Primary Site >> Colorectal Cancer

Gene >> NFKB1

Journal: Biochem Pharmacol. 1994 Jan 13;47(1):145-9.
Title: The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines.
Author: Bours, V|Dejardin, E|Goujon-Letawe, F|Merville, M P|Castronovo, V
PMID: 8311838
Journal: Oncogene. 1998 Mar 5;16(9):1187-95.
Title: Nuclear factor - kappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug.
Author: Hellin, A C|Calmant, P|Gielen, J|Bours, V|Merville, M P
PMID: 9528861
Journal: Clin Cancer Res. 1998 Oct;4(10):2337-47.
Title: Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy.
Author: Bukowski, R M|Rayman, P|Uzzo, R|Bloom, T|Sandstrom, K|Peereboom, D|Olencki, T|Budd, G T|McLain, D|Elson, P|Novick, A|Finke, J H
PMID: 9796963
Journal: J Biol Chem. 2000 Sep 8;275(36):28173-9.
Title: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.
Author: Paik, J H|Ju, J H|Lee, J Y|Boudreau, M D|Hwang, D H
PMID: 10866999
Journal: Mol Carcinog. 2000 Sep;29(1):25-36.
Title: IkappaBbeta-related proteins in normal and transformed colonic epithelial cells.
Author: Inan, M S|Place, R|Tolmacheva, V|Wang, Q S|Hubbard, A K|Rosenberg, D W|Giardina, C
PMID: 11020244
Journal: Biofactors. 2000;13(1-4):153-8.
Title: Recent studies on the biofunctions and biotransformations of curcumin.
Author: Lin, J K|Pan, M H|Lin-Shiau, S Y
PMID: 11237176
Journal: Proc Natl Sci Counc Repub China B. 2001 Apr;25(2):59-66.
Title: Mechanisms of cancer chemoprevention by curcumin.
Author: Lin, J K|Lin-Shiau, S Y
PMID: 11370761
Journal: Exp Cell Res. 2001 Jul 1;267(1):73-80.
Title: Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells.
Author: Ikawa, H|Kameda, H|Kamitani, H|Baek, S J|Nixon, J B|Hsi, L C|Eling, T E
PMID: 11412039
Journal: Cytokine. 2001 Jul 21;15(2):108-12.
Title: TNF and CD95 promote IL-8 gene transactivation via independent elements in colon carcinoma cells.
Author: Verhagen, A M|Pakusch, M|Silke, J|Vaux, D L
PMID: 11500086
Journal: Cancer Chemother Pharmacol. 2002 Jan;49(1):27-34.
Title: Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells.
Author: Feinman, Rena|Clarke, Kevin O|Harrison, Lawrence E
PMID: 11855750
Journal: Ann Surg. 2002 Apr;235(4):507-11.
Title: Increased adhesion molecule expression in serosal fibroblasts isolated from patients with inflammatory bowel disease is secondary to inflammation.
Author: Brannigan, Ann E|Watson, R William G|Beddy, David|Hurley, Hilary|Fitzpatrick, John M|O'Connell, P Ronan
PMID: 11923606
Journal: Gastroenterology. 2002 Oct;123(4):1163-78.
Title: PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
Author: Kim, Sunghoon|Domon-Dell, Claire|Wang, Qingding|Chung, Dai H|Di Cristofano, Antonio|Pandolfi, Pier Paolo|Freund, Jean-Noel|Evers, B Mark
PMID: 12360479
Journal: Cancer Res. 2002 Dec 1;62(23):6857-63.
Title: Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts.
Author: Huang, Chuanshu|Huang, Yi|Li, Jingxia|Hu, Wenwei|Aziz, Robeena|Tang, Moon-shong|Sun, Nanjun|Cassady, John|Stoner, Gary D
PMID: 12460899
Journal: Cancer Res. 2002 Dec 1;62(23):6870-8.
Title: Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis.
Author: Scaife, Courtney L|Kuang, Jinqiu|Wills, Jason C|Trowbridge, D Brad|Gray, Phil|Manning, Bernadette M|Eichwald, Ernst J|Daynes, Raymond A|Kuwada, Scott K
PMID: 12460901
Journal: Ann N Y Acad Sci. 2002 Nov;973:414-8.
Title: Thalidomide suppresses the interleukin 1beta-induced NFkappaB signaling pathway in colon cancer cells.
Author: Jin, Soo Hyun|Kim, Tae Il|Han, Dong Soo|Shin, Sung Kwan|Kim, Won Ho
PMID: 12485902
Journal: Carcinogenesis. 2002 Dec;23(12):2063-80.
Title: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author: Crowley-Weber, Cara L|Payne, Claire M|Gleason-Guzman, Mary|Watts, George S|Futscher, Bernard|Waltmire, Caroline N|Crowley, Cheray|Dvorakova, Katerina|Bernstein, Carol|Craven, Mary|Garewal, Harinder|Bernstein, Harris
PMID: 12507930
Journal: J Nutr Biochem. 2003 Apr;14(4):227-31.
Title: Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver(1,2).
Author: Zeng, Huawei|Davis, Cindy D|Finley, John W
PMID: 12770647
Journal: Cancer Res. 2003 Jul 1;63(13):3560-6.
Title: Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer.
Author: Landi, Stefano|Moreno, Victor|Gioia-Patricola, Lydie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 12839942
Journal: Cancer Res. 2003 Jul 1;63(13):3632-6.
Title: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.
Author: Liu, Wenbiao|Reinmuth, Niels|Stoeltzing, Oliver|Parikh, Alexander A|Tellez, Carmen|Williams, Simon|Jung, Young D|Fan, Fan|Takeda, Akihiko|Akagi, Morihisa|Bar-Eli, Menashe|Gallick, Gary E|Ellis, Lee M
PMID: 12839952
Journal: Cell Death Differ. 2003 Sep;10(9):1078-89.
Title: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Author: Hermisson, M|Weller, M
PMID: 12934082
Journal: Aliment Pharmacol Ther. 2003 Sep;18 Suppl 2:10-4.
Title: Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease.
Author: Allgayer, H
PMID: 12950415
Journal: J Biol Chem. 2003 Dec 12;278(50):50442-8.
Title: Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling.
Author: Matos, Paulo|Collard, John G|Jordan, Peter
PMID: 14506233
Journal: Br J Cancer. 2003 Oct 6;89(7):1358-65.
Title: Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells.
Author: Smartt, H J M|Elder, D J E|Hicks, D J|Williams, N A|Paraskeva, C
PMID: 14520472
Journal: Cancer Res. 2003 Dec 1;63(23):8132-7.
Title: Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
Author: Ikenoue, Tsuneo|Hikiba, Yohko|Kanai, Fumihiko|Tanaka, Yasuo|Imamura, Jun|Imamura, Takaaki|Ohta, Miki|Ijichi, Hideaki|Tateishi, Keisuke|Kawakami, Takayuki|Aragaki, Jun|Matsumura, Masayuki|Kawabe, Takao|Omata, Masao
PMID: 14678966
Journal: Korean J Gastroenterol. 2004 Mar;43(3):176-85.
Title: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8].
Author: Lee, Dong Ki|Park, Sun Young|Baik, Soon Koo|Kwon, Sang Ok|Chung, Jun Mo|Oh, Eok-Soo|Kim, Hyun Soo
PMID: 15034288
Journal: Mol Ther. 2004 May;9(5):666-73.
Title: Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Author: Zhu, Hongbo|Zhang, Lidong|Huang, Xuefeng|Davis, John J|Jacob, Dietmar A|Teraishi, Fuminori|Chiao, Paul|Fang, Bingliang
PMID: 15120327
Journal: Am J Physiol Lung Cell Mol Physiol. 2004 Nov;287(5):L981-91.
Title: Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer.
Author: Martey, Christine A|Pollock, Stephen J|Turner, Chantal K|O'Reilly, Katherine M A|Baglole, Carolyn J|Phipps, Richard P|Sime, Patricia J
PMID: 15234907
Journal: Carcinogenesis. 2004 Nov;25(11):2183-9. Epub 2004 Jul 15.
Title: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick Charles
PMID: 15256484
Journal: Br J Cancer. 2005 Mar 28;92(6):1137-43.
Title: Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency.
Author: Din, F V N|Stark, L A|Dunlop, M G
PMID: 15770215
Journal: DNA Cell Biol. 2005 Apr;24(4):209-17.
Title: Synergy between deacetylase inhibitors and IL-1beta in activation of the serum amyloid A2 gene promoter.
Author: Blais, Mylene|Desilets, Antoine|Asselin, Claude
PMID: 15812237
Journal: Oncogene. 2005 Jul 21;24(31):4993-9.
Title: Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Author: Zhu, Hongbo|Zhang, Lidong|Dong, Fengqin|Guo, Wei|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Chiao, Paul J|Fang, Bingliang
PMID: 15824729
Journal: Carcinogenesis. 2005 Nov;26(11):1988-98.
Title: Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells.
Author: Parhamifar, Ladan|Jeppsson, Bengt|Sjolander, Anita
PMID: 15975962
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5526-33.
Title: A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.
Author: Mackay, Helen|Hedley, David|Major, Pierre|Townsley, Carol|Mackenzie, Mary|Vincent, Mark|Degendorfer, Pam|Tsao, Ming-Sound|Nicklee, Trudey|Birle, Diana|Wright, John|Siu, Lillian|Moore, Malcolm|Oza, Amit
PMID: 16061869
Journal: Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1295-303.
Title: Nuclear factor kappaB (NFkappaB) and cyclooxygenase-2 (Cox-2) expression in the irradiated colorectum is associated with subsequent histopathological changes.
Author: Yeoh, Ann S J|Bowen, Joanne M|Gibson, Rachel J|Keefe, Dorothy M K
PMID: 16099597
Journal: Biochem Pharmacol. 2005 Oct 15;70(8):1147-57.
Title: Induction of apoptotic cell death by 2'-hydroxycinnamaldehyde is involved with ERK-dependent inactivation of NF-kappaB in TNF-alpha-treated SW620 colon cancer cells.
Author: Lee, Seung Ho|Lee, Chung Woo|Lee, Jae Woong|Choi, Myoung Suk|Son, Dong Ju|Chung, Youn Bok|Lee, Chong Kil|Oh, Ki Wan|Moon, Dong Chul|Kwon, Byoung Mog|Hong, Jin Tae
PMID: 16143316
Journal: Gut. 2006 Feb;55(2):234-42. Epub 2005 Aug 23.
Title: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas.
Author: Volp, K|Brezniceanu, M-L|Bosser, S|Brabletz, T|Kirchner, T|Gottel, D|Joos, S|Zornig, M
PMID: 16118352
Journal: Biochem Pharmacol. 2006 Feb 28;71(5):634-45. Epub 2005 Dec 19.
Title: Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.
Author: Liang, Mei-Chih|Bardhan, Sujata|Pace, Emily A|Rosman, Diana|Beutler, John A|Porco, John A Jr|Gilmore, Thomas D
PMID: 16360644
Journal: J Agric Food Chem. 2006 Feb 8;54(3):980-5.
Title: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
Author: Adams, Lynn S|Seeram, Navindra P|Aggarwal, Bharat B|Takada, Yasunari|Sand, Daniel|Heber, David
PMID: 16448212
Journal: Int J Oncol. 2006 Mar;28(3):695-704.
Title: Inhibition of NF-kappaB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells.
Author: Laos, Sirle|Baeckstrom, Dan|Hansson, Gunnar C
PMID: 16465375
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Anticancer Res. 2006 Mar-Apr;26(2A):1281-8.
Title: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.
Author: Su, Chin-Cheng|Chen, Guang-Wei|Lin, Jaung-Geng|Wu, Lii-Tzu|Chung, Jing-Gung
PMID: 16619535
Journal: Mol Carcinog. 2006 Sep;45(9):685-93.
Title: Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase.
Author: Choi, Woonyoung|Proctor, Lynsey|Xia, Qianghua|Feng, Yumei|Gerner, Eugene W|Chiao, Paul J|Hamilton, Stanley R|Zhang, Wei
PMID: 16637064
Journal: Nutr Cancer. 2006;54(1):69-78.
Title: Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes.
Author: Lu, Haitian|Li, Jingxia|Zhang, Dongyun|Stoner, Gary D|Huang, Chuanshu
PMID: 16800774
Journal: J Cell Physiol. 2006 Dec;209(3):950-8.
Title: Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells.
Author: Broom, Oliver Jay|Massoumi, Ramin|Sjolander, Anita
PMID: 16972245
Journal: Pharmacogenet Genomics. 2006 Nov;16(11):783-8.
Title: No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemia.
Author: Riemann, Kathrin|Becker, Lucie|Struwe, Henrike|Nuckel, Holger|Duhrsen, Ulrich|Alakus, Hakan|Winde, Gunter|Neuhauser, Markus|Rubben, Herbert|Schmitz, Klaus J|Wohlschlaeger, Jeremias|Schmid, Kurt W|Siffert, Winfried
PMID: 17047486
Journal: Gut. 2007 Jan;56(1):73-81. Epub 2006 Jun 15.
Title: Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis.
Author: Han, X|Benight, N|Osuntokun, B|Loesch, K|Frank, S J|Denson, L A
PMID: 16777921
Journal: Mol Carcinog. 2007 May;46(5):402-13.
Title: Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells.
Author: Fukuyama, Ryuichi|Ng, Kwok Peng|Cicek, Muzaffer|Kelleher, Clare|Niculaita, Roxana|Casey, Graham|Sizemore, Nywana
PMID: 17186550
Journal: JPEN J Parenter Enteral Nutr. 2007 Jan-Feb;31(1):18-25.
Title: Prevention of cancer cachexia by pyrrolidine dithiocarbamate (PDTC) in colon 26 tumor-bearing mice.
Author: Nai, Yong-Jun|Jiang, Zhi-Wei|Wang, Zhi-Ming|Li, Ning|Li, Jie-Shou
PMID: 17202436
Journal: Mol Immunol. 2007 Jul;44(15):3625-32. Epub 2007 May 22.
Title: Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Steinhilber, Dieter|Stein, Jurgen|Schroder, Oliver
PMID: 17521736
Journal: Cell Cycle. 2007 Jun 1;6(11):1293-7. Epub 2007 Jun 19.
Title: CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA.
Author: Thoms, Hazel C|Dunlop, Malcolm G|Stark, Lesley A
PMID: 17525529
Journal: Dis Colon Rectum. 2007 Aug;50(8):1230-40.
Title: RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways.
Author: Fuentes, Maren K|Nigavekar, Shraddha S|Arumugam, Thiruvengadam|Logsdon, Craig D|Schmidt, Ann Marie|Park, Juliet C|Huang, Emina H
PMID: 17587138
Journal: J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author: Huerta, Sergio|Heinzerling, John H|Anguiano-Hernandez, Yu-Mei|Huerta-Yepez, Sara|Lin, Jeffrey|Chen, David|Bonavida, Benjamin|Livingston, Edward H
PMID: 17603079
Journal: Int J Oncol. 2007 Aug;31(2):269-75.
Title: Loss of E-cadherin in the vicinity of necrosis in colorectal carcinomas: association with NFkappaB expression.
Author: Simiantonaki, Nektaria|Kurzik-Dumke, Ursula|Karyofylli, Georgia|Jayasinghe, Caren|Kirkpatrick, Charles James
PMID: 17611682
Journal: J Cell Sci. 2007 Aug 1;120(Pt 15):2672-82. Epub 2007 Jul 17.
Title: Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Author: Avvisato, Christopher L|Yang, Xiang|Shah, Salim|Hoxter, Becky|Li, Weiqun|Gaynor, Richard|Pestell, Richard|Tozeren, Aydin|Byers, Stephen W
PMID: 17635998
Journal: Exp Cell Res. 2007 Oct 1;313(16):3446-58. Epub 2007 Jul 13.
Title: 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways.
Author: Richard, Cynthia Lee|Lowthers, Erica Lauren|Blay, Jonathan
PMID: 17707368
Journal: Scand J Gastroenterol. 2007 Nov;42(11):1332-8.
Title: Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations.
Author: Lewander, Andreas|Butchi, Anil Kumar Reddy|Gao, Jingfang|He, Lu-Jun|Lindblom, Annika|Arbman, Gunnar|Carstensen, John|Zhang, Zhi-Yong|Sun, Xiao-Feng
PMID: 17852842
Journal: Toxicol Appl Pharmacol. 2007 Dec 1;225(2):198-205. Epub 2007 Aug 2.
Title: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice.
Author: Lee, Sei-Jung|Lim, Kye-Taek
PMID: 17868752
Journal: Mol Cancer Ther. 2007 Oct;6(10):2786-97.
Title: Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway.
Author: Lee, Seung Ho|Son, Seung Mo|Son, Dong Ju|Kim, Sun Mi|Kim, Tack Joong|Song, Sukgil|Moon, Dong Cheul|Lee, Hyo Won|Ryu, Jae Chun|Yoon, Do-Young|Hong, Jin Tae
PMID: 17938270
Journal: Neoplasma. 2007;54(6):495-502.
Title: Sensitization of colorectal cancer cells to irradiation by IL-4 and IL-10 is associated with inhibition of NF-kappaB.
Author: Voboril, R|Weberova-Voborilova, J
PMID: 17949233
Journal: Cancer Chemother Pharmacol. 2008 Feb;61(2):189-201.
Title: Cell death in response to antimetabolites directed at thymidylate synthase.
Author: Barbour, Karen W|Berger, Franklin G
PMID: 17396263
Journal: J Biol Chem. 2008 Feb 15;283(7):4094-104. Epub 2007 Dec 15.
Title: Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells.
Author: Kang, Dong Woo|Park, Mi Hee|Lee, Young Jun|Kim, Hyung Sik|Kwon, Taeg Kyu|Park, Won-Sang|Min, Do Sik
PMID: 18084005
Journal: Eur J Pharmacol. 2008 Mar 17;582(1-3):17-25.
Title: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.
Author: Lee, So Yong|Yuk, Dong Yeon|Song, Ho Seub|Yoon, Do Young|Jung, Jae Kyung|Moon, Dong Cheul|Lee, Byung Seok|Hong, Jin Tae
PMID: 18241858
Journal: Clin Cancer Res. 2008 Mar 15;14(6):1788-96.
Title: Irinotecan pharmacogenetics: influence of pharmacodynamic genes.
Author: Hoskins, Janelle M|Marcuello, Eugenio|Altes, Albert|Marsh, Sharon|Maxwell, Taylor|Van Booven, Derek J|Pare, Laia|Culverhouse, Robert|McLeod, Howard L|Baiget, Montserrat
PMID: 18347181
Journal: Mol Cancer Res. 2008 Jul;6(7):1178-84.
Title: Increased Rac1b expression sustains colorectal tumor cell survival.
Author: Matos, Paulo|Jordan, Peter
PMID: 18644982
Journal: Cell Biol Int. 2008 Oct;32(10):1207-14.
Title: NF-kappaB-dependency and consequent regulation of IL-8 in echinomycin-induced apoptosis of HT-29 colon cancer cells.
Author: Park, Ju Youn|Chang, Jae-Ho|Bae, Keum Seok|Lee, Kyoung Ho|Choi, Sun Ju|Park, Joo Young|Ryang, Yong Suk|Kim, Soo-Ki
PMID: 18675368
Journal: Biochem Pharmacol. 2008 Dec 1;76(11):1485-9.
Title: Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis.
Author: Li, Wenge|Khor, Tin Oo|Xu, Changjiang|Shen, Guoxiang|Jeong, Woo-Sik|Yu, Siwang|Kong, Ah-Ng
PMID: 18694732
Journal: Acta Biochim Pol. 2008;55(4):741-8. Epub 2008 Nov 20.
Title: TNFalpha-induced activation of NFkappaB protects against UV-induced apoptosis specifically in p53-proficient cells.
Author: Szoltysek, Katarzyna|Pietranek, Katarzyna|Kalinowska-Herok, Magdalena|Pietrowska, Monika|Kimmel, Marek|Widlak, Piotr
PMID: 19023456
Journal: Korean J Gastroenterol. 2008 Dec;52(6):359-67.
Title: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa].
Author: Lee, Sang Dae
PMID: 19096253
Journal: Acta Pol Pharm. 2008 Nov-Dec;65(6):697-702.
Title: Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells.
Author: Kapral, Malgorzata|Parfiniewicz, Beata|Strzalka-Mrozik, Barbara|Zachacz, Agnieszka|Weglarz, Ludmila
PMID: 19172851
Journal: Int J Cancer. 2009 Jan 15;124(2):264-71.
Title: Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice.
Author: Kim, Mihye|Miyamoto, Shingo|Yasui, Yumiko|Oyama, Takeru|Murakami, Akira|Tanaka, Takuji
PMID: 19003968
Journal: J Nat Prod. 2009 Mar 27;72(3):396-402.
Title: Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola.
Author: Asolkar, Ratnakar N|Freel, Kelle C|Jensen, Paul R|Fenical, William|Kondratyuk, Tamara P|Park, Eun-Jung|Pezzuto, John M
PMID: 19117399
Journal: Cancer Res. 2009 May 1;69(9):3764-71.
Title: Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells.
Author: Du, Qiang|Zhang, Xinglu|Cardinal, Jon|Cao, Zongxian|Guo, Zhong|Shao, Lifang|Geller, David A
PMID: 19383900
Journal: Cancer Genet Cytogenet. 2009 Jun;191(2):73-7.
Title: A functional insertion/deletion polymorphism in the promoter region of the NFKB1 gene increases susceptibility for prostate cancer.
Author: Zhang, Peng|Wei, Qiang|Li, Xiang|Wang, Kunjie|Zeng, Hao|Bu, Hong|Li, Hong
PMID: 19446741
Journal: Biomed Environ Sci. 2009 Feb;22(1):76-85.
Title: Potential mechanisms involved in ceramide-induced apoptosis in human colon cancer HT29 cells.
Author: Wang, Jing|Lv, Xiao-Wen|Du, Yu-Guo
PMID: 19462692
Journal: Mol Cancer Ther. 2009 Jun;8(6):1613-24.
Title: Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50.
Author: Ban, Jung Ok|Oh, Ju Hoon|Hwang, Bang Yeon|Moon, Dong Cheul|Jeong, Heon-Sang|Lee, Seram|Kim, Soyoun|Lee, Hyosung|Kim, Kyung-Bo|Han, Sang Bae|Hong, Jin Tae
PMID: 19509257
Journal: Br J Cancer. 2009 Jul 7;101(1):106-15.
Title: Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue.
Author: Charalambous, M P|Lightfoot, T|Speirs, V|Horgan, K|Gooderham, N J
PMID: 19513071
Journal: Eur J Pharmacol. 2009 Sep 15;618(1-3):91-7.
Title: An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation.
Author: Joo, Kanghyun|Lee, Youna|Choi, Deakyu|Han, Jeongoh|Hong, Sungchae|Kim, Young Mi|Jung, Yunjin
PMID: 19616541
Journal: J Nat Prod. 2009 Nov;72(11):2028-31.
Title: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
Author: Han, Ah-Reum|Kim, Jeong-Ah|Lantvit, Daniel D|Kardono, Leonardus B S|Riswan, Soedarsono|Chai, Heebyung|Carcache de Blanco, Esperanza J|Farnsworth, Norman R|Swanson, Steven M|Kinghorn, A Douglas
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Journal: J Cell Mol Med. 2010 Mar;14(3):710-25.
Title: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells.
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Title: Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines.
Author: Guo, Xiaoxia|Xu, Bing|Pandey, Shuchita|Goessl, Elisabeth|Brown, James|Armesilla, Angel L|Darling, John L|Wang, Weiguang
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Journal: Mol Carcinog. 2010 Feb;49(2):121-9.
Title: Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma.
Author: Lauscher, Johannes C|Grone, Jorn|Dullat, Sonja|Hotz, Birgit|Ritz, Jorg-P|Steinhoff, Ulrich|Buhr, Heinz-J|Visekruna, Alexander
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Journal: BioDrugs. 2010 Apr 1;24(2):131-46.
Title: Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter.
Author: Teimoori-Toolabi, Ladan|Azadmanesh, Kayhan|Amanzadeh, Amir|Zeinali, Sirous
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Journal: Cell Cycle. 2010 Apr 1;9(7):1253-62.
Title: Netrin-1, a missing link between chronic inflammation and tumor progression.
Author: Paradisi, Andrea|Mehlen, Patrick
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Journal: J Nat Prod. 2010 May 28;73(5):949-55.
Title: Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.
Author: Ren, Yulin|Kardono, Leonardus B S|Riswan, Soedarsono|Chai, Heebyung|Farnsworth, Norman R|Soejarto, Djaja D|Carcache de Blanco, Esperanza J|Kinghorn, A Douglas
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Journal: Oncology. 2010;78(3-4):181-8.
Title: NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer.
Author: Puvvada, Soham D|Funkhouser, William K|Greene, Kevin|Deal, Allison|Chu, Haitao|Baldwin, Albert S|Tepper, Joel E|O'Neil, Bert H
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Journal: Mol Cell Biochem. 2010 Sep;342(1-2):63-70.
Title: 17beta-estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells.
Author: Lai, Tung-Yuan|Chen, Li-Mien|Lin, Jing-Ying|Tzang, Bor-Show|Lin, James A|Tsai, Chang-Hai|Lin, Yueh-Min|Huang, Chih-Yang|Liu, Chung-Jung|Hsu, Hsi-Hsien
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Journal: Int J Biochem Cell Biol. 2010 Oct;42(10):1571-5.
Title: Colorectal carcinoma cells--regulation of survival and growth by SGK1.
Author: Lang, Florian|Perrotti, Nicola|Stournaras, Christos
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Journal: BMC Cancer. 2010 Jul 24;10:392.
Title: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1.
Author: Kwon, Ho-Keun|Hwang, Ji-Sun|So, Jae-Seon|Lee, Choong-Gu|Sahoo, Anupama|Ryu, Jae-Ha|Jeon, Won Kyung|Ko, Byoung Seob|Im, Chang-Rok|Lee, Sung Haeng|Park, Zee Yong|Im, Sin-Hyeog
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Journal: Int J Colorectal Dis. 2010 Dec;25(12):1407-15.
Title: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism.
Author: Jin, Heiying|Tan, Xuanzhong|Liu, Xiufang|Ding, Yijiang
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Journal: BMC Cancer. 2010 Sep 13;10:484.
Title: Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes.
Author: Andersen, Vibeke|Christensen, Jane|Overvad, Kim|Tjonneland, Anne|Vogel, Ulla
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Journal: BMC Med Genet. 2010 Dec 3;11:170.
Title: Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor.
Author: Curtin, Karen|Wolff, Roger K|Herrick, Jennifer S|Abo, Ryan|Slattery, Martha L
PMID: 21129206
Journal: Folia Microbiol (Praha). 2010 Nov;55(6):657-61.
Title: Quantitative evaluation of transcriptional activation of NF-kappaB p65 and p50 subunits and IkappaBalpha encoding genes in colon cancer cells by Desulfovibrio desulfuricans endotoxin.
Author: Kapral, M|Weglarz, L|Parfiniewicz, B|Lodowska, J|Jaworska-Kik, M
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Journal: Biomedica. 2010 Oct-Dec;30(4):577-86.
Title: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells.
Author: Maldonado, Maria Elena|Bousserouel, Souad|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 21713362
Journal: Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):705-11.
Title: Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy.
Author: O'Neil, Bert H|Funkhouser, William K|Calvo, Benjamin F|Meyers, Michael O|Kim, Hong Jin|Goldberg, Richard M|Bernard, Stephen A|Caskey, Laura|Deal, Allison M|Wright, Fred|Baldwin, Albert S|Tepper, Joel E
PMID: 20630669
Journal: Mol Nutr Food Res. 2011 Feb;55(2):198-208.
Title: Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo.
Author: Gosslau, Alexander|En Jao, David Li|Huang, Mou-Tuan|Ho, Chi-Tan|Evans, Dave|Rawson, Nancy E|Chen, Kuang Yu
PMID: 20669245
Journal: Int J Cancer. 2011 Jun 1;128(11):2581-90.
Title: NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Author: Wang, Rong|Dashwood, Wan-Mohaiza|Nian, Hui|Lohr, Christiane V|Fischer, Kay A|Tsuchiya, Naoto|Nakagama, Hitoshi|Ashktorab, Hassan|Dashwood, Roderick H
PMID: 20715105
Journal: Exp Cell Res. 2011 Jun 10;317(10):1359-67.
Title: Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action.
Author: Williams, Jennie L|Ji, Ping|Ouyang, Nengtai|Kopelovich, Levy|Rigas, Basil
PMID: 21406194
Journal: Cell Cycle. 2011 May 15;10(10):1545-7. Epub 2011 May 15.
Title: Antagonistic crosstalk between APC and HIF-1alpha.
Author: Nathke, Inke|Rocha, Sonia
PMID: 21502812
Journal: Biochim Biophys Acta. 2011 Aug;1812(8):851-8.
Title: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-kappaB signaling in the intestine.
Author: Gadaleta, Raffaella M|Oldenburg, Bas|Willemsen, Ellen C L|Spit, Maureen|Murzilli, Stefania|Salvatore, Lorena|Klomp, Leo W J|Siersema, Peter D|van Erpecum, Karel J|van Mil, Saskia W C
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Journal: J Cell Biochem. 2011 Sep;112(9):2490-501.
Title: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma.
Author: Cimen, I|Astarci, E|Banerjee, S
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Journal: J Exp Clin Cancer Res. 2011 May 17;30:59.
Title: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity.
Author: Ritchie, Shawn A|Jayasinghe, Dushmanthi|Davies, Gerald F|Ahiahonu, Pearson|Ma, Hong|Goodenowe, Dayan B
PMID: 21586136
Journal: Front Physiol. 2011 May 5;2:17.
Title: Extracellular Calcium-Sensing Receptor Inhibition of Intestinal EpithelialTNF Signaling Requires CaSR-Mediated Wnt5a/Ror2 Interaction.
Author: Kelly, Jacqueline C|Lungchukiet, P|Macleod, R John
PMID: 21603229
Journal: BMC Cancer. 2011 Jul 1;11:285.
Title: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3.
Author: Porquet, Nicolas|Poirier, Andree|Houle, Francois|Pin, Anne-Laure|Gout, Stephanie|Tremblay, Pierre-Luc|Paquet, Eric R|Klinck, Roscoe|Auger, Francois A|Huot, Jacques
PMID: 21722370
Journal: PLoS One. 2011;6(6):e21726.
Title: NFkappaB1 and NFkappaBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population.
Author: Song, Shunxin|Chen, Dianke|Lu, Jiachun|Liao, Jiawei|Luo, Yanxin|Yang, Zuli|Fu, Xinhui|Fan, Xinjuan|Wei, Yisheng|Yang, Lei|Wang, Lei|Wang, Jianping
PMID: 21738780
Journal: Cancer Biol Ther. 2011 Nov 1;12(9):797-807.
Title: C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFkappaB in colon cancer cells and xenograft tumors.
Author: Chen, Chun|Liu, Yang|Chen, Yuanzhong|Xu, Jianhua
PMID: 21900746
Journal: Cancer Lett. 2011 Dec 27;313(2):167-80.
Title: Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to alpha5beta1 integrin and suppresses FAK/ERK/NF-kappaB signaling.
Author: Dia, Vermont P|Gonzalez de Mejia, Elvira
PMID: 21963225
Journal: Clin Cancer Res. 2011 Nov 15;17(22):7139-47.
Title: Genetic variation in inflammatory pathways is related to colorectal cancer survival.
Author: Coghill, Anna E|Newcomb, Polly A|Poole, Elizabeth M|Hutter, Carolyn M|Makar, Karen W|Duggan, Dave|Potter, John D|Ulrich, Cornelia M
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Journal: Mol Cancer Res. 2011 Dec;9(12):1718-31.
Title: Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells.
Author: Hamilton, Kathryn E|Simmons, James G|Ding, Shengli|Van Landeghem, Laurianne|Lund, P Kay
PMID: 21994466
Journal: Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):473-84.
Title: Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer.
Author: Schror, Karsten
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Journal: Mol Carcinog. 2012 Jun;51(6):475-90.
Title: Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells.
Author: Babykutty, Suboj|S, Priya P|J, Nandini R|Kumar, M A Suresh|Nair, Mangalam S|Srinivas, Priya|Gopala, Srinivas
PMID: 21678498
Journal: Oncogene. 2012 May 31;31(22):2761-72.
Title: BAG-1 interacts with the p50-p50 homodimeric NF-kappaB complex: implications for colorectal carcinogenesis.
Author: Southern, S L|Collard, T J|Urban, B C|Skeen, V R|Smartt, H J|Hague, A|Oakley, F|Townsend, P A|Perkins, N D|Paraskeva, C|Williams, A C
PMID: 21963853
Journal: J Gastroenterol Hepatol. 2012 Jan;27(1):39-50.
Title: Colorectal cancer mouse models: integrating inflammation and the stroma.
Author: Ernst, Matthias|Ramsay, Robert G
PMID: 22188027
Journal: Mol Cancer. 2012 Jan 4;11:1.
Title: Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Author: Hummon, Amanda B|Pitt, Jason J|Camps, Jordi|Emons, Georg|Skube, Susan B|Huppi, Konrad|Jones, Tamara L|Beissbarth, Tim|Kramer, Frank|Grade, Marian|Difilippantonio, Michael J|Ried, Thomas|Caplen, Natasha J
PMID: 22216762
Journal: PLoS One. 2012;7(1):e29532.
Title: A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.
Author: Al-Mulla, Fahd|Bitar, Milad S|Feng, Jingwei|Park, Sungdae|Yeung, Kam C
PMID: 22279539
Journal: J Agric Food Chem. 2012 Apr 4;60(13):3441-51.
Title: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.
Author: Chiou, Yi-Shiou|Ma, Nianhan Jia-Lin|Sang, Shengmin|Ho, Chi-Tang|Wang, Ying-Jan|Pan, Min-Hsiung
PMID: 22409325
Journal: PLoS One. 2012;7(4):e33031.
Title: Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines.
Author: De Stefano, Daniela|Tommonaro, Giuseppina|Malik, Shoaib Ahmad|Iodice, Carmine|De Rosa, Salvatore|Maiuri, Maria Chiara|Carnuccio, Rosa
PMID: 22509253
Journal: Ann Hum Genet. 2012 Jul;76(4):269-76.
Title: The joint association of REST and NFKB1 polymorphisms on the risk of colorectal cancer.
Author: Yu, Yunxian|Liu, Hui|Jin, Mingjuan|Zhang, Mingwu|Pan, Yifeng|Zhang, Shanchun|Li, Qilong|Chen, Kun
PMID: 22530801
Journal: Eur J Pharmacol. 2012 Aug 5;688(1-3):14-21.
Title: The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells.
Author: Chidambara Murthy, Kotamballi N|Jayaprakasha, Guddadarangavvanahally K|Patil, Bhimanagouda S
PMID: 22617025
Journal: Cell Cycle. 2012 Nov 1;11(21):3997-4008.
Title: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.
Author: Werneck, Miriam B F|Hottz, Eugenio|Bozza, Patricia T|Viola, Joao P B
PMID: 22992618
Journal: Biochem Biophys Res Commun. 2012 Nov 16;428(2):210-5.
Title: Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155.
Author: Pu, Jun|Bai, Danna|Yang, Xia|Lu, Xiaozhao|Xu, Lijuan|Lu, Jianguo
PMID: 23036199
Journal: PLoS One. 2012;7(10):e48208.
Title: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Jutooru, Indira|Chadalapaka, Gayathri|Nair, Vijayalekshmi|Lee, Syng-Ook|Safe, Stephen
PMID: 23110215
Journal: BMC Cancer. 2012 Nov 30;12:564.
Title: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
Author: Gandhy, Shruti U|Kim, Kyounghyun|Larsen, Lesley|Rosengren, Rhonda J|Safe, Stephen
PMID: 23194063
Journal: Oncoimmunology. 2012 Dec 1;1(9):1495-1506.
Title: A TLR4-interacting peptide inhibits lipopolysaccharide-stimulated inflammatory responses, migration and invasion of colon cancer SW480 cells.
Author: Rakhesh, Madhusoodhanan|Cate, Moriasi|Vijay, Ramani|Shrikant, Anant|Shanjana, Awasthi
PMID: 23264896
Journal: Mol Carcinog. 2013 Mar;52(3):195-206.
Title: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling.
Author: Raina, Komal|Agarwal, Chapla|Agarwal, Rajesh
PMID: 22086675
Journal: Carcinogenesis. 2013 Jan;34(1):79-85.
Title: IkappaBKbeta and NFkappaB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry.
Author: Seufert, Brenna L|Poole, Elizabeth M|Whitton, John|Xiao, Liren|Makar, Karen W|Campbell, Peter T|Kulmacz, Richard J|Baron, John A|Newcomb, Polly A|Slattery, Martha L|Potter, John D|Ulrich, Cornelia M
PMID: 23002237
Journal: Aliment Pharmacol Ther. 2013 Feb;37(4):383-91.
Title: Systematic review: diet-gene interactions and the risk of colorectal cancer.
Author: Andersen, V|Holst, R|Vogel, U
PMID: 23216531
Journal: PLoS One. 2013;8(3):e58733.
Title: Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.
Author: Meunier, Charles|Van Der Kraak, Lauren|Turbide, Claire|Groulx, Normand|Labouba, Ingrid|Cingolani, Pablo|Blanchette, Mathieu|Yeretssian, Garabet|Mes-Masson, Anne-Marie|Saleh, Maya|Beauchemin, Nicole|Gros, Philippe
PMID: 23516545
Journal: Mol Cell Biochem. 2013 Jul;379(1-2):171-80.
Title: Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFkappaB activity.
Author: Han, Peng|Luan, Ying|Liu, Yanlong|Yu, Zhiwei|Li, Jingwen|Sun, Zicheng|Chen, Gang|Cui, Binbin
PMID: 23559092
Journal: Cancer Lett. 2013 Aug 9;336(1):127-39.
Title: 6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor gamma (PPARgamma).
Author: Tan, Boon Shing|Kang, Owen|Mai, Chun Wai|Tiong, Kai Hung|Khoo, Alan Soo-Beng|Pichika, Mallikarjuna Rao|Bradshaw, Tracey D|Leong, Chee-Onn
PMID: 23612072
Journal: PLoS One. 2013 May 6;8(5):e62223.
Title: A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.
Author: Shao, Ling|Oshima, Shigeru|Duong, Bao|Advincula, Rommel|Barrera, Julio|Malynn, Barbara A|Ma, Averil
PMID: 23671587
Journal: Pharm Biol. 2013 Sep;51(9):1110-24.
Title: Syringic acid from Tamarix aucheriana possesses antimitogenic and chemo-sensitizing activities in human colorectal cancer cells.
Author: Abaza, Mohamed-Salah|Al-Attiyah, Raja'a|Bhardwaj, Radhika|Abbadi, Ghaneim|Koyippally, Mathew|Afzal, Mohammad
PMID: 23745612
Journal: Cancer Epidemiol. 2013 Oct;37(5):634-8.
Title: The functional -94 insertion/deletion ATTG polymorphism in the promoter region of NFKB1 gene increases the risk of sporadic colorectal cancer.
Author: Mohd Suzairi, Mohd Shafi'i|Tan, Shing Cheng|Ahmad Aizat, Abdul Aziz|Mohd Aminudin, Mustapha|Siti Nurfatimah, Mohd Shahpudin|Andee, Zakaria Dzulkarnaen|Ankathil, Ravindran
PMID: 23806437
Journal: J Vet Sci. 2013;14(4):387-93. Epub 2013 Jun 30.
Title: Chemopreventive and metabolic effects of inulin on colon cancer development.
Author: Hijova, Emilia|Szabadosova, Viktoria|Stofilova, Jana|Hrckova, Gabriela
PMID: 23820222
Journal: Nutr Cancer. 2013;65(6):908-18.
Title: Mechanisms involved in the antiproliferative and proapoptotic effects of unsaponifiable fraction of extra virgin olive oil on HT-29 cancer cells.
Author: Cardeno, Ana|Sanchez-Hidalgo, Marina|Cortes-Delgado, Amparo|Alarcon de la Lastra, Catalina
PMID: 23909736
Journal: PLoS One. 2013 Aug 19;8(8):e72119.
Title: Low ABCB1 gene expression is an early event in colorectal carcinogenesis.
Author: Andersen, Vibeke|Vogel, Ulla|Godiksen, Sine|Frenzel, Franz B|Saebo, Mona|Hamfjord, Julian|Kure, Elin|Vogel, Lotte K
PMID: 23977225
Journal: Chemotherapy. 2013;59(2):112-20.
Title: Acidic pH of tumor microenvironment enhances cytotoxicity of the disulfiram/Cu2+ complex to breast and colon cancer cells.
Author: Navratilova, Jarmila|Hankeova, Tereza|Benes, Petr|Smarda, Jan
PMID: 24051574
Journal: Int J Cancer Res. 2013;9(2):36-53.
Title: Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo.
Author: Acuna, Ulyana Munoz|Shen, Qi|Ren, Yulin|Lantvit, Daniel D|Wittwer, Jennifer A|Kinghorn, A Douglas|Swanson, Steven M|de Blanco, Esperanza J Carcache
PMID: 25621077
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E53-61.
Title: Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Li, Xi|Safe, Stephen
PMID: 23670891
Journal: Biol Pharm Bull. 2014;37(1):137-44. Epub 2013 Oct 19.
Title: In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages.
Author: Kono, Yusuke|Kawakami, Shigeru|Higuchi, Yuriko|Yamashita, Fumiyoshi|Hashida, Mitsuru
PMID: 24141263
Journal: Bratisl Lek Listy. 2014;115(2):76-9.
Title: Changes chemopreventive markers in colorectal cancer development after inulin supplementation.
Author: Hijova, E|Szabadosova, V|Strojny, L|Bomba, A
PMID: 24601699
Journal: Virchows Arch. 2014 Jun;464(6):645-54.
Title: Prognostic value of c-FLIPL/s, HIF-1alpha, and NF-kappabeta in stage II and III rectal cancer.
Author: Novell, Anna|Martinez-Alonso, Montserrat|Mira, Moises|Tarragona, Jordi|Salud, Antonieta|Matias-Guiu, Xavier
PMID: 24711168
Journal: Cancer Invest. 2014 Aug;32(7):311-20.
Title: Association between the NFKB1-94ins/del ATTG polymorphism and cancer risk: an updated meta-analysis.
Author: Duan, Wenyuan|Wang, Erli|Zhang, Fengquan|Wang, Tongjian|You, Xiangdong|Qiao, Bin
PMID: 24827594
Journal: J Cancer. 2014 Apr 25;5(6):406-16.
Title: Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms.
Author: Doudican, Nicole A|Mazumder, Amitabha|Kapoor, Shweta|Sultana, Zeba|Kumar, Ansu|Talawdekar, Anay|Basu, Kabya|Agrawal, Ashish|Aggarwal, Aditi|Shetty, Krithika|Singh, Neeraj K|Kumar, Chandan|Tyagi, Anuj|Singh, Neeraj Kumar|Darlybai, Janitha C|Abbasi, Taher|V
PMID: 24847381
Journal: Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.
Title: Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.
Author: Slattery, Martha L|Lundgreen, Abbie|Mullany, Lila E|Penney, Rosalind B|Wolff, Roger K
PMID: 24959314
Journal: Pharmgenomics Pers Med. 2014 Jul 14;7:163-71.
Title: CYP19A1 single nucleotide polymorphism associations with CYP19A1, NFkappaB1, and IL6 gene expression in human normal colon and normal liver samples.
Author: Penney, Rosalind B|Lundgreen, Abbie|Yao-Borengasser, Aiwei|Edavana, Vineetha K|Williams, Suzanne|Dhakal, Ishwori|Wolff, Roger K|Kadlubar, Susan|Slattery, Martha L
PMID: 25114581
Journal: BMC Cancer. 2014 Sep 7;14:656.
Title: MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer.
Author: Molina-Pinelo, Sonia|Carnero, Amancio|Rivera, Fernando|Estevez-Garcia, Purificacion|Bozada, Juan Manuel|Limon, Maria Luisa|Benavent, Marta|Gomez, Javier|Pastor, Maria Dolores|Chaves, Manuel|Suarez, Rocio|Paz-Ares, Luis|de la Portilla, Fernando|Carranza-Ca
PMID: 25197016
Journal: BMC Cell Biol. 2014 Oct 10;15:36.
Title: Cell specific apoptosis by RLX is mediated by NFkappaB in human colon carcinoma HCT-116 cells.
Author: Qazi, Asif Khurshid|Hussain, Aashiq|Aga, Mushtaq A|Ali, Shakir|Taneja, Subhash Chandra|Sharma, Parduman Raj|Saxena, Ajit Kumar|Mondhe, Dilip M|Hamid, Abid
PMID: 25303828
Journal: Int J Radiat Oncol Biol Phys. 2014 Nov 1;90(3):595-602.
Title: Role of genetic polymorphisms in NFKB-mediated inflammatory pathways in response to primary chemoradiation therapy for rectal cancer.
Author: Dzhugashvili, Maia|Luengo-Gil, Gines|Garcia, Teresa|Gonzalez-Conejero, Rocio|Conesa-Zamora, Pablo|Escolar, Pedro Pablo|Calvo, Felipe|Vicente, Vicente|Ayala de la Pena, Francisco
PMID: 25304949
Journal: Mol Cells. 2014 Dec 31;37(12):899-906.
Title: Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines.
Author: Shehzad, Adeeb|Ul Islam, Salman|Lee, Jaetae|Lee, Young Sup
PMID: 25431425
Journal: Genes Nutr. 2015 Jan;10(1):448.
Title: Interactions between meat intake and genetic variation in relation to colorectal cancer.
Author: Andersen, Vibeke|Vogel, Ulla
PMID: 25491747
Journal: Oncotarget. 2015 Mar 20;6(8):6160-78.
Title: Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFkappaB signaling.
Author: Zhang, Yonggang|Liu, Shu|Wang, Hong|Yang, Wensheng|Li, Fang|Yang, Fan|Yu, Daohai|Ramsey, Frederick V|Tuszyski, George P|Hu, Wenhui
PMID: 25704885
Journal: PLoS One. 2015 Feb 23;10(2):e0116394.
Title: Polymorphisms in NFKB1 and TLR4 and interaction with dietary and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study.
Author: Kopp, Tine Iskov|Andersen, Vibeke|Tjonneland, Anne|Vogel, Ulla
PMID: 25705893
Journal: J Pathol. 2015 Jul;236(3):326-36.
Title: NF-kappaB1, NF-kappaB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.
Author: Burkitt, Michael D|Hanedi, Abdalla F|Duckworth, Carrie A|Williams, Jonathan M|Tang, Joseph M|O'Reilly, Lorraine A|Putoczki, Tracy L|Gerondakis, Steve|Dimaline, Rod|Caamano, Jorge H|Pritchard, D Mark
PMID: 25727407
Journal: Nutr Cancer. 2015;67(4):620-36.
Title: Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors.
Author: Saini, Manpreet Kaur|Sanyal, Sankar Nath
PMID: 25825916
Journal: J Biol Inorg Chem. 2015 Jul;20(5):855-73.
Title: Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-kappaB activation pathway and ubiquitination.
Author: Ooi, Kah Kooi|Yeo, Chien Ing|Ang, Kok-Pian|Akim, Abdah Md|Cheah, Yoke-Kqueen|Halim, Siti Nadiah Abdul|Seng, Hoi-Ling|Tiekink, Edward R T
PMID: 26003312
Journal: PLoS One. 2015 Jun 1;10(6):e0126645.
Title: Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.
Author: Papaianni, Emanuela|El Maadidi, Souhayla|Schejtman, Andrea|Neumann, Simon|Maurer, Ulrich|Marino-Merlo, Francesca|Mastino, Antonio|Borner, Christoph
PMID: 26030884
Journal: Sci Rep. 2015 Jun 9;5:11187.
Title: Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRalpha/c-SRC/ERK1/2/NFkappaB/TP53 pathway: in vitro and in vivo studies.
Author: Kuo, Chun-Ting|Chang, Chieh|Lee, Wen-Sen
PMID: 26056802
Journal: Mutat Res. 2015 Aug;778:61-70.
Title: The different radiation response and radiation-induced bystander effects in colorectal carcinoma cells differing in p53 status.
Author: Widel, Maria|Lalik, Anna|Krzywon, Aleksandra|Poleszczuk, Jan|Fujarewicz, Krzysztof|Rzeszowska-Wolny, Joanna
PMID: 26099456
Journal: Mol Cancer. 2015 Jun 30;14:124.
Title: Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression.
Author: Park, Mi Hee|Hong, Ji Eun|Park, Eun Sook|Yoon, Hee Sung|Seo, Doo Won|Hyun, Byung Kook|Han, Sang-Bae|Ham, Young Won|Hwang, Bang Yeon|Hong, Jin Tae
PMID: 26123287
Journal: PLoS One. 2015 Jul 2;10(7):e0131699.
Title: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line.
Author: Furi, Istvan|Kalmar, Alexandra|Wichmann, Barnabas|Spisak, Sandor|Scholler, Andrea|Bartak, Barbara|Tulassay, Zsolt|Molnar, Bela
PMID: 26133168
Journal: Growth Horm IGF Res. 2015 Oct;25(5):253-61.
Title: Crosstalk between the TNF and IGF pathways enhances NF-kappaB activation and signaling in cancer cells.
Author: Li, Shun|Pinard, Maxime|Wang, Yunling|Yang, Long|Lin, Rongtuan|Hiscott, John|Su, Bing|Brodt, Pnina
PMID: 26239406
Journal: Gastroenterology. 2015 Dec;149(7):1860-1871.e8.
Title: Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
Author: Zhao, Junjie|Bulek, Katarzyna|Gulen, Muhammet F|Zepp, Jarod A|Karagkounis, Georgio|Martin, Bradley N|Zhou, Hao|Yu, Minjia|Liu, Xiuli|Huang, Emina|Fox, Paul L|Kalady, Matthew F|Markowitz, Sanford D|Li, Xiaoxia
PMID: 26344057
Journal: Front Genet. 2015 Sep 15;6:288.
Title: Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways.
Author: Suleiman, Suleiman H|Koko, Mahmoud E|Nasir, Wafaa H|Elfateh, Ommnyiah|Elgizouli, Ubai K|Abdallah, Mohammed O E|Alfarouk, Khalid O|Hussain, Ayman|Faisal, Shima|Ibrahim, Fathelrahamn M A|Romano, Maurizio|Sultan, Ali|Banks, Lawrence|Newport, Melanie|Baralle,
PMID: 26442106
Journal: Oncotarget. 2015 Dec 8;6(39):41929-43.
Title: (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice.
Author: Zheng, Jie|Park, Mi Hee|Son, Dong Ju|Choi, Min Gi|Choi, Jeong Soon|Nam, Kyung Tak|Kim, Hae Deun|Rodriguez, Kevin|Gann, Benjamin|Ham, Young Wan|Han, Sang Bae|Hong, Jin Tae
PMID: 26474284
Journal: BMC Cancer. 2015 Oct 23;15:770.
Title: The NF-kappaB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription.
Author: Simon, Priscilla S|Sharman, Sarah K|Lu, Chunwan|Yang, Dafeng|Paschall, Amy V|Tulachan, Sidhartha S|Liu, Kebin
PMID: 26497740
Journal: Int J Cancer Res (Tortola). 2015 Mar;49(1):1655-1662.
Title: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells.
Author: Acuna, Ulyana Munoz|Zi, Jiachen|Orjala, Jimmy|Carcache de Blanco, Esperanza J
PMID: 26753095
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2015 Nov;35(11):1356-60.
Title: [Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes].
Author: Chen, Jin-tuan|Ke, Xiao|Zhang, Xin|Fang, Wen-yi|Yang, Chun-bo|Peng, Jun|Chen, You-qin|Speerra, Thomas J
PMID: 26775485
Journal: Cancer Cell Int. 2016 Feb 2;16:1.
Title: Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy.
Author: Riahi-Chebbi, Ichrak|Haoues, Meriam|Essafi, Makram|Zakraoui, Ons|Fattouch, Sami|Karoui, Habib|Essafi-Benkhadir, Khadija
PMID: 26839513
Journal: J Cell Biochem. 2016 Jun;117(6):1471-81.
Title: Evodiamine Suppresses ABCG2 Mediated Drug Resistance by Inhibiting p50/p65 NF-kappaB Pathway in Colorectal Cancer.
Author: Sui, Hua|Zhou, Li-Hong|Zhang, Ya-Li|Huang, Jian-Ping|Liu, Xuan|Ji, Qing|Fu, Xiao-Ling|Wen, Hao-Tian|Chen, Zhe-Sheng|Deng, Wan-Li|Zhu, Hui-Rong|Li, Qi
PMID: 26590365
Journal: Cell Rep. 2016 Feb 16;14(6):1462-1476.
Title: RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer.
Author: Tarcic, Ohad|Pateras, Ioannis S|Cooks, Tomer|Shema, Efrat|Kanterman, Julia|Ashkenazi, Hadas|Boocholez, Hana|Hubert, Ayala|Rotkopf, Ron|Baniyash, Michal|Pikarsky, Eli|Gorgoulis, Vassilis G|Oren, Moshe
PMID: 26854224
Journal: Oncol Res. 2016;23(5):249-56.
Title: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression.
Author: Ren, Hongtao|Wang, Zhongwei|Zhang, Shuqun|Ma, Hongbing|Wang, Yali|Jia, Lijun|Li, Yiming
PMID: 27098148
Journal: Mol Med Rep. 2016 Jun;13(6):5379-85.
Title: NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-kappaB pathway.
Author: Xu, Chun-Yan|Qin, Meng-Bin|Tan, Lin|Liu, Shi-Quan|Huang, Jie-An
PMID: 27109343
Journal: Mol Pharm. 2016 Jun 6;13(6):2126-35.
Title: 5-Aminosalicylic Acid Azo-Linked to Procainamide Acts as an Anticolitic Mutual Prodrug via Additive Inhibition of Nuclear Factor kappaB.
Author: Kim, Wooseong|Nam, Joon|Lee, Sunyoung|Jeong, Seongkeun|Jung, Yunjin
PMID: 27112518
Journal: Postepy Hig Med Dosw (Online). 2016 Apr 27;70:360-6.
Title: [The role of inflammation in colon cancer pathogenesis].
Author: Francuz, Tomasz|Czajka-Francuz, Paulina|Cison-Jurek, Sylwia|Wojnar, Jerzy
PMID: 27117112
Journal: Oncogene. 2016 Dec 1;35(48):6203-6211.
Title: The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells.
Author: Tang, W|Wang, H|Ha, H L|Tassi, I|Bhardwaj, R|Claudio, E|Siebenlist, U
PMID: 27132515
Journal: Am J Transl Res. 2016 Feb 15;8(2):405-18. eCollection 2016.
Title: DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFkappab negative regulator PPM1B.
Author: Wang, Haiyu|Chen, Yusheng|Han, Jun|Meng, Qingyang|Xi, Qiulei|Wu, Guohao|Zhang, Bo
PMID: 27158335
Journal: Cancer Lett. 2016 Aug 10;378(2):104-10.
Title: Progesterone receptor activation is required for folic acid-induced anti-proliferation in colorectal cancer cell lines.
Author: Kuo, Chun-Ting|Lee, Wen-Sen
PMID: 27233474
Journal: Oncotarget. 2016 Oct 4;7(40):65676-65695.
Title: SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.
Author: Gagne-Sansfacon, Jessica|Coulombe, Genevieve|Langlois, Marie-Josee|Langlois, Ariane|Paquet, Marilene|Carrier, Julie|Feng, Gen-Sheng|Qu, Cheng-Kui|Rivard, Nathalie
PMID: 27582544
Journal: Food Funct. 2016 Dec 7;7(12):4823-4829.
Title: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells.
Author: Kong, Chang-Suk|Kim, You Ah|Kim, Hojun|Seo, Youngwan
PMID: 27808331
Journal: Arch Toxicol. 2017 Mar;91(3):1485-1495.
Title: Cytotoxic effects of the anthraquinone derivatives 1'-deoxyrhodoptilometrin and (S)-(-)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.
Author: Watjen, Wim|Ebada, Sherif S|Bergermann, Anja|Chovolou, Yvonni|Totzke, Frank|Kubbutat, Michael H G|Lin, Wenhan|Proksch, Peter
PMID: 27473261
Journal: PLoS One. 2017 Jan 9;12(1):e0168989.
Title: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author: Huang, Wen-Shih|Kuo, Yi-Hung|Kuo, Hsing-Chun|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Lee, Ko-Chao|Lee, Kam-Fai|Shen, Chien-Heng|Tung, Shui-Yi|Teng, Chih-Chuan
PMID: 28068431
Journal: PLoS One. 2017 Jan 20;12(1):e0170551.
Title: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.
Author: Soo, Hsien-Chuen|Chung, Felicia Fei-Lei|Lim, Kuan-Hon|Yap, Veronica Alicia|Bradshaw, Tracey D|Hii, Ling-Wei|Tan, Si-Hoey|See, Sze-Jia|Tan, Yuen-Fen|Leong, Chee-Onn|Mai, Chun-Wai
PMID: 28107519
Journal: Mol Cancer Res. 2017 Apr;15(4):467-477.
Title: Inflammatory Molecule, PSGL-1, Deficiency Activates Macrophages to Promote Colorectal Cancer Growth through NFkappaB Signaling.
Author: Li, Jiangchao|Zhou, Zeqi|Zhang, Xiaohan|Zheng, Li|He, Dan|Ye, Yuxiang|Zhang, Qian-Qian|Qi, Cui-Ling|He, Xiao-Dong|Yu, Chen|Shao, Chun-Kui|Qiao, Liang|Wang, Lijing
PMID: 28108624
Journal: Sci Rep. 2017 Mar 31;7:45648.
Title: Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation.
Author: Lu, Xiaozhao|Bai, Danna|Liu, Xiangwei|Zhou, Chen|Yang, Guodong
PMID: 28361920
Journal: Eur J Pharm Biopharm. 2017 Aug;117:346-362.
Title: Curcumin loading potentiates the chemotherapeutic efficacy of selenium nanoparticles in HCT116 cells and Ehrlich's ascites carcinoma bearing mice.
Author: Kumari, Manisha|Ray, L|Purohit, M P|Patnaik, S|Pant, A B|Shukla, Y|Kumar, P|Gupta, K C
PMID: 28499854
Journal: PLoS One. 2017 May 25;12(5):e0178444.
Title: Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women.
Author: Wang, Xiaoliang|Shojaie, Ali|Zhang, Yuzheng|Shelley, David|Lampe, Paul D|Levy, Lisa|Peters, Ulrike|Potter, John D|White, Emily|Lampe, Johanna W
PMID: 28542447
Journal: Bioorg Med Chem. 2017 Jul 15;25(14):3694-3705.
Title: Succinamide derivatives of melampomagnolide B and their anti-cancer activities.
Author: Janganati, Venumadhav|Ponder, Jessica|Thakkar, Shraddha|Jordan, Craig T|Crooks, Peter A
PMID: 28545815
Journal: Oncotarget. 2017 Jul 4;8(27):44694-44704.
Title: FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells.
Author: Liu, Shuo|Zhang, Cun|Zhang, Kuo|Gao, Yuan|Wang, Zhaowei|Li, Xiaoju|Cheng, Guang|Wang, Shuning|Xue, Xiaochang|Li, Weina|Zhang, Wei|Zhang, Yingqi|Xing, Xianghui|Li, Meng|Hao, Qiang
PMID: 28591725
Journal: Anal Chem. 2017 Jul 18;89(14):7316-7323.
Title: Sensitive and Label-Free Fluorescent Detection of Transcription Factors Based on DNA-Ag Nanoclusters Molecular Beacons and Exonuclease III-Assisted Signal Amplification.
Author: Li, Bingzhi|Xu, Lei|Chen, Yue|Zhu, Wanying|Shen, Xin|Zhu, Chunhong|Luo, Jieping|Li, Xiaoxu|Hong, Junli|Zhou, Xuemin
PMID: 28657304
Journal: Exp Ther Med. 2017 Jul;14(1):338-343.
Title: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Author: Xie, Ni|Yao, Yujiang|Wan, Lili|Zhu, Ting|Liu, Litao|Yuan, Jianhui
PMID: 28672935
Journal: Sci Rep. 2017 Jul 7;7(1):4915.
Title: The integrated pathway of TGFbeta/Snail with TNFalpha/NFkappaB may facilitate the tumor-stroma interaction in the EMT process and colorectal cancer prognosis.
Author: Li, Hui|Zhong, Anjing|Li, Si|Meng, Xianwen|Wang, Xue|Xu, Fangying|Lai, Maode
PMID: 28687755
Journal: J Ethnopharmacol. 2017 Aug 17;208:72-83.
Title: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells.
Author: Hseu, You-Cheng|Chao, Yu-Hsien|Lin, Kai-Yuan|Way, Tzong-Der|Lin, Hui-Yi|Thiyagarajan, Varadharajan|Yang, Hsin-Ling
PMID: 28688953
Journal: World J Gastroenterol. 2017 Jun 28;23(24):4341-4353.
Title: Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells.
Author: Tischlerova, Viera|Kello, Martin|Budovska, Mariana|Mojzis, Jan
PMID: 28706417
Journal: Oncotarget. 2017 May 15;8(34):56659-56671.
Title: PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition.
Author: Islam, Salman Ul|Shehzad, Adeeb|Sonn, Jong Kyung|Lee, Young Sup
PMID: 28915620
Journal: Int J Oncol. 2017 Dec;51(6):1809-1820.
Title: Parthenolide suppresses hypoxia-inducible factor-1alpha signaling and hypoxia induced epithelial-mesenchymal transition in colorectal cancer.
Author: Kim, Se Lim|Park, Young Ran|Lee, Soo Teik|Kim, Sang-Wook
PMID: 29075793
Journal: World J Gastroenterol. 2017 Oct 7;23(37):6854-6867.
Title: Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features.
Author: Marques, Diego|Ferreira-Costa, Layse Raynara|Ferreira-Costa, Lorenna Larissa|Correa, Romualdo da Silva|Borges, Aline Maciel Pinheiro|Ito, Fernanda Ribeiro|Ramos, Carlos Cesar de Oliveira|Bortolin, Raul Hernandes|Luchessi, Andre Ducati|Ribeiro-Dos-Santos,
PMID: 29085228
Journal: World J Gastroenterol. 2017 Dec 28;23(48):8533-8543.
Title: Analysis of 12 variants in the development of gastric and colorectal cancers.
Author: Cavalcante, Giovanna C|Amador, Marcos At|Ribeiro Dos Santos, Andre M|Carvalho, Darlen C|Andrade, Roberta B|Pereira, Esdras Eb|Fernandes, Marianne R|Costa, Danielle F|Santos, Ney Pc|Assumpcao, Paulo P|Ribeiro Dos Santos, Andrea|Santos, Sidney
PMID: 29358861
Journal: Carcinogenesis. 2018 Jan 12;39(1):36-46.
Title: Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
Author: Barker, Emily C|Kim, Byung-Gyu|Yoon, Ji Hee|Tochtrop, Gregory P|Letterio, John J|Choi, Sung Hee
PMID: 29069290
Journal: Cancer Lett. 2018 Feb 1;414:26-33.
Title: Chemoprevention with isothiocyanates - From bench to bedside.
Author: Grundemann, Carsten|Huber, Roman
PMID: 29111351
Journal: J Proteomics. 2018 Apr 15;177:1-10.
Title: Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model.
Author: Bucio-Noble, Daniel|Kautto, Liisa|Krisp, Christoph|Ball, Malcolm S|Molloy, Mark P
PMID: 29432917
Journal: Exp Ther Med. 2018 Mar;15(3):2655-2660.
Title: Overexpression of microRNA-15 increases the chemosensitivity of colon cancer cells to 5-fluorouracil and oxaliplatin by inhibiting the nuclear factor-kappaB signalling pathway and inducing apoptosis.
Author: Liu, Lili|Wang, Dan|Qiu, Ying|Dong, Hongyan|Zhan, Xuemei
PMID: 29467857
Journal: Mol Med Rep. 2018 Apr;17(4):5837-5843.
Title: Suppression of the NFkappaB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute.
Author: Liu, Huiping|Li, Guoning|Zhang, Bin|Sun, Deqing|Wu, Jing|Chen, Fang|Kong, Feng|Luan, Yun|Jiang, Wen|Wang, Rongmei|Xue, Xia
PMID: 29484409
Journal: J Pathol. 2018 Jun;245(2):222-234.
Title: Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers.
Author: Ye, Wen|Ling, Shaoping|Liu, Ran-Yi|Pan, Zhi-Zhong|Wang, Gaoyuan|Gao, Shijuan|Wu, Jiangxue|Cao, Lihua|Dong, Lili|Li, Yingchang|Zhou, Yi|Du, Wuying|Meng, Xiangqi|Chen, Jinna|Guan, Xinyuan|He, Yulong|Pan, Changchuan|Zheng, Xf Steven|Lu, Xuemei|Chen, Shuai|Hu
PMID: 29537081
Journal: Molecules. 2018 Mar 22;23(4). pii: molecules23040723.
Title: Food Additive Sodium Benzoate (NaB) Activates NFkappaB and Induces Apoptosis in HCT116 Cells.
Author: Yilmaz, Betul|Karabay, Arzu Zeynep
PMID: 29565269
Journal: Am J Clin Nutr. 2018 Mar 1;107(3):465-479.
Title: Meat and fiber intake and interaction with pattern recognition receptors (TLR1, TLR2, TLR4, and TLR10) in relation to colorectal cancer in a Danish prospective, case-cohort study.
Author: Kopp, Tine Iskov|Vogel, Ulla|Tjonneland, Anne|Andersen, Vibeke
PMID: 29566186
Journal: Cancer Immunol Res. 2018 May;6(5):578-593.
Title: Protumor Steering of Cancer Inflammation by p50 NF-kappaB Enhances Colorectal Cancer Progression.
Author: Porta, Chiara|Ippolito, Alessandro|Consonni, Francesca Maria|Carraro, Lorenzo|Celesti, Giuseppe|Correale, Carmen|Grizzi, Fabio|Pasqualini, Fabio|Tartari, Silvia|Rinaldi, Maurizio|Bianchi, Paolo|Balzac, Fiorella|Vetrano, Stefania|Turco, Emilia|Hirsch, Emil
PMID: 29588321
Journal: Oncol Rep. 2018 Jun;39(6):2711-2720.
Title: betaarrestin2 promotes 5FUinduced apoptosis via the NFkappaB pathway in colorectal cancer.
Author: Ren, Weixia|Wang, Tingting|He, Xiangjun|Zhang, Qi|Zhou, Jianhua|Liu, Fangfang|Gao, Fangfang|Zhang, Yujun|Liu, Yulan
PMID: 29620228
Journal: Cancer Res. 2018 Oct 1;78(19):5586-5599.
Title: A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis.
Author: Yan, Guifang|Zhao, Huakan|Zhang, Qi|Zhou, Yu|Wu, Lei|Lei, Juan|Wang, Xiang|Zhang, Jiangang|Zhang, Xiao|Zheng, Lu|Du, Guangsheng|Xiao, Weidong|Tang, Bo|Miao, Hongming|Li, Yongsheng
PMID: 30012671
Journal: Oncol Rep. 2018 Sep;40(3):1533-1544.
Title: Pin2/TRF1binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factorkappaB signaling pathway.
Author: Jiang, Tao|Li, Haiqing|Jiang, Ranran|Li, Hailong|Hou, Pingfu|Chen, Yansu|Bai, Jin|Song, Jun
PMID: 30015978
Journal: Cell Death Dis. 2018 Jul 23;9(8):798.
Title: Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer.
Author: Pal, Deeksha|Tyagi, Ashish|Chandrasekaran, Balaji|Alattasi, Houda|Ankem, Murali K|Sharma, Arun K|Damodaran, Chendil
PMID: 30038258
Journal: J Dig Dis. 2018 Jul 29.
Title: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer.
Author: Tang, Chao-Tao|Gao, Yun-Jie|Ge, Zhi-Zheng
PMID: 30058122
Journal: Int J Oncol. 2018 Oct;53(4):1469-1480.
Title: Upregulation of PDL1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300mediated NFkappaB signaling.
Author: Lucas, Justin|Hsieh, Tze-Chen|Halicka, H Dorota|Darzynkiewicz, Zbigniew|Wu, Joseph M
PMID: 30066852
Journal: Int J Oncol. 2018 Nov;53(5):2102-2110.
Title: ZBTB7 evokes 5-fluorouracil resistance in colorectal cancer through the NFkappaB signaling pathway.
Author: Wang, Zexin|Zhao, Xilan|Wang, Wei|Liu, Yishu|Li, Yanyan|Gao, Junyong|Wang, Cancan|Zhou, Meiyu|Liu, Ruyan|Xu, Guofa|Zhou, Qi
PMID: 30106136
Journal: Mol Oncol. 2018 Sep 1.
Title: miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways.
Author: Wang, Lu-Qin|Yu, Peng|Li, Bin|Guo, Yan-Hua|Liang, Zi-Rui|Zheng, Ling-Ling|Yang, Jian-Hua|Xu, Hui|Liu, Shun|Zheng, Li-Si|Zhou, Hui|Qu, Liang-Hu
PMID: 30171794
Journal: Apoptosis. 2018 Sep 8. pii: 10.1007/s10495-018-1485-4.
Title: Molecular targeting of breast and colon cancer cells by PAR1 mediated apoptosis through a novel pro-apoptotic peptide.
Author: Ray, Tanusree|Kar, Dwiprohi|Pal, Ananda|Mukherjee, Shravanti|Das, Chandrima|Pal, Amit
PMID: 30196356
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3618-3628.
Title: Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A.
Author: Messal, N|Fernandez, N|Dayot, S|Gratio, V|Nicole, P|Prochasson, C|Chantret, I|LeGuilloux, G|Jarry, A|Couvelard, A|Treton, X|Voisin, T|Ogier-Denis, E|Couvineau, A
PMID: 30251681
Journal: Cancer Epidemiol Biomarkers Prev. 2018 Oct 5. pii: 1055-9965.EPI-18-0121.
Title: Incremental Elevations in TNFalpha and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity.
Author: Pfalzer, Anna C|Leung, Keith|Crott, Jimmy W|Kim, Susan J|Tai, Albert K|Parnell, Laurence D|Kamanu, Frederick K|Liu, Zhenhua|Rogers, Gail|Shea, M Kyla|Garcia, Paloma E|Mason, Joel B
PMID: 30291114
Journal: Arch Med Res. 2018 Oct 9. pii: S0188-4409(18)30568-X.
Title: Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line.
Author: Nafees, Sana|Mehdi, Syed Hassan|Zafaryab, Mohammad|Zeya, Bushra|Sarwar, Tarique|Rizvi, Moshahid Alam
PMID: 30314650
Journal: Oncol Lett. 2018 Nov;16(5):6140-6146.
Title: CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFkappaB and/or caspase-3/7 signaling pathway.
Author: Zeng, Lifeng|Qian, Jinrong|Luo, Xiaojiang|Zhou, Aiqun|Zhang, Zhiyong|Fang, Quangang
PMID: 30344756
Journal: Cancer Biol Ther. 2018 Oct 25:1-11.
Title: Metformin inhibited colitis and colitis-associated cancer (CAC) through protecting mitochondrial structures of colorectal epithelial cells in mice.
Author: Wang, Shu-Qing|Cui, Shu-Xiang|Qu, Xian-Jun
PMID: 30359174