
Author: Ji, C|Kozak, K R|Marnett, L J
PMID: 11359792
Journal: Biochem Pharmacol. 2002 Nov 15;64(10):1439-45.
Title: 5-Fluorouracil inhibits nitric oxide production through the inactivation of IkappaB kinase in stomach cancer cells.
Author: Jung, In Duk|Yang, So Young|Park, Chang Gyo|Lee, Kyung Bok|Kim, Jong Seung|Lee, Seok Yong|Han, Jeung Whan|Lee, Hyang Woo|Lee, Hoi Young
PMID: 12417257
Journal: Oncogene. 2003 Jan 9;22(1):90-7.
Title: NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells.
Author: Bentires-Alj, Mohamed|Barbu, Veronique|Fillet, Marianne|Chariot, Alain|Relic, Biserka|Jacobs, Nathalie|Gielen, Jacques|Merville, Marie-Paule|Bours, Vincent
PMID: 12527911
Journal: Int J Cancer. 2003 Apr 20;104(4):504-11.
Title: Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines.
Author: Wang, Weiguang|McLeod, Howard L|Cassidy, James
PMID: 12584750
Journal: Cancer Sci. 2003 Aug;94(8):745-50.
Title: Adenovirus-mediated gene transduction of truncated I kappa B alpha enhances radiosensitivity in human colon cancer cells.
Author: Mukogawa, Tomohide|Koyama, Fumikazu|Tachibana, Masaaki|Takayanagi, Atsushi|Shimizu, Nobuyoshi|Fujii, Hisao|Ueno, Masato|Matsumoto, Hiroshi|Takeuchi, Taku|Nakajima, Yoshiyuki
PMID: 12901803
Journal: Cell Death Differ. 2003 Sep;10(9):1078-89.
Title: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Author: Hermisson, M|Weller, M
PMID: 12934082
Journal: Korean J Gastroenterol. 2004 Mar;43(3):176-85.
Title: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8].
Author: Lee, Dong Ki|Park, Sun Young|Baik, Soon Koo|Kwon, Sang Ok|Chung, Jun Mo|Oh, Eok-Soo|Kim, Hyun Soo
PMID: 15034288
Journal: J Biol Chem. 2004 Jun 18;279(25):26019-27. Epub 2004 Mar 26.
Title: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling.
Author: Nho, Chu Won|O'Dwyer, Peter J
PMID: 15047705
Journal: Pharm Res. 2004 Apr;21(4):661-70.
Title: Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway.
Author: Jeong, Woo-Sik|Kim, In-Wha|Hu, Rong|Kong, Ah-Ng Tony
PMID: 15139523
Journal: Cancer Lett. 2004 Jul 8;210(1):1-6.
Title: Antiproliferative crude soy saponin extract modulates the expression of IkappaBalpha, protein kinase C, and cyclooxygenase-2 in human colon cancer cells.
Author: Kim, Hwa-Young|Yu, Rina|Kim, Jeong-Sang|Kim, Young-Kyoon|Sung, Mi-Kyung
PMID: 15172114
Journal: Br J Cancer. 2004 Jul 19;91(2):381-8.
Title: Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis.
Author: Din, F V N|Dunlop, M G|Stark, L A
PMID: 15188000
Journal: J Surg Res. 2004 Aug;120(2):178-88.
Title: Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer.
Author: Voboril, Rene|Hochwald, Steven N|Li, Jing|Brank, Adam|Weberova, Jana|Wessels, Frank|Moldawer, Lyle L|Camp, E Ramsay|MacKay, Sally L D
PMID: 15234211
Journal: J Natl Cancer Inst. 2004 Aug 4;96(15):1161-70.
Title: Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer.
Author: Ougolkov, Andrei|Zhang, Bin|Yamashita, Kaname|Bilim, Vladimir|Mai, Masayoshi|Fuchs, Serge Y|Minamoto, Toshinari
PMID: 15292388
Journal: Oncol Rep. 2005 Mar;13(3):473-6.
Title: Mapping of the critical region of mitogene-inducible gene-6 for NF-kappaB activation.
Author: Mabuchi, Reiko|Sasazuki, Takehiko|Shirasawa, Senji
PMID: 15706420
Journal: Br J Cancer. 2005 Mar 28;92(6):1137-43.
Title: Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency.
Author: Din, F V N|Stark, L A|Dunlop, M G
PMID: 15770215
Journal: Oncogene. 2005 Jul 21;24(31):4993-9.
Title: Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Author: Zhu, Hongbo|Zhang, Lidong|Dong, Fengqin|Guo, Wei|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Chiao, Paul J|Fang, Bingliang
PMID: 15824729
Journal: Biochem Pharmacol. 2005 Aug 1;70(3):394-406.
Title: HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha.
Author: Place, Robert F|Noonan, Emily J|Giardina, Charles
PMID: 15950952
Journal: FEBS Lett. 2005 Aug 15;579(20):4213-8.
Title: Diclofenac attenuates Wnt/beta-catenin signaling in colon cancer cells by activation of NF-kappaB.
Author: Cho, Munju|Gwak, Jungsug|Park, Seoyoung|Won, Jaejoon|Kim, Dong-Eun|Yea, Sung Su|Cha, In-June|Kim, Tae Kook|Shin, Jae-Gook|Oh, Sangtaek
PMID: 16051228
Journal: J Biol Chem. 2005 Dec 9;280(49):41047-56.
Title: Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression.
Author: Kim, Ki M|Song, Jae J|An, Jee Young|Kwon, Yong Tae|Lee, Yong J
PMID: 16199534
Journal: Int J Cancer. 2006 Jan 15;118(2):326-34.
Title: PKCdelta-mediated regulation of FLIP expression in human colon cancer cells.
Author: Wang, Qingding|Wang, Xiaofu|Zhou, Yuning|Evers, B Mark
PMID: 16052516
Journal: Int J Cancer. 2006 Feb 1;118(3):532-9.
Title: Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells.
Author: Shah, Syed A|Volkov, Yuri|Arfin, Qamrul|Abdel-Latif, Mohamed M|Kelleher, Dermot
PMID: 16106402
Journal: Biochem Pharmacol. 2006 Feb 28;71(5):634-45. Epub 2005 Dec 19.
Title: Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.
Author: Liang, Mei-Chih|Bardhan, Sujata|Pace, Emily A|Rosman, Diana|Beutler, John A|Porco, John A Jr|Gilmore, Thomas D
PMID: 16360644
Journal: J Biol Chem. 2006 May 12;281(19):13724-32. Epub 2006 Mar 21.
Title: Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells.
Author: Matos, Paulo|Jordan, Peter
PMID: 16551621
Journal: Exp Cell Res. 2006 Aug 1;312(13):2433-42. Epub 2006 Apr 25.
Title: Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines.
Author: Nakagawa, Yoshihito|Akao, Yukihiro
PMID: 16733051
Journal: Nutr Cancer. 2006;54(1):69-78.
Title: Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes.
Author: Lu, Haitian|Li, Jingxia|Zhang, Dongyun|Stoner, Gary D|Huang, Chuanshu
PMID: 16800774
Journal: Cancer Gene Ther. 2006 Dec;13(12):1093-104.
Title: The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene.
Author: Konson, A|Mahajna, J A|Danon, A|Rimon, G|Agbaria, R
PMID: 16841079
Journal: BMC Cancer. 2006 Dec 8;6:281.
Title: Intracellular expression of toll-like receptor 4 in neuroblastoma cells and their unresponsiveness to lipopolysaccharide.
Author: Hassan, Ferdaus|Islam, Shamima|Tumurkhuu, Gantsetseg|Naiki, Yoshikazu|Koide, Naoki|Mori, Isamu|Yoshida, Tomoaki|Yokochi, Takashi
PMID: 17156435
Journal: Carcinogenesis. 2007 May;28(5):968-76. Epub 2006 Nov 28.
Title: Aspirin activates the NF-kappaB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer.
Author: Stark, Lesley A|Reid, Kirsten|Sansom, Owen J|Din, Farhat V|Guichard, Sylvie|Mayer, Iain|Jodrell, Duncan I|Clarke, Alan R|Dunlop, Malcolm G
PMID: 17132819
Journal: Acta Pharmacol Sin. 2007 Jan;28(1):81-8.
Title: Triptolide suppresses IL-1beta-induced chemokine and stromelysin-1 gene expression in human colonic subepithelial myofibroblasts.
Author: Tao, Qing-Song|Ren, Jian-An|Li, Jie-Shou
PMID: 17184586
Journal: Scand J Gastroenterol. 2007 Mar;42(3):345-50.
Title: Association of NFKBIA polymorphism with colorectal cancer risk and prognosis in Swedish and Chinese populations.
Author: Gao, Jingfang|Pfeifer, Daniella|He, Lu-Jun|Qiao, Fang|Zhang, Zhiyong|Arbman, Gunnar|Wang, Zhen-Lei|Jia, Cun-Rong|Carstensen, John|Sun, Xiao-Feng
PMID: 17354114
Journal: Mol Immunol. 2007 Jul;44(15):3625-32. Epub 2007 May 22.
Title: Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Steinhilber, Dieter|Stein, Jurgen|Schroder, Oliver
PMID: 17521736
Journal: Zhong Yao Cai. 2007 Mar;30(3):310-3.
Title: [Inhibitory effects of cordyceps extract on growth of colon cancer cells].
Author: Huang, Hao|Wang, Hang|Luo, Rong-cheng
PMID: 17634040
Journal: Cancer Res. 2007 Aug 1;67(15):7266-74.
Title: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.
Author: Rengifo-Cam, William|Umar, Shahid|Sarkar, Shubhashish|Singh, Pomila
PMID: 17671195
Journal: Cancer Res. 2007 Aug 1;67(15):7368-77.
Title: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.
Author: Lluis, Josep M|Buricchi, Francesca|Chiarugi, Paola|Morales, Albert|Fernandez-Checa, Jose C
PMID: 17671207
Journal: Histol Histopathol. 2007 Dec;22(12):1387-98.
Title: NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases.
Author: Sun, X-F|Zhang, H
PMID: 17701919
Journal: Cell Oncol. 2007;29(6):477-82.
Title: EGF-R is expressed and AP-1 and NF-kappaB are activated in stromal myofibroblasts surrounding colon adenocarcinomas paralleling expression of COX-2 and VEGF.
Author: Konstantinopoulos, Panagiotis A|Vandoros, Gerasimos P|Karamouzis, Michalis V|Gkermpesi, Maria|Sotiropoulou-Bonikou, Georgia|Papavassiliou, Athanasios G
PMID: 18032824
Journal: Oncogene. 2008 Apr 17;27(18):2648-55. Epub 2007 Dec 3.
Title: The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.
Author: Loveridge, C J|MacDonald, A D H|Thoms, H C|Dunlop, M G|Stark, L A
PMID: 18059344
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.
Title: Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
Author: Lee, Jenq-Chang|Won, Shen-Jeu|Chao, Chien-Lin|Wu, Feng-Ling|Liu, Hsiao-Sheng|Ling, Pin|Lin, Chun-Nan|Su, Chun-Li
PMID: 18485277
Journal: J Steroid Biochem Mol Biol. 2008 Jul;111(1-2):37-40.
Title: Lithocholic acid down-regulation of NF-kappaB activity through vitamin D receptor in colonic cancer cells.
Author: Sun, Jun|Mustafi, Reba|Cerda, Sonia|Chumsangsri, Anusara|Xia, Yinglin Rick|Li, Yan Chun|Bissonnette, Marc
PMID: 18515093
Journal: J Proteome Res. 2008 Aug;7(8):3507-15.
Title: Evaluation of hepatic-metastasis risk of colorectal cancer upon the protein signature of PI3K/AKT pathway.
Author: Kang, Bin|Hao, Chunyi|Wang, Hongyi|Zhang, Jun|Xing, Rui|Shao, Jianmin|Li, Wenmei|Xu, Ningzhi|Lu, Youyong|Liu, Siqi
PMID: 18570457
Journal: Oncol Rep. 2008 Jul;20(1):41-7.
Title: Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kappaB in HCT116 colon cancer cells.
Author: Lee, Hye Ran|Cheong, Hee-Jeong|Kim, Sook-Ja|Lee, Nam-Su|Park, Hee-Sook|Won, Jong-Ho
PMID: 18575716
Journal: Inflamm Res. 2008 Oct;57(10):472-8.
Title: The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.
Author: Navarro-Peran, E|Cabezas-Herrera, J|Sanchez-Del-Campo, L|Garcia-Canovas, F|Rodriguez-Lopez, J N
PMID: 18830563
Journal: Acta Pol Pharm. 2008 Nov-Dec;65(6):697-702.
Title: Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells.
Author: Kapral, Malgorzata|Parfiniewicz, Beata|Strzalka-Mrozik, Barbara|Zachacz, Agnieszka|Weglarz, Ludmila
PMID: 19172851
Journal: Mol Carcinog. 2009 Mar;48(3):260-270.
Title: Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells.
Author: Yun, Jung-Mi|Afaq, Farrukh|Khan, Naghma|Mukhtar, Hasan
PMID: 18729103
Journal: Pathol Oncol Res. 2009 Mar;15(1):31-6.
Title: Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer.
Author: Qiao, Liang|Wang, Yan|Pang, Roberta|Wang, Jide|Dai, Yun|Ma, Juan|Gu, Qing|Li, Zesong|Zhang, Yusheng|Zou, Bing|Lan, H Y|Wong, Benjamin C Y
PMID: 18752053
Journal: Exp Cell Res. 2009 Feb 1;315(3):432-50.
Title: Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.
Author: Shant, Jasleen|Cheng, Kunrong|Marasa, Bernard S|Wang, Jian-Ying|Raufman, Jean-Pierre
PMID: 19056378
Journal: Chem Biol Interact. 2009 May 15;179(2-3):202-11.
Title: Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling.
Author: Prawan, Auemduan|Saw, Constance Lay Lay|Khor, Tin Oo|Keum, Young-Sam|Yu, Siwang|Hu, Longqin|Kong, Ah-Ng
PMID: 19159619
Journal: IUBMB Life. 2009 Jun;61(6):685-92.
Title: Tax1 enhances cancer cell proliferation via Ras-Raf-MEK-ERK signaling pathway.
Author: Song, Chunjiao|Wang, Weimin|Li, Meng|Liu, Yanxin|Zheng, Dexian
PMID: 19472191
Journal: Eur J Pharmacol. 2009 Sep 15;618(1-3):91-7.
Title: An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation.
Author: Joo, Kanghyun|Lee, Youna|Choi, Deakyu|Han, Jeongoh|Hong, Sungchae|Kim, Young Mi|Jung, Yunjin
PMID: 19616541
Journal: J Surg Oncol. 2009 Dec 15;100(8):725-31.
Title: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway.
Author: Ikebe, Mio|Kitaura, Yoshiki|Nakamura, Masafumi|Tanaka, Haruo|Yamasaki, Akio|Nagai, Shuntaro|Wada, Junji|Yanai, Kosuke|Koga, Kenichiro|Sato, Norihiro|Kubo, Makoto|Tanaka, Masao|Onishi, Hideya|Katano, Mitsuo
PMID: 19722233
Journal: Mol Carcinog. 2010 Feb;49(2):121-9.
Title: Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma.
Author: Lauscher, Johannes C|Grone, Jorn|Dullat, Sonja|Hotz, Birgit|Ritz, Jorg-P|Steinhoff, Ulrich|Buhr, Heinz-J|Visekruna, Alexander
PMID: 20027638
Journal: Food Chem Toxicol. 2010 Mar;48(3):903-9.
Title: Characterization of a profile of the anthocyanins isolated from Vitis coignetiae Pulliat and their anti-invasive activity on HT-29 human colon cancer cells.
Author: Yun, Jeong Won|Lee, Won Sup|Kim, Min Jeong|Lu, Jing Nan|Kang, Myung Hee|Kim, Hoon Gu|Kim, Dong Chul|Choi, Eun Ju|Choi, Jin Young|Kim, Hae Gyeong|Lee, Yun-Kyoung|Ryu, Chung Ho|Kim, Gonsup|Choi, Yung Hyun|Park, Ock Jin|Shin, Sung Chul
PMID: 20060025
Journal: Inflamm Bowel Dis. 2010 Sep;16(9):1514-25.
Title: Bifidobacterium lactis inhibits NF-kappaB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice.
Author: Kim, Seung Won|Kim, Hee Man|Yang, Kyoung Min|Kim, Sun-Ah|Kim, Sung-Kyu|An, Min Ji|Park, Jae Jun|Lee, Sang Kil|Kim, Tae Il|Kim, Won Ho|Cheon, Jae Hee
PMID: 20310012
Journal: Pharmacol Rep. 2010 Jan-Feb;62(1):150-63.
Title: Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Author: Chen, Nian-Hong|Liu, Jian-Wen|Zhong, Jian-Jiang
PMID: 20360625
Journal: Carcinogenesis. 2010 Oct;31(10):1822-32.
Title: An apple oligogalactan prevents against inflammation and carcinogenesis by targeting LPS/TLR4/NF-kappaB pathway in a mouse model of colitis-associated colon cancer.
Author: Liu, Li|Li, Yu H|Niu, Yin B|Sun, Yang|Guo, Zhen J|Li, Qian|Li, Chen|Feng, Juan|Cao, Shou S|Mei, Qi B
PMID: 20400476
Journal: J Biol Chem. 2010 Jun 18;285(25):19162-72.
Title: Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin.
Author: Jani, Tanvi S|DeVecchio, Jennifer|Mazumdar, Tapati|Agyeman, Akwasi|Houghton, Janet A
PMID: 20424169
Journal: Mol Cancer Res. 2010 May;8(5):751-61.
Title: Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products.
Author: Harikumar, Kuzhuvelil B|Sung, Bokyung|Tharakan, Sheeja T|Pandey, Manoj K|Joy, Beena|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B
PMID: 20460401
Journal: J Cell Physiol. 2010 Oct;225(1):266-75.
Title: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.
Author: Yang, Zhengfeng|Li, Chenghai|Wang, Xiu|Zhai, Chunyan|Yi, Zhengfang|Wang, Lei|Liu, Bisheng|Du, Bing|Wu, Huihui|Guo, Xizhi|Liu, Mingyao|Li, Dali|Luo, Jian
PMID: 20509140
Journal: Folia Microbiol (Praha). 2010 Nov;55(6):657-61.
Title: Quantitative evaluation of transcriptional activation of NF-kappaB p65 and p50 subunits and IkappaBalpha encoding genes in colon cancer cells by Desulfovibrio desulfuricans endotoxin.
Author: Kapral, M|Weglarz, L|Parfiniewicz, B|Lodowska, J|Jaworska-Kik, M
PMID: 21253915
Journal: Mol Med Rep. 2010 Jan-Feb;3(1):69-74.
Title: Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls.
Author: Lewander, Andreas|Arbman, Gunnar|Sun, Xiao F
PMID: 21472202
Journal: Carcinogenesis. 2011 Mar;32(3):343-50.
Title: Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis.
Author: Montrose, David C|Horelik, Nicole A|Madigan, James P|Stoner, Gary D|Wang, Li-Shu|Bruno, Richard S|Park, Hea Jin|Giardina, Charles|Rosenberg, Daniel W
PMID: 21098643
Journal: Front Biosci (Elite Ed). 2011 Jan 1;3:410-20.
Title: Sage components enhance cell death through nuclear factor kappa-B signaling.
Author: Deeb, Sally Joseph|El-Baba, Chirine Omar|Hassan, Saadia Bashir|Larsson, Rolf Lennart|Gali-Muhtasib, Hala Uthman
PMID: 21196321
Journal: Cancer Prev Res (Phila). 2011 Jan;4(1):161-71.
Title: Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}.
Author: Greenspan, Emily J|Madigan, James P|Boardman, Lisa A|Rosenberg, Daniel W
PMID: 21205744
Journal: Phytomedicine. 2011 Jun 15;18(8-9):719-25.
Title: p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells.
Author: Chen, Nian-Hong|Zhong, Jian-Jiang
PMID: 21353507
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 Jul;301(1):G9-19.
Title: Fluoxetine inhibits NF-kappaB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice.
Author: Koh, Seong-Joon|Kim, Jung Mogg|Kim, In-Kyoung|Kim, Nayoung|Jung, Hyun Chae|Song, In Sung|Kim, Joo Sung
PMID: 21436313
Journal: Mol Nutr Food Res. 2011 Apr;55(4):635-43.
Title: Vitamin B6 suppresses serine protease inhibitor 3 expression in the colon of rats and in TNF-alpha-stimulated HT-29 cells.
Author: Yanaka, Noriyuki|Ohata, Tomomi|Toya, Keigo|Kanda, Mayumi|Hirata, Atsuko|Kato, Norihisa
PMID: 21462331
Journal: J Cell Biochem. 2011 Sep;112(9):2490-501.
Title: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma.
Author: Cimen, I|Astarci, E|Banerjee, S
PMID: 21544861
Journal: Carcinogenesis. 2011 Jul;32(7):1069-77.
Title: c-Src dependency of NSAID-induced effects on NF-kappaB-mediated apoptosis in colorectal cancer cells.
Author: Brady, Richard R W|Loveridge, Carolyn J|Dunlop, Malcolm G|Stark, Lesley A
PMID: 21551129
Journal: J Exp Clin Cancer Res. 2011 May 17;30:59.
Title: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity.
Author: Ritchie, Shawn A|Jayasinghe, Dushmanthi|Davies, Gerald F|Ahiahonu, Pearson|Ma, Hong|Goodenowe, Dayan B
PMID: 21586136
Journal: Anticancer Res. 2011 May;31(5):1607-17.
Title: NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells.
Author: Gochman, Einat|Mahajna, Jamal|Reznick, Abraham Z
PMID: 21617217
Journal: Cell Signal. 2011 Sep;23(9):1505-13.
Title: An IkappaBalpha phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-kappaB-independent mechanism.
Author: Min, Kyoung-jin|Lee, Jung Tae|Joe, Eun-hye|Kwon, Taeg Kyu
PMID: 21620964
Journal: Tumour Biol. 2011 Oct;32(5):921-30.
Title: Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620.
Author: Guo, Donglin|Zhou, Hong|Wu, Ying|Zhou, Fang|Xu, Guoying|Wen, Haiping|Zhang, Xianmei
PMID: 21625939
Journal: PLoS One. 2011;6(6):e21726.
Title: NFkappaB1 and NFkappaBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population.
Author: Song, Shunxin|Chen, Dianke|Lu, Jiachun|Liao, Jiawei|Luo, Yanxin|Yang, Zuli|Fu, Xinhui|Fan, Xinjuan|Wei, Yisheng|Yang, Lei|Wang, Lei|Wang, Jianping
PMID: 21738780
Journal: Tumour Biol. 2011 Oct;32(5):1005-12.
Title: Differential expression of TNF-alpha signaling molecules and ERK1 in distal and proximal colonic tumors associated with obesity.
Author: Jain, Swati S|AshokKumar, Manickaraj|Bird, Ranjana P
PMID: 21761118
Journal: Cancer Biol Ther. 2011 Nov 1;12(9):797-807.
Title: C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFkappaB in colon cancer cells and xenograft tumors.
Author: Chen, Chun|Liu, Yang|Chen, Yuanzhong|Xu, Jianhua
PMID: 21900746
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Sep;33(9):649-53.
Title: [Role of NF-kappaB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells].
Author: Guo, Dong-lin|Zhou, Hong|Wu, Ying|Zhou, Fang|Zhang, Xian-mei|Xu, Guo-ying|Wen, Hai-ping
PMID: 22340043
Journal: J Pathol. 2012 May;227(1):118-29.
Title: Calpain 2-dependent IkappaBalpha degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts.
Author: Fenouille, Nina|Grosso, Sebastien|Yunchao, Su|Mary, Didier|Pontier-Bres, Rodolphe|Imbert, Veronique|Czerucka, Dorota|Caroli-Bosc, Francois-Xavier|Peyron, Jean-Francois|Lagadec, Patricia
PMID: 22069124
Journal: Anticancer Res. 2012 Jan;32(1):73-9.
Title: Mutated in colorectal cancer protein modulates the NFkappaB pathway.
Author: Sigglekow, Nicholas D|Pangon, Laurent|Brummer, Tilman|Molloy, Mark|Hawkins, Nicholas J|Ward, Robyn L|Musgrove, Elizabeth A|Kohonen-Corish, Maija R J
PMID: 22213290
Journal: Oncol Rep. 2012 May;27(5):1527-34.
Title: NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBalpha pathway.
Author: Lin, Gen|Tang, Zhiwei|Ye, Yun-Bin|Chen, Qiang
PMID: 22327383
Journal: Mol Cell. 2012 Mar 30;45(6):731-42.
Title: The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response.
Author: Formentini, Laura|Sanchez-Arago, Maria|Sanchez-Cenizo, Laura|Cuezva, Jose M
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Journal: Carcinogenesis. 2012 Jun;33(6):1158-68.
Title: Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
Author: Wang, Tz-Ping|Hsu, Shu-Han|Feng, Hsin-Chun|Huang, Rwei-Fen S
PMID: 22461522
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
PMID: 22465936
Journal: Cancer Gene Ther. 2012 Oct;19(10):715-22.
Title: Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation.
Author: Pan, J|Fauzee, N J S|Wang, Y-l|Sheng, Y-T|Tang, Y|Wang, J-Q|Wu, W-q|Yan, J-x|Xu, J
PMID: 22918473
Journal: Mol Carcinog. 2013 Mar;52(3):195-206.
Title: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling.
Author: Raina, Komal|Agarwal, Chapla|Agarwal, Rajesh
PMID: 22086675
Journal: Nutr Cancer. 2013;65(1):147-56.
Title: Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1alpha.
Author: Cardeno, Ana|Sanchez-Hidalgo, Marina|Rosillo, M Angeles|Alarcon de la Lastra, Catalina
PMID: 23368925
Journal: J Biol Chem. 2013 Mar 29;288(13):9001-10.
Title: Secreted heat shock protein 90alpha (HSP90alpha) induces nuclear factor-kappaB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion.
Author: Chen, Wei-Shone|Chen, Chia-Chi|Chen, Li-Li|Lee, Chun-Chung|Huang, Tze-Sing
PMID: 23386606
Journal: PLoS One. 2013;8(2):e55710.
Title: The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
Author: Hori, Masato|Miki, Tomoharu|Okamoto, Mayumi|Yazama, Futoshi|Konishi, Hiroaki|Kaneko, Hiroshi|Shimamoto, Fumio|Ota, Takahide|Temme, Achim|Tatsuka, Masaaki
PMID: 23405201
Journal: PLoS One. 2013;8(2):e57218.
Title: Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
Author: Shakibaei, Mehdi|Mobasheri, Ali|Lueders, Cora|Busch, Franziska|Shayan, Paviz|Goel, Ajay
PMID: 23451189
Journal: PLoS One. 2013;8(3):e58733.
Title: Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.
Author: Meunier, Charles|Van Der Kraak, Lauren|Turbide, Claire|Groulx, Normand|Labouba, Ingrid|Cingolani, Pablo|Blanchette, Mathieu|Yeretssian, Garabet|Mes-Masson, Anne-Marie|Saleh, Maya|Beauchemin, Nicole|Gros, Philippe
PMID: 23516545
Journal: Mol Cancer Res. 2013 Jul;11(7):724-35.
Title: Epigenetic control of NF-kappaB-dependent FAS gene transcription during progression of myelodysplastic syndromes.
Author: Ettou, Sandrine|Humbrecht, Catherine|Benet, Blandine|Billot, Katy|d'Allard, Diane|Mariot, Virginie|Goodhardt, Michele|Kosmider, Olivier|Mayeux, Patrick|Solary, Eric|Fontenay, Michaela
PMID: 23604035
Journal: Clin Cancer Res. 2013 Aug 15;19(16):4465-76.
Title: Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment.
Author: Gupta, Subash C|Prasad, Sahdeo|Sethumadhavan, Dhanya R|Nair, Mangalam S|Mo, Yin-Yuan|Aggarwal, Bharat B
PMID: 23766363
Journal: Carcinogenesis. 2013 Oct;34(10):2350-60.
Title: A mechanistic study of the proapoptotic effect of tolfenamic acid: involvement of NF-kappaB activation.
Author: Jeong, Jin Boo|Yang, Xuyu|Clark, Ruth|Choi, Jieun|Baek, Seung Joon|Lee, Seong-Ho
PMID: 23784084
Journal: J Sci Food Agric. 2013 Dec;93(15):3820-5.
Title: Anti-inflammatory and immunomodulatory activities of stevioside and steviol on colonic epithelial cells.
Author: Boonkaewwan, Chaiwat|Burodom, Anyanee
PMID: 23794454
Journal: Arch Biochem Biophys. 2013 Sep 15;537(2):168-75.
Title: Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells.
Author: Jeong, Jin Boo|Choi, Jieun|Baek, Seung Joon|Lee, Seong-Ho
PMID: 23896517
Journal: Med Oncol. 2013 Dec;30(4):693.
Title: Gender-specific association of NFKBIA promoter polymorphisms with the risk of sporadic colorectal cancer.
Author: Tan, Shing Cheng|Suzairi, Mohd Shafi'i Mohd|Aizat, Abdul Aziz Ahmad|Aminudin, Mustapha Mohd|Nurfatimah, Mohd Shahpudin Siti|Bhavaraju, Venkata Murali Krishna|Biswal, Biswa Mohan|Ankathil, Ravindran
PMID: 23996241
Journal: Cell Commun Signal. 2013 Oct 1;11:73.
Title: Sulindac activates NF-kappaB signaling in colon cancer cells.
Author: Mladenova, Dessislava|Pangon, Laurent|Currey, Nicola|Ng, Irvin|Musgrove, Elizabeth A|Grey, Shane T|Kohonen-Corish, Maija R J
PMID: 24083678
Journal: Discov Med. 2013 Oct;16(88):137-47.
Title: Epigenetic silencing of CXCL14 induced colorectal cancer migration and invasion.
Author: Cao, Baoping|Yang, Yunsheng|Pan, Yuanming|Jia, Yan|Brock, Malcolm V|Herman, James G|Guo, Mingzhou
PMID: 24099668
Journal: Cell Physiol Biochem. 2013;32(6):1587-99.
Title: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-kappaB pathway.
Author: Xiao, Ming|Tang, Yi|Wang, Ya-Lan|Yang, Lian|Li, Xian|Kuang, Jing|Song, Guang-Lin
PMID: 24335275
Journal: PLoS One. 2013 Dec 18;8(12):e83859.
Title: Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancer.
Author: Burghel, George J|Lin, Wei-Yu|Whitehouse, Helen|Brock, Ian|Hammond, David|Bury, Jonathan|Stephenson, Yvonne|George, Rina|Cox, Angela
PMID: 24367615
Journal: Mol Carcinog. 2014 Feb;53(2):145-58.
Title: Oroxylin A prevents inflammation-related tumor through down-regulation of inflammatory gene expression by inhibiting NF-kappaB signaling.
Author: Yao, Jing|Hu, Rong|Sun, Jie|Lin, Biqi|Zhao, Li|Sha, Yunying|Zhu, Binbin|You, Qi-Dong|Yan, Tianhua|Guo, Qing-Long
PMID: 22949302
Journal: J Gastroenterol Hepatol. 2014 Mar;29(3):502-10.
Title: Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer.
Author: Koh, Seong-Joon|Kim, Jung Mogg|Kim, In-Kyoung|Ko, Su Hyuk|Kim, Joo Sung
PMID: 24716225
Journal: Biomol Ther (Seoul). 2015 Jan;23(1):39-44.
Title: Tolfenamic Acid Suppresses Inflammatory Stimuli-Mediated Activation of NF-kappaB Signaling.
Author: Shao, Hong Jun|Lou, Zhiyuan|Jeong, Jin Boo|Kim, Kui Jin|Lee, Jihye|Lee, Seong-Ho
PMID: 25593642
Journal: Oncotarget. 2015 Mar 20;6(8):6160-78.
Title: Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFkappaB signaling.
Author: Zhang, Yonggang|Liu, Shu|Wang, Hong|Yang, Wensheng|Li, Fang|Yang, Fan|Yu, Daohai|Ramsey, Frederick V|Tuszyski, George P|Hu, Wenhui
PMID: 25704885
Journal: Oncol Rep. 2015 Jun;33(6):2940-6.
Title: Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-kappaB activity in SW620 human colon cancer cells.
Author: Lee, Won Sup|Yun, Jeong Won|Nagappan, Arulkumar|Park, Hyeon Soo|Lu, Jing Nan|Kim, Hye Jung|Chang, Seong-Hwan|Kim, Dong Chul|Lee, Jeong-Hee|Jung, Jin-Myung|Hong, Soon Chan|Ha, Woo Song|Kim, Gonsup
PMID: 25845556
Journal: Oncotarget. 2015 Aug 21;6(24):20288-301.
Title: Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IkappaB.
Author: Muller-Edenborn, Kamila|Leger, Karolin|Glaus Garzon, Jesus F|Oertli, Carole|Mirsaidi, Ali|Richards, Peter J|Rehrauer, Hubert|Spielmann, Patrick|Hoogewijs, David|Borsig, Lubor|Hottiger, Michael O|Wenger, Roland H
PMID: 25978030
Journal: Tumour Biol. 2015 Dec;36(12):9499-510.
Title: Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity.
Author: Wang, Ziyuan|Zhang, Long|Ni, Zhenhua|Sun, Jian|Gao, Hong|Cheng, Zhuoan|Xu, Jianhua|Yin, Peihao
PMID: 26124005
Journal: Oncol Lett. 2015 May;9(5):2135-2142.
Title: Parthenolide induces apoptosis in colitis-associated colon cancer, inhibiting NF-kappaB signaling.
Author: Kim, Se Lim|Liu, Yu Chuan|Seo, Seung Young|Kim, Seong Hun|Kim, In Hee|Lee, Seung Ok|Lee, Soo Teik|Kim, Dae-Ghon|Kim, Sang Wook
PMID: 26137027
Journal: Growth Horm IGF Res. 2015 Oct;25(5):253-61.
Title: Crosstalk between the TNF and IGF pathways enhances NF-kappaB activation and signaling in cancer cells.
Author: Li, Shun|Pinard, Maxime|Wang, Yunling|Yang, Long|Lin, Rongtuan|Hiscott, John|Su, Bing|Brodt, Pnina
PMID: 26239406
Journal: Biochem Pharmacol. 2015 Nov 1;98(1):51-68.
Title: Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.
Author: Buhrmann, Constanze|Shayan, Parviz|Kraehe, Patricia|Popper, Bastian|Goel, Ajay|Shakibaei, Mehdi
PMID: 26310874
Journal: Int J Oncol. 2015 Dec;47(6):2276-85.
Title: Chemosensitization by diverging modulation by short-term and long-term TNF-alpha action on ABCB1 expression and NF-kappaB signaling in colon cancer.
Author: Walther, Wolfgang|Kobelt, Dennis|Bauer, Lisa|Aumann, Jutta|Stein, Ulrike
PMID: 26463665
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2015 Nov;35(11):1356-60.
Title: [Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes].
Author: Chen, Jin-tuan|Ke, Xiao|Zhang, Xin|Fang, Wen-yi|Yang, Chun-bo|Peng, Jun|Chen, You-qin|Speerra, Thomas J
PMID: 26775485
Journal: Int J Oncol. 2016 Aug;49(2):487-98.
Title: Combination treatment with flavonoid morin and telomerase inhibitor MST312 reduces cancer stem cell traits by targeting STAT3 and telomerase.
Author: Chung, Seyung S|Oliva, Bryant|Dwabe, Sami|Vadgama, Jaydutt V
PMID: 27279256
Journal: Cancer Lett. 2016 Sep 28;380(1):87-97.
Title: Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis.
Author: Lu, Yun-Xin|Ju, Huai-Qiang|Wang, Feng|Chen, Le-Zong|Wu, Qi-Nian|Sheng, Hui|Mo, Hai-Yu|Pan, Zhi-Zhong|Xie, Dan|Kang, Tie-Bang|Chen, Gong|Yun, Jing-Ping|Zeng, Zhao-Lei|Xu, Rui-Hua
PMID: 27322737
Journal: Protein Cell. 2016 Aug;7(8):571-85.
Title: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author: Shan, Jianzhen|Xuan, Yanyan|Zhang, Qi|Zhu, Chunpeng|Liu, Zhen|Zhang, Suzhan
PMID: 27472952
Journal: Int J Oncol. 2016 Nov;49(5):1953-1962.
Title: Knockdown of RPL9 expression inhibits colorectal carcinoma growth via the inactivation of Id-1/NF-kappaB signaling axis.
Author: Baik, In Hye|Jo, Guk-Heui|Seo, Daekwan|Ko, Min Ji|Cho, Chi Heum|Lee, Min Goo|Lee, Yun-Han
PMID: 27633352
Journal: PLoS One. 2016 Sep 29;11(9):e0163209.
Title: Novel Synthetic Oxazines Target NF-kappaB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo.
Author: Nirvanappa, Anilkumar C|Mohan, Chakrabhavi Dhananjaya|Rangappa, Shobith|Ananda, Hanumappa|Sukhorukov, Alexey Yu|Shanmugam, Muthu K|Sundaram, Mahalingam S|Nayaka, Siddaiah Chandra|Girish, Kesturu S|Chinnathambi, Arunachalam|Zayed, M E|Alharbi, Sulaiman Ali
PMID: 27685808
Journal: BMC Cancer. 2016 Oct 12;16(1):791.
Title: Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
Author: Ding, Chenbo|Li, Longmei|Yang, Taoyu|Fan, Xiaobo|Wu, Guoqiu
PMID: 27729020
Journal: Food Funct. 2016 Dec 7;7(12):4797-4803.
Title: The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-kappaB signaling pathway.
Author: Hsieh, Shu-Chen|Hsieh, Wang-Ju|Chiang, An-Na|Su, Nan-Wei|Yeh, Yu-Te|Liao, Yi-Chun
PMID: 27869910
Journal: J Pineal Res. 2017 Mar;62(2).
Title: Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-kappaB/iNOS signaling pathways.
Author: Gao, Yue|Xiao, Xiangsheng|Zhang, Changlin|Yu, Wendan|Guo, Wei|Zhang, Zhifeng|Li, Zhenglin|Feng, Xu|Hao, Jiaojiao|Zhang, Kefang|Xiao, Bingyi|Chen, Miao|Huang, Wenlin|Xiong, Shunbin|Wu, Xiaojun|Deng, Wuguo
PMID: 27865009
Journal: PLoS One. 2017 Jan 26;12(1):e0170595.
Title: Knockdown of NIK and IKKbeta-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-kappaBeta Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.
Author: Qin, Mengbin|Zhang, Jinxiu|Xu, Chunyan|Peng, Peng|Tan, Lin|Liu, Shiquan|Huang, Jiean
PMID: 28125661
Journal: Mol Cancer. 2017 May 5;16(1):87.
Title: Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer.
Author: Liu, Qiao|Chen, Zhuojia|Jiang, Guanmin|Zhou, Yan|Yang, Xiangling|Huang, Hongbin|Liu, Huanliang|Du, Jun|Wang, Hongsheng
PMID: 28476123
Journal: Pharmazie. 2017 Aug 1;72(8):475-481.
Title: microRNA-335 inhibits colorectal cancer HCT116 cells growth and epithelial-mesenchymal transition (EMT) process by targeting Twist1.
Author: Wang, Jingyuan|Wang, Xuemei|Liu, Fengjun|Fu, Yuguang
PMID: 29441907
Journal: Int J Cancer. 2018 May 15;142(10):2068-2079.
Title: DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-kappaB pathway in colorectal cancer.
Author: Liu, Weiying|Wang, Shixing|Sun, Qi|Yang, Zhen|Liu, Min|Tang, Hua
PMID: 29277893
Journal: Int J Mol Med. 2018 Mar;41(3):1305-1314.
Title: Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-kappaB signaling pathway.
Author: Luan, Yunpeng|Li, Yanmei|Zhu, Lina|Zheng, Shuangqing|Mao, Dechang|Chen, Zhuxue|Cao, Yong
PMID: 29286074
Journal: Mol Cancer. 2018 Jan 30;17(1):16.
Title: Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.
Author: Weng, Wenhao|Liu, Na|Toiyama, Yuji|Kusunoki, Masato|Nagasaka, Takeshi|Fujiwara, Toshiyoshi|Wei, Qing|Qin, Huanlong|Lin, Haifan|Ma, Yanlei|Goel, Ajay
PMID: 29382334
Journal: Nutrients. 2018 Feb 12;10(2). pii: nu10020202.
Title: Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
Author: Chung, Kyung-Sook|Cheon, Se-Yun|Roh, Seong-Soo|Lee, Minho|An, Hyo-Jin
PMID: 29439531
Journal: Cell Death Dis. 2018 Feb 14;9(2):248.
Title: Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization.
Author: Li, Mengyang|Lai, Xiaofeng|Zhao, Ying|Zhang, Yuan|Li, Minghui|Li, Danxiu|Kong, Jing|Zhang, Yong|Jing, Pengyu|Li, Huichen|Qin, Hongyan|Shen, Liangliang|Yao, Libo|Li, Jipeng|Dou, Kefeng|Zhang, Jian
PMID: 29445150
Journal: Cancer Sci. 2018 Apr;109(4):1220-1229.
Title: Antimalarial drug mefloquine inhibits nuclear factor kappa B signaling and induces apoptosis in colorectal cancer cells.
Author: Xu, Xin|Wang, Jun|Han, Kunkun|Li, Shaoyan|Xu, Feng|Yang, Yili
PMID: 29453896
Journal: Cell Death Dis. 2018 Feb 22;9(3):315.
Title: Co-inhibition of BET proteins and NF-kappaB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions.
Author: Wu, Tingyu|Wang, Guanghui|Chen, Wei|Zhu, Zhehui|Liu, Yun|Huang, Zhenyu|Huang, Yuji|Du, Peng|Yang, Yili|Liu, Chen-Ying|Cui, Long
PMID: 29472532
Journal: Int Immunopharmacol. 2018 Apr;57:82-90.
Title: Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-kappaB and MAPK signalling pathways.
Author: Gao, Zhenfang|Yu, Cuicui|Liang, Haiyue|Wang, Xuekai|Liu, Yue|Li, Xin|Ji, Kai|Xu, Hui|Yang, Mingyan|Liu, Ke|Qi, Dong|Fan, Huaying
PMID: 29475099
Journal: Gastroenterol Hepatol Bed Bench. 2018 Winter;11(1):48-53.
Title: Single nucleotide polymorphism rs696 in miR449a binding site of NFKBIA gene is correlated with risk of colorectal cancer.
Author: Simonian, Miganoosh|Mosallayi, Meysam|Miraghajani, Maryam|Feizi, Awat|Khosravi, Sharifeh|Salehi, Ahmad Reza|Mortazavi, Deniz|Saberi, Farideh|Salehi, Rasoul
PMID: 29564065
Journal: Chem Biol Interact. 2018 Aug 1;291:16-28.
Title: Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer.
Author: Sharma, Sharada H|Rajamanickam, Vinothkumar|Nagarajan, Sangeetha
PMID: 29879413
Journal: Cancer Biol Ther. 2018 Oct 25:1-11.
Title: Metformin inhibited colitis and colitis-associated cancer (CAC) through protecting mitochondrial structures of colorectal epithelial cells in mice.
Author: Wang, Shu-Qing|Cui, Shu-Xiang|Qu, Xian-Jun
PMID: 30359174
Journal: Biomed Res Int. 2018 Sep 27;2018:2548378.
Title: alpha-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-kappaB Signaling in Colon Cancer Cells.
Author: Sun, Dongdong|Shen, Weixing|Zhang, Feng|Fan, Huisen|Tan, Jiani|Li, Liu|Xu, Changliang|Zhang, Haibin|Yang, Ye|Cheng, Haibo
PMID: 30363706
Journal: J Gastroenterol Hepatol. 2018 Oct 30.
Title: Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling.
Author: Kim, Young Hoon|Kim, Jee Hyun|Kim, Byeong Gwan|Lee, Kook Lae|Kim, Ji Won|Koh, Seong-Joon
PMID: 30378164